• 한국농공학회논문집
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• 제55권4호
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• pp.95-106
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• 2013

It is now generally known that dynamical climate modeling outputs include systematic biases in reproducing the properties of atmospheric variables such as, preciptation and temerature. There is thus, general consensus among the researchers about the need of bias-correction process prior to using climate model results especially for hydrologic applications. Among the number of bias-correction methods, distribution (e.g., cumulative distribution fuction, CDF) mapping based approach has been evaluated as one of the skillful techniques. This study investigates the uncertainty of using various CDF mapping-based methods for bias-correciton in assessing regional climate change Impacts. Two different dynamicailly-downscaled Global Circulation Model results (CCSM and GFDL under ARES4 A2 scenario) using Regional Spectial Model for retrospective peiod (1969-2000) and future period (2039-2069) were collected over the west central Florida. Total 12 possible methods (i.e., 3 for developing distribution by each of 4 for estimating biases in future projections) were examined and the variations among the results using different methods were evaluated in various ways. The results for daily temperature showed that while mean and standard deviation of Tmax and Tmin has relatively small variation among the bias-correction methods, monthly maximum values showed as significant variation (~2'C) as the mean differences between the retrospective simulations and future projections. The accuracy of raw preciptiation predictions was much worse than temerature and bias-corrected results appreared to be more significantly influenced by the methodologies. Furthermore the uncertainty of bias-correction was found to be relevant to the performance of climate model (i.e., CCSM results which showed relatively worse accuracy showed larger variation among the bias-correction methods). Concludingly bias-correction methodology is an important sourse of uncertainty among other processes that may be required for cliamte change impact assessment. This study underscores the need to carefully select a bias-correction method and that the approach for any given analysis should depend on the research question being asked.

• 대한방사선기술학회지:방사선기술과학
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• 제39권2호
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• pp.149-156
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• 2016

자기공명영상을 이용한 심장혈류의 측정은 호흡과 심장의 불수의적인 움직임으로 인해 제한되어 왔다. 따라서 본 연구에서는 심장혈류의 측정값을 비교하여 적절한 호흡방법과 영상변수를 제시하고 위상대조도 자기공명영상을 통한 심장혈류검사의 정확성을 향상시키고자 하였다. 연구 대상자는 정상의 지원자 15명(남: 10명, 여: 5명) 평균연령: $30{\pm}5.2$세를 대상으로 하였다. 상행대동맥과 하행대동맥에서 위상대조도 자기공명영상을 이용하여 각각 호흡정지 retrospective 1NEX와 비 호흡정지 retrospective 1-3NEX로 검사하여 비교하여 평가하였다. 연구 결과 상행대동맥에서 호흡정지 retrospective 1NEX의 평균혈류량/평균혈류속도는 각각 $96.17{\pm}19.12ml/sec$, $17.04{\pm}4.12cm/sec$로 비 호흡정지 retrospective 1NEX의 $72.31{\pm}13.27ml$, $12.32{\pm}3.85cm/sec$와는 통계적으로 유의한 차이를 보였다(p<0.05). 반면에 2NEX에서는 평균혈류량과 평균혈류속도가 $101.90{\pm}24.09$, 16.84{\pm}4.32, 3NEX에서는 $103.06{\pm}25.49$, $16.88{\pm}4.19$로 통계적으로 유의한 차이를 보이지 않았다(p>0.05). 하행대동맥에서 호흡정지 retrospective 1NEX의 평균혈류량/평균혈류속도는 $76.68{\pm}19.72ml/sec$, $22.23{\pm}4.8cm/sec$로 비 호흡정지 retrospective 1-3NEX와 비교 시 유의한 차이를 보이지 않았다. 그러므로 비 호흡정지 retrospective방법은 NEX의 증가에 따라 호흡정지 retrospective방법과 비교하여 심장혈류 측정값에 유의한 차이점이 없기 때문에 숨을 잘 참지 못하거나 또는 소아환자에게 있어서 심장혈류 검사의 진단적 가치를 높여줄 것으로 사료된다.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 1994년도 교수 연수회(환경)
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• pp.417-425
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• 1994

