• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.12
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• pp.918-923
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• 2018

The main function of a fuel tank is to store fuel. On the other hand, the structural soundness of the fuel tank is related directly to the survival of the crew in an emergency situation, such as an aircraft crash, and the relevant performance is demonstrated by a crash impact test. Because crash impact tests have a high risk of failure due to the high impact loads, various efforts have been made to minimize the possibility of trial and error in the actual test at the beginning of the design. Numerical analysis performed before the actual test is a part of such efforts. For the results of numerical analysis to be reflected in the design, however, the reliability of numerical analysis needs to be ensured. In this study, the results of numerical analysis and actual test data were compared to ensure the reliability of numerical analysis for the crash impact test of a rotorcraft fuel tank. For the numerical analysis of a crash impact test, LS-DYNA, crash analysis software, was used and the ALE (arbitrary Lagrangian Eulerian) technique was applied as the analysis method. To obtain actual test data, strain gages were installed on the metal fittings of the fuel tank and linked to the data acquisition equipment. The strain and stress of the fuel tank fitting were calculated by numerical analysis. The reliability of the numerical analysis was enhanced by assessing the error between the strain measurement of the upper fitting obtained from an actual fuel tank and the strain calculated from numerical analysis.

• Journal of the Korean Society of Marine Environment & Safety
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• v.27 no.2
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• pp.238-246
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• 2021

Collision of small vessels such as fishing boats cause great personal injury. Prior to this study, the collision prevention algorithm was developed to assess the collision risk and make the collision alarm. However, a service provided for safety, such as a collision warning, not only prevents risks, but also requires a certain degree of user satisfaction to function effectively. In this study, the collision prevention algorithm for small vessels was improved to be more practical, and the effects of the improvement were confirmed by applying the algorithm. A survey conducted on the users of the collision warning service confirmed the user requirements for improving the accuracy of the collision warning system and reducing the volume and number of alarms. Accordingly, the algorithm was improved for user satisfaction, and the actual vessel experiment was performed applying the improved algorithm in an actual maritime environment. As a result, the frequency of alarm occurrence decreased compared to former algorithm, but the alarm was relatively steadily generated in dangerous situations. It was analyzed that the accuracy and practicality of the collision alarm were improved. If the practicality and reliability of the improved algorithm are verified in the further study, it will be able to effectively contribute to the prevention of collisions of small vessels.

• Molecules and Cells
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• v.44 no.1
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• pp.38-49
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• 2021

Airway mucus secretion is an essential innate immune response for host protection. However, overproduction and hypersecretion of mucus, mainly composed of the gel-forming MUC5AC protein, are significant risk factors for patients with asthma and chronic obstructive pulmonary disease (COPD). The transforming growth factor β (TGFβ) signaling pathway negatively regulates MUC5AC expression; however, the underlying molecular mechanism is not fully understood. Here, we showed that TGFβ significantly reduces the expression of MUC5AC mRNA and its protein in NCI-H292 cells, a human mucoepidermoid carcinoma cell line. This reduced MUC5AC expression was restored by a TGFβ receptor inhibitor (SB431542), but not by the inhibition of NF-κB (BAY11-7082 or Triptolide) or PI3K (LY294002) activities. TGFβ-activated Smad3 dose-dependently bound to MUC5AC promoter. Notably, TGFβ-activated Smad3 recruited HDAC2 and facilitated nuclear translocation of HDAC2, thereby inducing the deacetylation of NF-κB at K310, which is essential for a reduction in NF-κB transcriptional activity. Both TGFβ-induced nuclear translocation of Smad3/HDAC2 and deacetylation of NF-κB at K310 were suppressed by a Smad3 inhibitor (SIS3). These results suggest that the TGFβ-activated Smad3/HDAC2 complex is an essential negative regulator for MUC5AC expression and an epigenetic regulator for NF-κB acetylation. Therefore, these results collectively suggest that modulation of the TGFβ1/Smad3/HDAC2/NF-κB pathway axis can be a promising way to improve lung function as a treatment strategy for asthma and COPD.

