• Nuclear Medicine and Molecular Imaging
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• 제43권3호
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• pp.222-228
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• 2009

Risk stratification and assessment of prognosis in patients with known or suspected CAD is of crucial important for the practice of contemporary medicine. Noninvasive testing such as myocardial perfusion scintigraphy, coronary artery calcium scoring or CT coronary angiography is increasingly being used to determine the need for aggressive medical therapy and to select patients for catheterization. The integrated anatomic and functional information may provide more additional information for the cardiologist or other clinician by the improved risk stratification and diagnostic accuracy of integrated techniques. The development of SPECT/CT or PET/CT hybrid systems is therefore of important value for the nuclear cardiology.

• Journal of Acupuncture Research
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• 제18권6호
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• pp.14-26
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• 2001

Objective : Stroke is a serious disease despite of the recent improvement in medical treatment. Hence, identification of modifiable risk factors for stroke is important. This case-control study was done to demonstrate that relation between risk factors(familial history of stroke, hypertension, diabetes mellitus and heart disease), lifestyle factors(alcohol drinking, psychologic stress, exercise, liking salty and hot foods) and the incidence of stroke. Methods : We interviewed 214 stroke patients(116 in men, 98 in women) as case group and 205 non-stroke patients(118 in men, 87 in women) as control group from January 1, 2001 to July 31, 2001 in oriental hospital of Kyung Hee medical center. We investigated risk factors, lifestyle factors of stroke in all patients and stroke-subtype of case group. Stroke-subtype consists of cerebral infarction and cerebral hemorrhage. Results : The percentage of familial history in the case group was significantly higher than that of control group, especially in the patients of cerebral infarction. The most ordinary preceding disease was hypertension. And the preceding disease of hypertension, diabetes mellitus was associated positively with the risk of stroke. The percentage of exercise was significantly higher than that of control group. The percentage of alcohol drinking, psychologic stress within 1 week and liking salty and hot foods was higher in the case group. However, there was no significant difference between case and control group. Conclusion : According to the above results, we found that familial history of stroke, preceding disease(hypertension, diabetes mellitus) affected to the incidence of stroke and exercise might be predisposing risk factors for stroke.

• Communications for Statistical Applications and Methods
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• 제30권1호
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• pp.21-35
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• 2023

Metabolic syndrome is a serious disease that can eventually lead to various complications, such as stroke and cardiovascular disease. In this study, we aimed to identify the risk factors related to metabolic syndrome for its prevention and recognition and propose a nomogram that visualizes and predicts the probability of the incidence of metabolic syndrome. We conducted an analysis using data from the Korea National Health and Nutrition Survey (KNHANES VII) and identified 10 risk factors affecting metabolic syndrome by using the Rao-Scott chi-squared test, considering the characteristics of the complex sample. A naïve Bayesian classifier was used to build a nomogram for metabolic syndrome. We then predicted the incidence of metabolic syndrome using the nomogram. Finally, we verified the nomogram using a receiver operating characteristic curve and a calibration plot.

• Asian Pacific Journal of Cancer Prevention
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• 제17권6호
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• pp.2973-2977
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• 2016

Opisthorchis viverrini is still a serious problem in Northeastern and Northern Thailand. Active surveillance is required to determine updated data for further prevention and control planning. Therefore, this study aimed to examine the prevalence and risk factors for O. viverrini in three provinces, Northeastern Thailand. A cross-sectional survey was conducted during October 2015 to March 2016 at Kaeng Sanam Nang district of Nakhon Ratchasima province, Waeng Noi district of Khon Kaen province, and Khon Sawan district of Chaiyaphum province, Thailand. Stool samples were examined by using a modified Kato-Katz Thick smear technique. From a total of 978 participants screened, O. viverrini infection was found in 1.74%, the majority opf positive cases being male (6.62%), age group 51-60 years old (4.21%), educated at primary school (8.43%), occupied with agriculture (9.62%),having an income <4,000 baht per month (4.82%), and living in Khon Sawan district (8.43%). Participants had a high knowledge level (42.43%), good attitude level (34.76%), and fair level (38.04%). The present study indicates the O. viverrini infection rate is low, but elderly males with primary school education involved in agriculture are still frequently effected particularly in Khon Sawan district. Therefore, this risk group requires behavior modification and continued monitoring.

