• 제목/요약/키워드: Risk Weight

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Outcomes after repair of complete atrioventricular canal with a modified single-patch technique: a retrospective study

  • George Samanidis;Konstantinos Kostopanagiotou;Meletios Kanakis;Georgios Kourelis;Kyriaki Kolovou;Georgios Vagenakis;Dimitrios Bobos;Nicholas Giannopoulos
    • Journal of Yeungnam Medical Science
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    • 제40권2호
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    • pp.187-192
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    • 2023
  • Background: This study aimed to present the short- and midterm outcomes after complete atrioventricular canal defect (CAVC) repair using a single-patch technique. Methods: This study included 30 children who underwent surgical correction of the CAVC using a single-patch technique. Results: The median age of the patients was 5.7 months (interquartile range [IQR], 5.0-7.5 months), and 23 patients (76.7%) had type A CAVC. Fourteen patients (46.7%) were female and 17 (56.7%) had been diagnosed with Down syndrome. The in-hospital mortality rate was 0%. No deaths were observed during a median follow-up of 4 years (IQR, 3.5-5.0 years). Patients without Down syndrome were associated with late moderate mitral regurgitation (MR) (p=0.02). Late MR less than moderate degree was observed in 96.6%, 78.5%, and 50% of patients after 2, 4, and 5 years of follow-up, respectively, while late tricuspid valve regurgitation less than moderate degree was observed in 96.7%, 85.9%, and 59.0% of patients after 2, 4, and 6 years of follow-up, respectively. After a median follow-up of 4 years, only one patient had required surgical repair of a left ventricular outflow tract obstruction, which occurred 26 months after the first operation. Multivariable logistic regression analysis adjusted for the type of CAVC, sex, Down syndrome, age, and weight revealed that the absence of Down syndrome was a risk factor for late moderate MR (MR-2) (odds ratio, 0.05; 95% confidence interval, 0.006-0.50; p=0.01). Conclusion: A single-patch technique for CAVC surgical repair is a safe method with acceptable short- and midterm results.

활성화 함수 근사를 통한 지수함수 기반 신경망 마스킹 기법 (Masking Exponential-Based Neural Network via Approximated Activation Function)

  • 김준섭;김규상;박동준;박수진;김희석;홍석희
    • 정보보호학회논문지
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    • 제33권5호
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    • pp.761-773
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    • 2023
  • 본 논문에서는 딥러닝 분야에서 사용되는 신경망 모델, 그중에서도 다중 계층 퍼셉트론 모델에 사용되는 지수함수 기반의 활성화 함수를 근사 함수로 대체하고, 근사 함수에 마스킹을 적용함으로써 신경망 모델의 추론 과정의 전력 분석 저항성을 높이는 방법을 제안한다. 이미 학습된 값을 사용하여 연산하는 인공 신경망의 추론 과정은 그 특성상 가중치나 편향 등의 내부 정보가 부채널 공격에 노출될 위험성이 있다. 다만 신경망 모델의 활성화 함수 계층에서는 매우 다양한 함수를 사용하고, 특히 지수함수 기반의 활성화 함수에는 마스킹 기법 등 통상적인 부채널 대응기법을 적용하기가 어렵다. 따라서 본 연구에서는 지수함수 기반의 활성화 함수를 단순한 형태로 근사하여도 모델의 치명적인 성능 저하가 일어나지 않음을 보이고, 근사 함수에 마스킹을 적용함으로써 전력 분석으로부터 안전한 순방향 신경망 모델을 제안하고자 한다.

Effect of Heavy Metal Resistant and Halotolerant Rhizobacterium Bacillus safensis KJW143 on Soybean under Salinty and Cadmium Exposure

