• Journal of Preventive Medicine and Public Health
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• 제32권2호
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• pp.155-161
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• 1999

Objectio ostinato the carcinogenic risks from the ingestion of some carcinogenic pesticides (CPs) in vegetables sampled at a local agricultural product market in Seoul. Methods: After applying a hazard identification step, we selected four pesticides, such as DDT, dieldrin, folpet, and heptachlor epoxide, for this risk assessment. Concentrations of each pesticide were measured from randomly sampled vegetables. In order to estimate the human exposure levels, we combined the concentration of pesticides in the vegetables with consumption rate of those vegetables. Three scenarios were hypothesized for human exposure assessment. Scenario I was the most conservative which supposed the undetected CPs would be the detection limit values. Scenario II was assumed that the undetected CPs would be a half of the detection limit values, and finally scenario III merely considered only values greater than the detection limit values. We finally presented the estimated carcinogenic risks on the basis of the traditional risk assessment procedure suggested by U.S. EPA. Results: Pesticides including DDT, dieldrin, folpet and heptachlor epoxide were detected in 9 samples (6%) in the range of $0.0006\sim0.09ppm$. The daily intake levels of carcinogenic pesticides were estimated in the range of $0.0009\sim0.0079{\mu}g/day$. As we expected, excess cancer risks based on scenario I was also the highest $(1.1\times10^{-8}\sim5.5\times10^{-5})$. Conclusions: We found that the estimated risks from the pesticides we investigated were not serious. We, however, propose that a continuos monitoring is needed to make sure for the protection of public health.

• 여성건강간호학회지
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• 제15권1호
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• pp.54-63
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• 2009

Purpose: This study was done to develop an integrated breast health program for prevention and early detection of breast cancer, integrating primary and secondary prevention factors using cognitive-behavioral strategies. Method: This methodological study conducted as follows; Selection of components for the program through a literature review, survey to identify women's knowledge and risk perception of breast cancer and diet, and building prototype for the program using discussion based on findings. Using structured questionnaires, interviews were done with 130 women aged 40-59 who lived in a rural area. Result: Primary prevention (diet pattern, knowledge about breast cancer, and risk perception) and secondary prevention (early detection behaviors) factors were identified through the literature review. The survey showed that women lack knowledge and awareness about the risks of breast cancer, and have a low compliance rate for early detection behavior. Based on these results, a program was developed utilizing counseling and models to provide education and practice related to diet, breast cancer, and early detection behaviors. Conclusion: Use of this integrated and tailored breast health program with women at risk will contribute to better breast health, but further study is needed to verify the effects.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2018년도 추계학술논문요약집
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• pp.255-256
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• 2018

• 제어로봇시스템학회논문지
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• 제6권2호
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• pp.207-216
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• 2000

This paper introduces an effective system design method to develop a customer oriented product using a design optimization process and to select a set of critical design paramenters,. The process results in the development of a successful product satisfying customer needs and reducing development risk. The proposed scheme adopted a five step QFD(Quality Function Deployment) in order to extract design parameters from customer needs and evaluated their priority using risk factors for extracted design parameters. In this process we determine critical design parameters and allocate them to subsystem designers. Subsequently design engineers develop and test the product based on these parameters. These design parameters capture the characteristics of customer needs in terms of performance cost and schedule in the process of QFD, The subsequent risk management task ensures the minimum risk approach in the presence of design parameter uncertainty. An application of this approach was demonstrated in the development of weld quality monitoring system. Dominant design parameters affect linearity characteristics of weld defect feature vectors. Therefore it simplifies the algorithm for adopting pattern classification of feature vectors and improves the accuracy of recognition rate of weld defect and the real time response of the defect detection in the performance. Additionally the development cost decreases by using DSP board for low speed because of reducing CPU's load adopting algorithm in classifying weld defects. It also reduces the cost by using the single sensor to measure weld defects. Furthermore the synergy effect derived from the critical design parameters improves the detection rate of weld defects by 15% when compared with the implementation using the non-critical design parameters. It also result in 30% saving in development cost./ The overall results are close to 95% customer level showing the effectiveness of the proposed development approach.

• 한국철도학회논문집
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• 제12권6호
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• pp.921-926
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• 2009

신뢰도 기반 유지보수의 연구가 진행됨에 따라 설비의 신뢰도를 바탕으로 한 효율적인 유지보수 업무가 가능하게 되었다. Risk Priority Number(RPN)는 시스템을 구성하고 있는 설비에 대한 Severity(S), Occurrence(O), Detection(D)을 각각 평가하고 이를 하나의 통합된 수치로 표현함으로써 설비간의 유지보수 우선순위에 관한 정보를 제공한다. 하지만 철도 전력 설비와 같이 통계적인 고장 데이터가 부족하거나 신뢰성이 떨어지는 경우에는 이들의 평가가 객관적으로 이루어지기 어렵다. 따라서 본 논문에서는 설비의 Occurrence를 평가하기 위해 퍼지 이론을 이용한 고장률 가공 방법을 제시하고, 객관적인 Severity와 Detection 평가를 이용하여 Risk Priority Number를 계산하는 새로운 방법을 제시하였으며, 이를 철도 변전소 모의 시스템에 적용시켜 보았다.

