• Journal of Wellbeing Management and Applied Psychology
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• v.7 no.4
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• pp.15-20
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• 2024

Purpose: Climate change is greatly affecting the frequency and intensity of fires around the world. The main effects of climate change on fires are rising temperatures, dry seasons and extreme droughts, changes in precipitation, increased strong winds, extended fire danger periods, and changes in natural ecosystems. Several factors due to climate change are increasing the risk of large-scale fires, such as wildfires. Research design, data and methodology: Rising temperatures caused by climate change will make forests and grasslands drier, make it easier for wildfires to occur in drier environments and spread quickly to wider areas, and the generated wildfires will release large amounts of greenhouse gases into the atmosphere, such as carbon dioxide (CO₂), and the released greenhouse gases will strengthen the global greenhouse effect, further raising the temperature. As temperatures rise, the risk of wildfires increases in drier environments, and this process is repeated, leading to a vicious cycle of intensifying climate change as more fires occur and more greenhouse gases are released. Results: In conclusion, climate change is increasing the risk of fire occurrence and this phenomenon is expected to become more frequent and severe in the future. Conclusions: In order to cope with the increasing fire risk caused by climate change, fire prevention and management. Fire detection and response systems need to be strengthened, supportive policies and international cooperation are needed to restore ecosystems, and these measures, along with fire prevention, management and countermeasures, should take into account long-term climate change and adaptation as well as short-term responses.

• Korean Journal of Clinical Pharmacy
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• v.32 no.3
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• pp.204-214
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• 2022

Objective: This study aimed to investigate the occurrence and types of the adverse events (AEs) associated with oral fluconazole and itraconazole and factors associated with specific types of AEs. Methods: We analyzed AEs reported by community pharmacies nationwide over 10 years using the Korea Adverse Event Reporting System database. Various AE terms were categorized into 18 types, and concomitant medications were classified by drug-drug interaction (DDI) severity. The relationship between the specific type of AE and age, sex, and number of concomitant medications was investigated using multiple logistic regression analysis. Results: A total of 879 AE reports of fluconazole and 401 reports of itraconazole were analyzed; of these reports, 321 and 83 reports of fluconazole and itraconazole, respectively, described concomitant drug administration categorized as DDI severity of contraindicated or major. Women had a higher risk of psychiatric AEs associated with fluconazole use (OR, 1.587; p=0.042). Polypharmacy increased the risk for psychiatric AEs (OR, 3.598; p<0.001 for fluconazole and OR, 2.308; p=0.046 for itraconazole). In dermatologic AEs, the mean age of patients who received itraconazole was lower than that of patients who received fluconazole (46.3±16.8 vs. 54.9±15.4; p<0.001). Co-administration of fluconazole with 1-3 drugs increased the risk of neurological AEs (OR, 1.764; p=0.028). Conclusion: When using fluconazole and itraconazole, psychiatric AEs should be noted, particularly in women and in case of polypharmacy; moreover, when fluconazole is co-administered with other drugs, attention should be paid to the occurrence of neurological AEs.

• Toxicological Research
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• v.26 no.4
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• pp.301-313
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• 2010

Growth promoters including hormonal substances and antibiotics are used legally and illegally in food producing animals for the growth promotion of livestock animals. Hormonal substances still under debate in terms of their human health impacts are estradiol-$17\beta$, progesterone, testosterone, zeranol, trenbolone, and melengestrol acetate (MGA). Many of the risk assessment results of natural steroid hormones have presented negligible impacts when they are used under good veterinary practices. For synthetic hormonelike substances, ADIs and MRLs have been established for food safety along with the approval of animal treatment. Small amounts of antibiotics added to feedstuff present growth promotion effects via the prevention of infectious diseases at doses lower than therapeutic dose. The induction of antimicrobial resistant bacteria and the disruption of normal human intestinal flora are major concerns in terms of human health impact. Regulatory guidance such as ADIs and MRLs fully reflect the impact on human gastrointestinal microflora. However, before deciding on any risk management options, risk assessments of antimicrobial resistance require large-scale evidence regarding the relationship between antimicrobial use in food-producing animals and the occurrence of antimicrobial resistance in human pathogens. In this article, the risk profiles of hormonal and antibacterial growth promoters are provided based on recent toxicity and human exposure information, and recommendations for risk management to prevent human health impacts by the use of growth promoters are also presented.

• Analytical Science and Technology
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• v.36 no.5
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• pp.224-235
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• 2023

An analytical method was developed for the determination of phenol (P) and the seven substituted phenols in water samples and fish tissue samples collected from three streams located in eastern Gangwon State in spring and summer. The phenols were extracted and then derivatized to phenyl acetates using acetic anhydride. The derivatives were subsequently identified and quantified using gas chromatography coupled with mass spectrometry. P and 4-nitrophenol (4NP) were found at relatively high levels in water, ranging from below the method detection limit (MDL) to 3.32 ㎍/L and from < MDL to 4.91 ㎍/L, respectively. P and 4NP were also the dominant compounds in the fish tissue, ranging from < MDL to 407 ㎍/kg and from < MDL to 870 ㎍/kg, respectively. Phenol concentrations were significantly higher in spring than in summer. The ecological risk quotient calculated for P was higher than 4NP but not high enough to pose any risk of adverse effects to fish health.

