• 제목/요약/키워드: Risk Probability

검색결과 1,139건 처리시간 0.027초

제 2형 당뇨병을 이용한 로지스틱과 베이지안 노모그램 구축 및 비교 (Nomogram comparison conducted by logistic regression and naïve Bayesian classifier using type 2 diabetes mellitus (T2D))

  • 박재철;김민호;이제영
    • 응용통계연구
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    • 제31권5호
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    • pp.573-585
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    • 2018
  • 본 연구에서는 제 2형 당뇨(type 2 diabetes mellitus)의 발병 확률을 예측하기 위해 11가지 위험요인을 가지고 로지스틱 회귀모형과 순수 베이지안 분류기 모형에 적합시킨다. 그런 다음 이를 시각적으로 쉽게 이해하는데 도움을 주는 노모그램 구축 방법을 소개한다. 분석은 2013-2015년 6기 국민건강영양조사 데이터를 가지고 분석하였다. 또 로지스틱 회귀모형에 세 가지 상호작용 항을 넣어 분석의 질을 높이고자 하였고 베이지안 노모그램에 left-aligned 방법을 사용하여 비교하기 쉽게 만들었다. 최종적으로 두 노모그램을 비교하고 효용성을 알아보았다. 마지막으로 ROC 곡선을 이용하여 노모그램이 적절한지 검증하였다.

국제결혼 부부의 연령 및 교육수준 격차와 결혼안정성: 국제결혼개방성 가설의 검증 (Spousal Dissimilarity in Age and Education and Marital Stability among Transnational Couples in Korea: A Test of the Transnational Openness Hypothesis)

  • 김두섭
    • 한국인구학
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    • 제35권1호
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    • pp.1-30
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    • 2012
  • 이 연구의 주된 목적은 한국에 거주하는 국제결혼 부부의 사회인구학적 상이성이 결혼안정성에 미치는 영향을 파악하는 것이다. 이 연구는 "2009년 전국 다문화가족 실태조사" 자료를 활용하여 국제결혼이 연령과 교육수준이 동질적인 선택혼(positive assortative matching)의 형태로 이루어지는가의 여부를 확인하고자 시도하였다. 그리고 외국인 아내의 출신국가별로 부부의 연령상이성과 교육상이성 지수를 계산하고, 이 지수들과 평균 결혼지속기간과의 관계를 분석하였다. 이 연구는 또한 미시수준에서 부부의 연령 및 교육수준 격차가 결혼만족도, 결혼지속기간과 이혼확률의 편차를 설명하는데 얼마나 도움이 되는가를 검증하였다. 이 연구의 분석결과, 국제결혼 부부의 연령과 교육수준 격차가 내국인 부부들의 경우보다 현저하게 크게 나타나는 것으로 확인되었다. 또한, 외국인 아내를 구하는 한국 남자들이 배우자와의 사회인구학적 격차에 대해 보다 개방적이고 융통적일 것이라고 가정한 국제결혼개방성 가설(the transnational openness hypothesis)이 지지되었다. 부부의 사회인구학적 격차가 커질수록 결혼의 해체가능성이 높아지고 결혼지속기간이 짧아질 것이라는 기존 연구의 가설은 한국에 거주하는 국제결혼 부부들에는 적용되지 않는 것으로 밝혀졌다.

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Surgical Perspective of T1799A BRAF Mutation Diagnostic Value in Papillary Thyroid Carcinoma