• Therapeutic Science for Rehabilitation
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• v.10 no.3
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• pp.43-56
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• 2021

Objective : The objective of this study was to present the components of frailty by organizing the definitions of frail elderly and analyzing the tools used to screen them. Methods : This study searched for articles at involved frailty screening assessments in the elderly. Databases including CINAHL, Embase, Medline Complete, and PubMed were searched. The search terms were "assess" AND "frailty" AND "screening" AND ("frail elderly" OR "elderly"). Results : A total of 539 articles were identified by the search and 11 articles were selected. Frailty occurs due to the depressed function of multidimensional factors, and a frail elderly person is defined as one at high risk of health degeneration, functional impairment, and occurrence of disability, and having a high level of threat to life. Seven tools were selected from 11 articles. The most frequently used tool was the frailty phenotype, which was used in five articles (45.4%). The identified components of frailty were physical, activity participation, nutrition, psychological, social, overall health, and age. Conclusion : The results confirmed the definition and components of frailty. This study is expected to contribute to the future development of standardized evaluation tools for screening frail elderly individuals and intervention programs for the management of the frail elderly.

• Journal of Korean Neurosurgical Society
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• v.64 no.5
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• pp.791-798
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• 2021

Objective : The period of mechanical ventilator (MV)-dependent respiratory failure after cervical spinal cord injury (CSCI) varies from patient to patient. This study aimed to identify predictors of MV at hospital discharge (MVDC) due to prolonged respiratory failure among patients with MV after CSCI. Methods : Two hundred forty-three patients with CSCI were admitted to our institution between May 2006 and April 2018. Their medical records and radiographic data were retrospectively reviewed. Level and completeness of injury were defined according to the American Spinal Injury Association (ASIA) standards. Respiratory failure was defined as the requirement for definitive airway and assistance of MV. We also evaluated magnetic resonance imaging characteristics of the cervical spine. These characteristics included : maximum canal compromise (MCC); intramedullary hematoma or cord transection; and integrity of the disco-ligamentous complex for assessment of the Subaxial Cervical Spine Injury Classification (SLIC) scoring. The inclusion criteria were patients with CSCI who underwent decompression surgery within 48 hours after trauma with respiratory failure during hospital stay. Patients with Glasgow coma scale 12 or lower, major fatal trauma of vital organs, or stroke caused by vertebral artery injury were excluded from the study. Results : Out of 243 patients with CSCI, 30 required MV during their hospital stay, and 27 met the inclusion criteria. Among them, 48.1% (13/27) of patients had MVDC with greater than 30 days MV or death caused by aspiration pneumonia. In total, 51.9% (14/27) of patients could be weaned from MV during 30 days or less of hospital stay (MV days : MVDC 38.23±20.79 vs. MV weaning, 13.57±8.40; p<0.001). Vital signs at hospital arrival, smoking, the American Society of Anesthesiologists classification, Associated injury with Injury Severity Score, SLIC score, and length of cord edema did not differ between the MVDC and MV weaning groups. The ASIA impairment scale, level of injury within C3 to C6, and MCC significantly affected MVDC. The MCC significantly correlated with MVDC, and the optimal cutoff value was 51.40%, with 76.9% sensitivity and 78.6% specificity. In multivariate logistic regression analysis, MCC >51.4% was a significant risk factor for MVDC (odds ratio, 7.574; p=0.039). Conclusion : As a method of predicting which patients would be able to undergo weaning from MV early, the MCC is a valid factor. If the MCC exceeds 51.4%, prognosis of respiratory function becomes poor and the probability of MVDC is increased.