• Journal of Gastric Cancer
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• v.21 no.1
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• pp.16-29
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• 2021

Purpose: Incidence, risk factors, and clinical consequences of pancreatic fistula (POPF) after D1+/D2 radical gastrectomy have not been well investigated in Western patients, particularly those from Eastern Europe. Materials and Methods: A total of 358 D1+/D2 radical gastrectomies were performed by surgeons with high caseloads in a single surgical center from 2002 to 2017. A retrospective analysis of data that were prospectively gathered in an electronic database was performed. POPF was defined and graded according to the International Study Group for Pancreatic Surgery (ISGPS) criteria. Uni- and multivariate analyses were performed to identify potential predictors of POPF. Additionally, the impact of POPF on early complications and long-term outcomes were investigated. Results: POPF was observed in 20 patients (5.6%), according to the updated ISGPS grading system. Cardiovascular comorbidities emerged as the single independent predictor of POPF formation (risk ratio, 3.051; 95% confidence interval, 1.161-8.019; P=0.024). POPF occurrence was associated with statistically significant increased rates of postoperative hemorrhage requiring re-laparotomy (P=0.029), anastomotic leak (P=0.002), 90-day mortality (P=0.036), and prolonged hospital stay (P<0.001). The long-term survival of patients with gastric adenocarcinoma was not affected by POPF (P=0.661). Conclusions: In this large series of Eastern European patients, the clinically relevant rate of POPF after D1+/D2 radical gastrectomy was low. The presence of co-existing cardiovascular disease favored the occurrence of POPF and was associated with an increased risk of postoperative bleeding, anastomotic leak, 90-day mortality, and prolonged hospital stay. POPF was not found to affect the long-term survival of patients with gastric adenocarcinoma.

• Journal of Preventive Medicine and Public Health
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• v.55 no.5
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• pp.424-427
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• 2022

A retrospective record-linkage study (RLS) based on medical records containing drug prescription histories involves immortal time bias (ITB). Thus, it is necessary to control for this bias in the research planning and analysis stages. Furthermore, a summary of a meta-analysis including RLSs that did not control for ITB showed that specific drugs had a preventive effect on the occurrence of the disease. Previous meta-analytic results of three systematic reviews evaluating the association between statin intake and gastric cancer risk showed that the summary hazard ratio (sHR) of the RLSs was lower than 1 and was statistically significant. We should consider the possibility of ITB in the sHR of RLSs and interpret the results carefully.

• Proceedings of the KIPE Conference
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• 2016.07a
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• pp.32-33
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• 2016

Due to the frequent occurrence of dangerous wild animals in rural or mountainous areas. it has been increasing damage of crops in every year. Fight bell or electric fence is typically installed to chase those wild animals. But there are problems that it is impossible to drive out birds and spends high installation and maintenance cost. In addition, it is inefficient to the risk of electric shock effect. In this study, the proposed system can drive out hazardous wildlife and birds regardless of installation location through realtime detection with the multi-sensing based IoT platform technology. This study showed a very large significance effect that can reduce crop damage by wildlife and birds.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• v.y2005m4
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• pp.23-26
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• 2005

The method of decreasing the ecological risk for the LRE(Liquid Rocket Engine) test is developed, working on the cryogenic oxidizer and the high-boiling fuel(Kerosene). This Method is based on the study that contains a technical solution method and an accident occurrence range for decreasing of accident probability and damage. This paper contains schematic on the all risk circumstance bring to accident, block-diagram for an accident growth process in case of the propellant leakage, evaluation method of safety distance from test stand to residential area. It will be used to alternative method for the risk reduction of complex technical systems.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2021.05a
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• pp.53-54
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• 2021

Grenfell Tower was renovated in 2014 and 2016 at a high cost to replace the exterior materials, windows and co-heating facilities of the building. The exterior materials used during the repair work were sandwich panels filled with polyethylene and plastic, which were expanded on the aluminum metal surface. It is a product called Celotex RS 5000, a low-resolution but inexpensive repair material, and is currently an external material that cannot be used in high-rise buildings. Similar domestic fire cases began to focus social attention on the safety of high-rise buildings through the Busan Residential Complex Fire (2010), Uijeongbu Urban Living Housing Fire (2015), and Ulsan Residential Complex Fire (2020), and residents' safety concerns are increasing. In Korea, the occurrence and risk of similar fires are high, so setting up fire prevention measures through fire case investigation is considered the most basic measure in securing human safety. Therefore, the purpose of this study is to examine the status of fire damage caused by domestic and foreign eruptions, domestic and international research status and related regulations on external materials and windows starting from the Grenfell Tower fire in England.

• Journal of Korean Society for Geospatial Information Science
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• v.20 no.4
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• pp.97-104
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• 2012

Recent climate change has increased the occurrence of flood disaster. There are two approaches to prevent flooding damage. One is a structural method and the other is a non-structural method. The production and usage of a flood risk map are the example of non-structural way. The flood risk map displays several kinds of information to minimize casualties and property damage caused from flooding. In order to increase the usage of current flood risk maps and improve intuitive recognition of flood information, this paper produced flood risk maps based on geo-spatial information system using three dimensional virtual reality techniques and investigated the applicability of the maps. Because flood information is easily accessed through online, flood risk maps suggested in this paper are regarded as an efficient tool.