• 척추신경추나의학회지
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• 제1권2호
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• pp.61-72
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• 2006

Objectives: The aim of this study is to investigate chiropractic spinal manipulation and internal diseases in articles. Methods: It was investigated how many articles had been searched for spinal manipulation applied to internal disease in Pubmed Database Results: 1. There are 19 articles of chiropractic spinal manipulation and internal diseases were investigated. 2. It was reported that there are improvements of spinal manipulative therapy on asthma, injury of the optic nerve, hypertension, vertigo, tinnitus, hearing loss, etc. Conclusions: There are several reports on effectiveness of spinal manipulative therapy on asthma, injury of the optic nerve, hypertension, vertigo, tinnitus, hearing loss, etc. And It is considered that spinal manipulative therapy shows improvement on the internal diseases.

• Mycobiology
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• 제49권2호
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• pp.95-104
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• 2021

Species of the genus Aspergillus have a variety of effects on humans and have been considered industrial cell factories due to their prominent ability for manufacturing several products such as heterologous proteins, secondary metabolites, and organic acids. Scientists are trying to improve fungal strains and re-design metabolic processes through advanced genetic manipulation techniques and gene delivery systems to enhance their industrial efficiency and utility. In this review, we describe the current status of the genetic manipulation techniques and transformation methods for species of the genus Aspergillus. The host strains, selective markers, and experimental materials required for the genetic manipulation and fungal transformation are described in detail. Furthermore, the advantages and disadvantages of these techniques are described.

• 미생물과산업
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• 제19권4호
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• pp.14-26
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• 1993

Optimizing protein production in recombinant E. coli strains involves manipulation of genetic and environmental factors. In designing a production system, attention must be paid to gene expression efficiency, culture conditions and bioreactor configuration. Although not much emphasis was given to the physiology of host strains in this review, an understanding of the relationship between the physiology of host cell growth and the overproduction of a cloned gene protein is of primary importance to the improvement of the recombinant fermentation processes. Sometimes it is desirable to make use of gene fusion systems, e.g. protein A, polypeptide, gutathione-S-transferase, or pneumococcal murein hydrolase fusion, to facilitate protein purification.

• 제어로봇시스템학회논문지
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• 제11권4호
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• pp.353-362
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• 2005

This article describes a state-of-the art review in nano-biomanipulation technologies. Nanomanipulation of biological objects enables an in-depth study of single molecules such as DNA and RNA, and of biophysical events at the molecular level like molecular motors. Controlled nanomanipulation is challenging but essential for precisely engineering biomolecules or cells and for manufacturing functional nano-biosystems. In this paper, we summarize several contact, non-contact and hybrid methods available for nanomanipulation of biological objects. Advantages currently available methods and their limitations are also compared. Finally, we discuss possible applications of nano-biomanipulation technologies to life science and molecular medicine including cell biology, genetic engineering, biophysics, and biochemistry.

• Current Optics and Photonics
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• 제8권1호
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• pp.16-29
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• 2024

This paper presents a comprehensive review of metasurface technology, focusing on its significant role in extraordinary flat optic functionalities. Traditional optical components, though optimized, are bulky and less congruent with modern integrated electromagnetic and photonic systems. Metasurfaces, recognized as the 2D counterparts of bulk metamaterials, offer solutions with their planar, ultra-thin, and lightweight structures. Their meta-atoms are adept at introducing abrupt shifts in optical properties, paving the way for high-precision light manipulation. By introducing the key design principles of these meta-atoms, such as the magnetic dipole and Pancharatnam-Berry phase, various applications in wavefront shaping and beam forming with simple amplitude/phase manipulation and advanced applications including retroreflectors, Janus metasurfaces, multiplexing of optical wavefronts, data encryption, and metasurfaces for quantum applications are reviewed.

• 한국수정란이식학회:학술대회논문집
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• 한국수정란이식학회 2002년도 춘계학술세미나 및 워크숍
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• pp.19-25
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• 2002

Researches on manipulation pluripotent stem cells derived from blastocysts or promordial germ cells (PGCs) have a great advantages for developing innovative technologies in various fields of life science including medicine, pharmaceutics, and biotechnology. Since the first isolation in the mouse embryos, stem cells or stem cell-like colonies have been continuously established in the mouse of different strains, cattle, pig, rabbit, and human. In the animal species, stem cell biology is important for developing transgenic technology including disease model animal and bioreactor production. ES cell can be isolated from the inner cell mass of blastocysts by either mechanical operation or immunosurgery. So, mass production of blastocyst is a prerequisite factor for successful undertaking ES cell manipulation. In the case of animal ES cell research, various protocol of gamete biotechnology can be applied for improving the efficiency of stem cell research. Somatic cell nuclear transfer technique can be applied to researches on animal ES cells, since it is powerful tool for producing clone embryos containing genes of interest. In this presentation, a brief review was made for explaining how somatic cell nuclear transfer technology could contribute to improving stem cell manipulation technology.

