• 제목/요약/키워드: Response Rate

검색결과 5,510건 처리시간 0.032초

Efficacy of Bifidobacterium Tetragenous Viable Bacteria Tablets for Cancer Patients with Functional Constipation

  • Liu, Jin;Huang, Xin-En
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제15권23호
    • /
    • pp.10241-10244
    • /
    • 2015
  • Objective: To investigate the efficacy and side effects of Bifidobacterium tetragenous viable bacteria tablets in treating cancer patients with functional constipation during chemotherapy. Methods: A consecutive cohort of 100 cancer patients with functional constipation were divided into two equal groups: patients in the experimental group were given Bifidobacterium tetragenous viable bacteria tablets combined with chemotherapy, while patients in the control group received chemotherapy alone. After 4 weeks, the efficacy and side effects in treating functional constipation were evaluated. Results: Constipation in 48 patients in experimental group was controlled (9 returned to normal), with a total response rate of 96%, and 1 patient reported diarrhea (2%). In contrast only 16 patients in the control group demonstrated improvement and 34 were still constipated after chemotherapy, with a response rate of 32%. The difference in response rate was statistically significant (P<0.05). Conclusion: This study suggested that Bifidobacterium tetragenous viable bacteria tablets are effective and safe in treating cancer patients with functional constipation during chemotherapy.

The Blood Pressure Response during Graded Exercise Test in Obese Adults

  • Shin, Kyung-A
    • 대한의생명과학회지
    • /
    • 제23권3호
    • /
    • pp.215-222
    • /
    • 2017
  • Obesity has been directly associated with the development of hypertension and cardiovascular disease. The purpose of this study was to investigate the blood pressure response during graded exercise test in obese adults. 189 subjects (age: $47.96{\pm}10.23$) were assigned to two groups: non-obese group (N=105, BMI: $22.05{\pm}1.57$, waist circumference: $76.90{\pm}6.17$) and obese group (N=84, BMI: $26.96{\pm}2.51$, waist circumference: $88.29{\pm}6.41$). The subjects underwent health screening and exercise treadmill test from January 2012 to December 2014. Graded exercise test was performed according to the Bruce protocol. Exercise duration (P=0.046) and METs (P=0.015) were significantly lower in obese group than non-obese group. There was no difference in the rate of change in blood pressure response between obese group and non-obese group during exercise, and the recovery rate of systolic blood pressure was delayed in the obese group compared to non-obese group in the first recovery period (P=0.020). The significant factors of increasing rate of change in maximum systolic blood pressure was waist (P=0.046) and hip circumference (P=0.008). In conclusion, these results demonstrate that, for hypertension prevention in obese adults, waist and hip circumference levels should be managed within normal range.

한의사 직종에 대한 한의대생의 인식 연구 - 성별에 따른 차이를 중심으로 (A Study on Korean Medicine College Students' Perception of Korean Medicine Doctors: Focus on Gender Differences)

  • 정하룡;이재혁
    • 동의신경정신과학회지
    • /
    • 제26권3호
    • /
    • pp.211-224
    • /
    • 2015
  • Objectives: This study aimed to investigate gender differences in the Korean Medical Community. Methods: Participants in the research study included 90 students regularly attending the fourth grade in Korean Medicine College, of which 48 were male and 42 were female. Results: 1. Patient's preferences for female KMD (Korean Medicine Doctor) had the lowest response rate in Korean Medical Society. Preferences for male KMD were due to factors including comfort level, rationality, good training, and patient's preference. 2. Patient's preferences for female KMD had the highest response rate in Gynecology, and Pediatrics. On the other hand, patient's preferences for female KMD had the lowest response rate in the other 7 specialty subjects. 3. The reasons for gender discrimination against male KMD were lack of subtlety, lack of empathy, authoritative attitude, and lack of patient management skills. The reasons for gender discrimination, against female KMD were childcare burden, social prejudices, lack of physical strength, and housekeeping burdens. Conclusions: The study results indicated that there was a lower preference for female KMD than male KMD among the Korean Medical Society and in patients' consciousness. Male-centered culture of Korean Medical Society had no role in this finding, but masculine image for KMD jobs and work-family double burden for female KMD were important contributing factors.

Lenalidomide in Treating Patients with Castration-Resistant Prostate Cancer

  • Xing, Dong-Liang;Song, Dong-Kui;Zhang, Li-Rong
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제16권9호
    • /
    • pp.3969-3972
    • /
    • 2015
  • Background: This analysis was conducted to evaluate the efficacy and safety of lenalidomide based regimen in treating patients with castration-resistant prostate cancer. Materials and Methods: Clinical studies evaluating the efficacy and safety of lenalidomide based regimens on response and safety for patients with castration-resistant prostate cancer were identified using a predefined search strategy. A pooled response rate (rate of PSA level decline of ${\geq}50%$) to treatment was calculated. Results: In lenalidomide based regimen, 3 clinical studies which including 98 patients with castration-resistant prostate cancer were considered eligible for inclusion. These lenalidomide based regimens included cisplatin, doxorubicin, or GM-CSF. Pooled analysis suggested that, in all patients, the pooled PSA level decline of ${\geq}50%$ was 13.3% (13/98) in lenalidomide based regimens. Fatigue, nausea and vomitting were the main side effects. No grade III or IV renal or liver toxicity were observed. No treatment related death occurred in patients with lenalidomide based regimens. Conclusions: This evidence based analysis suggests that lenalidomide based regimens are associated with mild response rate and acceptable toxicities for treating patients with castration-resistant prostate cancer.

