• Journal of Korean Academy of Nursing
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• v.40 no.3
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• pp.326-335
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• 2010

Purpose: The purpose of this descriptive study was to determine the perception of physicians and nurses on family presence during invasive procedures. Methods: The study population consisted of 100 physicians and 100 nurses from five hospitals which have more than 500 beds in B city. Data collection was done from August 20 to September 19, 2007. The Family Presence During Resuscitation (FPDR) Inventory developed by Fulbrook, Albarran and Latour (2005) was used as the study instrument. The collected data was analyzed by t-test, ANOVA and Duncan's multiple range test using SPSS/WIN 14.0 version. Results: Nurses had more positive attitudes to allowing family members to be present during invasive procedures than physicians did. However, compared to physicians, nurses had more concern about problems of confidentiality, arguing with medical team, and increased rate of legal action if family members were present during invasive procedure. Conclusion: The results of this study indicate that educational programs and policy for family presence be required within the hospital to enhance the perception of physicians and nurses to the family presence.

• The Journal of Korean Academic Society of Nursing Education
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• v.14 no.1
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• pp.138-146
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• 2008

Purpose: The first responder's role during a cardiac arrest scene is to initiate CPR. The AHA has recognized and included the first responder's role for improving the survival rate of cardiac arrest patients. Health personnel working in nursing, emergency care, dental hygiene, radiology, and ocular optics frequently confront sudden cardiac arrest while working. This study was to identify the relationship between the educational experience and recognition with the level of knowledge about CPR for college students. Method: Five hundred forty college students enrolled in the department of nursing science, radiological technology, ocular optics, emergency medical technician, or dental hygiene in Daejeon city were surveyed. The tool used was CPR knowledge developed by the authors based on a literature review including 2005 AHA's CPR guideline. Result: The higher educational experience of CPR was, the higher the level of knowledge. The knowledge of the students in nursing or emergency medical technician was higher than students in dental hygiene, radiology, and ocular optics. Conclusion: CPR class should be included in the curriculum for college students in order to improve their accuracy as a first responder to cardiac arresting patients.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2001.11a
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• pp.109-109
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• 2001

The present study was done to investigate the relationship between Kupffer cells and alteration of cytochrome P-450 (CYP)-dependent drug metabolizing enzyme activities during polymicrobial sepsis. Male rats were subjected to polymicrobial sepsis by cecal ligation and puncture (CLP) followed by fluid resuscitation. The gadolinium chloride (GdC1$_3$, 10 mg/kg), blocker of Kupffer cells, was pretreated intravenously at 48 h and 24 h prior to the induction of CLP. All assay parameters were determined at 24 h after CLP or sham operation. In CLP-treated rats, the mortality rate of animals increased to 50% and serum alanine (ALT) and aspartate aminotransferase (AST) levels also significantly elevated. However, this increase was not suppressed by GdC1$_3$ pretreatment. Microsomal lipid peroxidation markedly increased after CLP operation. This increase was significantly attenuated by pretreatment. Total cytochrome P-450 content and NADPH-cytochrome P-450 reductase activity were not changed after CLP operation, but GdC1$_3$pretreatment reduced total cytochrome P-450 content, The hepatic microsomal CYP 1A1, 1A2, 2Bl and 2El activities in CLP-induced rats were also not significantly different from sham-operated rats. However, GdC1$_3$pretreatment showed a moderate increase in CYP1A1 and 1A2 activities. Our findings suggest that Kupffer cells may be partly responsible for producing hepatocellular dysfunction during sepsis.

• The Korean Journal of Physiology and Pharmacology
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• v.3 no.2
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• pp.231-236
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• 1999

This study was performed to examine 1) Whether hypothermic cardiac arrest produces myocardial HSP72 expression; 2) And if, whether it serves to protect the heart against the subsequent hypothermic arrest. In the present study, neonatal rats were placed in an icebath to induce hypothermia. To determine whether hypothermic cardiac arrest produces myocardial HSP72, experimental animals were subjected to 10-min hypothermic insult before the extraction of the heart. The intervals between the insult and extraction were 1 (1 HR), 4 (4 HR), 8 (8 HR), 24 (24 HR) or 72 (72HR) hours. A minimal amount of HSP72 was detected in control, 1 HR and 72 HR groups. In contrast, 8 HR and 24 HR groups showed a significant level of HSP72 expressions. To assess the cardioprotective effect of HSP72 against hypothermic cardiac arrest, we compared the proportion of recovery from the arrest between control and preconditioned (PREC) animals. Control animals were subjected to 20-min hypothermic insult, while PREC group was preconditioned by 10-min hypothermic insult 8 hours before the 20-min test hypothermic insult. Resuscitation rate from cardiac arrest induced by the 20-min hypothermic insult in PREC group was significantly higher than that in controls. These results suggest that the cardioprotective effect of hypothermic preconditioning is associated with an increase in HSP72 expression.