• Smart Media Journal
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• v.9 no.4
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• pp.176-186
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• 2020

The size and shape of crops are diverse, and the growing environment is also different. Therefore, when one uses a drone to spray pesticides, the characteristics of each crop must be considered, and flight conditions such as the flight height and forwarding velocity of the drone should be changed. The droplet flow of pesticides is affected by various flight conditions, and a large change occurs in the sprayed area. As a result, an uneven distribution of liquid may be formed at the wake, and the transport efficiency will be decreased as well as there would be a risk of toxic scatter. Therefore, this paper analyzes the degree of distribution of pesticides to the crops through numerical analysis when pesticide is sprayed onto the selected three crops with different characteristics by using agricultural drones with different flight conditions. On the purpose of establishing a guideline for spraying pesticides using a drone in accordance with the characteristics of crops, this paper compares the amount of pesticides distributed in the crops at the wake of nozzle flow using the figure of merit, and the sum of transported liquid rate divided by the root mean square of the probability density function.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.25 no.1
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• pp.41-55
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• 2022

Social interest in the fine particulate matter has increased significantly since the 2010s, and various efforts have been made to reduce it through environmental plans and policies. To support such environmental planning, in this study, spatial cluster characteristics of fine particulate matter (PM2.5) concentrations were analyzed in the metropolitan area to identify high-risk areas spatially, and the correlation with local environmental characteristics was also confirmed. The PM2.5 concentration for the recent 5 years (2016-2020) was targeted, and representative spatial statistical methods Getis-Ord Gi^* and Local Moran's I were applied. As a result of the analysis, the cluster form was different in Getis-Ord Gi^* and Local Moran's I, but they show high similarity in direction, therefore complementary results could be obtained. In the high concentration period, the hotspot concentration of the Getis-Ord Gi* method increased, but in Local Moran's I, the HH region, the high concentration cluster, showed a decreasing trend. Hotspots of the Getis-Ord Gi^* technique were prominent in the Pyeongtaek-Hwaseong and Yeoju-Icheon regions, and the HH cluster of Local Moran's I was located in the southwest, and the LL cluster was located in the northeast. As in the case of the metropolitan area, in the results of Seoul, there was a phenomenon of division between the northeast and southwest regions. The PM2.5 concentration showed a high correlation with the elevation, vegetation greenness and the industrial area ratio. During the high concentration period, the relation with vegetation greenness increased, and the elevation and industrial area ratio increased in the case of the annual average. This suggests that the function of vegetation can be maximized at a high concentration period, and the influence of topography and industrial areas is large on average. This characteristic was also confirmed in the basic statistics for each major cluster. The spatial clustering characteristics of PM2.5 can be considered in the national land and environmental plan at the metropolitan level. In particular, it will be effective to utilize the clustering characteristics based on the annual average concentration, which contributes to domestic emissions.

• Journal of Appropriate Technology
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• v.6 no.2
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• pp.219-225
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• 2020

Importance of touch equipment and smart learning increases and public institutions and educational facilities are applying smart devices to their daily environments. However, users of public smart devices are at risk of being exposed to the direct and indirect spread of infectious diseases. This study develops an exo-finger that wraps the fingertips of smart device users and is intended to have a disease prevention effect when used on public equipment. An exoskeletal body was fabricated by inserting a secondary material which is a mixture of the activating material, carbon black (CB) and a macromolecular polymer (elastomer) into a mold. This device was confirmed to have a touch function when the CB content was 0.030 wt% or higher, and the content of the elastomer was varied so that it could have a friction force similar to that when a person touches a smart device (a friction coefficient of 2.5). Through experiments, it was concluded that the CB content had little effect on the friction coefficient. As a result of testing the completed prototype on a smart device, it was proven that the developed exoskeletal device can be useful in situations where it is impossible to touch due to wearing protective gears, or when equipment such as gloves is used to prevent the spread of infectious diseases.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.3
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• pp.37-45
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• 2021

