• Nuclear Medicine and Molecular Imaging
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• 제43권5호
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• pp.369-385
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• 2009

In this paper, the authors intended to summarize briefly the features of lymphoma with regard to $^{18}F$-FDG PET for assessment of tumor response to therapy, to describe why assessment of treatment response should be performed, to review what method so far has been used in monitoring treatment response, to discuss what limitations of morphologic imaging criteria for assessing tumor response are, in compared with $^{18}F$-FDG PET, and to introduce recently proposed criteria for assessing tumor response in malignant lymphoma. And also the authors emphasize the need to understand the characteristics of diagnostic performance of $^{18}F$-FDG PET in several clinical settings in order to interpret $^{18}F$-FDG PET results appropriately, and to encourage the use of interval likelihood ratio to enhance clinical implications of test results which, in turns, allows referring physicians to understand the meaning of interpretation with easy. Until recently, treatment response has been assessed according to the morphologic criteria. Metabolic imaging with $^{18}F$-FDG PET was adopted to have important role for treatment assessment in IWC+PET criteria proposed recently by IHP. To accomplish this role, we should perform and interpret $^{18}F$-FDG PET according to IWC+PET criteria. It is important for referring physicians to understand the various limitations of $^{18}F$-FDG PET and pitfalls in PET interpretation, and to understand that clinical information are needed by nuclear medicine physicians to optimize the interpretation of $^{18}F$-FDG PET.

• 한국농공학회논문집
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• 제65권5호
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• pp.13-24
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• 2023

Due to recent climate change, the amount of rainfall during the summer season in South Korea has been decreasing, leading to an increase in areas affected by frequent droughts. Droughts have the characteristic of occurring over a wide area and being unpredictable in terms of their onset and end, necessitating proactive research to cope with them. In this study, we conducted an assessment of agricultural drought vulnerability in Taean-gun, Chungcheongnam-do, focusing on irrigation facilities and paddy fields. The assessment criteria were meteorological impact, drought occurrence status, supplementary water supply capacity, and drought response capability, with nine specific indicators selected. The drought response capability was analyzed by applying a scoring system as a key component of the agricultural drought vulnerability assessment, while the other indicators were quantified using an entropy weighting technique. The results of the assessment showed that Anmyeon-eup and Taean-eup were the safest areas, while Wonbuk-myeon, Nam-myeon, and Gonam-myeon were the most vulnerable. It is expected that the findings can be utilized to enhance understanding and proactive measures for coping with agricultural drought, and to determine the priority of drought response in different regions.

• 한국식품위생안전성학회지
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• 제19권1호
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• pp.19-24
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• 2004

미생물 위해성 평가의 용량-반응 모델은 생물학적 모델과 경험적 모델로 나눌 수 있다. 생물학적 모델은 미생물의 분포형태, 미생물에 대한 숙주의 감수성, 감염을 일으킬 수 있는 미생물 수에 대한 가정을 바탕으로 성립된 모델로서, 대표적으로 Exponential model과 $\beta$-Poisson model이 있다. 경험적 모델은 주로 화학물질의 독성을 나타내는데 이용되어 온 모델로, Weibull-Gamma model등이 있다. 여러 용량-반응 모델 중에서 실험 데이터에 적합한 모델을 걱정하는 데에는 deviance function(Y)을 이용하며, 현재 일부 식중독균에 대해서는 사람과 실험동물에서의 용량-반응 모델이 연구되어 있다.

• Steel and Composite Structures
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• 제35권4호
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• pp.527-544
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• 2020

This research presents the design and numerical assessment of composite steel-concrete frame structures with welded dissipative fuses. The assessment has been carried out based on linear response spectrum, nonlinear static pushover and time history procedures. The analytical expressions which define the envelope of the nonlinear response of the dissipative fuses are first presented and calibrated against experimental results available in literature. The assessment is then carried out according to a design methodology proposed herein. Outcomes of the numerical assessment indicate that the use of welded dissipative fuses successfully limited damage within the replaceable parts. Furthermore, although structures with dissipative fuses present lower strength and, generally, lower displacement capacity, their displacement ductility and global dissipative performance are generally higher than conventional structures, especially when the structure with dissipative fuses presents a dissipative configuration adjusted to the bending moment distribution diagram calculated for the applied seismic action.

• 환경영향평가
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• 제6권2호
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• pp.17-28
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• 1997

• 한국재난관리표준학회지
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• 제1권1호
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• pp.63-67
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• 2008

본 연구는 위험성 분석 기법을 통해 화학 산업 시설에서 발생 가능한 화학 테러에 대한 원인 을 규명하고, 기존의 테러 대응 방법에 대한 분석 및 평가를 함으로써 효과적 대응 개선 방안을 마련하기 위 한 프로그램 개발이다 테러 위험성 평가 프로그램은 자산 분석(Asset Characterization), 위협 평가(Threat Assessment), 취약성 분석(Vulnerability Analysis), 위험성 평가(Risk Assessment), 대응책 제시(New Countermeasure)의 총 5단계의 순차적 알고리즘으로 구성되어 있다. 개발된 프로그램을 항만에 위치한 석유 저장 및 정제 공정에 적용하여 테러 위험성과 그 원인을 분석함으로써 위험성 평가 프로그램의 효용성과 신뢰성을 검증하였다. 화학 산업 시설에서의 보안 및 테러리즘에 대한 문제성 제기를 통해 그 해결책을 제시하고 테러의 취약점과 원인을 규명함으로써 테러나 재해(extreme event) 발생 시 효과적인 대응책 마련이나 대응 전략 수립에 기여하고자 개발된 프로그램이다.

