• Journal of the Korean association of regional geographers
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• v.9 no.1
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• pp.66-76
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• 2003

Wetland is the ecotone between aquatic ecosystem and land ecosystem, and is much valuable in terms of ecology and economic. The stream wetland among inland fresh wetlands occupies the largest area but has been recognized as only a channel not a habitat. The purposes of this paper are to consider the characteristics of natural wetlands formed in the tributary flowing into the downstream reach of Nakdong River and to find its optimal management policy. Natural wetlands in the middle-size streams (2nd${\sim}$3rd order) are large marshlands, and were formed at the places from the mainstream away, because natural wetlands were formed in the reach of longitudinal profiles during the last glacial and the post-glacial period meet in disharmony. In order to conserve these natural wetlands effectively, we should compile the inventories of wetlands and make precise distribution maps. And we should do 'reverse-reclamation' which means the alteration of some farmlands reclaimed from natural wetland into natural wetland ecosystem, and develop the place or the space for wildlife education and ecotourism.

• The Korean Journal of Pain
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• v.18 no.2
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• pp.99-106
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• 2005

Background: Cyclic guanosine monophosphate (cGMP) and opioid receptors are involved in the modulation of nociception. Although the opioid receptors agonists are active in pain, the effect of an phospodiesterase inhibitor (zaprinast) for increasing the level of cGMP has not been thoroughly investigated at the spinal level. This study examined the effects of intrathecal zaprinast and morphine in a nociceptive test and we also examined the nature of the pharmacological interaction after the coadministration of zaprinast with morphine. The role of the nitric oxide (NO)-cGMP-potassium channel pathway on the effect of zaprinast was further clarified. Methods: Catheters were inserted into the intrathecal space of male SD rats. For the induction of pain, $50{\mu}l$ of 5% formalin solution was applied to the hindpaw. Isobolographic analysis was used for the evaluation of the drug interaction between zaprinast and morphine. Furthermore, NO synthase inhibitor ($_L-NMMA$), guanylyl cyclase inhibitor (ODQ) or a potassium channel blocker (glibenclamide) were intrathecally administered to verify the involvement of the NO-cGMP- potassium channel pathway on the antinociception effect of zaprinast. Results: Both zaprinast and morphine produced an antinociceptive effect during phase 1 and phase 2 in the formalin test. Isobolographic analysis revealed a synergistic interaction after the intrathecal administration of the zaprinast-morphine mixture in both phases. Intrathecal $_L-NMMA$, ODQ and glibenclamide did not reverse the antinociception of zaprinast in either phase. Conclusions: These results suggest that zaprinast, morphine and the mixture of the two drugs are effective against acute pain and they facilitated pain state at the spinal level. Thus, the spinal combination of zaprinast with morphine may be useful for the management of pain. However, the NO-sensitive cGMP-potassium channel pathway did not contribute to the antinocieptive mechanism of zaprinast in the spinal cord.

• Journal of Korean Society on Water Environment
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• v.24 no.4
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• pp.442-451
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• 2008

We analyzed characteristics of rainfall-runoff for the channel of Yongwon area made by a new port construction. And we conducted inundation analysis on the region of lower elevation near the coast. SWMM5 was calibrated with the storm produced by the typhoon Megi from August 19 to August 20 in 2004, and was verified with the storm from August 22 to August 22 in 2004. We performed hydraulic channel routing of Yongwon channel about typhoon Megi from August 19 to August 20 in 2004 by UNET model which is a hydraulic channel routing. The simulated runoff hydrographs were added to the new stream as lateral inflow hydrographs and a watershed runoff hydrograph was the upstream boundary condition. The downstream boundary condition data were estimated by the measured stage hydrographs. The maximum stage that was calculated by hydraulic channel routing was higher than the levee of inundated region in typhoon Megi. Thus we can suppose an inundation to have been occurred. We performed inundation analysis about typhoon Megi from August 19 to August 20 in 2004 and flood discharge of return period 10~150 years. And we estimated each inundation area. The inundation areas by return periods of storms were estimated by 3.4~5.7 ha. The causes of inundation are low heights of levee crests (D.L. 2.033~2.583 m), storm surges induced by typhoons and reverse flow through the coastal sewers (D.L. -0.217~0.783 m). A result of this study can apply to establish countermeasure of a flood disaster in Yongwon.

