• 한국전문물리치료학회지
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• 제5권2호
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• pp.98-105
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• 1998

The purposes of this article are to review the pathogenesis, prevention, and management of amputation due to diabetes mel1itus complications, and to report one case who had lost his toes due to diabetes mellitus. A primary cause for hospital admission of the patient was foot ulcer. Since many amputations in diabetic patients are precipitated by such ulcers, a program for active prevention and optimal treatment of diabetic foot lesions might decrease the risk of amputation. Diabetic foot ulcers and, ultimately, amputation can stem from a variety of pathways. The combination of peripheral neuropathy, peripheral vascular disease and infections is the harbinger of the final cataclysmic events of gangrene and amputation. As the physical therapist is often involved in the treatment of diabetic patients, the therapist should be aware of the followings: the patient's type of diabetes and the severity of the diabetes, the complications of the disease, the effects of exercise, the importance of wearing proper shoes and education to patients about appropriate diabetic foot care.

• 치과방사선
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• 제18권1호
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• pp.53-66
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• 1988

Irradiation is widely used for the treatment of malignant diseases, and possibly cause the osteoporosis. The bone densitometry and bone scintigraphy are valuable when used to monitor the patients longitudinally to access the progression of osteoporosis and risk of osteoradionecrosis. To evaluate the osteoporosis after irradiation of cobalt-60 gamma ray on the lumbar spines of New Zealand white rabbits, bone densitometry by dual photon absortiometry and bone scintigraphy were performed weekly. The decrease of bone density began at the first week after irradiation, and were in the nadir at 4-6th week. The osteoblastic activity measured by bone scintigraphy decreased in the first week, and was in the nadir at 4-6th week. The severity of these changes were related to the radiation dose. In conclusion, the osteoporosis before presentation of the osteoradionecrosis can be developed at low dose irradiation and confirmed by bone densitometry, bone scanning, and histopathology.

• International Journal of Human Ecology
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• 제13권1호
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• pp.1-16
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• 2012

Information about the characteristics of street-living versus shelter-residing youth is vital for tailoring prevention and intervention efforts to the unique needs of runaway and homeless youth. The present study compared two samples of youth [street-living (n=73) versus shelter-residing (n=205)], between the ages of 14 to 17 years, on behavioral and emotional factors and service use. Based on the different characteristics of the two groups, the predictors explaining the living status of the runaways and homeless youth were explored. In general, street-living youth reported more severe substance use, depressive symptoms, and risky sexual behavior, but less lifetime service involvement compared to shelter-residing youth. The factors that predicted shelter-residing status were related to younger age, prior service care experience, more knowledge about HIV, and engaging in less delinquent and risky behavior. Given the little overlap among youth in service involvement and the greater severity faced by street-living youth, the conclusions highlight the need for increased funding and attention towards facilitating the ability of street-living youth to find and enter mental health and reintegration services.

• 산업기술연구
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• 제32권A호
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• pp.125-128
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• 2012

In this paper, we proposed a prioritization method of test cases using a value estimation model of test sets, that are key elements for highly effective software testings as well as involve a large cost factor in software developments and maintenances. Based on previous studies, our idea includes introducing some practical factors of the test case prioritization which critically influence the value of a test case: Relative values of test sets before and after the test running, Average value of these two relative values, Severity of the defect, Risks that are covered, Frequency of use, Change related values, Systematic elicitations, etc. Finally we discussed the usefulness and the expected effects of the proposed scheme.

• 산업경영시스템학회지
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• 제22권53호
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• pp.79-88
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• 1999

This paper presents an integral model for product safety and product liability resulting from a defective product. The essence of the paper is the process of supply of manufacturing products which satisfy the product liability and the product safety in terms of consumers expectation levels. The main criteria of the product safety is the hazard level which involves in the severity and frequency. The proposed model shows the process to supply the manufactured products under the conditions that they are suitable in comparison of hazard level and safety level established by each company. If the product do not meet the safety level, this paper proposes that four different types of PL and PS countermeasures for the risk types are forward, respectively.

