• 전자공학회논문지
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• 제49권12호
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• pp.156-163
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• 2012

최근 들어 정보은닉기술에 대한 필요성이 많이 증가되고 있으며 국제치안, 군사 그리고 의료영상 등의 분야에서 그 예를 많이 볼 수 있다. 본 논문에서는 한 픽셀의 다수 MSB(MSBs: Most Significant Bits)의 Parity Bit를 이용하여 gray영상에 대해 정보를 은닉하는 방법을 제안한다. 스테가노그라피(Steganography) 분야에서 많은 연구들이 LSB 대체(Substitution), XOR연산을 채용하여 연구되어왔으며 궁극적인 목적은 낮은 복잡도와 높은 은닉용량, 동시에 화질의 저하를 최소화하는 것이다. 하지만 LSB 대체 방법은 높은 은닉용량을 가짐에도 불구하고 너무나 간단한 작업으로 인해 안전하지 못하다. 또한 XOR연산을 이용한 방법들은 픽셀 수 대비 약 75%의 은닉률을 달성하였다. 제안된 방법에서 각 픽셀의 LSB(Least Significant Bit)는 비밀메시지 1비트와 해당 픽셀의 7 MSBs의 Parity Bit와 XOR 연산된다. 제안한 방법은 대칭키 프로토콜의 개념을 스테가노그라피에 적용한 것이며 대칭키를 자기참조에 의해 생성하도록 하였다. 제시한 방법은 기존의 XOR방법들에 비해 은닉률이 25% 높으며 원본 대비 픽셀의 LSB 반전률이 약 6%정도 개선되는 효과를 보였다.

• Environmental Sciences Bulletin of The Korean Environmental Sciences Society
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• 제4권3호
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• pp.173-183
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• 2000

This study measured the zeta potential of both latex colloidal particles with carboxylate surface groups and glass beads (collectors) with silanol surface group employing various solution with different chemical characteristics. The results have been compared with the surface chemistry theory. The zeta potential of the particle and collector increased with increasing pH up to 5.0 regardless of the solution chemistry. For a monovalent electrolyte solution(sodium chloride solution) the zeta potential steadily increased until the pH reached 9.5. In contrast, little change in zeta potential was made between 5.0 and 9.5 for a divalent electrolyte solution (sodium chloride solution) the zeta potential steadily increased until the pH reached 9.5. In contrast, little change in zeta potential was made between 5.0 and 9.5 for a divalent electrolyte solution (calcium chloride solution). In other words, the more the pH decreases, the larger the effect of neutral salts, such as NaCl and CaCl$_2$, have on the ζ-potential values. In this study, the PZPC(point of zero proton condition) of the particle and collector occurred below a pH of 3.1, H(sup)+ and OH(sup)- acted as a PDI (potential determining ion), and Na(sup)+ acted as an IDI(indifferent ion). The magnitude of the negative ζ-potential values of the particle and collector monotonically increased as the concentrations of Na(sup)+ or Ca(sup)2+([Na(sup)+] or [Ca(sup)2+]) decreased (the values of pNa or pCa increased). In the case of latex particles, the ζ-potential should aproach zero (isoelectric point; IEP) asymptotically as the pNa approaches zero, while in the case of calcium chloride electrolyte, ζ-potential reversal may be expected to occur around 3.16$\times$10(sup)-2MCaCl$_2$(pCa=1.5). pH, valance and ionic strength can be used in various ways to improve the water treatment efficiency by modifying the charge characteristics of the particle and collector. Predictive capability is far less certain when EDL(electrical double layer) repulsive forces exist between the particle and collector.

• Archives of Plastic Surgery
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• 제39권5호
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• pp.540-545
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• 2012