• 대한한방내과학회지
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• 제31권3호
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• pp.569-577
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• 2010

Background & Objectives : Yellow fur on the tongue is known to be associated with prognosis of disease in oriental medicine. Higher ratios of low-density lipoprotein cholesterol(LDL) to high-density lipoprotein cholesterol(HDL) & total cholesterol (TC) to high-density lipoprotein cholesterol(HDL) are associated with a greater risk of cardiovascular disease. The aim of this study was to assess the relationship between cardiovascular disease index and yellow fur - oriental medical index - in stroke patients over 60 years old. Methods & Subjects : Among 802 of the recruited patients(434 male, 368 female), 340 were yellow fur group(209 male, 131 female). We assessed their general characteristics and risk factors. We compared the cardiovascular disease index between yellow fur and non-yellow fur groups by sex. Results : On the General Characteristics males have yellow fur more often than females. In cardiovascular disease index, the male yellow fur group showed higher ratios of TC/HDL(atherogenic index), (TC-HDL)/HDL, LDL/HDL and higher LDL and showed lower HDL than the non-yellow fur group. In female patients, there were no differences between the two groups about cardiovascular disease index. There were more patients diagnosed with Fire & Heat in the male yellow fur group, and Dampness & Phlegm in the male non-yellow fur group. The male yellow fur group eat fast food more than the non-yellow fur group. Conclusions : The results indicated that yellow fur may be associated with a high risk of cardiovascular disease. We can thus use yellow fur on the tongue as a cardiovascular disease index in male stroke patients over 60 years old.

• 한국인터넷방송통신학회논문지
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• 제23권4호
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• pp.127-135
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• 2023

요즘, 우울증 및 스트레스로 자살하는 환자가 급증하고 있다. 뿐만 아니라, 스트레스 및 우울증이 오래 지속되면, 심장병 및 뇌 질환, 고혈압 등을 유발할 수 있는 위험한 요소로 질환이다. 그러나, 아무리 현대 의학이 발전하였지만, 우울증 및 심장병 환자에게는 특별한 약이나 치료제가 없는 매우 난감한 상황이다. 그러므로, 세계 여러 나라에서, 심전도 및 산소포화도, 뇌파 분석 기능을 이용해서 우울증 위험환자 및 자살 위험환자를 조기에 판단하는 연구가 활발하게 이루어지고 있다. 본 논문에서는, 이러한 문제점을 분석하기 위해서, 심장병 가설데이터를 수립해서, 심장병 위험환자를 판단하는 컴퓨터 모의실험을 수행하였다. 특히, 심장병 발생 예측을 을 10% 이상 향상하게 시키기 위해서, 퍼지 추론을 사용하는 모의실험을 수행하였다.

• 한국융합학회논문지
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• 제2권4호
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• pp.47-52
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• 2011

치주질환(periodontal disease, 잇몸병)은 인구의 50%이상이 이환되는 만성질환이다. 치주질환을 치료하지 않으면, 치아 지지조직의 염증을 악화시켜 치아손실(tooth loss)을 가져온다. 고혈압은 성인의 30%에서 발병하며, 심혈관계통 질환의 이환(morbidity)과 사망(mortality)의 중요한 원인이다. 약 20년 전까지만 해도 두 가지 질환은 깊은 관련이 없어 보였지만, 최근 서로 연관성이 있다는 사실이 밝혀졌다. 심혈관계통의 위험요소에 대한 연구결과, 죽상경화증(atherosclerosis) 합병증 발생은 치주(periodontium) 질환과 관계가 있다. 즉, 뇌졸중(stroke), 관상동맥질환, 말초동맥질환에 대한 위험요소가 치주염이라는 증거가 있다. 이런 인과관계는 두 가지 질환이 서로 공통의 위험요소를 갖는다는 의미이다. C-reactive protein(CRP)은 치주염에서 증가하고, 치주질환 환자는 혈관운동 기능(vasomotor function)이 손상된다는 보고가 있었으며, 치주질환으로 인해 고혈압이 발생한다. 본 연구의 목적은 문헌 고찰을 통해, 치주염과 고혈압을 비롯한 심혈관계통 질환의 인과관계를 밝히고자 한다. 고혈압은 당뇨와 함께 대표적인 생활습관질병이기 때문에, 본 연구를 통해서 적절한 치아관리를 통해 고혈압으로 인한 여러 가지 합병증을 예방하고자 한다.

