• Nuclear Engineering and Technology
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• v.52 no.1
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• pp.69-77
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• 2020

After the Fukushima Daiichi accidents, public concerns on nuclear safety and the corresponding burden of nuclear power plant licensees are increasing. In order to secure public trust and enhance the rationality of current safety regulation, we develop a risk-informed decision making (RIDM) framework for the Korean regulatory body. By analyzing all the regulatory activities for nuclear power plants in Korea, eight action items are selected for RIDM implementation, with appropriate procedures developed for each. For two items in particular - the accident sequence precursor analysis (ASPA) and the significance determination process (SDP) - two customized risk evaluation software has been developed for field inspectors and probabilistic safety assessment experts, respectively. The effectiveness of the proposed RIDM framework is demonstrated by applying the ASPA procedure to 35 unplanned scrams and the SDP to 24 findings from periodic inspections.

• Korean Journal of Plant Resources
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• v.34 no.6
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• pp.616-632
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• 2021

We performed taxonomic reviews and habitat circumstances survey for 41 un-introduced environmentally harmful plants (as designated by the Ministry of Environment, Korea in 2016). And we investigated plant specimens from several herbaria and performed a field survey in the southeastern region of the United States. Based on the result, we presented the most comprehensive results of weed risk evaluation and taxonomic description up to now as well as classification keys for 11 species to apply the regulation management of putative invasive alien species - Senecio madagascariensis Poir., Sphagneticola trilobata (L.) Pruski, Ageratina riparia (Regel) R.M. King & H. Rob. (Asteraceae), Andropogon gayanus Kunth (Poaceae), Echinocystis lobata (Michx.) Torr. & A. Gray (Cucurbitaceae), Salvinia minima Baker (Salviniaceae), Vincetoxicum rossicum (Kleopow) Barbar. (Asclepiadaceae), Asparagus asparagoides (L.) Druce (Asparagaceae), Alternanthera pungens Kunth (Amaranthaceae), Salpichroa origanifolia (Lam.) Thell., and Lycium ferocissimum Miers (Solanaceae).

• Fire Science and Engineering
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• v.20 no.3 s.63
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• pp.65-70
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• 2006

From the beginning of the construction stage, the fire protection regulation for the nuclear power plants conforms to the design requirements for the acquisition of the license permit. This regulation is based on the plant status of the normal operation, but it is not enough to be used as an application standard for fire protection at the transient mode of the plant and the outage time for refueling as well as for the plant decommissioning. While the advanced fire protection requirement that has been developed in America recently suggests the performance-based requirement and management rule applicable to the overall life time of the plant, it simply represents the conceptual application. It means that it can not be treated as appropriate standards because it does not deal with the qualitative and quantitative approach in specific ways. By the way, with the use of the performance-based fire risk analysis, the dynamic behavior of the heat and smoke at the fire compartment of the nuclear power plants can be analyzed and the thermal effect to the safety-related equipment and cables can be evaluated as well. At this paper, it suggests the ways to change the applicable fire protection regulations and the required evaluation items for the fire risk resulted from the plant configuration change with an intent to introduce the state-of-the-art quantitative fire risk analysis technology at the domestic nuclear power plants.

• Journal of the Korean Society of Safety
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• v.21 no.3 s.75
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• pp.67-72
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• 2006

This study is to investigate the related materials such as domestic law regulation, research paper, research report, and the other material, and to suggest suitable counter measures, to find out hazard degree for its works of workers and work place through direct survey, in order to determine risk score of each hazardous work which is designated by the Government, without consideration of labour's consciousness against risk level at a site. Therefore, a new questionnaire survey related to the decision of risk level are made and distributed to find out what risk level each worker recognizes. Also, the authors tried to approach reasonable conclusions after discussing reasonability of qualification standard and improving ideas of worker at hazardous work places with worker, faculty member, H&S manager, labour union. And the results show hazard degrees by each work kind of the above: 3.75 for working with machinery, 3.7 for steel structure, 3.5 for operation of tower crane, 3.51 for retaining wall, 3.85 for form work, 3.46 for scaffolding are obtained. This quantified risk can be applied to establishing a reasonable system to keep safe against hazardous works.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.11
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• pp.1113-1122
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• 2020

