• Title/Summary/Keyword: Risk-Factor

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A modified Lee-Carter model based on the projection of the skewness of the mortality (왜도 예측을 이용한 Lee-Carter모형의 사망률 예측)

  • Lee, Hangsuck;Baek, Changryong;Kim, Jihyeon
    • The Korean Journal of Applied Statistics
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    • v.29 no.1
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    • pp.41-59
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    • 2016
  • There have been continuous improvements in human life expectancy. Life expectancy is as a key factor in an aging population and can wreak severe damage on the financial integrity of pension providers. Hence, the projection of the accurate future mortality is a critical point to prevent possible losses to pension providers. However, improvements in future mortality would be overestimated by a typical mortality projection method using the Lee-Carter model since it underestimates the mortality index ${\kappa}_t$. This paper suggests a mortality projection based on the projection of the skewness of the mortality versus the typical mortality projection of the Lee-Carter model based on the projection of the mortality index, ${\kappa}_t$. The paper shows how to indirectly estimate future t trend with the skewness of the mortality and compares the results under each estimation method of the mortality index, ${\kappa}_t$. The analysis of the results shows that mortality projection based on the skewness presents less improved mortality at an elderly ages than the original projection.

Plant uptake potential of endosulfan from soil by carrot and spinach (다소비 채소작물인 시금치와 당근의 토양 중 엔도설판 흡수이행능)

  • Choi, Geun-Hyoung;Jeong, Dong-Kyu;Lim, Sung-Jin;Ro, Jin-Ho;Ryu, Song-Hee;Park, Byung-Jun;Moon, Byung-Cheol;Kim, Jin Hyo
    • Journal of Applied Biological Chemistry
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    • v.60 no.4
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    • pp.339-342
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    • 2017
  • Residual endosulfan in an agricultural environment has been reported, although endosulfan was listed to persistent organic pollutants and banned. To produce the safe crop from endosulfan residue risk, the plant uptake potential of endosulfan from soil to crop should be studied. In here, the plant uptake potentials of endosulfan in various crops were surveyed and ranged from 0.002-4.460. And the bioconcentration factors (BCF) of total endosulfan in carrot and spinach were calculated from the pot experiment. The BCFs in carrot and spinach were 0.285 and 0.040-0.047 respectively. Endosulfan sulfate was contributed to over 42.8% of the crop residue as a major contributor among the three endosulfan congeners in both of carrot and spinach.

Residual characteristics and processing factors of azoxystrobin during eggplant and lettuce processing (가지와 상추의 가공 중 azoxystrobin의 잔류량 변화 및 가공계수)

  • Kim, Jeong-Ah;Seo, Jeong-A;Lee, Hye-Su;Im, Moo-Hyeog
    • Journal of Applied Biological Chemistry
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    • v.63 no.1
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    • pp.51-60
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    • 2020
  • This study was conducted to investigate changes in pesticide residues in eggplant and lettuce during washing and cooking processes after application with azoxystrobin. Eggplant was processed with running washing, steaming, and stir-frying, and lettuce was processed with soaking washing, running washing, soaking and running washing, ultrasonic cleaning, and blanching. The limit of quantitation of GC analysis of azoxystrobin was 0.01 mg/kg and the recovery rate was 84.7-109.5%. The azoxystrobin processing factors (PFs) and reduction rates in eggplant and lettuce were calculated and the results were as follows. In the case of eggplant, the azoxystrobin PF and reduction rate of running washing were 0.29 and 71.1%, respectively, those of steaming were 0.32 and 68.0%, respectively, and those of stir-frying were 0.24 and 75.7%, respectively. In the case of lettuce, the azoxystrobin PF and reduction rate of soaking washing were 0.25, 75.3%, those of running washing were 0.61 and 38.9%, respectively, those of soaking and running washing were 0.32, 68.0%, those of ultrasonic cleaning were 0.47 and 53.1%, respectively, and those of blanching were 0.26 and 73.6%, respectively. It could be identified that pesticide residues in eggplant and lettuce can be effectively reduced through washing and cooking processes and that most of pesticide residues were removed when cooking processes were undergone after washing. Therefore, azoxystrobin PFs after washing and processing can be provided as basic data for risk assessment.