• Journal of Korea Water Resources Association
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• v.52 no.1
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• pp.1-10
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• 2019

This study investigates the flow characteristics, such as velocity distributions, size and location of recirculation zone, longitudinal flow change rates, and bifurcation discharge ratio in the bifurcation channel by TELEMAC-2D, a 2D numerical model. The numerical model is validated by previous experimental results and the numerical results are in relatively good agreement with the experimental results, such as the water surface elevation and velocity distribution in the channels. As the inertial force and moment in the main channel decrease, the bifurcation discharge ratio increases, and the relative high velocity distribution becomes wider and the reverse velocity of the main stream decreases in the branch channel. As the bifurcation discharge ratio increases, the size of the recirculation zone in the branch channel decreases and it can be more clearly calculated by determining the point where the longitudinal froude number $Fr{\approx}0$ as well as drawing the distribution of the streamline distribution.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.21 no.1
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• pp.161-174
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• 1996

Addressed in this paper is performance analysis of the maximum-likelihood code acquisition technique for slotted-mode preamble search in the CDMA reverse link. The probabilities of detection, miss, and false alarm are derived analytically for a multiple $H_{1}$ cell case in a frequency-selective Rayleigh fading channel, based on the statics of the CDMA noncoherent demodulator output. the probability density function of the decision variable consisting of successive demodulator outputs is also derived by considering the fading characteristics of the received signal for both single and dual antenna cases. The performance of the code acquisition technique is evaluated numerically with an emphasis on investigating the effects of post-detection integration, fading rate, and antenna diversity on the detection performance.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2003.06a
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• pp.852-855
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• 2003

Gas-Assisted Injection Molding(GAIM) process, that can be used to provide a hollow shape in a molding, is a variant of the conventional injection molding process. GAIM has many advantages such as reduction of material, sink mark. warpage. and lower injection pressure. Thus, GAIM has been widely applied in the industry to make moldings with a hollow channel such as handles, TV frames and so on. On the other hand, GAIM has some disadvantages such as slow cooling time and flow marks. In the disadvantages, hot gas core causes slow cooling of a molding and the overflow. which is to prevent flow mark. is waste of materials. To solve these problems, we developed a new GAIM system that we called RGIM(Reverse Gas Injection Molding). The RGIM has two special units; one is the overflow buffer, which is used for reduction of a material, and the other tile air unit, which is used for faster cooling of a molding. We conducted an experiment and simulation to verify the efficiency of the RGIM system. Through experiments and simulation, we confirmed the effectively operating of the RGIM system and extracted the optimum process conditions.

• Advances in concrete construction
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• v.9 no.5
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• pp.437-448
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• 2020

In high rise buildings that utilize precast large panel system for construction, the shear wall provides strength and stiffness during earthquakes. The performance of a wall panel system depends mainly on the type of connection used to transfer the forces from one wall element to another wall element. This paper presents an experimental investigation on different types of construction detailing of the precast wall to wall vertical connections under reverse cyclic loading. One of the commonly used connections in India to connect wall to wall panel is the loop bar connection. Hence for this study, three types of wet connections and one type of dry connection namely: Staggered loop bar connection, Equally spaced loop bar connection, U-Hook connection, and Channel connection respectively were used to connect the precast walls. One third scale model of the wall was used for this study. The main objective of the experimental work is to evaluate the performance of the wall to wall connections in terms of hysteretic behaviour, ultimate load carrying capacity, energy dissipation capacity, stiffness degradation, ductility, viscous damping ratio, and crack pattern. All the connections exhibited similar load carrying capacity. The U-Hook connection exhibited higher ductility and energy dissipation when compared to the other three connections.

