• Title/Summary/Keyword: Risk function

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Safety Evaluation on Real Time Operating Systems for Safety-Critical Systems (안전필수(Safety-Critical) 시스템의 실시간 운영체제에 대한 안전성 평가)

  • Kang, Young-Doo;Chong, Kil-To
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.10
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    • pp.3885-3892
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    • 2010
  • Safety-Critical systems, such as Plant Protection Systems in nuclear power plant, plays a key role that the facilities can be operated without undue risk to the health and safety of public and environment, and those systems shall be designed, fabricated, installed, and tested to quality standards commensurate with the importance of the functions to be performed. Computer-based Instrumentation and Control Systems to perform the safety-critical function have Real Time Operating Systems to control and monitoring the sub-system and executing the application software. The safety-critical Real Time Operating Systems shall be designed, analyzed, tested and evaluated to have capability to maintain a high integrity and quality. However, local nuclear power plants have applied the real time operating systems on safety critical systems through Commercial Grade Item Dedication method, and this is the reason of lack of detailed methodology on assessing the safety of real time operating systems, expecially to the new developed one. This paper presents the methodology and experiences of safety evaluation on safety-critical Real Time Operating Systems based upon design requirements. This paper may useful to develop and evaluate the safety-critical Real Time Operating Systems in other industry to ensure the safety of public and environment.

Effect of $\alpha$-Linolenic Acid Rich Perilla oil on Colonic Mucosal Levels of Biomarkers(Fatty Acid Profile, DAG, Eicosanoid) in Colon Carcinogenesis of DMH-Treated Rats (들기름이 Dimethylhydrazine으로 처리한 쥐에서 대장암의 Biomarker인 지방산조성과 1, 2-Diacylglycerol 및 Eicosanoid 함량에 미치는 영향)

  • 김채종
    • Journal of Nutrition and Health
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    • v.29 no.1
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    • pp.112-121
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    • 1996
  • The study was designed to observe the effect of blend fat calculated from the foods consumed in Korean with those of perilla oil, beef tallow and corn oil on colonic mucosal phospholipid fatty acid composition and the levels of TXB2 and diacylglycerol (DAG) which were known as biomarkers for cancer. Male Sprague Dawley rats, at 7 weeks of age, were divided into control and 1, 2-dimethylhydrazine (DMH)-treated group, and each group was subdivided into four groups. The experimental diets contained one of four dietary fats, blend fat (BF), perilla oil(PO), beef tallow (BT) or corn oil (CO), at 15% (w/w) level. At the same time, each rat was injected with saline for control group or DMH twice a week for 6 weeks to give total dose of 180mg/kg body weight. DMH injection, regardless of the type of dietary fats, significantly increased the levels of PGE2 and TXB2 in colonic mucosal layer compared to control (p<0.01). However, the level of eicosanoids was influenced by the types of dietary fats in both control and DMH group. In control groups, colonic mucosal level of TXB2 was higher in beef tallow group, but lower in perilla oil group compared to that of blend fat (p<0.01). In DMH groups, the level of TXB2 was higher in beef tallow and corn oil groups(p<0.05). The level of PGE2 showed the same trends with TXB2 and beef tallow most significantly increased the level of PGE2. DMH treatment did not influence on tissue fatty acid profile, which was directly reflected by dietary fatty acid composition. Proportions of C18 : 2 in colonic mucosal phospholipid well reflected dietary level of C18 : 2 showing the order CO>BF>PO>BT. The precentage of arachidonic acid(AA) in mucosal phospholipid was the highest by CO adn BT groups and the lowest by PO group. The incorporation of $\alpha$-linolenic acid in colonic mucosal phospholipid in perilla oil group was negatively correlated to the content of AA. Dietary level of C18 : 2 might not be the only controlling factor for the production of eicosanoids in colonic mucosa layer and might function with $\omega$3 fatty acids. The level of DAG was significanlty lower in PO group than that of BT group. Therefore, $\omega$3 $\alpha$-linolenic acid rich perilla oil could be very important dietary sourec in controlling eicosanoid production DAG level in cloln and recommenced to use more often in meal preparation to reduce the risk factor against colon cancer.