  • Eun-Hae Kwon;Ho-Jun Gam;Yosep Kang;Jin-Ryeol Jeon;Ji-In Woo;Sang-Mo Kang;In-Jung Lee
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2023년도 춘계학술대회
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    • pp.32-32
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    • 2023
  • Cadmium and salt exposure to crops is considered vulnerable for production as well as consumption. To address these challenges, the current study aimed to mitigate the toxicity induced by salt and cadmium in soybean plants through the application of bacterial strain Bacillus safensis KJW143 isolated from the rhizosphere of oriental melon..The bioassay analysis revealed that KJW143 is a highly salt-tolerant and cadmium-resistant (Cd) strain with an innate ability to produce melatonin, gibberellin (GA3), Indole-3-Acetic Acid (IAA), and organic acids (i.e., acetic, succinic, lactic, and propionic acids). Soybean plants at 20 days old were treated with KJW143 in a different form (pellet, broth, and together) and their effect on plant performance was investigated. Inoculation with KJW143enhanced plant biomass and growth attributes in soybean plants compared to the control (non-treated). In particular, we observed that only pellet-treated showed 65%, 27.5%, and 28.7% increase in growth (shoot fresh weight) compared to broth, broth with pellet, and control. In addition, bacterial strain KJW143 treatment (only pellet) modulated the physiochemical apparatus of soybean plants by increasing glucose (390%), arabinose (166%), citric acid (22.98%) and reducing hydrogen peroxide (29.7%), catalase (32.1%), salicylic acid (25.6%) compared to plants with combined stressed plants (cd and salinity). These findings suggest that bacterial strain KJW143 could be usedas a biofertilizer to minimize the probable risk of heavy metal and salinity stress on crops.

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Outcomes after Mechanical Aortic Valve Replacement in Children with Congenital Heart Disease

  • Joon Young Kim;Won Chul Cho;Dong-Hee Kim;Eun Seok Choi;Bo Sang Kwon;Tae-Jin Yun;Chun Soo Park
    • Journal of Chest Surgery
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    • 제56권6호
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    • pp.394-402
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    • 2023
  • Background: The optimal choice of valve substitute for aortic valve replacement (AVR) in pediatric patients remains a matter of debate. This study investigated the outcomes following AVR using mechanical prostheses in children. Methods: Forty-four patients younger than 15 years who underwent mechanical AVR from March 1990 through March 2023 were included. The outcomes of interest were death or transplantation, hemorrhagic or thromboembolic events, and reoperation after mechanical AVR. Adverse events included any death, transplant, aortic valve reoperation, and major thromboembolic or hemorrhagic event. Results: The median age and weight at AVR were 139 months and 32 kg, respectively. The median follow-up duration was 56 months. The most commonly used valve size was 21 mm (14 [31.8%]). There were 2 in-hospital deaths, 1 in-hospital transplant, and 1 late death. The overall survival rates at 1 and 10 years post-AVR were 92.9% and 90.0%, respectively. Aortic valve reoperation was required in 4 patients at a median of 70 months post-AVR. No major hemorrhagic or thromboembolic events occurred. The 5- and 10-year adverse event-free survival rates were 81.8% and 72.2%, respectively. In univariable analysis, younger age, longer cardiopulmonary bypass time, and smaller valve size were associated with adverse events. The cut-off values for age and prosthetic valve size to minimize the risk of adverse events were 71 months and 20 mm, respectively. Conclusion: Mechanical AVR could be performed safely in children. Younger age, longer cardiopulmonary bypass time and smaller valve size were associated with adverse events. Thromboembolic or hemorrhagic complications might rarely occur.

Image-based Soft Drink Type Classification and Dietary Assessment System Using Deep Convolutional Neural Network with Transfer Learning

  • Rubaiya Hafiz;Mohammad Reduanul Haque;Aniruddha Rakshit;Amina khatun;Mohammad Shorif Uddin
    • International Journal of Computer Science & Network Security
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    • 제24권2호
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    • pp.158-168
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    • 2024
  • There is hardly any person in modern times who has not taken soft drinks instead of drinking water. The rate of people taking soft drinks being surprisingly high, researchers around the world have cautioned from time to time that these drinks lead to weight gain, raise the risk of non-communicable diseases and so on. Therefore, in this work an image-based tool is developed to monitor the nutritional information of soft drinks by using deep convolutional neural network with transfer learning. At first, visual saliency, mean shift segmentation, thresholding and noise reduction technique, collectively known as 'pre-processing' are adopted to extract the location of drinks region. After removing backgrounds and segment out only the desired area from image, we impose Discrete Wavelength Transform (DWT) based resolution enhancement technique is applied to improve the quality of image. After that, transfer learning model is employed for the classification of drinks. Finally, nutrition value of each drink is estimated using Bag-of-Feature (BoF) based classification and Euclidean distance-based ratio calculation technique. To achieve this, a dataset is built with ten most consumed soft drinks in Bangladesh. These images were collected from imageNet dataset as well as internet and proposed method confirms that it has the ability to detect and recognize different types of drinks with an accuracy of 98.51%.