• The Korean Journal of Pharmacology
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• v.32 no.2
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• pp.211-219
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• 1996

The inhibitory effect of cyclosporin A (CsA) on nitric oxide production is not related to the immunosuppressive action of the drug, but to the renal toxicity and arterial hyper-tension. In this study the experimental interventions to reverse the inhibition of nitric oxide production by cyclosporin A in rat aortic smooth muscle cells were examined. CsA inhibited the accumulation of nitrite, the stable end product of nitric oxide, in culture media in a concentration $(0.1{\sim}100{\mu}g/ml)-dependent$ manner. The inhibitory effect of CsA on nitrite accumulation were not antagonized by arginine (10 mM), a substrate of nitric oxide synthase, nor by calcium ionophore A23187 $(7{\mu}M)$. Forskolin, an activator of adenylate cyclase, which enhanced iNOS induction at transcriptional level, completely reversed the inhibitory action of CsA on nitrite accumulation. However, PMA (2 nM) and PDB (50 nM), PKC activators, increased the inhibitory action of CsA on nitrite accumulalion. From these results, it is suggested that cyclic AMP-elevating agents may be candidates of therapeutic agents in prevention and treatment of renal toxicity and arterial hypertension induced by CsA. Among conventional antihypertensive drugs, calcium channel blockers and ${\alpha}-blockers$ are preferred to ${\beta}-blockers$.

• Korean Circulation Journal
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• v.48 no.12
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• pp.1135-1144
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• 2018

Background and Objectives: Mitochondria play a key role in the pathophysiology of heart failure and mitochondrial permeability transition pore (MPTP) play a critical role in cell death and a critical target for cardioprotection. The aim of this study was to evaluate the protective effects of cyclosporine A (CsA), one of MPTP blockers, and morphological changes of mitochondria and MPTP related proteins in monocrotaline (MCT) induced pulmonary arterial hypertension (PAH). Methods: Eight weeks old Sprague-Dawley rats were randomized to control, MCT (60 mg/kg) and MCT plus CsA (10 mg/kg/day) treatment groups. Four weeks later, right ventricular hypertrophy (RVH) and morphological changes of right ventricle (RV) were done. Western blot and reverse transcription polymerase chain reaction (RT-PCR) for MPTP related protein were performed. Results: In electron microscopy, CsA treatment prevented MCT-induced mitochondrial disruption of RV. RVH was significantly increased in MCT group compared to that of the controls but RVH was more increased with CsA treatment. Thickened medial wall thickness of pulmonary arteriole in PAH was not changed after CsA treatment. In western blot, caspase-3 was significantly increased in MCT group, and was attenuated in CsA treatment. There were no significant differences in voltage-dependent anion channel, adenine nucleotide translocator 1 and cyclophilin D expression in western blot and RT-PCR between the 3 groups. Conclusions: CsA reduces MCT induced RV mitochondrial damage. Although, MPTP blocking does not reverse pulmonary pathology, it may reduce RV dysfunction in PAH. The results suggest that it could serve as an adjunctive therapy to PAH treatment.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.20 no.6
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• pp.183-194
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• 2010

A company's private network protected by a firewall and NAT(Network Address Translation) is not accessible directly through an external internet. However, as Reverse Connection technology used by NetCat extends to the technologies such as SSH Tunnel or HTTP Tunnel, now anyone can easily access a private network of corporation protected by a firewall and NAT. Furthermore, while these kinds of technologies are commercially stretching out to various services such as a remote control and HTTP Tunnel, security managers in a company or general users are confused under the circumstances of inner or outer regulation which is not allowed to access to an internal system with a remote control. What is more serious is to make a covert channel invading a company's private network through a malicious code and all that technologies. By the way, what matters is that a given security system such as a firewall cannot shield from these perceived dangers. So, we analyze the indirect access of technological methods and the status quo about a company's internal network and find a solution to get rid of the related dangers.