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Study on the Health Status of the Residents near Military Airbases in Pyeongtaek City (평택시 군용비행장 주변지역 주민건강조사)

  • Kim, Hyun-Joo;Roh, Sang-Chul;Kwon, Ho-Jang;Paik, Ki-Chung;Rhee, Moo-Yong;Jeong, Jae-Yun;Lim, Myung-Ho;Koo, Mi-Jin;Kim, Chang-Hoon;Kim, Hae-Young;Lim, Jeong-Hun;Kim, Dong-Hyun
    • Journal of Preventive Medicine and Public Health
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    • v.41 no.5
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    • pp.307-314
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    • 2008
  • Objectives : We conducted an epidemiologic survey to evaluate the effect of the aircraft noise exposure on the health of the residents near the military airbases in Pyeongtaek City. Methods : The evaluation of environmental noise level, questionnaire survey, and health examination were performed for 917 residents. The study population consisted of four groups: subjects who lived in the village close to the fighter airbase (high exposure), subjects who lived along the course of fighters (intermediate exposure), and subjects near a helicopter airbase, and the control group. Results : The prevalence of the aircraft noise related accident and irritable bowel syndrome in the exposure groups were higher than that of the control group. The risks of noise induced hearing loss, hypertension and diabetes mellitus were higher in the exposed groups than in the control group. The prevalence of anxiety disorder and primary insomnia were higher in the exposed groups than in the control group. Prevalence odd ratios of the risk for primary insomnia after adjusting age, sex, agricultural noise, and occupation were 4.03 [95% confidence interval (95% Cl) 1.56-10.47] for the subject near the helicopter airbase, 1.23 (95% Cl 0.40-3.76) for those intermediately exposed to fighter noise, and 4.99 (95% Cl 2.14-11.64) for those highly exposed to fighter noise. Conclusions : The results of the present study suggest that the aircraft noise may have adverse effects on hearing function, cardiovascular health and mental health. Therefore, it seems to be needed to take proper measures including the control of the aircraft noise and the management of the exposed people's health.

Establishment of location-base service(LBS) disaster risk prediction system in deteriorated areas (위치기반(LBS) 쇠퇴지역 재난재해 위험성 예측 시스템 구축)

  • Byun, Sung-Jun;Cho, Yong Han;Choi, Sang Keun;Jo, Bong Rae;Lee, Gun Won;Min, Byung-Hak
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.11
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    • pp.570-576
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    • 2020
  • This study uses beacons and smartphone Global Positioning System (GPS) receivers to establish a location-based disaster/hazard prediction system. Beacons are usually installed indoors to locate users using triangulation in the room, but this study is differentiated from previous studies because the system is used outdoors to collect information on registration location and temperature and humidity in hazardous areas. In addition, since it is installed outdoors, waterproof, dehumidifying, and dustproof functions in the beacons themselves are required, and in case of heat and humidity, the sensor must be exposed to the outside, so the waterproof function is supplemented with a separate container. Based on these functions, information on declining and vulnerable areas is identified in real time, and temperature/humidity information is collected. We also propose a system that provides weather and fine-dust information for the area concerned. User location data are acquired through beacons and smartphone GPS receivers, and when users transmit from declining or vulnerable areas, they can establish the data to identify dangerous areas. In addition, temperature/humidity data in a microspace can be collected and utilized to build data to cope with climate change. Data can be used to identify specific areas of decline in a microspace, and various analyses can be made through the accumulated data.

A Study of Power Law Distribution of Korean Disaster and Identification of Focusing Events (한국 재난의 멱함수분포와 사회적 충격사건에 관한 연구)

  • Kim, Yongkyun;Kim, Sang Pil;Cho, Hyoung-Sig;Sohn, Hong-Gyoo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.36 no.1
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    • pp.181-190
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    • 2016
  • Improvements in disaster management has become a global necessity because the magnitude of disasters is intensifying in parallel with the increased disaster damage. The disaster risk in Korea is also increasing due to the emergence of new types of disaster; such as the Middle East respiratory syndrome coronavirus, the increase of complex disasters, and the heightened probability of a catastrophic event due to climate change. This paper aimed to identify the disaster loss-frequency relationship from 1948 to 2014 in Korea by using four types of variables. In addition, this paper found major disasters that resulted in the reformation of disaster response organizations, and inputted the deaths and economic loss attributed to those disasters into the disaster loss-frequency graph. The research result substantiated that the disaster loss-frequency relationship in Korea follows the Power Law and found the coefficients of each Power Function. Additionally, this paper found that most of the reformations of disaster response organizations happened after major disasters that concentrated societies attention and anger due to the high human and economic impact; such events are labelled as "focusing events." These focusing events, with the characteristics of a low probability and high impact, are located in the long tail of the Power Law Distribution. This paper suggests that the effective public policy for disaster response needs to be developed by paying attention to 'low probability and high impact' focusing events that are located in the long tail of the Power Law Distribution.