• 품질경영학회지
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• 제47권1호
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• pp.97-108
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• 2019

Purpose: The purpose of this study is to propose a new Risk Priority Number(RPN) evaluation method which analyzes value of product functions by mining customer opinions in Social Network Service(SNS). Methods: A traditional RPN is measured by three evaluation standards (Severity, Occurrence, Detection) which are analyzed by manufacturing engineers and researchers. On the other hand, these standards are analyzed by customers' viewpoints through SNS opinion mining in this research. In order to extract customer feedbacks from textual data sets, the methodology in this paper implies natural language processing, hereby collecting product related data sets and analyzing the opinions automatically. An emotional polarity of an opinion indicates severity, while the number of negative opinion shows occurrence, and the entire number of customer opinion refers to detection. Results: The results of this study are as follows; As a result of the CRPN evaluation, it is confirmed that the features evaluated as risky are highly likely to be improved in the next series. Therefore, CRPN is an effective risk assessment model that reflects customer feedback. Conclusion: Reflecting customer feedback is a useful tool for risk assessment of the product as well as for developing new products and improving existing products.

• Journal of Preventive Medicine and Public Health
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• 제46권4호
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• pp.165-172
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• 2013

A noncommunicable disease (NCD) is a medical condition or disease that is by definition non-infectious and non-transmissible among people. Currently, NCDs are the leading causes of death and disease burden worldwide. The four main types of NCDs, including cardiovascular disease, cancer, chronic lung disease, and diabetes, result in more than 30 million deaths annually. To reduce the burden of NCDs on global health, current public health actions stress the importance of preventing, detecting, and correcting modifiable risk factors; controlling major modifiable risk factors has been shown to effectively reduce NCD mortality. The World Health Organization's World Health Report 2002 identified tobacco use, alcohol consumption, overweight, physical inactivity, high blood pressure, and high cholesterol as the most important risk factors for NCDs. Accordingly, the present report set out to review the prevalence and trends of these modifiable risk factors in the Korean population. Over the past few decades, we observed significant risk factor modifications of improved blood pressure control and decreased smoking rate. However, hypertension and cigarette smoking remained the most contributable factors of NCDs in the Korean population. Moreover, other major modifiable risk factors show no improvement or even worsened. The current status and trends in major modifiable risk factors reinforce the importance of prevention, detection, and treatment of risk factors in reducing the burden of NCDs on individuals and society.

• 한국수자원학회논문집
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• 제53권4호
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• pp.313-322
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• 2020

국토의 70% 이상이 산지인 우리나라의 경우 산지지역의 돌발호우로 인한 수재해의 위험이 상시 존재한다. 본 연구에서는 환경부 비슬산 강우레이더 관측 영역의 산지지역에 발생한 돌발성 호우 사례를 대상으로 레이더 기반 돌발성 호우 사전 예측 방법을 적용하여, 그 활용성을 살펴보았다. 비슬산 강우레이더의 3차원 레이더 반사도, 강우강도, 도플러 풍속을 이용하여, 산지지역에서 발생한 8개의 국지적 호우 사례를 선정한 후 적란운 대류세포의 조기탐지, 탐지된 대류세포의 자동 추적, 해당 대류세포가 발달하여 돌발성 호우를 유발할 수 있는 가능성을 판단하는 위험도 정보를 산출하였다. 사례적용 결과, 대기 중에 돌발호우로 발달할 수 있는 대류세포의 최초 탐지시점 및 위치, 소용돌이도 발생여부에 따라 판정된 위험도 수준 및 발생시점, 위치를 확인할 수 있었다. 특히, 지상강우관측망으로는 좁은 영역에 국지적으로 발달하는 호우를 탐지하는데 한계가 있음을 확인하였다. 또한, 위험도 정보를 획득한 시점에서 최대 강우강도가 발생할 때까지 최소 10분에서 최대 65분 정도의 시간을 확보함으로써 레이더 기반의 돌발성 호우 사전 예측기법은 산지지역에서 호우로 인한 산지홍수, 고립사고 방지를 위한 사전정보로 활용성이 있을 것으로 판단되었다.