  • Brahma, Bayu;Yulian, Erwin Danil;Ramli, Muchlis;Setianingsih, Iswari;Gautama, Walta;Brahma, Putri;Sastroasmoro, Sudigdo;Harimurti, Kuntjoro
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권1호
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    • pp.31-37
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    • 2013
  • Background: Throughout Indonesia, thyroid cancer is one of the ten commonest malignancies, with papillary thyroid carcinoma (PTC) in our hospital accounting for about 60% of all thyroid nodules. Although fine needle aspiration biopsy (FNAB) is the most reliable diagnostic tool, some nodules are diagnosed as indeterminate and second surgery is common for PTC. The aim of this study was to establish the diagnostic value and feasibility of testing the BRAF T1799A mutation on FNA specimens for improving PTC diagnosis. Materials and Methods: This prospective study enrolled 95 patients with thyroid nodules and future surgery planned. Results of mutational status were compared with surgical pathology diagnosis. Results: Of the 70 cases included in the final analysis, 62.8% were PTC and the prevalence of BRAF mutation was 38.6%. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for BRAF mutation analysis were 36%, 100%, 100% and 48%, respectively. With other data findings, nodules with "onset less than 5 year" and "hard consistency" were proven as diagnostic determinants for BRAF mutation with a probability of 62.5%. This mutation was also a significant risk factor for extra-capsular extension. Conclusions: Molecular analysis of the BRAF T1799A mutation in FNAB specimens has high specificity and positive predictive value for PTC. It could be used in the selective patients with clinical characteristics to facilitate PTC diagnosis and for guidance regarding extent of thyroidectomy.

교대근무 간호사의 혈액과 체액 노출 사고 예측 요인과 감염예방행위의 매개효과: 영과잉 가산 자료 분석방법을 적용하여 (Predictors of Blood and Body Fluid Exposure and Mediating Effects of Infection Prevention Behavior in Shift-Working Nurses: Application of Analysis Method for Zero-Inflated Count Data)

  • 류재금;최스미
    • 대한간호학회지
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    • 제50권5호
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    • pp.658-670
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    • 2020
  • Purpose: This study aimed to identify the predictors of blood and body fluid exposure (BBFE) in multifaceted individual (sleep disturbance and fatigue), occupational (occupational stress), and organizational (hospital safety climate) factors, as well as infection prevention behavior. We also aimed to test the mediating effect of infection prevention behavior in relation to multifaceted factors and the frequency of BBFE. Methods: This study was based on a secondary data analysis, using data of 246 nurses from the Shift Work Nurses' Health and Turnover study. Based on the characteristics of zero-inflated and over-dispersed count data of frequencies of BBFE, the data were analyzed to calculate zero-inflated negative binomial regression within a generalized linear model and to test the mediating effect using SPSS 25.0, Stata 14.1, and PROCESS macro. Results: We found that the frequency of BBFE increased in subjects with disturbed sleep (IRR = 1.87, p = .049), and the probability of non-BBFE increased in subjects showing higher infection prevention behavior (IRR = 15.05, p = .006) and a hospital safety climate (IRR = 28.46, p = .018). We also found that infection prevention behavior had mediating effects on the occupational stress-BBFE and hospital safety climate-BBFE relationships. Conclusion: Sleep disturbance is an important risk factor related to frequency of BBFE, whereas preventive factors are infection prevention behavior and hospital safety climate. We suggest individual and systemic efforts to improve sleep, occupational stress, and hospital safety climate to prevent BBFE occurrence.

퍼지기반 해양 미생물 이용 수소 제조 공정의 고장유형 및 영향분석 (Fuzzy Based Failure Mode and Effect Analysis (FMEA) of Hydrogen Production Process Using the Thermococcus Onnurineus NA1)

  • 박성호;안준건;김수현;유영돈;장대준;강성균
    • 한국수소및신에너지학회논문집
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    • 제29권4호
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    • pp.307-316
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    • 2018
  • In this study, the failure mode and effect analysis (FMEA) of hydrogen production process by using the Thermococcus onnurineus NA1 was conducted and advanced methodology to compensate the weakness of previous FMEA methodology was applied. To bring out more quantitative and precise FMEA result for bio-hydrogen production process, fuzzy logic and potential loss cost estimated from ASPEN Capital Cost Estimator (ACCE) was introduced. Consequently, risk for releasing the flammable gases via internal leakage of steam tube which to control the operating temperature of main reactor was caution status in FMEA result without applying the fuzzification and ACCE. Moreover, probability of the steam tube plugging caused by solid property like medium was still caution status. As to apply the fuzzy logic and potential loss cost estimated from ACCE, a couple of caution status was unexpectedly upgraded to high dangerous status since the potential loss cost of steam tube for main reactor and decrease in product gases are higher than expected.