• 한국과학교육학회지
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• 제22권1호
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• pp.122-131
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• 2002

본 연구는 수행 평가 방식의 중요성이 대두됨에 따라 실지로 수행형 평가 문항이 전통적인 선다형 평가문항에 비해 어떤 학생들에게 어떻게 유용한지를 분석한 연구이다. 이를 위하여 제 3차 수학 과학 성취도 국제비교 반복 연구에 사용된 선다형과 수행형 평가문항들을 내용영역별로 분석하여, 수행형의 평가문항과 선다형의 평가문항의 효율성을 비교 분석하였다. 자료분석 결과 수행형의 문항이 선다형의 문항에 비하여 학생들의 능력을 더 정확하게 추정함으로써 효율성이 높은 것으로 나타났다. 특히 환경이나 과학의 본성 영역에 비하여 지구과학, 생물, 물리와 화학 영역에서 수행형의 문항이 선다형의 문항에 비하여 학생들의 능력을 더 정확하게 추정하고 있음을 보여주었다. 또한 선다형의 문항에 비하여 적은 수의 문항으로 학생들의 능력을 추정함에도 불구하고 추정오차가 적어, 적은 수의 수행형 문항으로도 학생들의 능력을 정확하게 추정할 수 있음을 시사하고 있다.

• Environmental Analysis Health and Toxicology
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• 제23권4호
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• pp.231-245
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• 2008

Various methods for detecting changes in response behaviors of indicator specimens are presented for monitoring effects of toxic treatments. The movement patterns of individuals are quantitatively characterized by statistical (i.e., ANOVA, multivariate analysis) and computational (i.e., fractal dimension, Fourier transform) methods. Extraction of information in complex behavioral data is further illustrated by techniques in ecological informatics. Multi-Layer Perceptron and Self-Organizing Map are applied for detection and patterning of response behaviors of indicator specimens. The recent techniques of Wavelet analysis and line detection by Recurrent Self-Organizing Map are additionally discussed as an efficient tool for checking time-series movement data. Behavioral monitoring could be established as new methodology in integrative ecological assessment, tilling the gap between large-scale (e.g., community structure) and small-scale (e.g., molecular response) measurements.

• International journal of advanced smart convergence
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• 제10권4호
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• pp.117-123
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• 2021

This study aims to analyze working hours of sprinkler heads when a fire occurs at an indoor gymnasium while sprinkler heads are installed in division of standard response type, special response type, and earlier response type. The fire scenario was designed under the assumption that the fire started from overheating of a heater in the indoor gymnasium has transferred on to a couch to spread. The analysis on the operation time of the standard response type sprinkler head, the special response type sprinkler head and the early response sprinkler head was conducted. The result showed that, in case of fire in a gymnasium, the time for opening of the heat sensor due to the heat from the fire varies by the type of the sprinkler head. When a special response type sprinkler is installed, it worked below the assessment standards. When an early response sprinkler head is installed, it worked appropriately according to assessment standards. Based on the results, we found that sprinkler heads will work properly when installed according to design relevant to laws and regulations. This means that there is a limit in installation of sprinkler heads based on the existing law-based design as for indoor gymnasiums. Again, we conclude that if sprinkler heads are installed based on design made through laws and regulations, more time will be needed for operation, making it highly likely to fail to stop a fire at an earlier point of time.

• Nuclear Engineering and Technology
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• 제53권3호
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• pp.967-973
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• 2021

In 2011, an earthquake and subsequent tsunami hit the Fukushima Daiichi Nuclear Power Plant, causing simultaneous accidents in several reactors. This accident shows us that if there are several reactors on site, the seismic risk to multiple units is important to consider, in addition to that to single units in isolation. When a seismic event occurs, a seismic-failure correlation exists between the nuclear power plant's structures, systems, and components (SSCs) due to their seismic-response and seismic-capacity correlations. Therefore, it is necessary to evaluate the multi-unit seismic risk by considering the SSCs' seismic-failure-correlation effect. In this study, a methodology is proposed to obtain the seismic-response-correlation coefficient between SSCs to calculate the risk to multi-unit facilities. This coefficient is calculated from a probabilistic multi-unit seismic-response analysis. The seismic-response and seismic-failure-correlation coefficients of the emergency diesel generators installed within the units are successfully derived via the proposed method. In addition, the distribution of the seismic-response-correlation coefficient was observed as a function of the distance between SSCs of various dynamic characteristics. It is demonstrated that the proposed methodology can reasonably derive the seismic-response-correlation coefficient between SSCs, which is the input data for multi-unit seismic probabilistic safety assessment.