A Study on the Method of Health Promotion in Korean Medicine: Correlation between Night-shift Work and Yin-deficiency (건강증진을 위한 한의학적 방법론 연구 -야간근로와 음허증의 상관관계를 중심으로-)

  • Lee Sang Jae;Park Jong Bae;Lee Sun Dong;Kim Kwang Ho
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.2
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    • pp.344-348
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    • 2004
  • This study regarded irregular life styles such as nigh-shifts as contrary to the norm advised in the rules of Yang-saeng to analyze the problems brought about in relation to the concept of 'Yin-deficiency syndrome'. Yin-deficiency survey was given to sales workers on a big shopping mall in Seoul to compare the measurements of daytime workers to those of nigh-shift workers. The measurement of complaining symptoms related to Yin-deficiency of daytime workers and night-shift workers were compared, In comparison of the daytime workers and the night-shift workers, night-shift workers showed higher measurements than the daytime workers in the item of irritable fever on the five Hearts, flushing of the zygomatic region in the afternoon, tidal fever, dizziness, insomnia, yellow and scanty urination, and constipation. Especially tidal fever, insomnia, and constipation showed statistically significant difference. The total of ten items consisting of Yin-deficiency-related symptoms showed statistically significant high score in night-shift workers than the daytime workers. 'Factors for deficiency-type Heat' consisting of irritable fever on the five Hearts, flushing of the zygomatic region in the afternoon, tidal fever, and dried mouth and throat showed statistically significant high score in night-shift workers than the daytime workers. 'Accompanying factors' consisting of night sweats, emaciation, dizziness, insomnia, yellowish and scanty urination, and constipation also showed statistically and significantly high score in night-shift workers than the daytime workers. From the above results that night-shift workers show high degree of Yin-deficiency than daytime workers, and those overworking irregularly also show high degree of Yin-deficiency than those who work for adequate amount of time regularly implies that sitting up at night for work and sleeping at daytime, excessive work, and irregular life styles all function as high-risk factor for Yin-deficiency.

Agro-climate Characteristics and Stability in Crop Production of Daegwallyeong Area in Korea (기상자료 분석을 통한 대관령 지역의 작물 최저 한계온도일 추정)

  • Ryu, Jong-Soo;Lee, Jeong-Tae;Lee, Gye-Jun;Oh, Dong-Shig
    • Korean Journal of Soil Science and Fertilizer
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    • v.45 no.6
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    • pp.1153-1156
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    • 2012
  • Daegwallyeong area to be formed along the mountainous terrain more above 800 m of sea level is known as the cold zone to occur frequently wind, rain and fog. This study to evaluate the stability of crop production and agricultural production potential in the Daegwallyeong was calculated for the low temperature frequency of occurrence and potential evapotranspiration changes with announce the release of Korea Meteorological Administration (KMA) from 1972 to 2009 up to 38 years. Evapotranspiration calculated FAO and other international standard method authorized under the PENMAN-MONTEITH Method was used, and the low temperature onset and frequency of the Gumbel probability density function was used. As a result, the variation of day evaporation for 38 years were showed to respectively width of variation from maximum $9mm\;day^{-1}$ to minimum $0.5mm\;day^{-1}$. The frequency of reappearance to first emergence day that lasts more than 5 days with temperature $5^{\circ}C$ over is 3 April a 50-year frequency, 10 April a 25-year frequency, 20 April a 10-year frequency, 28 April a 5-year frequency, 8 May a 2-year frequency. Psychrotrophic crop to growth temperature more than $5^{\circ}C$ can be secured to stable production with planting after May 8, prior to planting for normal growth can be seen that the risk of growth.

Surgical Treatment of Bullous Emphysema with Giant Bullae (거대 기포성 폐기종의 외과적 치료)

  • Jang, Jae-Han;Kim, Min-Ho;Kim, Gong-Su
    • Journal of Chest Surgery
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    • v.29 no.4
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    • pp.408-413
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    • 1996
  • In most cases of diffuse bullous emphysema and chronic obstructive lung disease, t e risk of surgical treatment is very high. But surgical treatment in selected cases of bullous emphysema with localized involvement of only one side of the lung has suggested safe and good management. So patient selection of surgical treatment Is one of the most important things in management of bullous emphysema. From 1987 to 1992, 11 patients were operated for bullous emphysema with giant bullae at the Department of Thoracic and Cardiovascular Surgery of Chonbuk National University Hospital. Author selected surgical candidates who had progressive dyspnea and symptomatic bullae occupying more than one third of the hemithorax and shifting the trachea and mediastinum to the opposite side of the lung. There were 7 males and 4 females ranged from 19 to 61 years of age. Operative procedures were bullectomy and/or wedge resection in 7 cases, segmentectomy in 2 cases and lobectomy in 2 cases. Symptoms and pulmonary function of all patients were improved six months to three years postoperat vely. There were no postoperative death. We conclude that surgical treatment of bullous emphysema with giant bullae is safe and a good treatment of modality in indicated patients.

