• Journal of Korean Ophthalmic Optics Society
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• v.21 no.2
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• pp.99-108
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• 2016

Purpose: The present study was aimed to compare the tear volume and distribution by corneal eccentricity when fitted with spherical and aspherical RGP lenses. Methods: Spherical and aspherical RGP lenses were fitted in best alignment on a total of 77 subjects (136 eyes) in their twenties and thirties without any ocular disease or ocular surgery experience. The tear volume was analyzed by estimating the concentration of tear stained with fluorescein in the center of RGP lens as well as at the mid-peripheral and peripheral areas, and the difference of tear distributions was analyzed according to corneal eccentricity. Results: Tear distribution from the center to the peripheral area was not significantly different when spherical RGP lenses were fitted on the corneal eccentricities of e < 0.38 and $0.68{\leq}e$, indicating the relatively even tear distribution compared with other corneal eccentricity. In the case of aspherical RGP lenses, the difference of tear distribution between the central and peripheral areas was smaller than spherical RGP lenses. The significant difference of tear distribution according to RGP lens design was observed in the corneal eccentricity of 0.48 < e < 0.68. In other words, more even tear distribution was shown when aspherical RGP lenses were fitted on the cornea with eccentricity of $0.48{\leq}e<0.68$ and spherical RGP lenses were fitted on the cornea with eccentricity $0.68{\leq}e$. Furthermore, tear volume in the mid-peripheral area increased with higher corneal eccentricity. Conclusions: The results suggest that the appropriate selection of RGP lens design according to corneal eccentricity is necessary since tear volume and distribution by the regions of spherical and aspherical lenses are affected by corneal eccentricity.

• Journal of Korean Ophthalmic Optics Society
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• v.15 no.4
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• pp.329-337
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• 2010

Purpose: The surfaces and compositions of rigid gas permeable (RGP) contact lenses were analyzed with the consistent methods, and the basic informations for the composition design of lens materials were suggested. Methods: The bulk structures were analyzed by using Fourier infrared spectroscopy (FTIR), the compositions of surface components were observed by using x-ray photoelectron spectroscopy (XPS), the surface morphology and roughness were observed using atomic force microscopy (AFM), and the wettabilities were estimated by the surface wetting angles. The relations and trends of those results were analyzed. Results: The high oxygen permeability RGP lenses showed the trend that the fluorine decreases and the silicon increases. As the silicon and fluorine contents increased, the carbon and oxygen contents of RGP lens materials decreased at a constant ratio. The decreasing ratio of the carbon contents was three times larger than the decreasing ratio of oxygen contents. The composition of the surface treated lens was far from these tendency line. When the silicon contents increased, the rough surface was formed with the cohered particles. When the fluorine contents increased, the rough surface was formed with the deep flaws. The surface roughness increased and then wettabilities decreased as the silicon and fluorine contents increased. For the surface roughness changes, the increasing ratio of the silicon contents was two times larger than the increasing ratio of fluorine contents. The surface of RGP lens materials appeared the hydrophobic character of which the wettabilities decreased when the roughnesses increased. Conclusions: The surfaces and compositions of RGP contact lenses were measured by the same methods. Those results and relationships were compared and analysed. It is considered that these research results will be applied with the basic data for the composition design of lens materials.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.1
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• pp.31-42
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• 2014

Purpose: The present study was conducted to investigate the effect of the physical properties of RGP lens induced by lens polishing on the actual wearer's subjective comfort, the tear film break-up time and the blinking rate as a follow-up study that revealed the relationship between the lens physical properties during lens manufacturing and lens wearer's factors. Methods: RGP lenses made from the three different polishing conditions (25, 50 and 100 seconds) were applied on 28 eyes of 17 subjects, aged 20 to 29 years, without any known disease and surgical history in the eyes. While the subjects were asked to wear the RGP lenses longer than a week, the questionnaire for the comfortability was administered everyday. Subjective and objective tear break-up time and blinking rate of the wearers were further measured. Results: The wearer's subjective comfortability showed some difference in the type of discomfort and satisfaction score according to the polishing status when wearing RGP lenses made from different polishing conditions longer than a week, and a bigger difference in satisfaction score induced by polishing condition was especially shown in experienced RGP lens wearer rather than un-experienced wearer. In the case of RGP lens wearer compared with the ones without the wearing experience, as the wearing time increased subjective and objective tear break-up time were increased and the blinking rate was decreased. However, subjective and objective tear break-up time were tended to decrease with even longer wearing time when wearing the RGP lens made from the polishment for 100 seconds. Conclusions: These results confirmed that the optimization of physical properties of the lens may not give the same effect on the wearer's subjective and objective symptoms and other factors when actual wearing. From the results, it can suggest that the success rate of RGP lens wear may be changed by physiological factors such as the stabilization of wearer's tear film, comfortability and lens wearing experience when wearing RGP lens based on 'The manufacturing standard for soft contact lens/hard contact lens' provided by Korea Food and Drug Administration.