안전운전을 위해 위험지역을 회피하는 내비게이션 경로탐색 (Searching a Navigation Path to Avoid Danger Area for Safe Driving)

  • 이용후;김상운
    • 전자공학회논문지
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    • 제50권8호
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    • pp.171-179
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    • 2013
  • 내비게이션은 차량 운전자에게 경로탐색과 길안내 서비스의 제공을 기본으로 한다. 그러나 현재의 경로탐색에서는 운전자의 안전을 지키기 위해 다양한 도로 상황을 고려하지 않고, 안전운전 DB만을 이용하여 최단경로를 찾는 서비스만을 제공하고 있다. 따라서 안전운전을 위해서는 단순한 최단경로 검색 서비스를 벗어나, 위험지역이나 위험시간대를 고려한 경로탐색이 필요하다. 본 논문에서는 A* 알고리즘을 이용하여 안전운전을 위해 위험지역을 회피할 수 있는 경로탐색 방법을 제안한다. 이 경로탐색에서 탐색노드의 경로 적합 도를 측정할 때 위험지역 종류별로 서로 다른 휴리스틱 가중치를 적용하였다. 특히 경로 탐색에서 회피할 위험지역으로는 사고가 자주 발생하는 사고 다발구간, 어린이 보호구역, 교차로지역, 그리고 위험시간대를 고려하여 동적으로 위험지역별 가중치를 부여하였다. 컴퓨터 시뮬레이션 결과, 안전운전을 위해 위험지역을 회피할 수 있는 경로탐색 서비스를 제공할 수 있는 가능성을 확인하였다.

한국형 틸팅차량 설계의 비틀린 궤도상의 탈선안전도 검토 (The review of safety against derailment on twisted track for Korean tilting train design)

  • 김남포;김정석;박태원
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2005년도 춘계학술대회 논문집
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    • pp.299-307
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    • 2005
  • The 180 km/h Korean Tilting Train(TTX) which is now developing as a part of the Korean National R&D project, was elaborately designed. As the tilting trains run curve track with the $30\%$ higher speed than normal trains, the higher centrifugal and dynamic force are expected. Furthermore the complex tilting system increase the probability of failure. Therefore it is very important for tilting train to ensure safety against derailment under the various kind of failed condition in the middle of running as well as normal operating condition. The TTX train have the relatively high roll stiffness to improve the lateral ride comfort and to limit the roll displacement on the curve. But the higher roll stiffness increase the risk of derailment on the twisted track. This paper describes the study to review the safety against derailment caused by the wheel unloading on the severely twisted track. The worst combination of maximum cant change with maximum twist defect was established by numerical simulation. And also it was assumed that the air bag deflated and still the train run its speed limit. Those kind of assumption might be the worst case from the view point of wheel unloading derailment on the twisted track. The dynamic simulation was done by means of VAMPIRE S/W and non-linear transient analysis. We found that derailment quotients Q/P was only slightly influenced by track twist but the wheel unloading was greatly influenced. And we ascertained that the higher roll stiffness the higher wheel unloading. In case of air bag deflated situation, the wheel unloading reached up to $100\%$ which means the wheel lift or jumped. Therefore it was concluded that the design need to be improved to ensure the safety against derailment on the maximum twisted track in case of air bag deflated and tilting train's speed limit.

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Simulation of Effects of Swine Manure Application Rates on Nitrate Concentration in Runoff, Indiana, USA

  • Lim, Kyoung-Jae;Engel, Bernard A.;Jeon, Ji-Hong;Jones, Don;Sutton, Alan L.;Ok, Yang-Sik;Kim, Ki-Sung;Choi, Joong-Dae
    • 한국환경농학회지
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    • 제28권1호
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    • pp.38-46
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    • 2009
  • Livestock manure is an important source of nutrients for crop production. However, farmers typically do not know the exact nutrient values for livestock manure. In many instances, manure has been viewed as a waste, and as a result it is applied close to the source resulting in over application of nutrients. Thus, the goal of nutrient application has often been applied to reduce the application expense rather than to maximize crop income. This results in wasted money and potentially negative impacts on water quality. Several livestock manure management scenarios were created based on agronomic nutrient requirements using the Utilization of Animal Manure as a Plant Nutrient (AMANURE) software to investigate water quality impacts with the National Agricultural Pesticide Risk Analysis (NAPRA) WWW modeling system. Application of manure at agronomic rates can result in high nitrate-nitrogen losses for some soil types, especially when applied in late fall. The application of manure at an agronomic rate does not necessarily equate to adequate water quality protection, and farmers must take care applying manure at agronomic rates, because nitrate-nitrogen loss potential varies spatially and temporarily. Nutrient loss probability maps for Indiana at 5%, 10%, 25%, and 50% values were created to demonstrate potential water quality impacts when livestock manure is applied to cropland at agronomic rates. The NAPRA WWW system coupled with AMANURE can be used to identify site-specific livestock manure management plans that are environmentally sound and agronomically appropriate.