A Study on the Determinants of Liporotein(a) Level - Primary, Middle, and High School Teachers in Seoul - (혈액내 Lipoprotein(a) 농도의 결정요인에 관한 연구 - 서울시 일부 초, 중, 고교 교사들을 대상으로 -)

  • 최현오;이용욱;나승식;이후장
    • Journal of Food Hygiene and Safety
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    • v.13 no.2
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    • pp.155-163
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    • 1998
  • The purpose of this study was to determine the association between blood lipids, fibrinogen, fasting blood sugar, lifestyle-related factors and lipoprotein(a). This study was performed with 140 healthy adults (male:80, female:60) among the teachers in primary, middle, and high school in Seoul in November 1996. Lipoprotein(a) concentration was measured with an enzyme-linked-immunosorbents assay(ELISA), and the results showed that the distribution was highly skewed and the average concentrations of male and female were $16.94{\pm}12.70\;mg/dL\;and\;17.92{\pm}7.58\;mg/dL$, respectively. The percentage of subject with lipoprotein(a) concentrations higher than 30 mg/dL was 26.4%. Univariate analysis showed significant association between lipoprotein(a) and age, alcohol, meat, and NaCl consumption (p<0.05). In multivariate analysis, lipoprotein(a) correlated positively with age (p<0.05) and meat consumption (p<0.01). These data suggest that lifestyle-related factors may affect the lipoprotein(a) concentration regarded as a risk factor of atherosclerosis disease.

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Introduction of Alien Plants on the Fill and Cut Slopes of the Road Construction in South Korea (우리나라에서 도로 공사장의 성토사면과 절토사면에서 외래식물의 도입)

  • Chu, Yeounsu;Jin, Seung-nam;Son, Deokjoo;Park, Shinyeong;Cho, Hyungjin;Lee, Hyohyemi
    • Ecology and Resilient Infrastructure
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    • v.6 no.4
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    • pp.191-199
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    • 2019
  • Road development is considered an important factor in invasion and dispersion of ailen plants by damaging the natural ecosystems and connecting the detached landscapes into long tubular structures. In this study, vegetation survey was carried out according to the topographical characteristics of cut slope, fill slope, and flat land at the construction site in order to understand the effect of road developemt on the change of the floristic composition of ailen plants. Road developement projects caused a lot of changes in annual and biennial alien plants because of continuous disturbances. Changes in species composition of alien plants decreased in the cut slope. On the other hand, the ailen palnts of the fill slope increased. The increase or decrease alien plants on flat land were identified depending on where it occurred, and no major trend was found. The cause of these change was driven by unintentionally introduced alien plants. In particular, the cut slope with a high occurence of unintentional ailen plants should not be used as a source of high-risk alien plants such as ecosystem disturbances. Since the transplanted species were intentionally planted by the landscape plan, it was possible to identify colonies from early stages and spread to the nearby flat land. Therefore, in order to minimize the impact of road slope vegetation on the surrounding ecosystem during and after road construction, it is suggested to plant high viability plants in the landscape design during the environmental impact assessment consultation.

Prognostic Value of Leptin in Terminally Ill Cancer Patients (말기암환자의 여명 예측 요인, 혈중 렙틴 농도의 효과)

  • Hong, Ji-Hyun;Lee, So-Jin;Kwak, Sang-Mi;Choi, Youn-Seon;Lee, June-Yeong
    • Journal of Hospice and Palliative Care
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    • v.15 no.2
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    • pp.99-107
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    • 2012
  • Purpose: Most terminally ill cancer patients die from cancer anorexia-cachexia syndrome. This study evaluated a prognostic role of plasma leptin levels in terminally ill cancer patients. Methods: This study enrolled 69 terminally ill cancer patients who were aged above 20 years old from July 2009 to July 2010. For univariate analysis, an association between leptin levels and patient's characteristics or other variables was examined using Spearman's correlation analysis, Wilcoxon's rank-sum test or Kruskal-Wallis test, as appropriately. For multivariable analysis, Cox's proportional hazard regression model was used to evaluate a clinical significance of plasma leptin levels as a prognostic factor and to determine factors which affect the risk of death in terminally ill cancer patients. Results: A statistically significant positive correlation between plasma leptin levels and survival time was found. Univariate Cox's proportional hazard regression analyses also showed a moderately significant association between plasma leptin levels and survival time. However, after adjusting variables for sex, white blood cell counts, total bilirubin, AST, ALT, albumin and CRP levels, plasma leptin levels were not significantly associated with survival time. Conclusion: No significant association was found between plasma leptin levels and survival time in terminally ill cancer patients. However, this study suggested a prognostic value of plasma leptin levels in gastrointestinal cancer patients.

Optimal Cutoff Points of Rate Pressure Product in Each Stage of Treadmill Exercise Test According to the Degree of Metabolic Syndrome in Korean Adults (한국성인의 대사증후군 예방을 위한 운동부하 검사시 각 단계별 심근부담률의 적정 임계점)