• Journal of The Korean Society of Clinical Toxicology
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• v.3 no.2
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• pp.130-134
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• 2005

Lithium is mainly prescribed for manic and depressive disorder, also frequently prescribed for the other diseases such as migraine, cluster headache, alcoholism, and obsessive-compulsive disorder. An acute lithium intoxication occurs in cases of patients ingesting large amount lithium at a time, a chronic lithium intoxication occurs in patients on chronic lithium therapy. Acute or chronic lithium poisoning occurs frequently in case of patients on chronic lithium therapy ingesting larger dose than prescribed. Manifestations of lithium poisoning are various. It is possible nervous, cardiovascular, renal, gastrointestinal and endocrine systems to be involved. Due to intracellular high concentration, mortality rate is high in acute lithium intoxication patients on chronic lithium therapy. We report a case of acutely intoxicated 40-year-old male on chronic lithium therapy. His chief complaints were deterioration and high fever. On his arrival to an emergency department, he was in cardiac arrest. He restored return of spontaneous circultion (ROSC) 5 minutes later after cardiopulmonary cerebral resuscitation (CPCR) and referred to department of internal medicine for hemodialysis. Vigorous treatment was given to the patient, but he was expired at 4th hospital day.

• Journal of Korean Academy of Nursing Administration
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• v.15 no.1
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• pp.64-71
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• 2009

Purpose: This study shows the prehospital emergency nursing practices, and analyzes them associated with their individual characteristics and job conditions. Method: Based on a survey of the National Emergency Medical Center in Korea(2008), principal components were extracted from 7 prehospital emergency nursing practices by factor analysis, and some regression analyses of principal components(CPR-AED and V/S-I.V.) were executed on individual characteristics and job conditions. Results: The PENs gave themselves higher order ratings for vital sign check, airway management for loss of consciousness patients, CPR for suspicious cardiac arrest, keeping vein open for shock patients, AED for abnormal pulse rate, AED for suspicious cardiac arrest, and AED for loss of consciousness. Age and duty periods were statistically significant influential factors on the CPR-AED component. Conclusion: The results indicate that the PENs were competent in overall prehospital emergency activities and procedures even some weak self-evaluations, and that the standard curriculum and practice standard for prehospital nursing should be developed in order to increase nursing leadership in prehospital emergency settings.

• The Korean Journal of Emergency Medical Services
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• v.19 no.3
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• pp.117-138
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• 2015

Purpose: This study was performed targeted to paramedic and doctors, to examine the frequency, importance, and admissibility of the tasks of paramedics, and to establish as a basis for expanding their business scope. Methods: The subjects were 282 paramedics and 58 doctors, and the study was performed from October 20 to November 19, 2014. The statistical analysis was done by using SPSS/WIN 20.0. Results: The results showed the difference between the legal business scope of paramedics and the actually performed work. The frequently covered areas were trauma, cardiac arrest, and respiratory care; however, severity classifications were the most important. Concerning drug administration, epinephrine administration seemed to be the most necessary. Conclusions: The findings of this study can be used as basic data to broaden the capacity building and business scope of paramedics. Furthermore, to increase the resuscitation rate of emergency patients, the various tasks of paramedics must be incorporated, and these should be supported by laws and institutions.

• The Korean Journal of Emergency Medical Services
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• v.10 no.1
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• pp.71-77
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• 2006