와이불 수명지수에 의한 고전압 케이블의 전압열화 측정값의 선형성 확인 (Linearity Verification of Measured Voltage Deterioration of High Voltage Cable based on Weibull Lifetime Index)

  • 엄기홍;이관우
    • 한국인터넷방송통신학회논문지
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    • 제16권1호
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    • pp.227-232
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    • 2016
  • 전력 수요량은 매년 증가추세에 있으며, 발전소에서 동작하는 모든 장비들과 대용량의 장거리 전력수송을 위한 장비들은 전력 소비자들이 기대하는 바 신뢰할 수 있는 수준에서 완전한 상태로 동작하여야 한다. 일반적으로, 고전력 송전을 위하여 사용되고 있는 케이블은 동작수명이 30년 이라고 제작 시에 선언된다. 케이블은 동작을 시작함과 동시에 성능이 악화되는 열화과정(케이블의 전기적 특성이 악화되는)이 시작된다. 열화로 인한 신뢰성의 손상이 발생함에도 불구하고, 동작상태의 신뢰성을 진단을 받지 않았기 때문에, 언제 불의의 사고를 초래할지 예측을 할 수 없을 만큼 위험한 상태에서 동작을 하고 있는 실정이다. 우리는 케이블의 열화과정을 진단하기 위하여 진단 장비를 제작하였고, 충청남도 태안의 (주)서부발전에 설치하여 시운전 하고 있는 중이다. 우리는 측정장비를 이용하여 추출한 데이터를 얻은 결과를 시간에 따라 변동 하는 그래프로 표시하여 분석한 특성을 이전 논문들에서 제시하였다. 이 논문에서는 이전 논문에서의 측정값으로 나타낸 그래프가 Weibull 확률분포에 의한 열화 이론과 일치하는 지를 확인하고, 결과를 제시한다.

Diagnostic Value of Rectal Bleeding in Predicting Colorectal Cancer: a Systematic Review

  • Tong, Gui-Xian;Chai, Jing;Cheng, Jing;Xia, Yi;Feng, Rui;Zhang, Lu;Wang, De-Bin
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권2호
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    • pp.1015-1021
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    • 2014
  • This study aimed at summarizing published study findings on the diagnostic value of rectal bleeding (RB) and informing clinical practice, preventive interventions and future research areas. We searched Medline and Embase for studies published by September 13, 2013 examining the risk of colorectal cancer in patients with RB using highly inclusive algorithms. Data for sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and positive predictive value (PPV) of RB were extracted by two researchers and analyzed applying Meta-Disc (version 1.4) and Stata (version 11.0). Methodological quality of studies was assessed according to QUADAS. A total of 38 studies containing 5,626 colorectal cancer patients and 73,174 participants with RB were included. The pooled sensitivity and specificity were 0.47 (95% CI: 0.45-0.48) and 0.96 (95% CI: 0.96-0.96) respectively. The overall PPVs ranged from 0.01 to 0.21 with a pooled value of 0.06 (95% CI: 0.05-0.08). Being over the age of 60 years, change in bowel habit, weight loss, anaemia, colorectal cancer among first-degree relatives and feeling of incomplete evacuation of rectum appeared to increase the predictive value of RB. Although RB greatly increases the probability of diagnosing colorectal cancer, it alone may not be sufficient for proposing further sophisticated investigations. However, given the high specificity, subjects without RB may be ruled out of further investigations. Future studies should focus on strategies using RB as an "alarm" symptom and finding additional indications to justify whether there is a need for further investigations.