• Industry Promotion Research
• /
• v.6 no.4
• /
• pp.23-30
• /
• 2021

This study is a study on the satisfaction of the living conditions of the residents of Chungcheongnam-do, and the analysis data was based on the results of the Chungcheongnam-do social survey conducted in 2020 by Statistics Korea. The results of the analysis on the satisfaction of the living conditions of the residents of Chungnam Province are summarized as follows. The level of satisfaction with the quality of life of the living environment, which is a personal characteristic, was 5.92 out of 10 for the degree of satisfaction with one's life, and 6.28 out of 10 for the overall value of the work one is doing. The overall life satisfaction of the region (city and gun) was analyzed as 5.81 out of 10, indicating that the satisfaction of Chungnam residents was more than average. In addition, satisfaction with the residential housing environment was analyzed with the highest frequency and ratio of 43.5%, with 226 people being slightly satisfied. Satisfaction with facility use was also slightly higher in 231 people, showing 44.5% response rate, and slightly higher in women than in men. This study is meaningful in that it provides basic data such as policy implications for improving the quality of life by grasping the social interests related to the quality of life and the subjective consciousness of the people of Chungnam.

• Journal of the Society of Disaster Information
• /
• v.17 no.4
• /
• pp.674-683
• /
• 2021

Purpose: The purpose of this study is to examine the changes in the pattern of crimes caused by the spread and slowdown of coronavirus infections and to devise preventive and countermeasures against various crimes in the future. Method: In order to find out the characteristics of each crime in the non-face-to-face and face-to-face environment, the results of previous prior research and data officially released by the National Police Agency and the prosecution office were compared and analyzed. Result: In the early epidemic of infectious diseases, overall crime has decreased, and civil life-related crimes and crimes targeting the socially disadvantaged are increasing. In the second half of the infectious disease, unlike the first half, the prolonged corona caused the economic recession and unemployment, deepening the damage from illegal private finance and significantly increasing illegal gambling game crimes. Conclusion: According to the time of the outbreak of the COVID-19 pandemic, the quarterly crime characteristics showed that there was a difference in crime type and crime increase and decrease rate, and that crime response measures should be changed accordingly.

• Korean Journal of Organic Agriculture
• /
• v.28 no.4
• /
• pp.615-626
• /
• 2020

The objective of present experiment was to examine the impact of different organic nitrogen (N) fertilizer application rates and different harvesting periods on the forage yield and feed value of kenaf (Hibiscus cannabinus L.). This study was carried out from May to September 2019, the amount of 80 kg of kenaf seed/ha were applied with different rates of nitrogen fertilizer. The plants were sampled at 10 days intervals (100, 110, 120, and 130 days after seeding) from different harvesting dates. In the organic fertilizer treatments, the highest dry matter (DM) yield was observed in the application rate at 250 kg of N/ha. Crude protein (CP) content in leaves was similar between the organic fertilizer rates at 200 and 250 kg of N/ha and were higher compared with other fertilizer treatments. The highest CP content in the stem was 4.3% in the organic fertilizer application rates st 250 kg of N/ha. Neutral detergent fiber (NDF) in leaves showed no significant difference between the chemical fertilizer rates at 200 and 250 kg of N/ha, and the organic fertilizer rates at 150 and 250 kg of N/ha. In addition, DM yield of kenaf was highest in the harvest of 100 days after seeding, and tended to decreased significantly with increase of harvesting periods (p<0.05). As the growth progressed, the plant height and stem ratio increased but the leaves ratio decreased significantly (p<0.05) and the highest was found at 110 days after seeding. The highest CP, Acid detergent fiber (ADF), NDF and total digestible nutrient (TDN) contents in leaves were 13.9, 25.4, 40.5 and 71.1%, respectively that were affected by different harvesting periods. Also, the ADF and NDF in stem increased significantly with increase of kenaf maturity (p<0.05). In conclusion, the optimal organic fertilizer application rates and the proper harvesting periods for the forage yield and quality of kenaf were at 200 to 250 kg of N/ha, and 100 to 110 days after seeding, respectively.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.22 no.4
• /
• pp.25-36
• /
• 2021

