• Title/Summary/Keyword: Risk of Bias

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A Review of Chuna Manual Therapy for Tension Type Headache: Focusing on Pubmed and Korean Literature (긴장성 두통의 추나치료에 대한 임상 고찰: Pubmed와 국내문헌 중심으로)

  • Kim, Ju-Yong;Kim, Bo-Hyun;Kim, Hye-Bin;Yook, Tae-Han;Kim, Jong-Uk
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.11 no.1
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    • pp.1-10
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    • 2016
  • Objectives : The purpose of this study was to review the effectiveness of Chuna manual therapy for the treatment of tension type headache(TTH). Methods : All processes were independently carried out by three investigators. Literature search was performed in 3 databases(pubmed, OASIS, NDSL) from their inception to May 2016. Searched reports was twice excluded for title, abstract and body. And then, data extract and analysis was done before assessing risk of bias by Cochrane Handbook. Results : 11 RCT were included. Generally, Fascia Chuna therapy and Chuna spine & joint manipulation therapy were used for TTH. Except for 1 report, Chuna manual therapy was shown to be effective in treating TTH. In assessing risk of bias, because of the characteristic of intervention, blinding of participants was high risk of bias in most reports. Conclusions : Chuna manual therapy was shown to be effective in treating TTH. In korea, better designed trials with high quality is needed from now on.

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A Review of Recent Studies about Fire and Warm Needling for De Quervain Syndrome (드퀘르벵 증후군의 온침 및 화침 치료에 대한 최신 연구 동향)

  • Jeon, Seok-Hee;Shin, Jeong-Cheol
    • Korean Journal of Acupuncture
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    • v.38 no.4
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    • pp.222-234
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    • 2021
  • Objectives : The purpose of this study is to examine the efficacy of fire needling and warm needling for De Quervain Syndrome by reviewing clinical studies for recent 10 years. Methods : Randomized controlled trials, non-randomized controlled trials, and case series containing more than 20 cases about fire needling and warm needling for De Quervain Syndrome published since 2011 were searched through four foreign online databases (CNKI, Pubmed, EMBASE, Cochrane Library) and five Korean online databases (OASIS, Science ON, DBPIA, KISS, RISS). The number and characteristics of participants, treatment points and main treatment methods involving other combination treatments, treatment cycle or total periods of treatments, evaluation indices, efficacy, and adverse events were analyzed. Risk of bias of included randomized clinical trials was assessed using a revised tool for assessing risk of bias in randomized trials (RoB 2). Results : A total of 6 randomized clinical trials and 2 case series involving 471 participants were included. Tender point or 'Ashi point' was the most commonly used treatment point, followed by LU4. Treatment frequency ranged from once a day to once a week. One to three outcome measures were used to evaluate the results of the studies, with the efficacy rate the most frequently used, followed by visual analogue scale. Overall risk of bias of all included randomized clinical trials was judged to have some concerns. Conclusions : All selected studies showed that fire needling and warm needling treatments for De Quervain syndrome were more effective than other clinical methods or acupuncture treatments. However, as the number of clinical studies is still too small and the risk of bias of the studies is not low, it is believed that more systematic and objective studies should be conducted.

Flood Risk Assessment Based on Bias-Corrected RCP Scenarios with Quantile Mapping at a Si-Gun Level (분위사상법을 적용한 RCP 시나리오 기반 시군별 홍수 위험도 평가)

  • Park, Jihoon;Kang, Moon Seong;Song, Inhong
    • Journal of The Korean Society of Agricultural Engineers
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    • v.55 no.4
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    • pp.73-82
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    • 2013
  • The main objective of this study was to evaluate Representative Concentration Pathways (RCP) scenarios-based flood risk at a Si-Gun level. A bias correction using a quantile mapping method with the Generalized Extreme Value (GEV) distribution was performed to correct future precipitation data provided by the Korea Meteorological Administration (KMA). A series of proxy variables including CN80 (Number of days over 80 mm) and CX3h (Maximum precipitation during 3-hr) etc. were used to carry out flood risk assessment. Indicators were normalized by a Z-score method and weighted by factors estimated by principal component analysis (PCA). Flood risk evaluation was conducted for the four different time periods, i.e. 1990s, 2025s, 2055s, and 2085s, which correspond to 1976~2005, 2011~2040, 2041~2070, and 2071~2100. The average flood risk indices based on RCP4.5 scenario were 0.08, 0.16, 0.22, and 0.13 for the corresponding periods in the order of time, which increased steadily up to 2055s period and decreased. The average indices based on RCP8.5 scenario were 0.08, 0.23, 0.11, and 0.21, which decreased in the 2055s period and then increased again. Considering the average index during entire period of the future, RCP8.5 scenario resulted in greater risk than RCP4.5 scenario.