• 벤처창업연구
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• 제8권2호
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• pp.53-61
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• 2013

본 연구는 프로스펙트이론을 적용하여 납세순응 문제를 다루었다. 납세순응의 결과는 소득 신고에서 나타나므로 원천징수에 따라 추가 납부와 환급 상황에 있는 두 개의 기업과 하나의 창업기업을 대상으로 세무대리인의 소득 신고액을 실험 기법으로 조사하였다. 프로스펙트이론에서는 이득 영역에서는 위험 회피, 손실 영역에서는 위험 선호로 의사결정자의 가치함수가 달라지므로 추가 납부 상황의 기업은 손실 상황의 기업으로 보아 소득 신고액이 감소하고, 환급 상황의 기업은 이득 상황의 기업으로 보아 소득 신고액이 증가한다고 본다. 창업기업은 준거점이 zero이므로 손실 상황이 아니라고 볼 수 있으나 기업의 재무 상태는 초기 투자로 인해 손실 상황일 것이다. 따라서 창업기업은 손실 상황의 기업과 동일한 방향으로 소득 신고가 이루어질 것이라고 볼 수 있다. 이에 대한 가설을 검증한 결과 창업기업이 소득 신고액이 가장 낮고 그 다음이 손실 상황의 기업이고 이익 상황의 기업이 소득 신고액이 가장 많았다. 두 번째 납세순응행위에 영향을 미치는 또 하나의 중요한 요인은 세무조사 적발률이다. 세무조사 적발률을 높이면 납세순응이 커진다. 이에 대한 가설을 검증한 결과 손실 상황의 기업, 이익 상황의 기업은 세무조사 적발률이 높아지면 소득 신고액이 증가하였다. 그러나 창업기업에 대해서는 통계적으로 검증이 되지 못하였다. 세 번째 세무대리인의 납세자 옹호성향과 위험선호 성향이 강할수록 프레이밍 효과가 커질 것이라는 가설에 대한 검증 결과 세무 대리인의 납세자 옹호성향이 증가할수록 창업기업과 손실 상황의 기업의 소득 신고액은 감소하고 이익 상황의 기업의 소득 신고액은 증가하였고 통계적으로 지지를 받았다. 반면 세무대리인의 위험선호 성향이 증가할수록 창업기업과 손실 상황의 기업의 소득 신고액은 감소하고 통계적으로 지지를 받았으나 이익 상황의 기업에 대해서는 통계적 지지를 받지 못하였다. 본 연구는 원천징수율, 적발률과 가산세율 등이 납세 순응 행위나 태도에 미치는 영향을 조사함으로써 정부의 정책 결정, 기업의 세무대리인 선정, 세무대리인의 적정 소득 신고 등에 도움이 될 것이며, 창업기업에 대해서는 최초의 연구이므로 그 의미가 더 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3629-3633
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• 2014

Background: Glioblastoma (GBM) is an immunosuppressive tumor whose median survival time is only 12-15 months, and patients with GBM have a uniformly poor prognosis. It is known that heredity contributes to formation of glioma, but there are few genetic studies concerning GBM. Materials and Methods: We genotyped six tagging SNPs (tSNP) in Han Chinese GBM and control patients. We used Microsoft Excel and SPSS 16.0 statistical package for statistical analysis and SNP Stats to test for associations between certain tSNPs and risk of GBM in five different models. ORs and 95%CIs were calculated for unconditional logistic-regression analysis with adjustment for age and gender. The SHEsis software platform was applied for analysis of linkage disequilibrium, haplotype construction, and genetic associations at polymorphism loci. Results: We found rs891835 in CCDC26 to be associated with GBM susceptibility at a level of p=0.009. The following genotypes of rs891835 were found to be associated with GBM risk in four different models of gene action: i) genotype GT (OR=2.26; 95%CI, 1.29-3.97; p=0.019) or GG (OR=1.33; 95%CI, 0.23-7.81; p=0.019) in the codominant model; ii) genotypes GT and GG (OR=2.18; 95%CI, 1.26-3.78; p=0.0061) in the dominant model; iii) GT (OR=2.24; 95%CI, 1.28-3.92; p=0.0053) in the overdominant model; iv) the allele G of rs891835 (OR=1.85; 95%CI, 1.14-3.00; p=0.015) in the additive model. In addition, "CG" and "CGGAG" were found by haplotype analysis to be associated with increased GBM risk. In contrast, genotype GG of CCDC26 rs6470745 was associated with decreased GBM risk (OR=0.34; 95%CI, 0.12-1.01; p=0.029) in the recessive model. Conclusions: Our results, combined with those from previous studies, suggest a potential genetic contribution of CCDC26 to GBM progression among Han Chinese.