Background Patients have anxiety and fear of complications due to general anesthesia. Through new instruments and local anesthetic drugs, a variety of anesthetic methods have been introduced. These methods keep hospital costs down and save time for patients. In particular, the target-controlled infusion (TCI) system maintains a relatively accurate level of plasma concentration, so the depth of anesthesia can be adjusted more easily. We conducted this study to examine whether intravenous anesthesia using the TCI system with propofol and remifentanil would be an effective method of anesthesia in breast augmentation. Methods This study recruited 100 patients who underwent breast augmentation surgery from February to August 2011. Intravenous anesthesia was performed with 10 mg/mL propofol and 50 ${\mu}g/mL$ remifentanil simultaneously administered using two separate modules of a continuous computer-assisted TCI system. The average target concentration was set at 2 ${\mu}g/mL$ and 2 ng/mL for propofol and remifentanil, respectively, and titrated against clinical effect and vital signs. Oxygen saturation, electrocardiography, and respiratory status were continuously measured during surgery. Blood pressure was measured at 5-minute intervals. Information collected includes total duration of surgery, dose of drugs administered during surgery, memory about surgery, and side effects. Results Intraoperatively, there was transient hypotension in two cases and hypoxia in three cases. However, there were no serious complications due to anesthesia such as respiratory difficulty, deep vein thrombosis, or malignant hypertension, for which an endotracheal intubation or reversal agent would have been needed. All the patients were discharged on the day of surgery and able to ambulate normally. Conclusions Our results indicate that anesthetic methods, where the TCI of propofol and remifentanil is used, might replace general anesthesia with endotracheal intubation in breast augmentation surgery.

• 의료법학
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• 제19권1호
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• pp.207-254
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• 2018

2017년 주요 판결 중에는, 진료계약과 함께 체결되는 틀니제작계약의 법적성질을 분리하여 후자의 경우 도급적 성질이 있다는 판결과 태아보험은 계약체결 후 1회 보험료를 받은 후부터 그 효력이 발생한다는 보험법리를 활용하여 민법에서 논의되는 전부노출설의 한계를 극복한 판결이 선고되었다. 약화사고와 관련하여 의료인의 책임을 인정하는 판결이 증가하면서 직접 약을 제조 교부하는 약사의 복약지도 등을 강화해야 한다는 의견이 있었고, 감염관리와 관련하여 법원이 과실을 부정하는 방향으로 사실관계를 해석하거나 적용한 데 대한 비판과 함께 병원감염사건의 특수성에 비추어 병원감염 관리 및 그 피해 구제를 위한 제도적 장치마련, 소송법상 증명책임 전환 등 제도의 개선이 필요하다는 의견이 있었다. 설명의무 관련 판결에서는 이미 설명이 되었던 부분이나 설명을 하지 않더라도 해당 진료행위를 수행하였을 것이기 때문에 설명의 대상이 되지 않는다는 판례 등 설명의무의 대상과 관련한 판결들이 다수 선고되었고, 손해배상의 범위와 관련하여 유방을 흉부 장기로 보아 다발성 반흔 구축 및 변형을 장해로 인정한 사건이 선고되어 많은 논의를 불러 일으켰다. 진단서와 관련한 의료법 해석에 대한 대법원 판결은 법률 규정이 가진 해석범위를 넘은 유추해석이라는 지적이 있었다.

• 한국진공학회지
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• 제17권2호
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• pp.90-95
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• 2008

본 연구에서는 열 및 불산을 이용한 후처리 공정이 레지스트층을 이용하여 제작된 탄소나노튜브의 전자 방출 특성에 미치는 영향에 대하여 연구하였다. 전자 방출 전류는 초기에 $8V/{\mu}m$의 전계에서 $4.2{\mu}A/cm^2$의 전류에서 열 및 불산 처리 시 각각 $7.5mA/cm^2$ 및 $79mA/cm^2$로 향상되었다. 하지만 열 및 불산 처리를 동시에 실시한 경우 전류 밀도는 $426mA/cm^2$ 및 $656mA/cm^2$로 향상된 전자 방출 특성을 얻을 수 있었다. 전자 방출 특성은 처리 순서에 따라 증가하는 양이 다르게 나타났으며, 가장 우수한 전자 방출 특성은 열 처리를 먼저 시행 후, 불산 처리를 하는 공정에서 나타났다. 이는 열 처리에 의한 탄소나노튜브의 결정성의 증가와 이후 불산 처리에 의한 불소 결합의 증가에 기인함을 알 수 있었다. 강한 불소 결합은 탄소나노튜브 에미터의 전자 방출 특성의 향상에 크게 기여를 하였다.