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Optimization of Multi-reservoir Operation considering Water Demand Uncertainty in the Han River Basin (수요의 불확실성을 고려한 한강수계 댐 연계 운영 최적화)

  • Chung, Gun-Hui;Ryu, Gwan-Hyeong;Kim, Joong-Hoon
    • Journal of the Korean Society of Hazard Mitigation
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    • v.10 no.1
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    • pp.89-102
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    • 2010
  • Future uncertainty on water demand caused by future climate condition and water consumption leads a difficulty to determine the reservoir operation rule for supplying sufficient water to users. It is, thus, important to operate reservoirs not only for distributing enough water to users using the limited water resources but also for preventing floods and drought under the unknown future condition. In this study, the reservoir storage is determined in the first stage when future condition is unknown, and then, water distribution to users and river stream is optimized using the available water resources from the first stage decision using 2-stage stochastic linear programming (2-SLP). The objective function is to minimize the difference between target and actual water storage in reservoirs and the water shortage in users and river stream. Hedging rule defined by a precaution against severe drought by restricting outflow when reservoir storage decreases below a target, is also applied in the reservoir operation rule for improving the model applicability to the real system. The developed model is applied in a system with five reservoirs in the Han River basin, Korea to optimize the multi-reservoir system under various future water demand scenarios. Three multi-purposed dams - Chungju, Hoengseong, and Soyanggang - are considered in the model. Gwangdong and Hwacheon dams are also considered in the system due to the large capacity of the reservoirs, but they are primarily for water supply and power generation, respectively. As a result, the water demand of users and river stream are satisfied in most cases. The reservoirs are operated successfully to store enough water during the wet season for preparing the coming drought and also for reducing downstream flood risk. The developed model can provide an effective guideline of multi-reservoir operation rules in the basin.

The Role of Serum Thyrotropin Level as a Meaningful Predictor of Papillary Thyroid Cancer in Patients with Nontoxic Nodular Goiter (정상기능 갑상선 결절 환자에서 갑상선 유두암의 의미 있는 예측인자로서 혈청 갑상선 자극호르몬의 역할)

  • Moon, Shin-Je;Park, Jung-Hwan;Lee, Yu-Hwa;Hong, Sang-Mo;Lee, Chang-Bum;Park, Yong-Soo;Kim, Dong-Sun;Choi, Woong-Hwan;Ahn, You-Hern
    • Korean Journal of Head & Neck Oncology
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    • v.27 no.2
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    • pp.198-203
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    • 2011
  • Background and Objectives : Distinguishing benign from malignant lesion in thyroid noddex is important but clinically difficult. FNAB is the first investigation of choice. However, cytologic results are often indeterminable. In those cases, additional molecular biologic tests are helpful. If serologic tests are available to predict malignancy, it can be useful to fortify accurate diagnosis. We analyzed whether TSH or FreeT4 level could be used as a predictor of malignancy. Materials and Methods : From January 2008 to March 2009, 540 patients received one of thyroidectomy in a single center. We only included 167 patients from 18 to 65 years old without cardiopulmonary or renal disorders. All the patients were in euthyroid state and took no medications, which affect the thyroid function. We reviewed charts retrospectively to find out differences in TSH level and FreeT4 level between the benign and malignant groups. Results : In this study, all the patients with malignancy had the papillary cancer. In benign group, average TSH level came out to be 1.48mU/L, whereas the average TSH level of malignant group was 1.98 mU/L. Moreover, the higher the cancer stage was, the higher the TSH level was. Although we have adjusted factors that can affect TSH level(age, sex, race, goiter type), we still received the same result. The risk of malignant cancer increased in proportion with TSH level within the normal range. In free T4 level, there was no difference between benign and malignant group. Conclusion : We propose that TSH level can play a role as one of the predictors for thyroid cancer. However, there is limitation because all the patients with malignancy in this study have papillary cancer. Thus, we can apply this result only in papillary cancer, and we need more study for other types of thyroid cancer.