The purpose of this study is to examine how the Indian banks have adjusted their risk-based capital ratios during 2009-2018 to meet the regulatory requirements. Banks can, in principle, increase their risk-based regulatory capital ratio, either by increasing their levels of regulatory capital or by shrinking their risk-weighted assets by adjusting asset growth or risk in the portfolio. We investigate banks' capital behavior by decomposing the change in the capital ratio into the contribution of its components and analyzing their variance across regulatory regimes and banks' ownerships. We further investigate how each component of the capital ratio is adjusted by the banks by breaking down them into balance sheet items. We find that the banks' capital behavior significantly differed between public and private sector banks and between the two regulatory regimes. During Basel II, banks, in general, followed a strategy of aggressive asset growth with increased risk-taking. The decline in the CRAR because of such an expansionary strategy was adjusted by augmenting additional capital. However, during Basel III, due to higher capital requirements, both in terms of quantity and quality, banks followed a strategy of cutting back their asset growth and reducing the risk in their portfolio to maintain their CRAR.

• Journal of Biomedical Engineering Research
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• v.44 no.1
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• pp.19-24
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• 2023

Due to the spread of COVID-19, many patients with severe respiratory diseases have occurred worldwide, and accordingly, the use of mechanical ventilators has exploded. However, hospitals do not have systematic risk management, and the Medical Device Regulation also provides medical device risk management standards for manufacturers, but does not apply to devices in use. In this paper, we applied the Failure Mode Effects Analysis (FMEA) risk analysis technique based on the International Standard ISO 14971 (Medical Devices-Application of risk management to medical devices) for 85 mechanical ventilators of a specific model in use in hospitals. Failure modes and effects of each parts were investigated, and risk priority was derived through multiplication of each score by preparing criteria for severity, occurrence, and detection for each failure mode. As a result, it was confirmed that the microprocessor-based Patient Unit/Monitoring board in charge of monitoring scored the highest score with 36 points, and that reliability management is possible through systematic risk management according to priority.

• Journal of Microbiology and Biotechnology
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• v.30 no.2
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• pp.248-258
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• 2020

The vaginal microbiota may be important for pregnancy prognosis because vaginal dysbiosis during pregnancy appears to be related to preterm birth (PTB) or pregnancy loss. Previous reports have indicated that a Lactobacillus-poor microbial flora in the vagina and intrauterine infection by diverse anaerobes ascending from the vagina are associated with undesirable delivery outcomes. However, no research has involved the use of pyrosequencing analysis to examine vaginal microbiota profiles or their potential associations with high-risk pregnancy in Korean women. Vaginal swabs were collected from 500 Korean women for the identification of community state types (CSTs). Of these, 137 samples were further analyzed using a Roche/454 GS Junior pyrosequencer. Three distinct CSTs were identified based on the dominant vaginal microbes: CST I (Lactobacillus crispatus dominated), CST III (Lactobacillus iners dominated), and CST IV (with diverse species of anaerobes). Twelve of the 67 pregnant women had undesirable pregnancy outcomes (four miscarriages and eight PTBs). The dominant microbe in the vaginal microbiota of women who gave birth at full-term was L. crispatus. In contrast, L. iners was the dominant vaginal microbe in women who miscarried. Most (n = 6/8) vaginal microbiota profiles of women who experienced PTB could be classified as CST IV, with diverse bacteria, including anaerobic vaginal species. The present study provides valuable information regarding the characteristics of the vaginal microbiota of Korean women related to high-risk pregnancy. Investigation of the vaginal microbiotic structure in pregnant Korean women is necessary to enable better prediction of adverse pregnancy outcomes.

