• 대한수의사회지
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• 제6권2호
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• pp.10-16
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• 1962

A rodenticide, sodium monofloroacetate, was administered to mice by introducing the rodenticide directly into the stomach, and the following observations were made. 1). Sings of intoxication were : incoordination and wobbly gait due to motor depression, d

• 대한임상독성학회지
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• 제9권2호
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• pp.113-116
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• 2011

Superwarfarin, such as brodifacoum, is a highly lethal vitamin K antagonist used as a rodenticide. Brodifacoum has a particularly long half-life in the body, which ranges to several months, and therefore requires prolonged treatment with antidotal vitamin K. We experienced a case whereby an 18-year-old male was presented to the hospital with a severe bleeding disorder. It was discovered that he had ingested brodifacoum rodenticide with intent to commit suicide. Despite continual treatment with vitamin K, the bleeding disorder persisted for several months before he recovered. We report this case with literature review.

• Journal of Pharmaceutical Investigation
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• 제6권2호
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• pp.83-87
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• 1976

Microanalysis of rodenticide by visible absorption method was attempted. The following procedure was found to be very simple and to give accurate results. RH-28787 was added to dimethylformamide (DMF), and extracted after stirring for about 20 minutes in extractor $(30^{\circ}C)$. After extraction, the absorbance of DMF solution, was measured at 346 nm by using spectrophotometer. The result agrees closely with the experimentally determined value by means of the gas chromatograph.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2009년도 춘계학술대회
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• pp.217-217
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• 2009

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 1977년도 제16차 학술대회
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• pp.95.1-95.1
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• 1977

• 농약정보
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• 제20권1호통권148호
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• pp.60-63
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• 1999

미국에서 농약을 판매하기 위해서는 먼저 해당농약을 등록하여야 하는데 등록업무는 연방 살충$\cdot$살균$\cdot$살서제법(FIFRA : Federal Insecticide, Fungicide and Rodenticide Act)에 의거, USDA(미농무성)에서 관장했으나 1970년 12월 이후부터 신설된 EPA(환경보호청)가 맡고 있다. 여기에 소개하는 내용은 Farm Chemicals Handbook 최근호(''98)의 부록(regulatory file)에 수록된 미국농약관리법중이 주요 내용이며 우리나라의 농약안전관리와 신농약개발 업무에 직$\cdot$간접으로 관계되는 모든 분들에게 참고가 되었으면 하는 바람으로 호에 걸쳐 소개한다.

• Archives of Pharmacal Research
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• 제18권4호
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• pp.277-281
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• 1995

An anticoagulant, 4-hydroxy-3-[1, 2, 3, 4-tetrahydro-3-[4-(4-trifluoromethylbenzyloxy)phenyll-1 -naphthyl]coumarin (Flocoumafen) was synthesized in 8 steps starting from phenylacetyl shloride and anisole. The key step in the synthesis involves the reaction of 3-(4-methoxyphenyl)-1-teralol with 4-hydroxycoumarin to give 4-hydroxy-3 [1, 2, 3, 4-tetrahydro-3-[4-emthoxyphenyl]-1-naphthyl]coumarin.

• Advances in environmental research
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• 제1권3호
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• pp.211-221
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• 2012

Bromadiolone (BRD), a second generation anticoagulant often applied to the living environment to control rodents, is usually considered to have low environmental toxicity due to its poor solubility in water. In this study of the effect of humic acid (HA) on BRD using electronic absorption spectroscopy, it has been observed that BRD is appreciably solubilized even in low concentrations of aqueous HA solutions. The BRD solubilization efficiency of aqueous HA was found to be $2.39{\pm}0.14$ ($4.53{\pm}0.26{\mu}M\;ppm^{-1}$). It was also seen that BRD is reasonably solubilized in aqueous extract of farm soil.

• Archives of Pharmacal Research
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• 제22권3호
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• pp.302-305
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• 1999

An efficient procedure for the preparation of 4-hydroxy-3-{1,2,3,4-tetra-hydro-3-[4-(4-trifluoromethylbenzyloxy)phenyl]-1-naphthyl}thiocoumarin (thioflocoumafen, 1a and 1b) is described. The key step in the synthesis involves the condensation reaction of 3-(4-methoxyphenyl)-1-tetralol (2) with 4-hydroxy-1-thiocoumarin (3).

• 한국임상수의학회지
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• 제20권2호
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• pp.245-247
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• 2003

4년령의 잉글리시쉽독이 4일간의 호흡곤란과 비출혈로 본 건국대학교 수의과대학 동물병원에 내원하였다. 항응고제인 살서제의 섭취는 vitamine K1의 재생을 방지하여 순환 응고인자의 활성을 감소시킨다. 따라서 살서제에 중독이 되었을 때, 빠르고 적절한 치료가 수행되지 않으면 심각한 출혈로 인해 의식불명에 빠지고 심지어는 생명을 위협하기도 한다. 본 증례에서는 의식혼탁과 후궁반장의 임상증상을 보이는 4년령의 중성화된 개의 성공적인 치료를 보고하고자 한다. 적절한 수혈요법과 vitamin K1를 이용한 효과적인 치료를 실시하여 임상증상의 현저한 개선을 보였으며, 환축은 현재 완치되어 건강한 삶을 살고 있다.