• Bulletin of the Korean Chemical Society
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• v.35 no.7
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• pp.1944-1950
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• 2014

Employment of a time consuming, sophisticated calculation using the all-atom force field and generalized-Born implicit solvent model (GBIS) for refinement of NMR structures has become practical through advances in computational methods and capacities. GBIS refinement improves the qualities of the resulting NMR structures with reduced computational times. However, the contribution of GBIS to NMR structures has not been sufficiently studied in a quantitative way. In this paper, we report the effects of GBIS on the refined NMR structures of ubiquitin (UBQ) and GB1 with subsets of distance restraints derived from experimental data. Random omission prepared a series of distance restraints 0.05, 0.1, 0.3, 0.5, and 0.7 times smaller. For each number, we produced five different restraints for statistical analysis. We then recalculated the NMR structures using CYANA software, followed by GBIS refinements using the AMBER package. GBIS improved both the precision and accuracy of all the structures, but to varied levels. The degrees of improvement were significant when the input restraints were insufficient. In particular, GBIS enabled GB1 to form an accurate structure even with distance restraints of 5%, revealing that the root-mean-square deviation was less than 1 ${\AA}$ from the X-ray backbone structure. We also showed that the efficiency of searching the conformational space was more important for finding accurate structures with the calculation of UBQ with 5% distance restraints than the number of conformations generated. Our data will provide a meaningful guideline to judge and compare the structural improvements by GBIS.

• Health Policy and Management
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• v.8 no.2
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• pp.191-215
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• 1998

This descriptive correlational study was done to identify ICU nurses' intention to use restraints and related factors using Ajzen and Madden(1986)'s Theory of Planned Behavior. Self-reported questionnaires were used to measure intention and related factors. The subjects of this study were 287 ICU nurses in 21 general hospitals with at least 200 beds at Taegu, Pusan and Kyungbuk area in Korea. The results of this study were : 1. There were significant differences in intention according to age and marnital status, attitude according to educastion(with indirect measure), subjective norm according to career in ICU(with both measures), perceived behavioral control according to age and career in ICU(with direct measure), and knowledge according to education and position. 2. There were significant correlations among intention and all factors. Intention was correlated with attitude(r=.2119), subjective norm(r=.1112), and perceived behavioral control(r=.3448) with direct measure. Attitude was correlated with subjective norm(r=.2530), perceived behavioral control(r=.3005), and knowledge(r=.1388) with direct measure. Subjective norm was correlated with perceived behavioral control(r=.1321) with direct measure. Intention was correlated with attitude(r=.1496) and perceived behavioral control(r=.2922) with indirect measure. Attitude was correlated with subjectivenorm(r=.2829) and knowledge(r=-.1390) with indirect measure. Also, subjective norm was correlated with perceived behavioral control(r=.2363) with indirect measure. 3. ICU nurses' intention to use restraints was explained 16.7% by perceived behavioral control, attitude with direct measure, control belief, and age. By this study, it was foundr that ICU nurses reported high level of intention to use restraints. The most important predictor of intention to use restraints was perceived behavioral control toward using restrains, which reflected the easiness and difficulty in the use of restraints.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.5
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• pp.452-458
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• 2016

This is a descriptive study on visiting caregivers' perception of restraint use. Data were collected from 113 caregivers working at long-term facilities using a structured questionnaire from Feb to March 2016. The caregivers' perception of restraint use was the medium score. The items they considered the most important reasons for the restraints was "Protecting an older person from falling out of bed", which was primarily intended to prevent accidents of the elderly. The score of the knowledge of restraint use was 11.23 points out of 18 and those affected were more than 50 years of age. The attitude score to the use restraints was 9.19, and caregivers thought it should be possible to refrain from using restraints. Work experience of 3 years or less were higher. The perception of using restraints is affected by the knowledge and attitudes of restraint use. This is very important for the elderly in long-term care facilities and is related to health and human rights. Therefore, it is important to provide continuous education related to the use of restraints and regulations on their management.

• Journal of Digital Convergence
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• v.14 no.9
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• pp.495-504
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• 2016

The purpose of this study was conducted to investigate the perception and attitude toward physical restraints among elderly care workers. The subjects were 153 care workers who are working at elderly care facilities within the regions. Data were collected by structured questionnaires. Collected data were analyzed using descriptive statistics, t-test, ANOVA, $Scheff{\acute{e}}$ test and Pearson Correlation Coefficient. The mean score of the perception for physical restraints was 2.83 out of 5, and the mean score of the attitude for the physical restraints was 3.56 out of 5. There was a statistically significant positive correlation between the perception and attitude about physical restraints (r=.31, p<.001). This research has confirmed that it is necessary for care workers to have education about low score items of recognition and attitude about physical restraints. Therefore, we need to develop proper and efficient educational program about use method for physical restraints, and need to develop guideline for adopting physical restraints. Also, we should make efforts and attentions to reduce or abolish physical restraints in order to protect the elderly human rights.

