• Journal of Korean Society for Quality Management
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• v.42 no.2
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• pp.235-251
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• 2014

Purpose: To develop efficient PL response system, SMEs should decide which component of PL response system is important and implemented with priority under limited resources. To accomplish this goal, we propose strategic priority components of PL response system for SME manufacturer. Methods: We categorize the components of PL response system based on prior research results - System, Organization, Training, Technology, Cost, and Awareness. AHP (Analytic Hierarchy Process) is applied to extract important components of PL response system, which is used in assigning the priority of component. To analyze effects of each components, performance sensitivity analysis is applied. Results: The survey analysis results show Technology is the most important components. Organization and Cost component are follows. As the importance of Technology is changed, we can find Organization, Cost is second and third important components. Conclusion: Our research shows Technology which is related to make a safe product with systematic process, is a basic enabler of PL response system. Also, building a PL team and securing a budget for PL activity should be carry out with limited resources.

• Journal of Korean Society of Forest Science
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• v.104 no.4
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• pp.536-542
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• 2015

This study was examined for the growth response of tree diameter and volume to thinning treatments from different thinning intensities using three long-term thinning trials for Japanese Evergreen Oak (Quercus acuta Thunb.) stands in Wando island, Korea. After thinning in 1999, annual tree growth of diameter and volume was highest in heavy thinned stands for individual tree and this growth pattern of thinning response showed similar tendency to the individual tree growth response in light thinned stands. By increasing diameter growth, the value of H/D ratio (HDR) as an indicator of stem form was properly decreased and improved up to 80%. Although there is significant growth response of basal area in both heavily and lightly thinned stands, the growth potential both of heavily and lightly thinned stands in total stand volume is not likely to reach at the level of unthinned stands because of basal area growth loss associated with both light and heavy thinnings.

• Journal of the Korean Society of Safety
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• v.37 no.3
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• pp.71-78
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• 2022

The purpose of this study is to improve the National Fire Mobilization Plan. This plan is a national-level comprehensive response system aimed to compensate for scarce firefighting resources and minimize damage from large-scale disasters that exceed the response limits of city and province firefighting forces. As such, relevant literature and domestic and foreign firefighting mobilization standards were reviewed, and simulations of firefighting mobilization were performed using the QGIS program to compare and analyze cases. Results showed that, as opposed to the current method of issuing mobilization orders by dividing resources according to city and province, recognizing the entire country as a single entity and prioritizing the mobilization of adjacent firefighting resources is more effective in terms of minimizing time and distance and more quickly securing resources. Regarding national firefighting mobilization, recognizing the country's firefighting resources as a whole will allow adjacent firefighting resources to be mobilized with priority. However, the mobilization-related limits of each region need to be set to respond to local disasters. Once the scale of mobilization is determined, a system that can quickly calculate how to mobilize firefighting resources based on location and distance can be established. Additionally, it is necessary to create an integrated management system so the central government can directly organize and mobilize local firefighting resources.

• Proceedings of the Korea Water Resources Association Conference
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• 2002.05b
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• pp.1223-1229
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• 2002

• Proceedings of the Plant Resources Society of Korea Conference
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• 2023.04a
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• pp.17-17
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• 2023

Chrysanthemum zawadskii (C. zawadskii) is used in traditional East Asian medicine for the treatment of various diseases, including inflammatory disease. However, it has remained unclear whether extracts of C. zawadskii inhibit inflammasome activation in macrophages. The present study assessed the inhibitory effect of an ethanol extract of C. zawadskii (CZE) on the activation of the inflammasome in macrophages and the underlying mechanism. Bone marrow[-derived macrophages (BMDMs) were obtained from wild-type C57BL/6 mice. The release of IL-1β and lactate dehydrogenase in response to nucleotide-binding oligomerization domain-like receptor (NLR) family pyrin domain containing 3 (NLRP3) inflammasome activators, such as ATP, nigericin and monosodium urate (MSU) crystals, was significantly decreased by CZE in lipopolysaccharide(LPS)-primed BMDMs. Western blotting revealed that CZE inhibited ATP-induced caspase-1 cleavage and IL-1β maturation. To investigate whether CZE inhibits the priming step of the NLRP3 inflammasome, we confirmed the role of CZE at the gene level using RT-qPCR. CZE also downregulated the gene expression of NLRP3 and pro-IL-1β as well as NF-κB activation in BMDMs in response to LPS. Apoptosis associated speck-like protein containing a caspase-recruitment domain (CARD) oligomerization and speck formation by NLRP3 inflammasome activators were suppressed by CZE. By contrast, CZE did not affect NLR family CARD domain containing protein 4 (NLRC4) or absent in melanoma 2 (AIM2) inflammasome activation in response to Salmonella typhimurium and poly(dA:dT) in LPS-primed BMDMs, respectively. The results revealed that three key components of CZE, namely linarin, 3,5-dicaffeoylquinic acid and chlorogenic acid, decreased IL-1β secretion in response to ATP, nigericin and MSU. These findings suggest that CZE effectively inhibited activation of the NLRP3 inflammasome.