• Osteoporosis and Sarcopenia
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• 제3권3호
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• pp.117-122
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• 2017

Sarcopenia is the degenerative loss of muscle mass and function with aging. Recently sarcopenia was recognized as a clinical disease by the International Classification of Disease, 10th revision, Clinical Modification. An imbalance between protein synthesis and degradation causes a gradual loss of muscle mass, resulting in a decline of muscle function as a progress of sarcopenia. Many mechanisms involved in the onset of sarcopenia include age-related factors as well as activity-, disease-, and nutrition-related factors. The stage of sarcopenia reflecting the severity of conditions assists clinical management of sarcopenia. It is important that systemic descriptions of the disease conditions include age, sex, and other environmental risk factors as well as levels of physical function. To develop a new therapeutic intervention needed is the detailed understanding of molecular and cellular mechanisms by which apoptosis, autophagy, atrophy, and hypertrophy occur in the muscle stem cells, myotubes, and/or neuromuscular junction. The new strategy to managing sarcopenia will be signal-modulating small molecules, natural compounds, repurposing of old drugs, and muscle-specific microRNAs.

• International Journal of Reliability and Applications
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• 제4권4호
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• pp.183-190
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• 2003

Rail breaks and derailments can cause a huge loss to rail players due to loss of service, revenue, property or even life. Maintenance has huge impact on reliability and safety of railroads. It is important to identify factors behind rail degradation and their risks associated with rail breaks and derailments. Development of mathematical models is essential for prediction and prevention of risks due to rail and wheel set damages, rail breaks and derailments. This paper addresses identification of hazard modes, estimation of probability of those hazards under operating, curve and environmental condition, probability of detection of potential hazards before happening and severity of those hazards for informed strategic decisions. Emphasis is put on optimal maintenance and operational decisions. Real life data is used for illustration.

• International journal of thyroidology
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• 제11권2호
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• pp.71-74
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• 2018

Adverse events such as hemoptysis and gastrointestinal hemorrhage during tyrosine kinase inhibitor treatment are relatively rare, but the severity of the bleeding can be higher than other common adverse events. It is necessary to educate patients about its possibility so that they can be found early. In this case report of radioiodine refractory thyroid cancer patient, hemoptysis and gastrointestinal bleeding has occurred following lenvatinib administration. Drug interruption and dose modification and dose interruption were required in addition to management for bleeding itself. It is necessary to confirm the high risk of bleeding before the administration of tyrosine kinase inhibitors, and to appropriately control the follow-up interval and drug dosage accordingly.

• Archives of Plastic Surgery
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• 제49권3호
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• pp.405-412
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• 2022

Although modern medicine has made great strides in the management of burn injuries, associated complications such as pain, infection, dyspigmentation, and scarring have yet to be fully dealt with. Although skin grafting and meshing are routinely performed on burn patients, this method poses a risk for adverse effects. Activated autologous platelet-rich plasma (aaPRP), which is increasingly used in the field of plastic surgery, contains growth factors beneficial for wound regeneration. Seven cases of burns with varying severity and conditions that were treated with intralesional subcutaneous injection and intravenous aaPRP are presented and discussed herein. This case series indicates that subcutaneous and intravenous aaPRP is a safe procedure with the potential to be an alternative when skin grafting cannot be done or as an adjunct treatment to skin grafting.

• 국제학술발표논문집
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• The 9th International Conference on Construction Engineering and Project Management
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• pp.213-221
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• 2022

Defects are the risk factors in the construction process of buildings. They cause damage, delaying the construction duration. They especially cause adverse effects on the top-down construction method. This study analyzed the degree of construction delay induced by each work type, focusing on defects in the top-down method. Then, we derived construction delay induction coefficient from different work types in order by using the severity of construction delay per defect and the occurrence probability of defect; this assessment model measures the impact of defects on construction delay for each work type. Furthermore, by comparing each work type based on the defect frequency and the construction delay induction coefficient, we found work types that need to be administered attentively. We identified that plastering work was easy to overlook, requiring caution in defect management. This study provides an efficient defect management system suitable for the buildings that are built using the top-down construction method.