• 한국식품위생안전성학회지
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• 제22권1호
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• pp.1-14
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• 2007

The term, "food safety", has traditionally been viewed as a practical science aimed at assuring the prevention acute illnesses caused by biological microorganisms, and only to a minor extent, chronic diseases cause by chronic low level exposures to natural and synthetic chemicals or pollutants. "food safety" meant to prevent microbiological agents/toxins in/on foods, due to contamination any where from "farm to Fork", from causing acute health effects, especially to the young, immune-compromised, genetically-predisposed and elderly. However, today a broader view must also include the fact that diet, perse (nutrients, vitamins/minerals, calories), as well as low level toxins and pollutant or supplemented synthetic chemicals, can alter gene expressions of stem/progenitor/terminally-differentiated cells, leading to chronic inflammation and other mal-functions that could lead to diseases such as cancer, diabetes, atherogenesis and possibly reproductive and neurological disorders. Understanding of the mechanisms by which natural or synthetic chemical toxins/toxicants, in/on food, interact with the pathogenesis of acute and chronic diseases, should lead to a "systems" approach to "food safety". Clearly, the interactions of diet/food with the genetic background, gender, and developmental state of the individual, together with (a) interactions of other endogenous/exogenous chemicals/drugs; (b) the specific biology of the cells being affected; (c) the mechanisms by which the presence or absence of toxins/toxicants and nutrients work to cause toxicities; and (d) how those mechanisms affect the pathogenesis of acute and/or chronic diseases, must be integrated into a "system" approach. Mechanisms of how toxins/toxicants cause cellular toxicities, such as mutagenesis; cytotoxicity and altered gene expression, must take into account (a) irreversible or reversal changes caused by these toxins or toxicants; (b)concepts of thresholds or no-thresholds of action; and (c) concepts of differential effects on stem cells, progenitor cells and terminally differentiated cells in different organs. This brief Commentary tries to illustrate this complex interaction between what is on/in foods with one disease, namely cancer. Since the understanding of cancer, while still incomplete, can shed light on the multiple ways that toxins/toxicants, as well as dietary modulation of nutrients/vitamins/metals/ calories, can either enhance or reduce the risk to cancer. In particular, diets that alter the embryo-fetal micro-environment might dramatically alter disease formation later in life. In effect "food safety" can not be assessed without understanding how food could be 'toxic', or how that mechanism of toxicity interacts with the pathogenesis of any disease.

• Journal of Ginseng Research
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• 제38권1호
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• pp.1-7
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• 2014

Background: Although ginsenosides such as Rg1, Rb1 and Rg3 have shown promise as potential nutraceuticals for cognitive impairment, their use has been limited due to high production cost and low potency. In particular, the process of extracting pure Rg3 from ginseng is laborious and expensive. Methods: We described the methods in preparing ginseol k-g3, an Rg3-enriched fraction, and evaluated its effects on scopolamine-induced memory impairment in mice. Results: Ginseol k-g3 (25-200 mg/kg) significantly reversed scopolamine-induced cognitive impairment in the passive avoidance, but not in Y-maze testing. Ginseol k-g3 (50 and 200 mg/kg) improved escape latency in training trials and increased swimming times within the target zone of the Morris water maze. The effect of ginseol k-g3 on the water maze task was more potent than that of Rg3 or Red ginseng. Acute or subchronic (6 d) treatment of ginseol k-g3 did not alter normal locomotor activity of mice in an open field. Ginseol k-g3 did not inhibit acetylcholinesterase activity, unlike donezepil, an acetylcholinesterase inhibitor. Rg3 enrichment through the ginseol k-g3 fraction enhanced the efficacy of Rg3 in scopolamine-induced memory impairment in mice as demonstrated in the Morris water maze task. Conclusion: The effects of ginseol k-g3 in ameliorating scopolamine-induced memory impairment in the passive avoidance and Morris water maze tests indicate its specific influence on reference or long-term memory. The mechanism underlying the reversal of scopolamine-induced amnesia by ginseol k-g3 is not yet known, but is not related to anticholinesterase-like activity.