• 척추신경추나의학회지
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• 제13권2호
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• pp.35-46
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• 2018

Objectives : To determine the effectiveness of Chuna manual therapy(CMT) for Adult Visceral Diseases. Methods : To find evidence of CMT for adult digestive system disease, we used 9 electronic databases(Pubmed, CAJ, EMBASE, Cochrane Library, Web of Science, KISS, KISTI, NDSL, RISS) up to April 2018. We reviewed randomized control trials(RCTs) using Chuna for Digestive system disease. To assess the methodological quality of each RCT, we used the Cochrane risk of bias tool. Results : We identified 11 RCTs about irritable bowel syndrome, chronic ulcerative colitis, gastritis, gastroptosis, spleen entropathy, gastrointestinal dysfunction after stroke in 356 studies. All studies used total efficiency rate for main outcome. In all studies, CMT was effective for digestive system disease. Conclusions : CMT was effective for Digestive system disease. Risk of bias was high and the difference between the experimental group and the control group was not great. Considering that there were no reports of side effects, it seems possible to apply CMT to the treatment of adult digestive system disease.

• 한국치위생학회지
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• 제20권6호
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• pp.855-864
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• 2020

Objectives: The aim of this study was to investigate the effects of periodontal disease in menopausal women. Methods: We used data from the 7th (2016-2018) Korea National Health and Nutrition Examination Survey. The subjects of the study were 2,643 women aged 40 to 59 years who participated in the periodontal examination and answered a menses questionnaire. The data were analyzed using complex samples multivariate logistic regression to investigate the effects related to periodontal disease in menopausal women. Results: After adjusting for general characteristics, oral health behaviors, and health status, those aged 50-59 years had odds ratio (OR) for periodontal disease of 2.52 compared to those aged 40-49 years. Compared to those who brushed 3 or more times a day, those with less than 3 brushings a day had OR of 1.48. Those who smoked had a 3.00 higher risk of periodontal disease than those who were non-smokers. Further, those with glycosuria had a 2.26 higher risk of periodontal disease than those without glycosuria. Conclusions: In order to promote the oral health of menopausal women, it is suggested that comprehensive and systematic oral health education should be implemented considering various variables.

• Nutrition Research and Practice
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• 제13권5호
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• pp.393-398
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• 2019

BACKGROUND/OBJECTIVES: The association between tea consumption and risk of coronary heart disease (CHD) remains controversial. This study aimed to determine whether tea consumption has an effect on CHD risk in Chinese adults. SUBJECTS/METHODS: In this hospital-based case-control study, 267 cases of CHD and 235 non-CHD controls were enrolled. Blood samples from all cases were examined. Cardiac function indices (left ventricular ejection fraction, left ventricular end-diastolic dimension, lactate dehydrogenase, and creatine kinase of the muscle or brain type), blood lipid index (high-density lipoprotein cholesterol), and blood coagulation function indices (fibrinogen and activated partial thromboplastin time) were recorded. Tea consumption of study participants was assessed by a specifically designed questionnaire. The baseline characteristics of the study populations were recorded, and CHD-related biomarkers were detected. Differences in baseline characteristics of the study participants were examined using t-tests for continuous variables and chi-squared tests for categorical variables. Unconditional logistic regression was used to measure the association between tea and CHD. RESULTS: There were significant differences in cardiac function indices, blood lipid index, and blood coagulation indices between CHD cases and controls (P < 0.05). We found tea consumption reduced CHD risk in female participants (adjusted odds ratio (OR) = 0.484, 95% CI: 0.242-0.968, P = 0.0403). Regarding the type of tea consumed, the risk of CHD was reduced in women who drank partially fermented tea (adjusted OR = 0.210, 95% CI: 0.084-0.522, P = 0.0008). Analytic results for the amount of tea consumed per unit time showed CHD risk was reduced in women who consumed 1-2 cups of tea per day (adjusted OR = 0.291, 95% CI: 0.131-0.643, P = 0.0023). A tea-drinking frequency of > 6 days/week was beneficial for CHD prevention (adjusted OR = 0.183, 95% CI: 0.049-0.679, P = 0.0112). When analyzed according to the duration of tea consumption, the risk of CHD was reduced in participants who had been drinking tea for 10-20 years (adjusted OR = 0.360, 95% CI: 0.137-0.946, P = 0.0382). CONCLUSIONS: Tea consumption is associated with a reduced risk of CHD in female but not male populations in Guangzhou.