Chuna Manual Therapy Alone for Cervicogenic Dizziness: A Systematic Review (추나 단독 치료의 경추성 현훈에 대한 효과: 체계적 문헌 고찰)

  • Shin, Seon-Ho;Min, Kyung-Jin;Kim, Eui-Byeol;Ha, Won-Bae;Ko, Youn-Seok
    • Journal of Korean Medicine Rehabilitation
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    • v.29 no.1
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    • pp.1-6
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    • 2019
  • Objectives The purpose of this study is to provide an evidence base for the effectiveness of Chuna manual therapy (CMT) alone for cervicogenic dizziness. Methods We conducted a search up to October 2018 in 7 electronic databases. The randomized controlled trials (RCTs) that performed CMT for cervicogenic dizziness were included. The risk of bias was assessed using the Cochrane risk of bias tool. Results Ten RCTs met the inclusion criteria. The meta-analysis of 4 RCTs showed favorable results for the use of CMT alone compared to medication. Conclusions In 10 RCTs, we found that CMT was effective in cervicogenic dizziness. However, most of the included RCTs were unclear risk of bias. Therefore, well designed RCTs would be needed to obtain the stronger evidence level of CMT for cervicogenic dizziness.

Chuna Manual Therapy for Tinnitus : A Systematic Review and meta-analysis (이명에 대한 추나요법의 효과 : 체계적 문헌고찰과 메타분석)

  • Chung, In-Che;Cha, Yun-Yeop;Heo, In
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.14 no.1
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    • pp.13-23
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    • 2019
  • Objectives : The purpose of this study was to evaluate the effectiveness of Chuna manual therapy (CMT) for the treatment of tinnitus. Methods : We performed a literature search using eight electronic databases, using related keywords, from January 1990 until the end of April 2019. The randomized controlled trials (RCTs) which evaluated the effectiveness of CMT in the treatment of tinnitus were included in this study. The risk of bias were evaluated using the Cochrane risk of bias tool. Results : Five appropriate RCTs were included and analyzed. The efficacy rate of the CMT group was statistically significantly higher (P<0.03) versus the control group treated with Western medicine, acupuncture, and herbal medicine-only. Conclusions : In this literature review, there was sufficient evidence that CMT is more effective than conventional therapy (including Western medicine, acupuncture, and herbal medicine) in treating tinnitus. However, it should be considered that the included studies lacked any reference of the risk of bias

Ginseng for managing menopause symptoms: a systematic review of randomized clinical trials

  • Kim, Myung-Sunny;Lim, Hyun-Ja;Yang, Hye Jeong;Lee, Myeong Soo;Shin, Byung-Cheul;Ernst, Edzard
    • Journal of Ginseng Research
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    • v.37 no.1
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    • pp.30-36
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    • 2013
  • The aim of this review was to assess the effectiveness of ginseng as a treatment option for managing menopause symptoms. We searched the literature using ll databases from their inception to 26 September 2012 and included all randomised clinical trials (RCTs) that compared any type of ginseng to a placebo controls in postmenopausal women. The methodological quality of all studies was assessed using a Cochrane risk of bias tool. Four RCTs met our inclusion criteria. Most RCTs had high risk of bias. One RCT showed that Korean red ginseng (KRG) significantly improved sexual arousal and global health compared with placebo. Another RCT reported the superiority of KRG over placebo for treating menopause symptoms on Kupperman's index and menopausal rating score. The third RCT failed to show a significant effect of KRG on hot flash frequency compared to placebo. The fourth RCT found beneficial effects of ginseng compared to placebo on depression and well-being. In conclusion, the evidence on ginseng as an effective treatment for managing menopause symptoms is limited. Most of the RCTs are burdened with a high risk of bias. Thus firm conclusions cannot be drawn. Rigorous studies seem warranted.

Muscle Energy Technique for Neck Pain: Systematic Review (경추통에 대한 근 에너지 기법의 효과: 체계적 문헌고찰)

  • Son, Bu-Kyung;Yoo, Hyo-Jeong;Geum, Ji-Hye;Lee, Jung-Han;Ha, Won-Bae
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.15 no.1
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    • pp.49-64
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    • 2020
  • Objectives : The purpose of this study was to provide a clinical evidence base for the effectiveness of the muscle energy technique (MET) for cervicalgia. Methods : We conducted a search of 10 electronic databases up to April 2019. Randomized controlled trials (RCTs) that performed the MET for cervicalgia were included. The risk of bias was assessed using the Cochrane risk of bias (RoB) tool. Results : Six RCTs met the inclusion criteria. The literature review of these studies showed favorable results for the use of the MET in comparison to other manual medicines. Conclusions : In 6 RCTs, we found that the MET was effective in cervicalgia treatment. However, most of the included studies had an unclear risk of bias. Therefore, well-designed RCTs are necessary to obtain a higher evidence level of the MET use in cervicalgia.

