• The Korean Journal of Nuclear Medicine
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• v.38 no.5
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• pp.331-337
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• 2004

Cardiac neurotransmission imaging allows in vivo assessment of presynaptic reuptake, neurotransmitter storage and postsynaptic receptors. Among the various neurotransmitter, I-123 MIBG is most available and relatively well-established. Metaiodobenzylguanidine (MIBG) is an analogue of the false neurotransmitter guanethidine. It is taken up to adrenergic neurons by uptake-1 mechanism as same as norepinephrine. As tagged with I-123, it can be used to image sympathetic function in various organs including heart with planar or SPECT techniques. I-123 MIBG imaging has a unique advantage to evaluate myocardial neuronal activity in which the heart has no significant structural abnormality or even no functional derangement measured with other conventional examination. In patients with cardiomyopathy and heart failure, this imaging has most sensitive technique to predict prognosis and treatment response of betablocker or ACE inhibitor. In diabetic patients, it allow very early detection of autonomic neuropathy. In patients with dangerous arrhythmia such as ventricular tachycardia or fibrillation, MIBG imaging may be only an abnormal result among various exams. In patients with ischemic heart disease, sympathetic derangement may be used as the method of risk stratification. In heart transplanted patients, sympathetic reinnervation is well evaluated. Adriamycin-induced cardiotoxicity is detected earlier than ventricular dysfunction with sympathetic dysfunction. Neurodegenerative disorder such as Parkinson's disease or dementia with Lewy bodies has also cardiac sympathetic dysfunction. Noninvasive assessment of cardiac sympathetic nerve activity with I-123 MIBG imaging nay be improve understanding of the pathophysiology of cardiac disease and make a contribution to predict survival and therapy efficacy.

• Proceedings of the Korea Water Resources Association Conference
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• 2019.05a
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• pp.150-150
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• 2019

The development of prolong and severe drought can directly impact on the environment, agriculture, economics and society of country. A lot of efforts have been made across worldwide in the planning, monitoring and mitigation of drought. Currently, different drought indices such as the Palmer Drought Severity Index (PDSI), Standardized Precipitation Index (SPI), Standardized Precipitation Evapotranspiration Index (SPEI) are developed and most commonly used to monitor drought characteristics quantitatively. However, it will be very meaningful and essential to develop a more effective technique for assessment and monitoring of onset and end of drought. Therefore, in this study, the hidden Markov Bayesian classifier (MBC) was employed for the assessment of onset and end of meteorological drought classes. The results showed that the probabilities of different classes based on the MBC were quite suitable and can be employed to estimate onset and end of each class for meteorological droughts. The classification results of MBC were compared with SPI and with past studies which proved that the MBC was able to account accuracy in determining the accurate drought classes. For more performance evaluation of classification results confusion matrix was used to find accuracy and precision in predicting the classes and their results are also appropriate. The overall results indicate that the MBC was effective in predicating the onset and end of drought events and can utilized for monitoring and management of short-term drought risk.

• Journal of Navigation and Port Research
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• v.43 no.1
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• pp.57-63
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• 2019

It is time to study safety improvement on container terminals to maintain a high-quality service to customers' productivity and safety. The data analyzed was of the past 3 years accidents data from a container terminal in the Busan port. I especially tried to found out the equipment that had the highest number of accidents and what the main causes were. This study suggests the top hazards identified in the container terminal using risk assessment, Moreover, it seeks control measurements to prevent hazards by bowtie methodology.

• Journal of the Korean Academy of Esthetic Dentistry
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• v.16 no.2
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• pp.7-18
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• 2007