Although animal studies have been used most often for quantitative risk assessment, it is generally recognized that well-conducted epidemiologic studies would provide the best basis for estimating human risk. However, there are several features related to the design and analysis of epidemiologic studies that frequently limit their usefulness for quantitating risks. The lack of accurate information on exposure in epidemiologic studies is perhaps the most frequently cited limitation of these studies for risk assessment. However. other features of epidemiologic study design, such as statistical power, length of follow-up, confounding, and effect modification, may also limit the inferences that can be drawn from these studies. Furthermore, even when the aforementioned limitations are overcome, substantial uncertainty exists concerning the choice of an appropriate statistical (or biologic) model for extrapolation beyond the range of exposures observed in a particular study. This paper focuses on presenting a review and discussion of the methodologic issues involved in using epidemiologic studies for risk assessment. This review concentrates on the use of retrospective, cohort, mortality studies of occupational groups for assessing cancer risk because this is the most common application of epidemiologic data for quantitative risk assessment (QRA). Epidemiologic data should not be viewed as a panacea for the problems inherent in using animal bioassay data for QRA. Rather, information that can be derived from epidemiologic and toxicologic studies complement one another, and both data sources need to be used to provide the best characterization of human risk.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제21권1호
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• pp.11-16
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• 2010

This review aimed to assist clinicians in the identification and assessment of adult attention-deficit hyperactivity disorder (ADHD) with an emphasis on diagnostic and rating instruments. Pubmed and RISS were utilized to identify relevant studies and critical reviews on the diagnosis and assessment of adult ADHD, published between 1988 and 2010. The Adult ADHD Self-Report Scale-v1.1, the ADHD Rating Scale-IV, the Conners Adult ADHD Rating Scale, and the Current Symptoms Scale have been utilized for self-reporting of current ADHD symptoms. The Brown ADD Rating Scale, the ADHD Rating Scale-IV, the Current Symptoms Scale, and the Conners Adult ADHD Rating Scale have also been evaluated by an observer. The Childhood Symptom Scale and the Wender-Utah Rating Scale have been used for retrospective assessment of childhood ADHD symptoms and the Adult ADHD Investigator Symptom Rating Scale, the Adult Interview, the Brown ADD Diagnostic Form, the Conners adult ADHD diagnostic interview for DSM-IV, and the Wender-Reimherr Interview have been available as comprehensive diagnostic interviews. There is a wide variety of instruments available with respect to adult ADHD. The choice of appropriate instruments is essential for achieving accurate diagnosis and assessment of this disorder.

• The Journal of Asian Finance, Economics and Business
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• 제6권1호
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• pp.321-328
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• 2019

The purpose of the study is to analyze the main approaches to assessing human capital and develop proposals for its most objective assessment of it at the different levels of manifestation - individual, microeconomic and macroeconomic. The article considers the basic approaches to the evaluation of human capital, used in practice: retrospective (costly) and prospective (income based). Cost based methods involve measuring the value of human capital based on the total costs associated with its formation. The proposed additional evaluation criteria, in particular, the use of the expert approach and the developed indicators of a qualitative assessment of the human capital of the enterprise will allow development that is more efficient and use of available human resources. Human capital is becoming a major factor in the formation and development of an innovative economy and knowledge economy. Accordingly, the proposed additions to the assessment of human capital at the country level are aimed at assessing it from a new angle, taking into account the current global trends in the formation of an innovative economy and digitalization. They meet qualitatively new requirements for human capital as the main productive factor in the creation of new highly efficient technologies that promote the active development of the social sphere, science, education, health, etc.

• 대한감각통합치료학회지
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• 제20권1호
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• pp.14-25
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• 2022

목적 : 본 연구는 두뇌타이밍 능력이 낮은 아동을 대상으로 상호작용식 메트로놈(Interactive Metromome; IM)을 이용한 두뇌타이밍 훈련을 적용한 후 읽기 능력에 미치는 효과를 파악하고자 하였다. 연구방법 : 2019년~2021년에 아동발달연구소에서 IM 훈련을 시행한 아동 중 타이밍 능력이 자신의 연령 평균보다 낮은 아동 8명의 자료를 수집하여 검사 전-검사 후의 변화를 비교하였다. 두뇌타이밍 훈련은 주당 2~3회기, 총 70회기 이상, 회기 당 40~50분으로 아동의 발달적 특성에 따라 적용되었다. 훈련 전후 두뇌타이밍의 변화는 IM의 전체형검사(Long Form Assessment; LFA), 읽기 능력은 기초학습기능 수행평가체제(Basic Academic Skills Assessment:Reading; BASA:R)로 측정하였다. 결과 : LFA의 두뇌타이밍 능력 평가결과 모든 아동의 전체 운동과제의 반응시간이 감소되어 두뇌타이밍 능력이 향상된 것으로 나타났고 통계학적으로도 유의한 차이를 보였다(p<.05). 또한 BASA:R의 읽기 검사와 빈칸채우기 검사의 원점수에서도 유의한 향상을 나타냈다(p<.05). 결론 : 본 연구는 두뇌타이밍 능력이 낮은 아동의 읽기 능력 향상을 위한 두뇌타이밍 훈련의 임상적 근거를 제시하였다는데 그 의의가 있다.

