• Toxicological Research
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• 제6권1호
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• pp.63-73
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• 1990

Human exposure to environmental carcinogens can be detected by a number of methods including immunoassay, $^{32}P-postlabeling$ assay, and fluorescence technique. These assays have been applied to measure biological markers of carcinogen-adducts formed with macromolecules such as DNA, RNA and protein. In an attempt to investigate causal relationships between carcinogen exposure and tumor formation, specific carcinogen-adducts have been quantitated from human tissues and body fluids of cancer patients, occupational workers heavily exposed to certain carcinogens, smokers and controls. Carcinogens studied for biological human monitoring include benzo(a)pyrene, aflatoxin B1, UV light, ethylene oxide, 8-methoxypsoralen, 4-aminobiphenyl, vinyl choride, N-nitrosamine, cisplatin and other chemotherapeutic agents. Relevance of human monitoring for cancer research, progress in this field, methods to detect carcinogen-adducts are reviewed here. It is hoped that these approaches will be used for the risk assessment of carcinogen exposure, cancer etiology study and cancer prevention in humans.

• Toxicological Research
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• 제6권1호
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• pp.61-61
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• 1990

Human exposure to environmental carcinogens can be detected by a number of methods including immunoassay, $^{32}P$-postlabeling assay, and fluorescence technique. These assays have been applied to measure biological markers of carcinogen-adducts formed with macromolecules such as DNA, RNA and protein. In an attempt to investigate causal relation ships between carcinogen exposure and tumor formation, specific carcinogen-adducts have been quantitated from human tissues and body fluids of cancer patients, occupational workers heavily exposed to certain carcinogens, smokers and controls. Carcinogens studied for biological human monitoring include benzo(a)pyrene, aflatoxin B1, UV light, ethylene oxide, 8-methoxypsoralen, 4-aminobiphenyl, vinyl chloride, N-nitrosamine, cisplatin and other chemotherapeutic agents. Relevance of human monitoring for cancer research, progress in this field, methods to detect carcinogen-adducts are reviewed here. It is hoped that these approaches will be used for the risk assessment of carcinogen exposure, cancer etiology study and cancer prevention in humans.

• 한국임상수의학회지
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• 제16권2호
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• pp.422-427
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• 1999

We are proposed for the computation of disease frequency measures and of their associated variances from data collected through prospective study of multiple dynamic cohort (herds) with a National Animal Health Monitoring System (NAHMS) in Gyeongnam. We can be estimated and calculated the annual incidence density for a group of herds and the 1-month risk of disease from the same within herd measure of monthly incidence density. We are proposed that the choice of measure to be estimated depend on the intended use of the information. From results in this study, Our study demonstrate that risk estimates are appropriates for producers and clinic veterinarian making decisions at the animal or herd level. Incidence density measures are appropriate for extrapolation to reference populations used for state and regional-level decision making.

• 상하수도학회지
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• 제33권4호
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• pp.259-268
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• 2019

One of the most effective methods to consistently ensure the safety of a tap water supply can be achieved by application of a comprehensive risk assessment and risk management approach for drinking water supply systems. This approach can be termed water safety plans(WSP) which recommended by WHO(world health organization) and IWA(international water association). For the introduction of WSP into Korea, 150 hazards were identified all steps in drinking water supply from catchment to consumer and risk assessment tool based on frequency and consequence of hazards were developed. Then, developed risk assessment tool by this research was implemented at a water treatment plant($Q=25,000m^3/d$) to verify its applicability, and several amendments were recommended; classification of water source should be changed from groundwater to stream to strengthen water quality monitoring contaminants and frequencies; installation of aquarium to monitor intrusion of toxic substances into raw water; relocation or new installation on-line water quality analyzers for efficient water quality monitoring; change of chlorination chemical from solid phase($Ca(OCl)_2$) to liquid phase(NaOCl) to improve soundness of chlorination. It was also meaningful to propose hazards and risk assessment tool appropriate for Korea drinking water supply systems through this research which has been inconsistent among water treatment authorities.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2019년도 춘계학술대회
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• pp.403-405
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• 2019

스마트 농업에 대한 기준 모델, 서비스 능력, 네트워크 능력에 대한 기술 표준화 과정을 추진해 오는 과정에서 현안으로 떠오르는 내용이 병충해, 전염병과 같은 위기상황이 가져올 수 있는 영향에 대한 우려였다. 동물의 감염요인인 구제역, 조류 인플루엔자 등의 위기요인들은 경제적 손실은 물론 인간의 사회활동에도 많은 제약을 가져와 국가경제에 막대한 영향을 끼치게 되었다. 본 논문에서는 이러한 인적요인, 자연재해 및 동물 감염 등의 위기로 인한 ICT 해결 방안인 네트워크 기반에서의 위기완화 서비스의 표준화 로드맵을 제시하여 표준기술을 적용 이러한 문제를 해결하는데 긍정적 요소로 작용할 것으로 판단된다.

• 대한의용생체공학회:의공학회지
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• 제44권1호
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• pp.19-24
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• 2023

Due to the spread of COVID-19, many patients with severe respiratory diseases have occurred worldwide, and accordingly, the use of mechanical ventilators has exploded. However, hospitals do not have systematic risk management, and the Medical Device Regulation also provides medical device risk management standards for manufacturers, but does not apply to devices in use. In this paper, we applied the Failure Mode Effects Analysis (FMEA) risk analysis technique based on the International Standard ISO 14971 (Medical Devices-Application of risk management to medical devices) for 85 mechanical ventilators of a specific model in use in hospitals. Failure modes and effects of each parts were investigated, and risk priority was derived through multiplication of each score by preparing criteria for severity, occurrence, and detection for each failure mode. As a result, it was confirmed that the microprocessor-based Patient Unit/Monitoring board in charge of monitoring scored the highest score with 36 points, and that reliability management is possible through systematic risk management according to priority.

• Structural Monitoring and Maintenance
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• 제7권1호
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• pp.59-67
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• 2020

This study aims to develop the fuzzy risk assessment model of the debris flow to verify the accuracy of risk assessment in order to help related organizations reduce losses caused by landslides. In this study, actual cases of landslides that occurred are utilized as the database. The established models help us assess the occurrence of debris flows using computed indicators, and to verify the model errors. In addition, comparisons are made between the models to determine the best one to use in practical applications. The results prove that the risk assessment model systems are quite suitable for debris flow risk assessment. The reproduction consequences of highlight point discovery are shown in highlight guide coordinating toward discover steady and coordinating component focuses and effectively identified utilizing these two systems, by examining the variety in the distinguished highlights and the element coordinating.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2019년도 춘계학술대회
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• pp.171-172
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• 2019

본 논문에서는 위험 발생상황에서 모니터링 객체에 대한 웹 지도 탐색 개발을 위하여 동적인 방식을 고려한다. 객체의 이동에서 관리시스템의 위치 인식 메카니즘을 기반으로 위험상황에 대해 위치를 실시간적으로 인식할 수 있도록 한다.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2006년도 추계 학술발표회
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• pp.509-514
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• 2006

Considering the risk management, there are many examples and various studies for the corporation risk. However, I have never seen the project risk management that applied a construction site for practical approach. Therefore, I have developed a chart (I-Chart) for the project risk management, and also built a model (I-Chart scenario analysis) that I could use. I applied this model to container yard reclaimed land in harbor construction with approaching of geotechnical engineering.

• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2006년도 춘계학술대회 논문집
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• pp.89-90
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• 2006