There is now an increased demand for harmony between the peri-implant gingiva and adjacent dentition. In the event of a pending loss of a single tooth in the aesthetic zone with healthy periodontium, expectation for optimal gingival and prosthodontic aesthetics are often very high. Unfortunately, bone resorption is common following the removal of an anterior tooth, compromising the gingival tissue levels for the eventual implant restoration. Also, improper implant placement and inadequate osseous-gingival support potentially deleterious aesthetic result. The creation of an esthetic implant restoration with gingival architecture that harmonizes with the adjacent dentitionis formidable challenge. The predictability of the peri-implant esthetic outcome may ultimately be determined by the patient's own presenting anatomy rather than the clinician's ability to manage state-of-the-art procedures. To more accurately predict the peri-implant esthetic outcome before removing a failing tooth, a considering of diagnostic keys is essential. This presentation addresses the useful diagnostic keys that affect the predictability of peri-implant gingival aesthetics and the overcoming of the risk factors in anterior single-tooth replacement; it also describes a surgical and prosthodontic technique in achieving a long term successful esthetic outcome. Proper diagnosis and understanding of the biological and periodontal variables of failing dentition and their response to surgical and prosthodontic procedures are the essence of predictability. Using a smart protocol that alters the periodontium toward less risk and more favorable assessment of the diagnostic keys before implant placement will provide the most predictable esthetic outcome. Simple diagnostic keys suggested this presentation are useful method to evaluate the overcoming of the risk factors in anterior single implant restoration.

• Journal of the Korean Society of Safety
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• v.37 no.4
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• pp.129-138
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• 2022

A new method for injecting cooling water into the Korean research reactor (KRR) in the event of beam tube rupture is proposed in this paper. Moreover, the research evaluates the risk to the reactor core in terms of core damage frequency (CDF). The proposed method maintains the cooling water in the chimney at a certain level in the tank to prevent nuclear fuel damage solely by gravitational coolant feeding from the emergency water supply system (EWSS). This technique does not require sump recirculation operations described in the current procedure for resolving beam tube accidents. The reduction in the risk to the core in the event of beam tube rupture that can be achieved by the proposed change in the cooling water injection design is quantified as follows. 1) The total CDF of the KRR for the proposed design change is approximately 4.17E-06/yr, which is 8.4% lower than the CDF of the current design (4.55E-06/yr). 2) The CDF for beam tube rupture is 7.10E-08/yr, which represents an 84.1% decrease compared with that of the current design (4.49E-07/yr). In addition to this quantitative reduction in risk, the modified cooling water injection design maintains a supply of pure coolant to the EWSS tank. This means that the reactor does not require decontamination after an accident. Thermal hydraulic analysis proves that the water level in the reactor pool does not cause damage to the nuclear fuel cladding after beam tube rupture. This is because the amount of water in the chimney can be regulated by the EWSS function. The EWSS supplies emergency water to the reactor core to compensate for the evaporation of coolant in the core, thus allowing water to cover the fuel assemblies in the reactor core over a sufficient amount of time.

• The Journal of Engineering Geology
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• v.28 no.3
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• pp.379-395
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• 2018

A walking trail environment can be divided into the upper part of the trail, the trail itself, and the lower part of the trail. In this study, based on field investigations, we developed a risk index for trails by considering human/societal factors that affect each of these three trail environments. A checklist was developed for field investigations, and checklist items were scored through relative importance analysis. The relative weights of items were analyzed using the AHP (Analytic Hierarchy Process) technique, revealing that the upper environment of a trail is twice as important as the rest of the environment. The importance and score of items belonging to each environment were determined. We define the risk index as the sum of the item scores. Weights were added using data from existing investigations including landslides risk rating and designated risk steep slopes. The risk index has a maximum value of 200, and the maximum and minimum calculated scores of 335 risk sections were 159 and 64.2, respectively. As a result of comparative analysis between field observations and risk index calculations, most sections at relatively low risk had risk values less than 100, and sections with high risks or that had been the site of accident yielded scores that exceeded 140.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.36 no.5
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• pp.553-562
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• 2012

Computational Fluid Dynamics (CFD) analysis has been performed to estimate the air temperature inside an Auxiliary Feed Water (AFW) Motor-Driven (MD) pump room for the case where there is loss of Heating, Ventilation, and Air-Conditioning (HVAC). A transient calculation for the closed pump room without cooling by any HVAC system shows that the volume-averaged air temperature reaches around $60^{\circ}C$ for a transient period of 8.0 h. From previous studies, the external air and surface boundary temperatures are assumed to increase slowly starting from an initial temperature of $35^{\circ}C$. For the cases where the door is opened at 2, 4, and 6 h after the initiation of HVAC failure, the average air temperature promptly drops by about $4^{\circ}C$ when the door is opened and then slowly increases. The current calculations based on the CFD technique predict the rate of increase of air temperature to be lower than that determined by previous conservative calculations on the basis of a lumped model.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.707-712
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• 2014