• The Plant Pathology Journal
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• v.30 no.2
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• pp.136-150
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• 2014

Although multiple transcription factors (TFs) have been characterized via mutagenesis to understand their roles in controlling pathogenicity and infection-related development in Magnaporthe oryzae, the causal agent of rice blast, if and how forkhead-box (FOX) TFs contribute to these processes remain to be characterized. Four putative FOX TF genes were identified in the genome of M. oryzae, and phylogenetic analysis suggested that two of them (MoFKH1 and MoHCM1) correspond to Ascomycota-specific members of the FOX TF family while the others (MoFOX1 and MoFOX2) are Pezizomycotina-specific members. Deletion of MoFKH1 (${\Delta}Mofkh1$) resulted in reduced mycelial growth and conidial germination, abnormal septation and stress response, and reduced virulence. Similarly, ${\Delta}Mohcm1$ exhibited reduced mycelial growth and conidial germination. Conidia of ${\Delta}Mofkh1$ and ${\Delta}Mohcm1$ were more sensitive to one or both of the cell cycle inhibitors hydroxyurea and benomyl, suggesting their role in cell cycle control. On the other hand, loss of MoFOX1 (${\Delta}Mofox1$) did not show any noticeable changes in development, pathogenicity, and stress response. Deletion of MoFOX2 was not successful even after repeated attempts. Taken together, these results suggested that MoFKH1 and MoHCM1 are important in fungal development and that MoFKH1 is further implicated in pathogenicity and stress response in M. oryzae.

• Plant Resources
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• v.7 no.1
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• pp.77-86
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• 2004

The reduced ratio of red:far-red (R:FR) light acts as a measure of the proximity of competitors and plants can detect the potentially competing neighbor plants by perceiving reflected R:FR signals and initiate the response of “shade avoidance” before actual shading occurs. The phytochrome system is responsible for monitoring the changes in the R:FR and initiating the shade avoidance response. The response to low R:FR ratio was studied in a white aspen Populus alba clone ‘Bolleana’ using two filter systems: a clear plastic filter system that allows a R:FR ratio less than 1.0 to pass from adjacent border plant reflection; and a special commercial plastic that blocks FR light and creates a R:FR ratio above 3.0. The reduced R:FR signals enhanced the stem elongation in response to competition at the expense of relative stem diameter growth. Trees grown inside clear chambers were 27 ％ taller than trees grown inside the FR-blocking filter chambers. Stem taper of clear chamber trees was 16％ less than the FR-blocking filter trees. Low R:FR also induced 22％ more stem dry weight and 13％ greater petiole length per leaf compared to the FR-blocking filter trees. There were no statistically significant differences in leaf area, leaf number increment, and total dry weight between the two light filter treatments.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.13 no.6
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• pp.2824-2837
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• 2019

Container technologies are widely used in infrastructures to deploy and manage applications in cloud computing environment. As containers are light-weight software, the cluster of cloud applications can easily scale up or down to provide Internet-based services. Container-based applications can well deal with fluctuate workloads by dynamically adjusting physical resources. Current works of scheduling applications often construct applications' performance models with collected historical training data, but these works with static models cannot self-adjust physical resources to meet the dynamic requirements of cloud computing. Thus, we propose a self-adaptive automatic container scheduling framework AutoScale for cloud applications, which uses a feedback-based approach to adjust physical resources by extending, contracting and migrating containers. First, a queue-based performance model for cloud applications is proposed to correlate performance and workloads. Second, a fuzzy Kalman filter is used to adjust the performance model's parameters to accurately predict applications' response time. Third, extension, contraction and migration strategies based on predicted response time are designed to schedule containers at runtime. Furthermore, we have implemented a framework AutoScale with container scheduling strategies. By comparing with current approaches in an experiment environment deployed with typical applications, we observe that AutoScale has advantages in predicting response time, and scheduling containers to guarantee that response time keeps stable in fluctuant workloads.

• Journal of the Korean Society of Food Culture
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• v.34 no.6
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• pp.779-784
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• 2019

The purpose of this study was to optimize the rice protein extracted using a response surface methodology. The experiment was designed based on a CCD (Central Composite Design), and the independent variables were the high pressure (X₁, 0-400 MPa) and processing time (X₂, 0-10 minutes). The results of the extraction content (Y₁), residue content (Y₂), and recovery yield (Y₃) were fitted to a response surface methodology model (R²= 0.92, 0.92, and 0.93, respectively). Increasing the pressure and processing time has a positive effect on the extraction content (Y₁), residue content (Y₂), and recovery yield (Y₃). Therefore, these high-pressure conditions (independent variables) can significantly affect the improvement in rice protein extraction efficiency. Thus, the optimal conditions of X₁ and X₂ were 400 MPa and 10 min., respectively. Under these optimal conditions, the predicted values of Y₁, Y₂, and Y₃ were 62.93, 57.53 mg/g, and 91.76%, respectively.

• Journal of the Korean Society of Food Culture
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• v.34 no.5
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• pp.637-644
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• 2019

The purpose of this study was to optimize the mandarin dry chip manufacturing using a response surface methodology. The experiment was designed based on a CCD (Central Composite Design), and the independent variables were the drying temperature ($X_1$, $50-90^{\circ}C$), drying time ($X_2$, 12-36 hours), and microwave pretreat time ($X_3$, 0-4 minutes). The results of appearance ($Y_5$), color ($Y_6$), taste ($Y_8$) and overall acceptance ($Y_{10}$) were fitted to the response surface methodology model ($R^2=0.86$, 0.88, 0.89, and 0.84, respectively). Increasing the drying temperature and microwave treatment time were negatively evaluated for consumer acceptance. On the other hand, a high value of consumer acceptance was evaluated when the drying time was more than 24 hr. Therefore, the optimal conditions of $X_1$, $X_2$, and $X_3$ were $52.989^{\circ}C$, 24 hr, and 1 min, respectively. Under these optimal conditions, the predicted values of $Y_5$, $Y_6$, $Y_8$, and $Y_{10}$ were 5.066, 5.338, 5.063, and 5.339, respectively.