  • Shin, Kyung-A
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.2
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    • pp.136-143
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    • 2018
  • The rate pressure product (RPP) is expressed as a product of the heart rate and systolic blood pressure as an index indirectly measuring the myocardial oxygen consumption, and it indicates the burden on the myocardium. The aim of this study was to determine the optimal level of RPP for preventing metabolic syndrome in a treadmill exercise test in Korean adults. Metabolic syndrome was the diagnosis of the third executive summary report on the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) criteria. According to the criteria, the metabolic syndrome diagnosis group (MetS, N=25), pre-metabolic syndrome group (Pre-MetS, N=106), and non-risk factor group (Non-MetS, N=65) were classified. The exercise stress test was performed based on the Bruce protocol. The RPP was calculated as (heart rate${\times}$systolic blood pressure)${\div}1,000$. The results showed that the maximum systolic blood pressure was high despite the low daily dose reached in the diagnostic group of metabolic syndrome. The optimal threshold of the RPP at the time of the exercise treadmill test for a metabolic syndrome prediction was $12.56mmHg{\times}beats/min{\times}10^{-3}$ in the first stage of the exercise stress test. The second stage of the exercise test was $16.94mmHg{\times}beats/min{\times}10^{-3}$, and at the third stage of the exercise test was $21.11mmHg{\times}beats/min{\times}10^{-3}$.

High-Value Materials from Microalgae (미세조류 유래 고부가 유용물질)

  • 오희목;최애란;민태익
    • Microbiology and Biotechnology Letters
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    • v.31 no.2
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    • pp.95-102
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    • 2003
  • Microalgae are a diverse group of photosynthetic organisms and abundant in every ecosystem in the biosphere. They are common in aqueous environments including marine, brackish and fresh waters and in some habitats that lack eukaryotic life such as some hot springs and highly alkaline lakes. Microalgal biotechnology that is focused on the microalgae-based production of a variety of useful materials such as pharmaceutical comfounds, health foods, natural pigments, and biofuels is considered as an important discipline with the development of biotechnology. In addition, the mass cultivation of microalgae can also contribute to improving the environmental quality by reducing the concentration of $CO_2$ which is one of major gases lead to global warming. Consequently, it seems that the microalgae can be used as an efficient, renewable, environmentally friendly source of high-value biomaterials such as chemicals, pigments, energy, etc. and the microalgal biotechnology will most likely represent a larger portion of modern biotechnology.

GIS-based Subsidence Hazard Map in Urban Area (GIS 기반의 도심지 지반침하지도 작성 사례)

  • Choi, Eun-Kyeong;Kim, Sung-Wook;Cho, Jin-Woo;Lee, Ju-Hyung
    • Journal of the Korean Geotechnical Society
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    • v.33 no.10
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    • pp.5-14
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    • 2017
  • The hazard maps for predicting collapse on natural slopes consist of a combination of topographic, hydrological, and geological factors. Topographic factors are extracted from DEM, including aspect, slope, curvature, and topographic index. Hydrological factors, such as soil drainage, stream-power index, and wetness index are most important factors for slope instability. However, most of the urban areas are located on the plains and it is difficult to apply the hazard map using the topography and hydrological factors. In order to evaluate the risk of subsidence of flat and low slope areas, soil depth and groundwater level data were collected and used as a factor for interpretation. In addition, the reliability of the hazard map was compared with the disaster history of the study area (Gangnam-gu and Yeouido district). In the disaster map of the disaster prevention agency, the urban area was mostly classified as the stable area and did not reflect the collapse history. Soil depth, drainage conditions and groundwater level obtained from boreholes were added as input data of hazard map, and disaster vulnerability increased at the location where the actual subsidence points. In the study area where damage occurred, the moderate and low grades of the vulnerability of previous hazard map were 12% and 88%, respectively. While, the improved map showed 2% high grade, moderate grade 29%, low grade 66% and very low grade 2%. These results were similar to actual damage.

Research Trends of Work-Related Musculoskeletal Disorders in Korean Literature (작업관련성 근골격계 질환의 국내 연구동향분석)

  • Ko, Youn-Seok;Park, Hun-Sang;Lee, Jung-Han;Cha, Yun-Yeop;Chung, Won-Suk;Shin, Byung-Cheul;Jeon, Chan-Yong;Go, Ho-Yeon;Sun, Seong-Ho;Jang, Bo-Hyoung;Song, Yun-Kyung;Ko, Seong-Gyu
    • Journal of Korean Medicine Rehabilitation
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    • v.23 no.2
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    • pp.95-104
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    • 2013
  • Objectives : The purpose of this study is to analyze internal research trends of work-related musculoskeletal disorders(WMSDs) and provide problems of researches forward. Methods : 6 Korean databases were searched for articles of WMSDs published from 2000 to 2012, and 264 research were systematic reviewed. An analytical method was used descriptive statistics, an actual number and percentage. Results : The results of distribution by year were reported more than 20 articles after 2004, and 45 articles in 2009. Industrial classification distribution of research subjects the manufacturing industry was many most at the 84. Research contents in most description were 147 whether it was risk factor and relation. Research design type of articles was most description survey research 226. In the research field 89 articles were reported to the journal related to technologies. Conclusions : It is considered to be necessary that ergonomic approach would cooperate with other approaches such as integrated health management system as well as industrial medicine considering psychosocial factors.