• 컴퓨터교육학회논문지
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• 제15권6호
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• pp.33-41
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• 2012

본 논문은 온라인 평가 문항 관리 시스템 및 방법에 관한 것이다. 제안하는 시스템은 학습자 정보 데이터베이스, 영역별, 난이도별로 분류된 문항을 저장하는 문제 은행 데이터베이스로 구성된다. 문제은행 데이터베이스는 특정 학습자 또는 특정 학습에 대한 문항을 선택하는 문항 선제부, 특정 학습자 또는 특정 학습에 대한 문제지를 제작하는 문제지 제작부, 문제지를 저장하였다가 온라인 테스트를 수행할 때 출력하는 문제지 은행 데이터베이스를 포함한다. 학습자가 온라인 테스트에 제출된 문항들에 대한 문항 선택순서, 보기 선택순서, 클릭회수, 반응시간에 대한 평가 데이터를 수집하는 온라인 테스트부, 및 온라인 테스트부로부터 수집된 학습자의 온라인 테스트 평가 데이터를 분석하여 학습자의 학습수준과 학습능력, 성향을 평가하고 진단하여 보고하는 반응패턴 분석부를 포함한다. 제안하는 시스템은 보기 선택순서, 클릭회수, 반응시간을 학습자의 평가결과에 반영하여 효율적으로 학습자의 학습수준과 학습능력, 성향을 평가하고 진단할 수 있다.

• 한국식품위생안전성학회지
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• 제14권4호
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• pp.319-326
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• 1999

최근 국내에서는 Escherichia coli O157:H7, Listeria monocytogenes등의 미생물에 대한 건강위해성이 강조되면서 미생물 위해성평가에 대한 필요성이 제기되고 있고, U.S.FPA, U.S.DA, FAO/WHO를 비롯한 국제기구 및 외국 유관기관들에서도 미생물 위해성평가 방법을 식품관리에 활용하고자 방법론 연구에 주력하고 있다. 미생물 위험성은 화학물질과 달리 인체건강에 대한 영향이 즉각적이고, 심각하게 나타나 정량적인 위해성평가가 용이하지 않고 유해화학물질과는 다른 평가방법이 요구된다. 식품중 미생물의 위해성평가는 크게 4단계로 구분되는데, 미생물관련질환 추세파악 및 미생물 관련질병에 관한 역학조사 등을 활용하는 위험성확인 단계와 실제 식품원료, 식품가공, 수송, 포장단계 중 식품의 물리적, 화학적 조건에 따른 미생물 변화를 고려하여 식품중 미생물에 대한 노출을 정량화하는 노출평가 단계, 미생물의 용량에 따른 질병발생에 근거하여 용량-반응관계를 규명하는 용량-반응평가 단계, 규명된 모델을 활용하여 모든 평가결과를 통합함으로 위해 도치 예측과 불확실성 분석 등을 수행하는 위해도결정단계로 구성되어 있다. 미생물 용량-반응평가는 크게 비역치(Nonthreshold)와 역치(Threshold) 평가 방법론으로 구분되는데, 비역치 평가방법론은 단일 병원균이 감염을 일으킬 수 있다는 것과 감염을 일으킬 수 있는 확률이 독립적이라는 가정을 전제로 하고, 역치평가방법론은 미생물이 감염을 일으키기 위해서 각기 개별 역치가 존재하는데 어느 정도의 미생물수가 모여 서로 작용해야 독성유발물질을 만들어 낸다는 가정을 전제로 한다. 현재 받아들여지고 있는 비역치 모델로는 Exponential, Beta-poisson, Gompertz, Gamma-weibull 모델 등이 있으며, 역치모델로는 Log-normal, Log-logistic모델 등이 있다. 본 연구에서는 인체 volunteer자료를 활용하여 용량-반응자료를 입력하고 용량-반응자료를 토대로 적합한 수학적 모델을 찾아내어, 선별한 모델의 적합도 검정을 실시하는 방법론 연구를 실시하였으며, 노출평가 자료와 용량-반응평가 결과를 연계하여 위해도를 결정하는 과정에 대해 연구하였다 이 밖에도 모델(Food MicroModel)을 이용하여 식품의 염도, 수분활성도, 온도, pH등의 조건에 따른 미생물의 성장률, 사멸률 등 변화를 예측할 수 있는 방법론 연구를 통해 식품의 최적 보관 조건등을 찾아내는 방법을 습득하였다. 미생물 위해성평가는 외국에서도 아직 초기 연구단계에 있으며 현재로서 사후조사자료인 역학자료보다 건강한 성인남자를 대상으로 한 volunteer 자료를 우선적으로 활용하고 있으나 노약자나 민감그룹에 대한 실험은 현실적으로 불가능하여 동물실험을 이용한 평가방법을 연구중에 있다. 추후 연구방향으로는 국내 volunteer들을 대상으로 한 미생물별 용량-반응결과를 토대로 population sensitivity를 비교할 수 있는 기초자료를 확보함으로써 미생물에 대한 인구집단의 반응 민감성 차이를 비교하고 시료채취 후 즉각적인 실험실적 분석이 가능토록하여 정확한 인체노출평가를 수행함으로써 미생물 위해성평가방법론을 식품미생물관리에 적용하는 것이다.