This study analyzed the causes of flood accidents, such as isolation and lost footing accidents in Dorimcheon, to provide legal and institutional improvements. For cause analysis, Field Investigation, Stakeholder Interview, Report, manual, Law et al. Review, Analysis of water level change characteristics, automatic alarm issuance standard level analysis, and evacuation time according to river control were evaluated. Dorimcheon has the characteristics of a typical urban river, which is disadvantageous in terms of water control. In addition, the risk of flood accidents is high because the section where fatal accidents occur forms sharply curved channels. Tripping and isolation accidents occur in the floodplain watch and evacuation stage, which is the stage before the flood watch and warning is issued. Because floodplain evacuation is issued only when the water level rises to the floodplain, an immediate response according to the rainfall forecast is essential. Furthermore, considering that the rate of water level rise is up to 2.62 cm/min in Sillimgyo 3 and Gwanakdorimgyo, sufficient evacuation time is not secured after the floodplain watch is issued. Considering that fatal accidents occurred 0.46 m below the standard water level for the flood watch, complete control is very important, such as blocking the entry of rivers to prevent accidents. Based on these results, four improvement measures were suggested, and it is expected to contribute to the prevention of Tripping and Isolation Accidents occurring in rivers.

• Journal of Marine Life Science
• /
• v.4 no.2
• /
• pp.91-95
• /
• 2019

The changes of plasma cortisol concentration to high water temperature on common carp, Cyprinus carpio were studied. 20℃, 24℃ and 28℃ groups showed significantly increased plasma cortisol levels until 6 hours, and decreased plasma cortisol levels after 24 hours. Cortisol levels of 20℃ and 24℃ groups decreased to values close to the cortisol content before the experiment. However, 32℃ group showed significantly increased plasma cortisol levels until 24 hours, and maintained plasma cortisol level until 48 hours. The Cumulative mortality rates of 20℃, 24℃ and 28℃ groups increased until 12 hours, and maintained until 48 hours. Cumulative mortality rate of 32℃ group increased continuously until the end of the experiment. Using the results of this study, it could be used as a method to confirm the risk of mass perish in a specific area through hormone analysis.

• Journal of Breast Cancer
• /
• v.21 no.4
• /
• pp.382-390
• /
• 2018

Purpose: PIK3CA mutation is considered to be a possible cause for resistance to neoadjuvant chemotherapy (NAC) in human epidermal growth factor receptor 2 (HER2)-positive breast cancer. We investigated the association between PIK3CA mutations and the outcome of NAC in HER2-positive breast cancers. Methods: A total of 100 HER2-positive breast cancer patients who had undergone NAC and surgery between 2004 and 2016 were examined. Mutation status was sequentially assessed in pre-NAC, post-NAC, and recurrent specimens taken from these patients. Results: PIK3CA mutations were identified in the sequential specimens of 17 patients (17.0%). These 17 patients experienced shorter disease-free survival (DFS) than the rest of the patients (58.3 months vs. 119.3 months, p=0.020); however, there was no significant difference in pathologic complete response (pCR) and overall survival (OS) (pCR, 17.6% vs. 33.7%, p=0.191; OS, 84.5 months vs. 118.0 months, p=0.984). While there was no difference in pCR between the wild-type and mutant PIK3CA groups in pre-NAC specimens (25.0% vs. 31.8%, p=0.199), PIK3CA mutations correlated with lower pCR in postNAC specimens (0.0% vs. 24.3%, p<0.001). Multivariate analysis revealed significantly worse DFS in the mutant PIK3CA group than in the wild-type group (hazard ratio, 3.540; 95% confidence interval, 1.001-12.589; p=0.050). Moreover, the DFS curves of the change of PIK3CA mutation status in sequential specimens were significantly different (p=0.016). Conclusion: PIK3CA mutation in HER2-positive breast cancer was correlated with a lower pCR rate and shorter DFS. These results suggest that PIK3CA mutation is a prognostic marker for NAC in HER2-positive breast cancer, especially in post-NAC specimens.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.20 no.3
• /
• pp.513-519
• /
• 2019

Typically, contaminated sediments cause clogging of the drain pipe, which increases the residual water pressure in the drain pipe; this study constructed a system for improving drainage efficiency of tunnels by reducing physical and chemical obstructions through ultrasonic energy generated by a PVDF film. The developed hybrid drainage system utilized a PVDF material film fused with an existing drainage tunnel and maintenance system resulting in the ability to initialize the reverse piezoelectric effect, which was evaluated through an on site application. In order to investigate the maintenance performance of the tunnel drainage system, contaminated sediments were simulated in a drainage pipe to test the effect of ultrasonic conditions on drainage efficiency in the laboratory. As a result of applying the developed portable equipment, the ultrasonic energy was generated for about 20 minutes resulting in a reduction of 74.62% of the contaminated sediments and improving drainage efficiency. From the tunnel, acoustic pressure measurements were taken to calculate the response rate while taking into account the laboratory results. In addition, PVDF film was attached to the transverse and longitudinal side of the drainage pipes where contaminated sediments occur most often in the field tunnel. these calculations show contaminant removal was 90% effective.

