• Proceedings of the KOSOMBE Conference
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• v.1991 no.05
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• pp.18-21
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• 1991

In this paper, the effect of background grey levels on the visual perception of target image displayed on CRT monitor has been investigated. The purpose of this study is to investigate the efficacy of CRT monitor as a display medium of image information especially in medical imaging field. Three sets of experiments have been performed in this study; the first was to measure the luminance response of CRT monitor and to find the best fitting equation, and the second was the psychophysical experiment measuring the threshold grey level difference between the target image and the background required for visual discrimination for various background grey levels, and the third was to develop a visual model that is predictable of the threshold grey level difference measured in the psychophysical experiment. The result of psycophysical experiment shows that the visual perception performance is significantly degraded in the range of grey levels lower than 50, which is turned out due to the low luminance change of CRT monitor in this range while human eye has been adapted to relatively bright ambient illumination.

• Toxicological Research
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• v.18 no.1
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• pp.99-106
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• 2002

The United States Environmental Protection Agency (EPA) characterized the cancer hazard of di(2-ethylhexyl)-phthalate (DEHP) as a B2 group (probable human carcinogen) and proposed "Guide-lines for Carcinogen Risk Assessment". This guidelines proposed alternative methods for analyzing carcinogen dose-response data and for extrapolating the effects of observed at high dose to predict that might occur at lower doses relevant to human exposure. This proposed guidelines state that "If in a particular case, the evidence indicated a threshold, as in the case of carcinogenicity being secondary to another toxicity that has a threshold, the margin of exposure analysis for toxicity is the same as is done for a non-cancer endpoint". DEHP is excellent candidate for reconideration under the new guidelines for carcinogen risk assessment (John Doull et al., 1998). This study is conducted about risk assessment for infant exposure on DEHP in powdered milk wing methodology in EPA's new guideline on carcinogenic risk assessment. Estimated cancer risk of DEHP in powdered milk and cow milk is 2.83$\times$$10^5$ (using cancer potency: 1.4$\times$$10^2$/ (mg/kg/day)) as mean and MOE is 12075 (using selected NOEL 20 mg/kg/day) as mean. mg/kg/day) as mean.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.30 no.9
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• pp.566-571
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• 2017

A soft baking process was used to enhance the electrical characteristics of solution-processed indium-zincoxide (IZO) thin-film transistors (TFTs). We demonstrate a stable soft baking process using a hot plate in air to maintain the electrical stability and improve the electrical performance of IZO TFTs. These oxide transistors exhibited good electrical performance; a field-effect mobility of $7.9cm^2/Vs$, threshold voltage of 1.4 V, sub-threshold slope of 0.5 V/dec, and a current on/off ratio of $2.9{\times}10^7$ were measured. To investigate the static response of our solutionprocessed IZO TFTs, simple resistor load type inverters were fabricated by connecting a resistor (5 or $10M{\Omega}$). Our IZO TFTs, which were manufactured using the soft baking process at a baking temperature of $120^{\circ}C$, performed well at the operating voltage, and are therefore a good candidate for use in advanced logic circuits and transparent display backplanes.

• The Korean Journal of Physiology
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• v.28 no.2
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• pp.113-122
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• 1994

The present study was carried out to characterize the functional properties of spinomesencephalic tract (SMT) neurons in the lumbar spinal cord of urethane anesthetized rats. Extracellular single unit recordings were made from neurons antidromically activated by stimulation of the midbrain area, including the deep layers of superior colliculus, periaqueductal gray and midbrain reticular formation. Recording sites were located in laminae I-VII of spinal cord segments of L2-L5. Receptive field properties and responses to calibrated mechanical stimulation were studied in 78 SMT cells. Mean conduction velocity of SMT neurons was $19.1{\pm}1.04\;m/sec$. SMT units were classified according to their response profiles into four groups: wide dynamic range (58%), deep/tap (23%), high threshold (9%) and low threshold (3%). A simple excitatory receptive field was found for most SMT neurons recorded in superficial dorsal horn (SDH). Large complex inhibitory and/or excitatory receptive fields were found for cells in lateral reticulated area which usually showed long after-discharge. Most of SMT cells received inputs from $A{\delta}$ and C afferent fiber types. These results suggest that sensory neurons in the rat SMT may have different functional roles according to their location in the spinal cord in integrating and processing sensory inputs including noxious mechanical stimuli.

• Biomedical Science Letters
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• v.4 no.1
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• pp.35-42
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• 1998

The effects of CRP purified from human ascites fluid on phagocytic activity of the human macrophage were investigated. CRP was purified using affinity chromatography including absorption on p-diazonium phosphocholine or C-polysaccharide coupled sepharose 4B and gel filtration on hydroxylapatite column chromatography. Macrophage was separated ficoll hypaque gradient density and absorption method, and then was confirmed phagocytic uptake test using latex method. CRP was able either to inhibit or to enhance phagocytic activity of human macrophage against bacteria in vitro. The effects of CRP on phagocytic activity of human macrophage were in time and dose-dependent manners. The additional sequence of reaction mixture against bacteria in vitro shows a threshold stimulus on the activation of phagocytic response upon the CRP.