• Smart Structures and Systems
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• 제2권2호
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• pp.127-140
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• 2006

In this study, a wavelet-based covariance-driven system identification technique is proposed for damage assessment of structures under ambient excitation. Assuming the ambient excitation to be a white-noise process, the covariance computation is shown to be able to separate the effect of random excitation from the response measurement. Wavelet transform (WT) is then used to convert the covariance response in the time domain to the WT magnitude plot in the time-scale plane. The wavelet coefficients along the curves where energy concentrated are extracted and used to estimate the modal properties of the structure. These modal property estimations lead to the calculation of the stiffness matrix when either the spectral density of the random loading or the mass matrix is given. The predicted stiffness matrix hence provides a direct assessment on the possible location and severity of damage which results in stiffness alteration. To demonstrate the proposed wavelet-based damage assessment technique, a numerical example on a 3 degree-of-freedom (DOF) system and an experimental study on a three-story building model, which are all under a broad-band excitation, are presented. Both numerical and experimental results illustrate that the proposed technique can provide an accurate assessment on the damage location. It is however noted that the assessment of damage severity is not as accurate, which might be due to the errors associated with the mode shape estimations as well as the assumption of proportional damping adopted in the formulation.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 1994년도 교수 연수회(환경)
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• pp.426-430
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• 1994

The assessment of exposure is an important component of the risk assessment process. Exposure information is used in risk assessment in at least two ways: 1) in the identification of hazards and the epidemiologic research investigating exposure-response relationships and 2) in the development of population exposure estimates. In both of these cases, the value of a chemical risk assessment is enhanced by improvements in the quality of exposure assessments. The optimum exposure assessment is the direct measurement of population exposure; however, such measurements are rarely available. Recent developments in methods for exposure assessment allow estimates to be made that are valid representations of actual exposure. The use of these exposure estimates to classify exposures correctly enhances the likelihood that causal associations between exposure and response will be correctly identified and that population risks will be accurately assessed.

• 한국안전학회지
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• 제29권5호
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• pp.116-122
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• 2014

Assessment of setting process of concrete is important as it provides useful information to schedule concreting work in construction site. Electrical impedance measurement method, which utilizes the change of electrical resistance of concrete, has been applied to assess setting process of cement-based materials. However, the applicability of the method has been demonstrated only for cement paste and mortar. The main purpose of this research is to develop the electrical impedance based setting process assessment for concrete. To this end, electrical impedance response model for concrete should be developed in advance since it is essential to estimate the electrical resistance of concrete from measured impedance response. The electrical resistance of concrete is a key parameter for the setting process assessment. In this study electrical impedance responses of the concrete in setting process are measured and analyzed. Thereby, an electrical impedance response model of the liquid state concrete is developed and schematically validated.

• 한국항공운항학회지
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• 제29권1호
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• pp.38-46
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• 2021

The Organization's ability to respond to social disasters has begun to be treated as important through social shock situations that have never been experienced, such as COVID-19. Among them, the ability to respond to unexpected risks and resilience is emerging. Since social disasters such as infectious diseases are periodically repeated, compounded, and enlarged, they develop into a global crisis situation, so this crisis response capability is treated as national competitiveness. Therefore, this study aims to improve the organization's response capability in terms of risk response and resilience under rapid social disasters such as COVID-19. The aviation safety field was taken as an example. From the Safety-II perspective, safety management focuses on the ability to resilience in response to system vulnerabilities in various situations. In this study, I intend to apply RAG(Resilience Assessment Grid) of Respond, Monitor, Learn and Anticipate, the four major potential of resilience engineering. Based on Hollnagel's research, potential elements were classified into four, and items were organized through an expert panel using Delphi techniques. The final configured RAG items are 15 Respond, 15 Monitor, 15 Learn and 11 Anticipate. The RAG was evaluated by 42 experts in the field of aviation safety.