Purpose: Anastomotic leakage (AL) is associated with high morbidity and mortality, high reoperation rates, and increased hospital length of stay. Here we investigated the risk factors for AL after anterior resection for rectal cancer with a double stapling technique. Patients and Methods: Data for 460 patients who underwent primary anterior resection with a double stapling technique for rectal carcinoma at a single institution from 2003 to 2007 were prospectively collected. All patients experienced a total mesorectal excision (TME) operation. Clinical AL was defined as the presence of leakage signs and confirmed by diagnostic work-up according to ICD-9 codes 997.4, 567.22 (abdominopelvic abscess), and 569.81 (fistula of the intestine). Univariate and logistic regression analyses of 20 variables were undertaken to determine risk factors for AL. Survival was analysed using the Cox regression method. Results: AL was noted in 35 (7.6%) of 460 patients with rectal cancer. :Median age of the patients was 65 (50-74) and 161 (35%) were male. The diagnosis of AL was made between the 6th and 12th postoperative day (POD; mean 8th POD). After univariate and multivariate analysis, age (p=0.004), gender (p=0.007), tumor site (p<0.001), preoperative body mass index (EMI) (p<0.001), the reduction of TSGF on 5th POD less than 10U/ml (p=0.044) and the pH value of pelvic dranage less than or equal to 6.978 on 3rd POD (p<0.001) were selected as 6 independent risk factors for AL. It was shown that significant differences in survival of the patients were AL-related (p<0.001), high ASA score related (p=0.036), high-level EMI related (p=0.007) and advanced TNM stage related

• Archives of Plastic Surgery
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• v.49 no.1
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• pp.43-49
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• 2022

Background Cleft lip and cleft palate are the most frequent congenital craniofacial deformities, with an incidence of approximately 1 per 700 people. Postoperative palatal fistula is one of the most significant long-term complications. This study investigated the incidence of postoperative palatal fistula and its predictive factors based on 25 years of experience at our hospital. Methods We retrospectively reviewed 636 consecutive palatal repairs performed between January 1996 and October 2020 by a single surgeon. Data from patients' medical records regarding cleft palate repair were analyzed. The preoperative extent of the cleft was evaluated using the Veau classification system, and the cleft palate repair technique was chosen according to the extent of the cleft. SPSS version 25.0 was used for all statistical analyses, and exploratory univariate associations were investigated using the t-test. Results Fistulas occurred in 20 of the 636 patients; thus, the incidence of palatal fistula was 3.1%. The most common fistula location was the hard palate (9/20, 45%), followed by the junction of the hard and soft palate (6/20, 30%) and the soft palate (5/20, 25%). The cleft palate repair technique significantly predicted the incidence of palatal fistula following cleft palate repair (P=0.042). Fistula incidence was significantly higher in patients who underwent surgery using the Furlow double-opposing Z-plasty technique (12.1%) than in cases where the Busan modification (3.0%) or two-flap technique (2.0%) was used. Conclusions The overall incidence of palatal fistulas was 3.1% in this study. Moreover, the technique of cleft palate repair predicted fistula incidence.

• Journal of Soil and Groundwater Environment
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• v.22 no.6
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• pp.1-11
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• 2017

This study was conducted to investigate the performance of four commercial chemical agents in stabilizing arsenic (As) in soil at the forest area near the former Janghang smelter site. After amending the stabilizing agents (A, B, C, and D) into As-contaminated soil samples, synthetic precipitation leaching procedure (SPLP) and solubility bioavailability research consortium (SBRC)-extractable As concentrations significantly decreased except for agent D, which is mainly composed of fly ash and calcium carbonate. Increase of SPLP and SBRC-extractable As concentrations in four soil samples (S1, S2, S3, and J2) was attributed to desorption of As adsorbed on iron oxides due to high pH generated by agent D. It is therefore necessary to consider application conditions according to soil characteristics such as pH and buffering capacity. Results of sequential extraction showed that readily extractable fractions of As in soil (i.e., sum of $SO_4-$ and $PO_4-extractable$ As in soil) were converted into non-readily extractable fractions by amending agents A, B, and C. Such changes in the As distribution in soil resulted in the decrease of SPLP and SBRC-extractable As concentration. A series of follow-up monitoring and management plan has been suggested to assess the longevity of the stabilization treatments in the site.