• Journal of Biomedical Engineering Research
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• v.14 no.1
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• pp.63-72
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• 1993

In this paper, the effect of background grey levels on the visual perception of target image displayed on CRT monitor has been investigated. The purpose of this study is to investigate the efficacy of CRT monitor as a display medium of image Information especially in medical imaging field. Tllree sets of experiments have been performed in this study : the first was to measure the luminance response of CRT monitor and to find the best fitting equation, and the second was the psychophysical experiment measuring the threshold grey level differences between the target image and the background required for visual discrimination (or various background grey levels, and the third was to develop a visual model that is predictable of the threshold grey level difference measured in the psychophysical experiment. The result of psycophysical experiment shows that the visual perception performance is significantly degraded in the range of grey levels lower than 50, which is turned out due to she low luminance change of CRT monitor in this range while human eye has been adapted lo relatively bright ambient illumination. And it Is also shown in the simulation study using the developed visual model that the dominant factor degrading the visual performance is the reflected light from the monitor surface by ambient light in general illumination condition.

• Structural Monitoring and Maintenance
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• v.5 no.1
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• pp.51-65
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• 2018

A number of sensing techniques have been implemented for detecting defects in civil infrastructures instead of onsite human inspections in structural health monitoring. However, the issue of faults in sensors has not received much attention. This issue may lead to incorrect interpretation of data and false alarms. To overcome these challenges, this article presents a deep learning-based method with a new architecture of Stateful Long Short Term Memory Neural Networks (S-LSTM NN) for detecting sensor fault without going into details of the fault features. As LSTMs are capable of learning data features automatically, and the proposed method works without an accurate mathematical model. The detection of four types of sensor faults are studied in this paper. Non-stationary acceleration responses of a three-span continuous bridge when under operational conditions are studied. A deep network model is applied to the measured bridge data with estimation to detect the sensor fault. Another set of sensor output data is used to supervise the network parameters and backpropagation algorithm to fine tune the parameters to establish a deep self-coding network model. The response residuals between the true value and the predicted value of the deep S-LSTM network was statistically analyzed to determine the fault threshold of sensor. Experimental study with a cable-stayed bridge further indicated that the proposed method is robust in the detection of the sensor fault.

• The Korean Journal of Physiology and Pharmacology
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• v.7 no.6
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• pp.369-373
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• 2003

This study was performed to test whether endomorphin-1 has analgesic effect, when locally administrated into inflamed peripheral tissue. Carrageenan suspension (0.5%) was injected intraplantarly into the right paw of Sprague-Dawley male rats, and the rats were subjected to a series of mechanical stimuli with von Frei filaments before and after the injection. Carrageenan-injected rats showed typical inflammatory hyperalgesic signs and decrease of withdrawal threshold, peaked at 3 to 6 hours after the injection and lasted more than 3 days. Endomorphin-1 was intraplantarly injected with carrageenan, simultaneously or 3∼4 hours after carrageenan. Simultaneous injection of endomorphin-1 with carrageenan significantly reduced hyperalgesia and thd analgesic effect was prolonged up to 8 hours. The delivery of endomorphin-1 ($50{\mu}g$) into the inflamed area after 3 to 4 hours of carrageenan injection significantly increased the threshold of hyperalgesic mechanical withdrawal response, but only partially. Intrathecal treatment of endomorphin-1 completely reversed carrageenan-induced hyperalgesia. This report is the first to show that peripherally delivered endomorphin-1 relieved inflammatory hyperalgesia. But a control through peripheral ${\mu}-opioid$ receptors appears to be not sufficient for complete pain treatment.

• The Korean Journal of Physiology
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• v.21 no.1
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• pp.79-90
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• 1987

The present experiment was performed in 35 normal male volunteers to evaluate the effect of electroacupuncture on the human nociception more clearly and to demonstrate the effect of different parameters of electrical stimulation through acupuncture needles. The threshold of the pain(Tp) and the nociceptive flexion reflex(Tr), the threshold for intolerable pain(Tip) and that for obtaining maximal reflex response(Tmr) were studied before and after electroacupuncture performed on the acupoints of tsusanli and hsuanchung. 1) For the pricking pain, electroacupuncture with intermittent stimulation induced a significant decrease in Tp which recovered after removal of the needles. There was no significant change in other thresholds. 2) For the dull pain, electroacupuncture with intermittent stimulation produced a significant increase in Tp which continued after removal of the needles. But there was no signifcant change in Tip. Electroacupuncture with continuous stimulation induced a slight increase in Tp. 3) After resting without electroacupuncture, Tp and Tip of the dull pain were slightly decreased. These results suggest that electroacupuncture had no significant analgesic effect on the pricking pain induced by electrical stimulation of the foot skin. However, electroacupuncture with intermittent stimulation had significant analgesic effect on the weak dull pain and it had slightly greater analgesic effect than electroacupuncture with continuous stimulation.

• Smart Structures and Systems
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• v.17 no.3
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• pp.413-429
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• 2016

The recent research on proper orthogonal decomposition (POD) has revealed the linkage between proper orthogonal modes and linear normal modes. This paper presents an investigation into the modal identifiability of an instrumented cable-stayed bridge using an adapted POD technique with a band-pass filtering scheme. The band-pass POD method is applied to the datasets available for this benchmark study, aiming to identify the vibration modes of the bridge and find out the so-called deficient modes which are unidentifiable under normal excitation conditions. It turns out that the second mode of the bridge cannot be stably identified under weak wind conditions and is therefore regarded as a deficient mode. To judge if the deficient mode is due to its low contribution to the structural response under weak wind conditions, modal coordinates are derived for different modes by the band-pass POD technique and an energy participation factor is defined to evaluate the energy participation of each vibration mode under different wind excitation conditions. From the non-blind datasets, it is found that the vibration modes can be reliably identified only when the energy participation factor exceeds a certain threshold value. With the identified threshold value, modal identifiability in use of the blind datasets from the same structure is examined.