• Journal of Korean Ophthalmic Optics Society
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• v.18 no.1
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• pp.27-35
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• 2013

Purpose: The present study was conducted to investigate the changes in the physical properties of RGP lenses induced by the polishing during the process of RGP lens manufacturing, and further evaluate the differences in the actual wearer's comfort and the tear film break-up time caused by these changes. Methods: RGP lenses (fluorosilicone acrylate material) were divided into 4 groups by the different lens-polishing time like 0, 25, 50 and 100 seconds and the thickness, the surface roughness and the wetting angle of those lenses were compared. Furthermore, the comfortability of the lens wear was surveyed after applying these lenses on the subject's eyes with normal tear volume and the non-invasive tear break-up time of the wearers was measured. Results: The central thickness of 4 RGP lenses made of different lens-polishing time was not significantly different however, the lens surface was changed smoother after polishing to be confirmed by scanning electron microscopy. The wetting angle of the RGP lens significantly decreased in accordance with the increase of polishing time. Thus, the difference of approximately $16^{\circ}$ between 0 second and 100 seconds-polishing was statistically significant. The actual wearing feeling of RGP lens was tended to improve in accordance with the increase of the lens wettability however, it was not proportional improvement. The non-invasive tear break-up time of the lens wearers showed different aspect compared with the changes in lens wettability and the actual feeling of RGP lens wear. Conclusions: In this study, better lens wettability, thinner lens thickness, and/or improved lens surface induced by physical stimuli in the process of RGP lens manufacturing was not well-correlated with the increase of actual subjective/objective satisfaction in RGP lens wear. Thus, the consideration of physical properties of the lens as well as the lens wearers' physiological factors in the process of RGP lens manufacturing may be suggested.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.2
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• pp.143-151
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• 2012

Purpose: The present study was conducted to investigate whether there is any difference in the centration of spherical RGP lens on cornea according to corneal types, corneal astigmatism and lens fitting states. Methods: Spherical RGP lens was fitted on 29 eyes of round-typed cornea and 45 eyes of symmetric bowtie-typed cornea with 0.00~2.75 D of corneal astigmatism in alignment, steep or flat. Their lens centrations on cornea were analyzed by taking photographs. Results: The centration of spherical RGP lens in the vertical direction was decentrated to downward direction in all cases, and the degree of decentration was not consistent. The lens centration in horizontal direction was significantly more-decentrated to the temporal meridian as base curve of lens was increased, and the degree of decentration was different according to the corneal type, corneal astigmatism and fitting states. With the same degree of astigmatism, the lens decentration to the temporal meridian was bigger in round-typed cornea than that in symmetirc bowtie-typed cornea. Conclusions: The centration of spherical RGP lens varies depending on lens fitting states, corneal astigmatism, and corneal types. Thus, the consideration of these factors may improve the success rate in RGP lens prescription.

• Applied Microscopy
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• v.36 no.3
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• pp.227-234
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• 2006

To investigate the comparative effect of spherical and aspherical RGP lens were worn during 3 weeks on rabbit's cornea. Four white rabbits were worn right eyes with spherical lens and 4 white rabbits were worn right eyes with aspherical RGP lens. Left eyes were served as control. The rabbits were sacrificed at 3 weeks after fitting and observed morphological changes by scanning electron microscopy and also investigate proliferation rate of the corneal epithelium with RGP wearing. After spherical RGP lens wearing, the epithet layer damaged compared to aspherical lens. The superficial cell layer strip off seriously, cell size significantly changed abnormal. Both spherical and aspherical RGP lens fitting group showed so many bacteria and back surface of lens was found like a fern shape. The aspherical RGP lens original material type was some formal than spherical lens. We thought that these pattern was significantly altered with spherical lens by prohibited transmitter oxygen from atmosphere therefore the epithelium shape was changed. This suggested wearing the aspherical lens might be less physiologic than shperical lens fitting.