• 한국산업보건학회지
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• 제22권3호
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• pp.175-183
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• 2012

Objectives: This study developed a harmonized method for risk assessment based on the Hazard & Risk Evaluation of Chemicals (HREC) according to the Industrial Safety and Health Act (ISHA). Methods: Three preliminary studies, performed during 2010 and 2011 by the Occupational Safety and Health Research Institute and three academic research groups, were compared. The differences in risk assessment, especially in the dose-response assessment method, were analyzed. A new harmonized method for dose-response assessment was suggested and its applicability for the HREC was examined. Results: Considering the various steps of each dose-response assessment, the equivalent steps in quantitative correction, uncertainty factor 2 (UF2) for intra-species uncertainty, and UF3 for the experimental period in the uncertainty correction were relatively high. Using our new method, the total correction values (quantitative correction plus uncertainty correction) ranged from 72~15,789 to 30~60, and the ratio of the threshold limit value (TLV) to the reference concentration decreased from 12.8~1900 to 5.4~11.8. Furthermore, when we performed risk characterization by our new method, hazard quotient (HQ) values for chloroethylene, epichlorohydrin, and barium sulfate became 3.0, 14.1, and 1.13 respectively, whereas three previous studies reported HQ values of 7.1, 4580, and 87.3 considering reasonable maximum exposure (RME) conditions. HQs of the three chemicals were calculated to be 0.6, 2.4, and 0.1 respectively, when compared to their TLVs. Conclusions: Our new method could be applicable for the HREC because the total correction values and the ratio of TLVs were within reasonable ranges. It is also recommended that additional risk management measures be applied for epichlorohydrin, for which the HQ values were greater than 1 when compared with both reference values and the TLV. Our proposed method could be used to harmonize dose-response assessment methods for the implementation of risk assessment based on the HREC according to ISHA.

• Tuberculosis and Respiratory Diseases
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• 제80권2호
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• pp.136-142
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• 2017

Assessing response to therapy allows for prospective end point evaluation in clinical trials and serves as a guide to clinicians for making decisions. Recent prospective and randomized trials suggest the development of imaging techniques and introduction of new anti-cancer drugs. However, the revision of methods, or proposal of new methods to evaluate chemotherapeutic response, is not enough. This paper discusses the characteristics of the Response Evaluation Criteria In Solid Tumor (RECIST) version 1.1 suggested in 2009 and used widely by experts. It also contains information about possible dilemmas arising from the application of response assessment by the latest version of the response evaluation method, or recently introduced chemotherapeutic agents. Further data reveals the problems and limitations caused by applying the existing RECIST criteria to anti-cancer immune therapy, and the application of a new technique, immune related response criteria, for the response assessment of immune therapy. Lastly, the paper includes a newly developing response evaluation method and suggests its developmental direction.

• 한국수학교육학회지시리즈A:수학교육
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• 제43권2호
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• pp.151-162
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• 2004

For the past several years, performance assessment has been widely used by mathematics teachers. The superiority of performance assessment items compare to multiple choice items has been discussed by many researchers, however these discussions tend to be lack of empirical data. Thus, this study aims to examine the effectiveness of tree response items in comparison with multiple choice items. Using the information function in Item Response Theory(IRT), item information of free response items and multiple choice items from the Third International Mathematics and Science Study-Repeat(TIMSS-R) were obtained and compared. Test informations of the whole mathematics area as well as each content area of mathematics were computed. On average, tree response items yielded more information than multiple choice items, especially in measurement and data interpretation. This study also revealed that free response items estimated students' mathematics ability more accurately than multiple choice items with smaller number of items.

• Korean Journal of Radiology
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• 제23권11호
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• pp.1089-1101
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• 2022

Immunotherapy has revolutionized and opened a new paradigm for cancer treatment. In the era of immunotherapy and molecular targeted therapy, precision medicine has gained emphasis, and an early response assessment is a key element of this approach. Treatment response assessment for immunotherapy is challenging for radiologists because of the rapid development of immunotherapeutic agents, from immune checkpoint inhibitors to chimeric antigen receptor-T cells, with which many radiologists may not be familiar, and the atypical responses to therapy, such as pseudoprogression and hyperprogression. Therefore, new response assessment methods such as immune response assessment, functional/molecular imaging biomarkers, and artificial intelligence (including radiomics and machine learning approaches) have been developed and investigated. Radiologists should be aware of recent trends in immunotherapy development and new response assessment methods.