• Journal of Animal Science and Technology
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• 제60권6호
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• pp.15.1-15.10
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• 2018

Methane emission from the enteric fermentation of ruminant livestock is a main source of greenhouse gas (GHG) emission and a major concern for global warming. Methane emission is also associated with dietary energy lose; hence, reduce feed efficiency. Due to the negative environmental impacts, methane mitigation has come forward in last few decades. To date numerous efforts were made in order to reduce methane emission from ruminants. No table mitigation approaches are rumen manipulation, alteration of rumen fermentation, modification of rumen microbial biodiversity by different means and rarely by animal manipulations. However, a comprehensive exploration for a sustainable methane mitigation approach is still lacking. Dietary modification is directly linked to changes in the rumen fermentation pattern and types of end products. Studies showed that changing fermentation pattern is one of the most effective ways of methane abatement. Desirable dietary changes provide two fold benefits i.e. improve production and reduce GHG emissions. Therefore, the aim of this review is to discuss biology of methane emission from ruminants and its mitigation through dietary manipulation.

• 대한물리치료과학회지
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• 제10권1호
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• pp.212-221
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• 2003

To observe the anatomical structures which cause a cervicogenic headache it reports, from viewpoint of physical therapist in treatment multiple to observe method which approaches, the reporter it does. With the manipulation the vertebral manipulation effected an affirmative effect to cervicogenic headache(Niels Nilsson et al,1997). The manipulation, soft the tissue massage, postural education/advice, muscular elongation, the traction, and postural exercises initially came to be used with that technique which the upper cervical vertebra(0-C3) passive accessory intervertebral movement comes to be used with a cervicogenic headache treatment technique(Grant T & Niere K., 2000). Also, it relates with the diagnosis standard about a cervicogenic headache when the body function over of the cervical vertebra is discovered, the Muscle energy technique was proposed in the treatment which is safety and effect(Bogduk N,2001). The TENS and the Mange gave a reduction effect of pain often.

• 음성과학
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• 제14권3호
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• pp.31-46
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• 2007

This study attempts to investigate that the training of pitch manipulation would help Korean speakers reduce the intonation errors based on the review of many previous studies on Korean speakers' phonetic realization of intonation. The previous studies have indicated that Korean speakers have problems with pitch manipulation in their production of English word stress, sentence stress, and eventually intonation. To train Korean speakers phonetically realize English pitch patterns, a blended learning module was operated for two weeks: face-to-face instruction for six hours and e-learning instruction for three hours in total. This module was designed to help Korean speakers realize pitch as a distinctive phoneme. An acoustic assessment on five Korean female English speakers shows that the training of pitch manipulation helps Korean English speakers reduce the intonation errors indicated in the previous studies reviewed.

• 한방재활의학과학회지
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• 제18권4호
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• pp.103-120
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• 2008

Objectives : This study aims to educate clinical doctors of the valuable practice of Manipulative Therapy(MT) as an opportunity for evidence-based medicine. Consequently it also serves to review the effectiveness and safety of MT. Methods : The literature studies of overseas were done by Cochrane Library and Medline website; those of domestic researches were completed by utilizing the sources which are gained from KERIS, KISS, DBpia, Kisti, and domestic institutes related with MT. Results : Eight papers related to the effectiveness of MT were published in South Korea, which concluded with the positive effects of MT. None of them are, however, well-designed randomized controlled trials(RCT). On the other hand, fifteen cases of nine articles indicate the adverse reaction of MT, and numbers of the researches in overseas revealed the side effects of MT in order of cervical, lumbar, and thoracic vertebrae. A vascular adverse reaction such as vertebral and carotid artery dissection was a highly reported cervical adverse reaction; in the thoracic and lumbar regions, neurological adverse reaction in terms of disc hemiation was frequently discovered. Conclusions : Henceforth, highly qualitative studies are required developing the effective outcomes and preventing any possible complications of MT. Therefore, systemic curriculums in institutions and sufficient clinical training in the filed are strongly recommended.