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A Review of Dose-response Models in Microbial Risk Assessment  

최은영 (농촌진흥청 농업과학기술원 농촌자원개발연구소)
박경진 (한국보건산업진흥원)
Publication Information
Journal of Food Hygiene and Safety / v.19, no.1, 2004 , pp. 19-24 More about this Journal
Abstract
Dose-response models in microbial risk assessment can be divided into biologically plausible models and empirical models. Biologically plausible models are formed by the assumptions in dose distribution of microbes, host sensitivity to microbes, and minimal infectious dose of microbes : there are Exponential model and $\beta$-Poisson model, representatively. Empirical models are mainly used to express the toxicity of chemicals : there are Weibull-Gamma model etc. Deviance function (Y) is used to fit available data to dose-response models, and some dose-response models for food-borne pathogens are developed in humans and experimental animals.
Keywords
dose-response model; microbial risk assessment; food-borne pathogen;
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