• 한국산업보건학회지
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• 제22권1호
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• pp.1-8
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• 2012

Objectives: The aim of this study is to review occupational hygiene activities, including work environment measurement as required by the industrial safety and health laws of Korea, and suggest improvements required to establish an effective exposure surveillance system. Methods: The controversial limitations of exposure surveillance examining the work-association of several types of cancers in semiconductor workers were reviewed. Results: The bulk of the exposure surveillance system was found to focus purely on work environment measurements without providing other important exposure surrogates, such as job title, operation, exposure duration, etc. The current work environment measurement system is limited in terms of the efficient assessment of the exposure status of workers due to a lack of exposure information. Conclusion: The introduction of a national standard classification of occupations and job titles into the exposure and health effect surveillance system should be discussed in order to retrospectively assess exposure characteristics.

• Advances in Energy Research
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• 제8권1호
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• pp.1-19
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• 2022

The application of Photovoltaic (PV) power in the building sector, is expanding as part of the ongoing energy transition into renewables. The article addresses the question of sustainability of energy generated from PVs through an environmental assessment of a building-integrated PV system (BIPV) connected to the grid through net metering. Employing retrospective life cycle analysis (LCA), with the CCaLC2 software and ecoinvent data, the article shows that the carrying structure and other balance of system (BOS) components are responsible for a three times higher energy payback time than the literature average. However, total environmental impact can be lowered through reuse or reinstallation of PVs on the same building structure after the 30-year interval. Further ways to improve environmental efficiency include identifying the most polluting materials for each LCA parameter. The results of this study are of interest to researchers and producers of PVs and organizations investing and promoting decentralized power production through PVs.

• 보건행정학회지
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• 제26권4호
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• pp.289-304
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• 2016

Background: Rehabilitations in subacute phase are different from acute treatments regarding the characteristics and required resource consumption of the treatments. Lack of accuracy and validity of the Korean Diagnosis Related Group and Korean Out-Patient Group for the acute patients as the case-mix and payment tool for rehabilitation inpatients have been problematic issues. The objective of the study was to develop the Korean Rehabilitation Patient Group (KRPG) reflecting the characteristics of rehabilitation inpatients. Methods: As a retrospective medical record survey regarding rehabilitation inpatients, 4,207 episodes were collected through 42 hospitals. Considering the opinions of clinical experts and the decision-tree analysis, the variables for the KRPG system demonstrating the characteristics of rehabilitation inpatients were derived, and the splitting standards of the relevant variables were also set. Using the derived variables, we have drawn the rehabilitation inpatient classification model reflecting the clinical situation of Korea. The performance evaluation was conducted on the KRPG system. Results: The KRPG was targeted at the inpatients with brain or spinal cord injury. The etiologic disease, functional status (cognitive function, activity of daily living, muscle strength, spasticity, level and grade of spinal cord injury), and the patient's age were the variables in the rehabilitation patients. The algorithm of KRPG system after applying the derived variables and total 204 rehabilitation patient groups were developed. The KRPG explained 11.8% of variance in charge for rehabilitation inpatients. It also explained 13.8% of variance in length of stay for them. Conclusion: The KRPG version 1.0 reflecting the clinical characteristics of rehabilitation inpatients was classified as 204 groups.

• 한국환경보건학회지
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• 제38권4호
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• pp.277-290
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• 2012

Objectives: Diesel engine exhaust (DE) accounts for a significant percentage of air pollutants that are associated with various health outcomes including mortality, asthma, chronic bronchitis, respiratory tract infection, etc. In June, 2012, the International Agency for Research on Cancer (IARC) released the assessment results that classified DE as "carcinogenic to humans" (Group 1). This review is therefore focused on the lung cancer risks of DE. Methods: Literatures were searched using PubMed with key words of "diesel exhaust", "lung cancer", and other related terms for the period between 1990 and 2012. A total of 295 articles were searched and sixteen epidemiologic studies were identified as potentially relevant. Results: Sixteen epidemiologic studies about the lung cancer risks of workers exposed to DE in various occupations were summarized in two tables, 1) retrospective cohort studies and 2) case-control studies. Increased lung cancer risk, although not always smoking adjusted, was observed in 6 out of 8 retrospective cohort studies and 4 of 8 case-control studies. Conclusions: Diesel fuel is widely used in Korea. Exposure to DE is confirmed to be a human carcinogen by IARC. Noncancer health risks of DE also need careful attention as DE is a major source of fine-particle pollution. Along with the efforts for reducing the DE emission through improvements of diesel engines and fuel, and the use of alternative fuels, comprehensive health risk assessment of DE should be conducted to minimize the adverse health effects.