The effectiveness of the supplementary use of the XP-endo Finisher on bacteria content reduction: a systematic review and meta-analysis

  • Ludmila Smith de Jesus Oliveira;Rafaella Mariana Fontes de Braganca;Rafael Sarkis-Onofre;Andre Luis Faria-e-Silva
    • Restorative Dentistry and Endodontics
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    • v.46 no.3
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    • pp.37.1-37.11
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    • 2021
  • Objectives: This systematic review evaluated the efficacy of the supplementary use of the XP-endo Finisher on bacteria content reduction in the root canal system. Materials and Methods: In-vitro studies evaluating the use of the XP-endo Finisher on bacteria content were searched in four databases in July 2020. Two authors independently screened the studies for eligibility. Data were extracted, and risk of bias was assessed. Data were meta-analyzed by using random-effects model to compare the effect of the supplementary use (experimental) or not (control) of the XP-endo Finisher on bacteria counting reduction, and results from different endodontic protocols were combined. Four studies met the inclusion criteria while 1 study was excluded from the meta-analysis due to its high risk of bias and outlier data. The 3 studies that made it to the meta-analysis had an unclear risk of bias for at least one criterion. Results: No heterogeneity was observed among the results of the studies included in the meta-analysis. The study excluded from the meta-analysis assessing the bacteria counting deep in the dentin demonstrated further bacteria reduction upon the use of the XP-endo Finisher. Conclusions: This systematic review found no evidence supporting the supplementary use of the XP-endo Finisher on further bacteria counting the reduction in the root canal.

Chuna Manual Therapy for Spondylolisthesis: A Systematic Review and Meta-analysis (척추전방전위증의 추나 치료에 대한 체계적 문헌 고찰 및 메타 분석)

  • Hong, Su Min;Ha, Hyun Ju;Yoon, Kwang Sik
    • Journal of Korean Medicine Rehabilitation
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    • v.30 no.4
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    • pp.65-77
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    • 2020
  • Objectives This study is aimed to evaluate the effectiveness of Chuna therapy for spondylolisthesis. Methods We searched th following 10 online databases without a language restriction (National Digital Science Library [NDSL], Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS], KMBASE, MEDLINE/PubMed, Cochrane library, Ebscohost, EMBASE, Ovid, China National Knowledge Infrastru [CNKI]) to find randomized controlled trials that used Chuna therapy for spondylolisthesis. The methodological quality of each randomized controlled clinical trial was assessed using the Cochrane risk of bias tool and meta-analyses were perfomed. Results Eleven randomized controlled trials were included. Chuna therapy showed statistically significant reduction of symptoms. Meta-analysis showed positive results for Chuna therapy for spondylolisthesis in terms of therapeutic effects to traction, chinese medicine, therapeutic exercise. Conclusion In this study, we reviewed studies about Chuna therapy used for spondylolisthesis. The studies showed that Chuna therapy can significantly effective on spondylolisthesis. But according to Cochrane risk of bias evaluation method, most of the studies's risk of bias were unclear. Therefore, more high-quality studies will be needed.

Effects of Chuna Manual Therapy(CMT) on Rotator Cuff Disorder: A Systematic Review (회전근개 질환에 대한 추나 치료의 효과: 체계적 문헌 고찰)

  • Hong, Su-Min;Do, Ki-Won;Yoon, Kwang-Sik
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.16 no.1
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    • pp.1-11
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    • 2021
  • Objectives This study aimed to evaluate the efficacy of Chuna manual therapy(CMT) in the treatment of rotator cuff disorder. Methods We searched th following nine online databases without language restriction (MEDLINE/PubMed, Cochrane library, Ebscohost, CNKI, RISS, NDSL, KMBASE, and KISS) to identify randomized controlled trials (RCTs) that used CMT in the treatment of rotator cuff disorder. The methodological quality of each RCT was assessed using the Cochrane risk-of-bias tool. Results Four RCTs were included. in the meta-analysis. CMT resulted in a significant reduction in symptoms in these trials. However, there was a high risk of bias in the RCTs. Conclusions We reviewed RCTs that studied the effects of CMT for rotator cuff disorder. While the studies indicate that CMT has favorable effects on rotator cuff disorder. But the risk of bias for most of the studies was high. Therefore, high-quality studies are required to make further conclusions.