• Korean Journal of Clinical Laboratory Science
• /
• v.50 no.4
• /
• pp.470-476
• /
• 2018

Facial motor evoked potential (FMEP) by multi-pulse transcranial electrical stimulation (mpTES) can complement free-running electromyography (EMG) and direct facial nerve stimulation to predict the functional integrity of the facial nerve during cerebello-pontine angle (CPA) tumor surgery. The purpose of this paper is to examine the standardized test methods and the usefulness of FMEP as a predictor of facial nerve function and to minimize the incidence of facial paralysis as an aftereffect of surgery. TES was delivered through electrode Mz (cathode) - M3/M4 (anode), and extracranially direct distal facial muscle excitation was excluded by the absence of single pulse response (SPR) and by longer onset latency (more than 10 ms). FMEP from the orbicularis oris (o.oris) and the mentalis muscle simultaneously can improve the accuracy and success rate compared with FMEP from the o.oris alone. Using the methods described, we can effectively predict facial nerve outcomes immediately after surgery with a reduction of more than 50% of FMEP amplitude as a warning criterion. In conclusion, along with free-running EMG and direct facial nerve stimulation, FMEP is a useful method to reduce the incidence of facial paralysis as a sequela during CPA tumor surgery.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.11
• /
• pp.182-190
• /
• 2018

Many pharmaceutical companies operate the SFA system to support salespeople. The SFA system is used for various behaviors of salespeople. However, there is a lack of empirical analysis on the performance of SFA in Korea. The purpose of this study is to investigate the utilization of SFA system and the non - financial performance of SFA system. The subjects of the survey were 347 pharmaceutical community members who consisted of pharmaceutical salespeople and surveyed online for 18 days from March 13, 2018 to April 30, 2018. and the effective response rate was 23.1% (80/347). The analysis shows that the higher the level of SFA system utilization, the higher the non - financial performance. By type of company, the utilization level of multinational companies was higher than that of domestic companies. Among the SFA utilization level items, 1.47 points (3.65, 2.18) were higher than the domestic companies in terms of the support service items. Among the SFA performance items, foreign companies were 1.47 points (3.16, 1.69) Respectively. This suggests that the SFA development and operation method of the domestic company focuses on the management service rather than the support service for the salesperson and the customer satisfaction. Through this study, it is considered that domestic companies should strengthen sales person support and customer satisfaction information providing function when operating SFA system.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.32 no.3
• /
• pp.58-76
• /
• 2019

Objectives : This study was designed to examine the effects of Daecheonglyong-tang(DCL) on atopic dermatitis induced by DNCB in mice Methods : The Nc/Nga mice were divided into 5 groups, and four groups excluding the normal group were applied by 2,4-dinitrochlorobenzene(DNCB), to cause AD and were orally administered with distilled water(negative control), dexamethasone(positive control), and DCL 200 or 400mg/kg once a day for 4 weeks respectively. The visual changes on skin, changes in skin tissue thickness and eosinophil infiltration were observed. IgE, Histamine, Cytokines, immune cells and the amount of gene expression of filaggrin, VEGF, $TGF-{\beta}1$, EGF were measured. Results : Dermatitis score showed a gross improvement on all DCL groups, similar to or better than positive control. All DCL groups showed no significant change in the basophils, while neutrophils and eosinophils decreased. In only DCL 400 mg/kg groups, white blood cells and mononuclear cells were decreased and lymphocytes were increased. In particular, neutrophils had similar or better effects than the positive control. In all DCL groups, IgE, Histamine, $IL-1{\beta}$, IL-4, IL-5, IL-6 and $TNF-{\alpha}$ were decreased and IL-2 was increased. In only DCL 400 mg/kg groups, IL-10 decreased and $IFN-{\gamma}$ increased. In particular, $IL-1{\beta}$ and $IFN-{\gamma}$ showed a similar rate of increase and decrease comparing positive control in DCL 400 mg/kg. $TGF-{\beta}$1 was increased in all DCL groups, filaggrin and VEGF were increased in only DCL 400 mg/kg groups. EGF did not make any changes. Epidermis, dermis thickness and eosinophil infiltration were also decreased in all DCL groups. Conclusions : By increasing Th1 cytokine and decreasing Th2 cytokine, DCL extracts appear to be effective in controlling immune response imbalances, anti-inflammatory and skin regeneration and are likely to be available as a treatment for AD.