달리기 시 착지 유형에 따른 인체에 미치는 충격의 변화 (Changes in Impact Characteristics of the Body by Different Heel Strike Patterns during Running)

  • Young-Seong Lee;Sang-Kyoon Park
    • 한국운동역학회지
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    • 제33권4호
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    • pp.164-174
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    • 2023
  • Objective: The aim of this study was to quantitatively analyze the impact characteristics of the lower extremity on strike pattern during running. Method: 19 young subjects (age: 26.53 ± 5.24 yrs., height: 174.89 ± 4.75 cm, weight: 70.97 ± 5.97 kg) participated in this study. All subjects performed treadmill running with fore-foot strike (FFS), mid-foot strike (MFS), and rear-foot strike (RFS) to analyze the impact characteristics in the lower extremity. Impact variables were analyzed including vertical ground reaction force, lower extremity joint moments, impact acceleration, and impact shock. Accelerometers for measuring impact acceleration and impact shock were attached to the heel, distal tibia, proximal tibia, and 50% point of the femur. Results: The peak vertical force and loading rate in passive portion were significantly higher in MFS and FFS compared to FFS. The peak plantarflexion moment at the ankle joint was significantly higher in the FFS compared to the MFS and RFS, while the peak extension moment at the knee joint was significantly higher in the RFS compared to the MFS and FFS. The resultant impact acceleration was significantly higher in FFS and MFS than in RFS at the foot and distal tibia, and MFS was significantly higher than FFS at the proximal tibia. In impact shock, FFS and MFS were significantly higher than RFS at the foot, distal tibia, and proximal tibia. Conclusion: Running with 3 strike patterns (FFS, MFS, and RFS) show different impact characteristics which may lead to an increased risk of running-related injuries (RRI). However, through the results of this study, it is possible to understand the characteristics of impact on strike patterns, and to explore preventive measures for injuries. To reduce the incidence of RRI, it is crucial to first identify one's strike pattern and then seek appropriate alternatives (such as reducing impact force and strengthening relevant muscles) on that strike pattern.

The Hazardous Components and Prevailing Rate of Sarcopenic Obesity in Younger Women : Based on 2008-2011 Korean National Health and Nutrition Examination Surveys

  • Jongseok Hwang;Chang-Ryeol Lee
    • 대한통합의학회지
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    • 제12권2호
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    • pp.1-10
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    • 2024
  • Purpose : Sarcopenic obesity is associated with adverse health consequences in females. Nevertheless, there has been limited research on the hazardous components and prevailing rates of sarcopenic obesity among younger women. This study aimed to identify the hazardous components and prevailing rates of sarcopenic obesity in younger females. Methods : This study utilized data based on 2008~2011 from the Korea National Health and Nutrition Examination Surveys by the centers for disease control and prevention. The analysis was concentrated on a subset of 1,520 women aged between 30 and 39 years of age. The participants answered a questionnaire to gather demographic information. They then underwent a physical examination to measure the human detention variables, which was conducted utilizing bioelectrical impedance analysis. The blood pressure and blood laboratory tests were determined using established laboratory protocols for evaluating blood parameters. Results : This study included 1,520 patients aged 30~39 years old. The mean age of the participants was 34.97 (years)±2.74 and the overall prevailing rate was 1.84 %. The hazard components in human dimensions were the height, weight, body mass index (BMI), waist circumference (WC) and skeletal muscle mass index (SMI). The hazard components in biochemical and blood pressure were high fasting glucose, increased triglyceride, elevated total cholesterol, high systolic blood pressure, and increased diastolic blood pressure with p-values <.05. Conclusion : This study examined the hazardous components and prevailing rates of sarcopenic obesity in younger women living in the community. The results contribute to the current body of knowledge on sarcopenic obesity and shed light on possible hazardous components in a younger female population. Based on these findings, there should be increased health and medical attention towards the prevention, management, and health promotion related to reducing risk factors for sarcopenic obesity in younger women.