Purpose : This study aimed to present normative data and cut-off points for older Korean adults completing the Montreal Cognitive Assessment - Korean (MoCA-K), which is used as a screening test for mild cognitive impairment in Korea. Methods : A total of 195 healthy adults ≥60 years were recruited. All participants completed the MoCA-K and the Korean - Mini-Mental State Examination (MMSE-K) to assess their cognitive function. Participants were divided into six groups based on their age: 60-64 years, 65~69 years, 70~74 years, 75~79 years, 80~84 years, and 85~89 years. Results : The results revealed that MoCA-K score decreased significantly with age (mean score ± standard deviation [SD]; 27.63±2.80 in subjects aged 60~64 years; 27.00±2.39 in subjects aged 65~69 years; 24.94±2.96 in subjects aged 70~74 years; 24.74±3.37 in subjects aged 75~79 years; 22.59±4.72 in subjects aged 80~84 years; and 18.83±5.38 in subjects aged 85~89 years; p<.001). Additionally, MoCA-K score also increased significantly with educational level (mean score±standard deviation [SD]; 19.95±4.78 in no formal education group; 24.95±2.22 in elementary school graduated group; 26.35±2.72 in middle school graduated group; 28.32±1.36 in high school graduated group; and 28.50±1.51 in more than college graduated group; p<.001). The optimal cut-off points were 24/25 for 60~69 years old group, 21/22 for 70~79 years old group, 17/18 for 80~84 years old group, and 13/14 for 85~89 years old group. The optimal cut-off points were 15/16 for individuals who were illiterate, 22/23 for individuals with 6 years of education, 22/24 for individuals with 9 years of education, and 26/27 for individuals with 12 or more years of education. Conclusions : This study presents normative data and cut-off points for the MoCA-K in older Korean adults. This data will facilitate more accurate detection and follow-up of the risk of mild cognitive impairment in this population, taking into consideration age and education. Future studies are required that should focus on the cut-off score on the level of education according to age.

• Ocean and Polar Research
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• v.44 no.2
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• pp.147-160
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• 2022

SRFC (Sub-Regional Fisheries Commission) requested to the ITLOS (International Tribunal for the Law of the Sea) an advisory opinion relating to the IUU (Illegl, Unreported, and Unregulated) fishing (Case No-21 of the ITLOS). Since, in the UNCLOS, there is no article authorizing the jurisdiction of the ITLOS full court's Advisory opinion, so various scholarly opinion wad divided. But ITLOS delivered its Advisory opinion confirming its jurisdictional competence over the Advisory proceedings with its legal opinion about the IUU issues. It opens new possibility of the alternative dispute settlement mechanism of the ITLOS through the advisory procedures. In reality, there has been a view that ICJ (International Court of Justice) could take the part of a kind of dispute settlement through its Advisory procedures. But the advisory procedures of the ITLOS, with no definite clause in UNCLOS about the advisory procedures, which provides more allowances for the function of advisory opinion as the alternative dispute settlement mechanism. ITLOS accepted the requests of the advisory opinion by the State parties through international organization or themselves directly. And the advisory opinion of the ITLOS aims the interpretation and application into the special issues-specially IUU fishing in Case No. 21 of the ITLOS-. Those factors could enable more enhanced role of the ITLOS as an alternative dispute settlement mechanism. But those possibility has contain risk of excessive and unlimited advisory role of the ITLOS. So it is important to focus on the restriction on the role of the State parties in the request of the advisory opinion to the ITLOS. In this regard it is meaningful that the ITLOS has suggested a kind of legal standing in the advisory procedures in that only coastal States could request the Advisory opinion about the IUU in their EEZ. Furthermore the discretionary power of the ITLOS in the Article 138 of the Rules of the Tribunal could curtail the abuse of the Advisory opinion initiated by the States parties of the UNCLOS. Under this framework, Advisory opinion could broaden more alternative option to the disputes between State parties of the UNCLOS in that after being delivered detailed interpretation of the UNCLOS about the specific issues, States parties could devote themselves to searching for flexible solution for the disputes between State parties. It could obtain legal explanation about the dispute under the Article 297 and Article 298 by detouring the jurisdiction limits through advisory procedures.