• Analytical Science and Technology
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• v.34 no.3
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• pp.99-114
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• 2021

Substance identification is the first step in implementing chemical legislation, such that subsequent hazard and risk assessments can be accurately followed. Based on the web page and related guidance documents of the European Chemicals Agency and available consortia information, the procedure for substance identification carried out in Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) is surveyed. In this study, the importance of substance identification and substance sameness check, as well as the necessity of generating a substance identity profile (SIP) are considered. In addition, the SIPs of several substance types are presented, which focused on information utilization in the instrumental analysis results and organization of information to generate the SIP. Analytical science can contribute to the accurate and effective implementation of chemical regulation at the starting stage of substance identification. However, understanding of the regulation and consequent final wrap-up of analytical results as a SIP should be followed for communication among registrants in Substance Information Exchange Forum (SIEF) as well as with related authorities.

• Korean Journal of Exercise Nutrition
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• v.24 no.3
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• pp.25-31
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• 2020

[Purpose] Epidemiological evidence has shown that leisure-time physical activity and structured exercise before and after breast cancer diagnosis contribute to reducing the risk of breast cancer recurrence and mortality. Thus, in this review, we aimed to summarize the physical activity-dependent regulation of systemic factors to understand the biological and molecular mechanisms involved in the initiation, progression, and survival of breast cancer. [Methods] We systematically reviewed the studies on 1) the relationship between physical activity and the risk of breast cancer, and 2) various systemic factors induced by physical activity and exercise that are potentially linked to breast cancer outcomes. To perform this literature review, PubMed database was searched using the terms "Physical activity OR exercise" and "breast cancer", until August 5th, 2020; then, we reviewed those articles related to biological mechanisms after examining the resulting search list. [Results] There is strong evidence that physical activity reduces the risk of breast cancer, and the protective effect of physical activity on breast cancer has been achieved by long-term regulation of various circulatory factors, such as sex hormones, metabolic hormones, inflammatory factors, adipokines, and myokines. In addition, physical activity substantially alters wholebody homeostasis by affecting numerous other factors, including plasma metabolites, reactive oxygen species, and microRNAs as well as exosomes and gut microbiota profile, and thereby every cell and organ in the whole body might be ultimately affected by the biological perturbation induced by physical activity and exercise. [Conclusion] The understanding of integrative mechanisms will enhance how physical activity can ultimately influence the risk and prognosis of various cancers, including breast cancer. Furthermore, physical activity could be considered an efficacious non-pharmacological therapy, and the promotion of physical activity is probably an effective strategy in primary cancer prevention.

• The Journal of Fisheries Business Administration
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• v.47 no.1
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• pp.87-100
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• 2016

Suhyup Bank became to be subject to regulation of capital ratio by Basel III which was introduced in order to enhance stability of the financial institution. Accordingly, Suhyup Bank will require recapitalization. It is important to estimate the risk-weighted assets in calculating of Suhyup Bank's recapitalization scale. Therefor, this study aimed to present a scientific model as estimated the risk-weighted assets. Risk-weighted assets are calculated by applying different risk weights for loans, may have a certain relationship with the loans. Results show that the risk-weighted assets is affected by the previous year's risk-weighted assets and influenced the increase in loans during the year. Since the required basic capital adequacy ratio was specified, the risk-weighted assets should be predicted reasonably. Accordingly, on this study it was tried to derive the accounting equation to predict the risk-weighted assets based on management data of a bank since introduction of Basel III. As the risk-weighted assets were weighted differently according to the type of loans, if the accounting equation is derived by using the type of loans, then it would be helpful for the risk management of banks in the long-term. According to this, the increase of loan would be predicted on the basis of past management performance of Suhyup Bank, and for this reason, the future risk-weighted assets of Suhyup Bank were predicted. The result of this study was showed that 98.3% of risk-weighted assets of the previous year, 62.4% of the secured loan changes and 95.1% of the credit loan changes affected risk-weighted assets.