Asbestos Exposure and Ovarian Cancer: A Meta-analysis

  • Seo Young Kim;Ha Kyun Chang;Ohwi Kwon;JaeYoung Park;Jun-Pyo Myong
    • Safety and Health at Work
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    • 제15권1호
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    • pp.1-8
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    • 2024
  • Background: The International Agency for Research on Cancer (IARC) Monograph conducted a systematic review of the relationship between asbestos and ovarian cancer. However, there may have been information bias due to the undue weight given to few articles. To address this limitation, the present study performed a meta-analysis integrating studies published both before and after the 2012 IARC Monograph on Asbestos, with the aim of investigating the association between asbestos exposure and ovarian cancer. Methods: A comprehensive search of major journal databases was conducted to identify studies examining the relationship between asbestos exposure and ovarian cancer, including those featured in the 2012 IARC Monograph on Asbestos. A meta-analysis on asbestos exposure and cancer risk was performed. Results: The meta-analysis of studies published after the 2012 IARC Monograph on Asbestos found a summary Standardized Mortality Ratio (SMR) of 2.04 (95% CI: 1.03-4.05; p = 0.0123; 5 studies), with a significant degree of heterogeneity among the studies (I2 = 72.99%). The combined analysis of 15 studies before and after the 2012 IARC Monograph showed an overall summary SMR of 1.72 (95% CI: 1.43-2.06; p = 0.0349; 15 studies), with a moderate degree of heterogeneity (I2 = 42.99%). Conclusion: This meta-analysis provides evidence of a significant association between asbestos exposure and ovarian cancer mortality. While the possibility of misdiagnosis in earlier studies cannot be completely ruled out, recent findings suggest a robust correlation between asbestos exposure and ovarian cancer. This highlights the importance of sustained efforts to minimize asbestos exposure and protect public health.

Effects of Walking Activity Monitoring and Feedback Using Wearable Device on Body Composition and Metabolic Syndrome Risk Factors in Middle-aged Women

  • Chan-Yang Kim;Woo-Young Park
    • 한국컴퓨터정보학회논문지
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    • 제29권5호
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    • pp.101-110
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    • 2024
  • 이 연구의 목적은 웨어러블 디바이스를 활용한 걷기 활동에 대한 모니터링과 피드백이 중년 여성의 체성분 및 대사증후군 지표 변화에 미치는 영향을 분석하고자 실시하였다. 연구 대상자는 6개월간 모바일 연동 웨어러블 디바이스를 사용하였으며, 지원하는 모바일 앱을 통해 자동 전송된 보행 수 및 활동량 정보를 모니터링을 통해 피드백을 제공하였다. 연구 결과 체중, 골격근량, 그리고 체지방률에서 통계적으로 유의한 차이가 나타났다(p<.001). 대사증후군 지표 변화는 수축기 혈압(p<.05), 공복 혈당(p<.01), 복부둘레(p<.001)에서 유의한 차이가 나타났고, TC(p<.001)와 LDL-C(p<.05)에서 유의한 차이가 나타났다. 따라서 쉽고 편리하게 적용 가능한 웨어러블 디바이스는 좌업적인 생활습관을 가진자들의 신체활동량 증가와 대사증후군 예방을 위한 효과적인 도구로 볼 수 있다.

Effects of Continuous Nutrition Care on Nutritional Status and Dietary Habits of Patients With Colorectal Cancer Receiving Adjuvant Chemotherapy After Surgery

  • Jina Son;Ha I Kang;Eun young Jung;Hae won Ryu;Kyung-Ha Lee
    • Clinical Nutrition Research
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    • 제12권2호
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    • pp.99-115
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    • 2023
  • Patients with colorectal cancer may experience symptoms such as diarrhea, nausea, and anorexia, during surgery and chemotherapy, which can increase the risk of malnutrition. In addition, dietary habits play a key role in the onset of colorectal cancer; therefore, it is necessary to improve dietary habits to prevent recurrence during treatment after diagnosis. In this study, a clinical nutritionist conducted 4 interviews for patients diagnosed with colorectal cancer and scheduled for colectomy: before surgery, after surgery, 1st chemotherapy, and 2nd chemotherapy, and provided nutrition care for each treatment course to determine its effects on nutrition status and disease prognosis. Significant weight loss but no decrease in muscle mass was observed during treatment. Body fat mass, although not statistically significant, showed a decreasing tendency. The percentage of people who responded 'yes' to the below items increased after compared to before receiving nutrition education: 'I eat meat or eggs more than 5 times a week,' 'I eat seafood at least three times a week,' 'I eat vegetables at every meal,' 'I eat fruits every day,' and 'I eat milk or dairy products every day.' These results indicate that the patients changed their dietary habit from a monotonous eating pattern to a pattern of consuming various food groups after receiving nutrition education. These results suggest that continuous nutrition care by clinical dietitians, according to the patient's treatment process, can help improve the patient's nutritional status and establish healthy eating habits.