• Journal of Korean Ophthalmic Optics Society
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• v.6 no.1
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• pp.55-58
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• 2001

The rigid gas permeable(RGP) contact lens has nearly side effect on the cornea. So that, this lens has used the clinical reflective correction of the eye. This study have used several methods for research the fine internal structure on the RGP contact lens by scanning electron microscopy. The results have indicated that the postfixation of 1% $OsO_4$ and tannic acid is responsible for a fine structure in the internal plane of RGP contact lens. These internal surface of contact lens appeared the several shape of the hole of the stereo shape form with arrangement of round form. But, on the contact lens with non-postfixation, the stereo shape have not present and the boundary of the vesicle have not clear. Maybe, these results suggest that the fixation methods have effect on the morphological characters of materials on the RGP contact lens.

• Food Science of Animal Resources
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• v.38 no.1
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• pp.64-77
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• 2018

Effects of quality, physicochemical properties and antioxidants in Camembert cheese added with red ginseng powder (RGP) were investigated. Cheese samples were prepared with 0.05%, 0.10%, 0.15% and 0.20% RGP. and then monitored during ripening at $14^{\circ}C$ for 28 d. The pH of the RGP amended treatment groups increased during the ripening period relative to the control (p<0.05). Moreover, the 1,2-Diphenyl-1-picrylhydrazyle (DPPH) was highest in the 0.15% RGP group from 21 d to 28 d. $ABTS^+$ radical scavenging activity was increased just like DPPH as the ripening period passed, 0.10% treatment was highest at from 7 d to 21 d. 0.15% RGP was contents of ginsenosides : 10,999.7 ppm. The Free fatty acids (FFA), controls with 0.15% treatment, while the total fat (TF) and monounsaturated fat (MuSF) were higher in the control than the 0.15% RGP group (p<0.05). The total free amino acid (FAA) was increased in the control, and 0.15% RGP, and control was highest at then 0.15% RGP. The samples had average contents of fat and protein were 29% and 18-20% respectively. Additionally, the $L^*$ value decreased, while the $a^*$ and $b^*$ values increased as the amount of RGP added increased. Sensory evaluation revealed that texture and total acceptability were higher in the control group at 12 d. Although the addition of RGP did not exert a better effect on the ripening of the camembert cheese, but the ripening grade was similar to that of the common camembert cheese, and the additional function of the cheese was reinforced. Functional cheese could be developed.

• Journal of Korean Ophthalmic Optics Society
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• v.8 no.2
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• pp.85-89
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• 2003

A tear lens formed by between back surface of spherical rigid gas permeable(RGP) contact lens and front surface of cornea shows an excellent correction effect of astigmatism. To study an effects of tear lens power using spherical RGP lens and therefore to utilize them in clinical procedures, we analyze a change of the total astigmatism, the cornea astigmatism, and the residual astigmatism, we derive the following conclusion. 1. Almost all refractive astigmatism below than 2.00D present fully corrected. Thereby resulting good visual acuity. Refractive astigmatism higher than 2.50D show under-corrected and apparent decrease of visual acuity if it is higher than 3.00D. 2. Amount of corneal astigmatism below than 2.50D show acceptable under-corrected while higher than 3.000 present unacceptable visual acuity. 3. An estimated residual astigmatism is not revealed as it is : but it is reduced when it incorporate to refractive astigmatism.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.3
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• pp.255-264
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• 2012

Purpose: In this study, the effect of lens fitting status on the contact area between spherical/aspherical RGP lens and the cornea having different astigmatic degree and corneal type was investigated for guiding the proper selection of RGP lens. Methods: Spherical and aspherical RGP lenses were applied on ninety eyes $(25.12{\pm}3.52years)$ having with-the-rule astigmatism by different fitting status. Then, their central, mid-peripheral and peripheral areas of fluorescein pattern were calculated and compared for the quantitative evaluation of the contact area between spherical/aspherical RGP lens. Results: The central and peripheral areas with the alignment fitting was significant different based on lens design. However, the central area didn't show any significant difference by lens design and corneal type when fitted in steep or flat. When analyzed by the corneal shape, both lenses with alignment and flat fitting had significant difference in central and peripheral areas. However, the central, mid-peripheral and peripheral areas with steep fitting didn't show the difference by corneal types. When analyzed by the astigmatic degree, the central and peripheral areas with alignment fitting changed proportionally to the increase of corneal astigmatism regardless of corneal shape. With steep and flat fitting, however, the central, mid-peripheral and/or peripheral areas in round- and symmetric bowtie-typed corneas showed the conflicting result when compared to those of alignment fitting when analyzed by the astigmatic degree. Conclusions: In this study, it was confirmed that the contact areas of cornea and RGP lens fitted steep and flat status were largely affected by the corneal type and corneal astigmatism rather than RGP lens fitted in alignment status. Also, this result commonly occurred in both spherical and aspherical RGP lenses.