This study is focused on middle school students who are composed of a factor in medical emergency system. In the case of cardiac failure, it is to make its basic data and develop its education program of CPR(cardiopulmonary resuscitation) which can increase the patient's survival rate before his hospitalization. The findings of this study is as follows. The subject of study is composed of 117 persons who are 54 boy-students(46.2%) and 63 girl-students(53.8%) in sex and 72 first-grade students(61.5%) and 45 second-grade students (38.5%) in a school year. In the accuracy degree, the practice of artificial respiration is $42.28{\pm}34.42%$ in case of basic CPR(cardiopulmonary resuscitation). The accuracy degree of the thorax pressure is $82.17{\pm}15.40%.$ In the accuracy degree, the practice of artificial respiration is $92.16{\pm}25.68%$ in boy-students and $20.38{\pm}24.16%$ in girl-students, the second-grade students is $58.40{\pm}33.29%$, which is higher than the first-grade students' $32.21{\pm}31.14%$. In the accuracy degree, the thorax pressure is $92.16{\pm}3.91%$ in boy-studetns and $73.61{\pm}16.41%$ in girl-students. In the accuracy degree of the thorax pressure, the second-grade students are $82.60{\pm}16.54%$ and the first-grade students $81.91{\pm}3.91$, which doesn't show any significant difference in school year. The satisfaction degree after theory & practice education is $2.12{\pm}.85$. In the satisfaction degree of its basic CPR, girl-students are $2.14{\pm}.83$ and boy-students are 2.11. In the satisfaction degree of its basic CPR, the second-grade students are $2.40{\pm}.61$ and the first-grade students are $1.95{\pm}.94$. This study is to lead to some suggestions. First, it is necessary to develop the education program and educate its knowledge & technology in proportion to student's characteristics of sex and school year. Second, education authorities should develop a subject of the accident prevention and first-aid treatment in its curriculum and provide the practical education of CPR for adults, adolescents and children. Third, it is necessary to study the education program as well as the education evaluation of CPR further on.

• The Korean Journal of Emergency Medical Services
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• v.13 no.1
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• pp.97-114
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• 2009

Purpose : This study was performed to identify the knowledge and educational wants for first-aid and its related factors of senior students in elementary schools. Methods : From July 11-25, 2008, this study surveyed 437 elementary school students using a structured questionnaire. Result : Of the study subjects, 47.6% of the subjects had experienced first-aid conditions 25.4% had injuries, 11.0% had indigestion, 10.5% had sprains, 6.2% had acute abdominal pains, 5.9% had brash, and 5.7% had fractures. The experience rates of first-aid conditions were significantly different according to gender, mothers' educational status, means of school attendance and amount of exercise. The experience rate of first-aid education was 71.4%. There was a significant difference with grade, and school reports. They had education about cardiopulmonary resuscitation (52.5%), injury treatment and desmology(48.7%) in a good order. The score of knowledge about first-aid was $13.95{\pm}4.1$ and it was converted on the basis of 100 points, the results were below 50points, and there was a significant difference in grades. Educational wants for first-aid was 64.3%, and as a result of multi-logistic regression analysis of characteristics relating to educational wants, there was a significant difference between gender, grade, mothers' educational status, and amount of exercise. Conclusion : The rate of first-aid experience of elementary school students was high, but as their recognition and knowledge on first-aid was low, the importance of first-aid education and educational wants should be reflected for practical and organized education.

• Journal of Korean Biological Nursing Science
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• v.6 no.2
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• pp.57-68
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• 2004

The contrast medium is very commonly used in more than 90% of computed tomography(CT) scans. It is difficult to predict the occurrence of adverse reactions and the degree of adverse reactions are diverse from mild urticaria, itching, nausea, vomiting to even cardiopulmonary arrest. The purpose of this study was to evaluate the symptoms, occurrence rate and risk factors of the adverse reactions in patients after contrast injection during CT examinations. Two hundreds sixty-five patients showed symptoms of adverse reactions out of 71,117 adult patients who received intravenous contrast administration during CT scans from January 2003 to December 2003 at a general hospital. Data was collected by reviewing adverse reaction records and electronic medical record. The results of this study were as follows; 1. Adverse reactions occurred in 265 out of a total of 71,117 patients(0.37%). Clinical symptoms of adverse reactions were most commonly dermatologic problems such as urticaria(69.81%) and itching(63.02%), followed by dyspnea(14.34%), dizziness(11.70%), nausea(6.79%), and vomiting(7.17%). 2. Anaphylactoid reactions occurred in 47 out of a total of 265 patients, and their pattern of symptoms were most commonly related to cardiovascular system(90.91%), followed by respiratory system(82.22%), gastrointestinal system(51.72%), and dermatologic system(16.51%). Eleven patients were transferred to emergency room for further treatment and two patients needed cardiopulmonary resuscitation. 3. The adverse reactions were significantly more common in women than in men(0.46% vs.0.32%, p=.003) and in type D contrast medium than the others(p<.001). The occurrence rate of adverse reactions was not significantly different according to the age and infusion speed of the contrast medium.