• 대한감각통합치료학회지
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• 제12권2호
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• pp.25-36
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• 2014

목적 : 본 연구는 감각통합치료효과에 대한 단일대상연구의 특성을 파악하고 질적 수준을 알아보고자 하였다. 연구방법 : 대한작업치료학회, 국가과학기술정보센터(NDSL), 누리미디어(DBpia), 학술연구정보서비스(RISS), 한국학술정보(KISS), 국회도서관의 원문제공 서비스를 이용하여 2002년부터 2013년 까지 발간된 논문 중 '감각통합', '단일대상연구', '응용행동분석'을 주요검색용어를 사용하여 검색하였다. 17편의 단일대상연구 논문을 선별하여 연구방법과 연구 설계의 질적 수준을 분석하였다. 결과 : 연구 설계 방법으로는 반전설계가 가장 많았으며, 총 회기와 연구기간, 중재시간은 다양하였고 중재 장소는 작업치료실과 감각통합실에서 이루어졌다. 대상자는 지적장애가 가장 많았다. 질적 수준은 모든 연구들이 중간수준이상으로 나타났다. 결론 : 단일대상연구의 질적 수준은 어느 정도 보장되고 있었으나 연구방법에 대한 논의와 보완이 필요한 것으로 보인다.

• Steel and Composite Structures
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• 제13권3호
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• pp.239-258
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• 2012

In this paper, experimental investigations on high strength steel (HSS) stud connected steel-concrete composite (SCC) girders to understand the effect of shear connector density on their flexural behaviour is presented. SCC girder specimens were designed for three different shear capacities (100%, 85%, and 70%), by varying the number of stud connectors in the shear span. Three SCC girder specimens were tested under monotonic/quasi-static loading, while three similar girder specimens were subjected to non-reversal cyclic loading under simply supported end conditions. Details of casting the specimens, experimental set-up, and method of testing, instrumentation for the measurement of deflection, interface-slip and strain are discussed. It is found that SCC girder specimen designed for full shear capacity exhibits interface slip for loads beyond 25% of the ultimate load capacity. Specimens with lesser degree of shear connection show lower values of load at initiation of slip. Very good ductility is exhibited by all the HSS stud connected SCC girder specimens. It is observed that the ultimate moment of resistance as well as ductility gets reduced for HSS stud connected SCC girder with reduction in stud shear connector density. Efficiency factor indicating the effectiveness of high strength stud connectors in resisting interface forces is estimated to be 0.8 from the analysis. Failure mode is primarily flexure with fracturing of stud connectors and characterised by flexural cracking and crushing of concrete at top in the pure bending region. Local buckling in the top flange of steel beam was also observed at the loads near to failure, which is influenced by spacing of studs and top flange thickness of rolled steel section. One of the recommendations is that the ultimate load capacity can be limited to 1.5 times the plastic moment capacity of the section such that the post peak load reduction is kept within limits. Load-deflection behaviour for monotonic tests compared well with the envelope of load-deflection curves for cyclic tests. It is concluded from the experimental investigations that use of HSS studs will reduce their numbers for given loading, which is advantageous in case of long spans. Buckling of top flange of rolled section is observed at failure stage. Provision of lips in the top flange is suggested to avoid this buckling. This is possible in case of longer spans, where normally built-up sections are used.

• 한국해양학회지:바다
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• 제12권3호
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• pp.219-224
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• 2007

광양만의 순환을 이해하기 위하여 2006년 봄철에 수심이 가장 깊은 두 지점을 선정하여 ADCP가 장착된 모니터링 부표 2대를 이용하여 유속관측을 하였다. 두 지점에서 공통적으로 북향류가 지배적인데, 이는 서쪽의 남향류를 동반하는 반시계 방향의 순환 이 있음을 뒷받침 하고 있다. 남쪽에서는 14 m 수심에서 유향이 반전되는 2층 구조가 뚜렷하며 저층의 북향류는 바닥에 가까운 36 m 수심까지 증가한다. 북쪽 지점에서는 북향류가 더욱 강해져서 북쪽의 단면적 감소에 따른 해류의 가속 효과가 있으며 상층부에서도 북향류가 우세하다. EOF 분석을 통한 연직구조에 있어서 첫 번째 모드는 북쪽 부표에서 전체 분산의 74%인데 비하여 남쪽 부표에서는 67%로 감소하고 상대적으로 2층 구조의 비중이 크다. 반시계 방향의 순환과 관련된 북향류의 전형적인 유속은 약 10 cm/s이다. 여기에 중첩되는 변동성으로서 국지적인 바람의 영향은 거의 받지 않는 반면에 동-서 방향의 바람에 의한 외해의 에크만 수송과 관련된 비국지적 영향은 주로 풍속이 강할 경우에 나타난다.