• Korean Journal of Adult Nursing
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• v.25 no.2
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• pp.148-156
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• 2013

Purpose: The purpose of this study was to investigate the emotional response of family members of physically restrained patients in the intensive care units (ICUs). Methods: The study subjects were 200 family members of ICU patients who had been on physical restraints in two university hospitals. Data were collected using the "Instrument of family's emotional response toward physically restrained patients". Results: The mean score of familial emotional response was 2.69 out of a possible 5. The subcategory of acceptance was the highest with 3.56 points followed by depression (3.02), helplessness (2.94), anxiety (2.87), shock (2.74), avoidance (2.64), and grudge (2.08). Multiple stepwise regression analysis indicated that the age of family members, side effects of restraints, and information provision were the variables influencing on negative emotional response of family. Conclusion: Family members showed slightly negative emotional response toward the physical restraints. This finding could be influenced by their limited knowledge of the need for the restraints. Educational programs or fact sheets to be given to family members may be helpful.

• Journal of Auto-vehicle Safety Association
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• v.4 no.2
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• pp.5-10
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• 2012

Whiplash is the most frequent injury among occupants in low speed rear-end car collision. The aim of this paper is to analyze thecorrelation between influence parameters of head restraints and whiplash injury criteria.In this paper, DFSS (Design for Six Sigma) method is used for optimum design of head restrains. Four control factors of head restraints have selected by function matrix method. The effects of the control factors have been experimentally evaluated by using a sled pulse from 16km/h relative velocity which is suggested by KNCAP (Korean New Car Assessment Program). In order to reduce the noise factors of dynamic tests, whiplash tests were repeated twice. By using DFSS, the correlation between control factors and injury criteria has been comprehended.

• Transactions of the Korean Society of Automotive Engineers
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• v.14 no.6
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• pp.179-183
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• 2006

Whiplash injuries of the neck are one of the most common injuries reported from automotive rear impacts. Whiplash injuries can be reduced by changing geometry of head restraint. Therefore, geometries of head restraint were evaluated according to the test procedures of the Korea New Car Assessment Program(KNCAP) to improve safety of head restraint. In this study, nine vehicle's head restraints were tested. As the test results, one head restraints is rated at "Marginal", three head restraints are rated at "Acceptable" level, and the last five head restraints are rated at "Good" level.

• The Korean Journal of Rehabilitation Nursing
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• v.19 no.2
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• pp.118-127
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• 2016

Purpose: This study was to develop an evidence-based clinical practice protocol of physical restraints by adaptation process for patients with a geriatric hospital. Methods: Protocol adaptation process was conducted in accordance with manual for guideline adaptation version 1.0 by ADAPTE collaboration. Results: The adapted physical restraint protocol was consisted of 3 domains and 37 recommendations. The number of recommendations in each domain were: 7 nursing assessment, 19 nursing intervention, and 11 nursing evaluation. More than half (56.8%) of the recommendations were rated as grade B, 37.8% as grade C, and 5.4% were rated as grade D. Conclusion: The adapted physical restraint protocol is expected to contribute as an evidence-based clinical practice protocol for healthcare workers in geriatric hospitals for reducing and improving efficiency of appropriate physical restraints use.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.4
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• pp.529-537
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• 2021

Although the use of physical restraints is controversial, it is still commonly used in hospitalized patients to prevent patient accidents in clinical practice. It is, therefore, necessary to evaluate the knowledge, attitude, perception, and nursing practices related to the use of physical restraints. This was a cross-sectional descriptive study in which self-administered questionnaires were collected from 144 nursing students at two Universities. Descriptive statistics, including t-test, one-way ANOVA, Pearson correlation coefficients, and multiple regression, were applied to analyze the data collected. Our results reveal that the mean knowledge score of nursing students regarding the use of physical restraints was 11.55±2.81, the mean attitude score was 60.01±7.24, the mean perception score was 59.97±10.68, and the mean nursing practice score was 38.04±4.15. Significant positive correlations were observed between nursing practice and knowledge, attitude, and perception. Multiple regression analysis showed that the factors significantly related to nursing practice and the use of physical restraints were perception (β=.23, p=.005) and attitude (β=.21, p=.009), having a total explained variance of 13.0%. The findings from this study suggest that perception is the strongest predictor of the use of physical restraints in nursing practice. Thus, it is necessary to develop and apply an evidence-based educational intervention program to ensure that nursing students correctly understand the need for physical restraints and later use them appropriately in clinical practice.

• The Korean Journal of Emergency Medical Services
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• v.22 no.2
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• pp.7-22
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• 2018

Purpose: This study aimed to investigate recognition, attitudes, knowledge, education experience, and education demand regarding physical restraint among laypersons. Methods: A self-reported questionnaire was completed by 105 randomly recruited laypersons in D city. Excluding 2 incomplete answers, 103 data were analyzed by frequency analysis, t-test, ANOVA, and chi-square test using SPSS 23.0. Results: Laypersons' recognition of physical restraints was rated at 3.37 out of 5 points, and showed a positive perspective. Knowledge on physical restraints was rated at 13.68 out of 18 points and was affected by age and education level (F = 2.845, p = .028)(F = 3.126, p = .029) A majority of the participants had no education on physical restraints. Nevertheless, participants showed intention to receive education in physical restraint to reach further understanding. Conclusion: Education on physical restraints is necessary for lay persons. However, there were education limits for people living in modern times. As an intervention addressing this problem, observing videos on the internet is recommended. Moreover, for advertising/educational purposes, accessing the internet and using smart-phone applications are suggested.