감초알카로이드에 관한 연구(제 4 보) -감초 알카로이드 분획의 항궤양작용에 대한 검토- (Studies on Alkaloid of Glycyrrhiza glabra L. IV. -Anti-ulcer Activity of Licorice Alkaloid Fraction-)

  • 홍사악;박찬웅;조항영;이철우
    • 대한약리학회지
    • /
    • 제5권2호
    • /
    • pp.149-152
    • /
    • 1969
  • Anti-ulcer activity of licorice alkaloid fraction, separated from Glycyrrhiza glabra L. by fractionation according to general alkaloid purification procedure, were studied with various experimental gastric ulcers. In Shay ulcer, licorice alkaloid fraction inhibit significantly response rate and severity of ulcer. But there was no significant changes in volume and pH of gastric contents. A male rat was fixed on a board and immersed up to breast in water of $25^{\circ}C$ for 20 hrs. Hemorrhage and erosion develop in all the animals on the mucosa of the glandular portion of stomach. Licorice alkaloid fraction (5 mg/kg, 10 mg/kg) inhibit significantly in the severity of stress ulcer but there was no changes in the response rate. Chlorpromazine produce marked inhibition in the severity and response rate of ulcer It was suggested that at least the anti-ulcer activity of licorice alkaloid fraction was not mediated by central depression.

  • PDF

응답표면법에 의한 알루미늄합금의 가공면 거칠기에 관한 연구 (A Study on the Surface Roughness of Aluminum Alloy by Response Surface Nethod)

  • 구자성;김원일;이윤경;왕덕현;박지호
    • 한국산업융합학회 논문집
    • /
    • 제8권1호
    • /
    • pp.31-36
    • /
    • 2005
  • The purpose of this experimental study is to gain equations for the prediction of surface roughness depending on the three major parameters(the cutting speed, the feed rate and the nose radius). It is the merit of Response Surface Methodology that the test time is reduced to minimum size and accurate analysis can be done. On this study, first, made specimen, Al 5052 BE material which is widely used in school and cut the specimen with coated tungsten carbide tools, by varying the cutting conditions, such as the cutting speed, the feed rate and the nose radius. In conclusion, the surface roughness was most greatly influenced by the feed rate. And Surface Roughness equation gained by experiment is as followed $$R=58.2\;v^{-0.22}f^{1.7}r^{-0.66}$$.

  • PDF

Novel Method for Face Recognition using Laplacian of Gaussian Mask with Local Contour Pattern

  • Jeon, Tae-jun;Jang, Kyeong-uk;Lee, Seung-ho
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • 제10권11호
    • /
    • pp.5605-5623
    • /
    • 2016
  • We propose a face recognition method that utilizes the LCP face descriptor. The proposed method applies a LoG mask to extract a face contour response, and employs the LCP algorithm to produce a binary pattern representation that ensures high recognition performance even under the changes in illumination, noise, and aging. The proposed LCP algorithm produces excellent noise reduction and efficiency in removing unnecessary information from the face by extracting a face contour response using the LoG mask, whose behavior is similar to the human eye. Majority of reported algorithms search for face contour response information. On the other hand, our proposed LCP algorithm produces results expressing major facial information by applying the threshold to the search area with only 8 bits. However, the LCP algorithm produces results that express major facial information with only 8-bits by applying a threshold value to the search area. Therefore, compared to previous approaches, the LCP algorithm maintains a consistent accuracy under varying circumstances, and produces a high face recognition rate with a relatively small feature vector. The test results indicate that the LCP algorithm produces a higher facial recognition rate than the rate of human visual's recognition capability, and outperforms the existing methods.

다치 직교 Partial Response Signaling 시스템의 특성에 관한 연구 (The Performance Analysis of Multi-Level Quadrature Partial Response Signaling System)

  • 이광열;고봉진;조성준
    • 한국통신학회논문지
    • /
    • 제13권4호
    • /
    • pp.285-301
    • /
    • 1988
  • 다치 직교 PRS(Partial Response Signaling) 시스템이 잡음, 간섭, 캐리어옵\ulcornerV, 위상지터, 페이딩 등에 의해 개별적으로 또는 복합적으로 영향을 받았을 경우에 대한 PRS 신호의 오율식을 유도하였다. 유도된 식에 의해 반송파 대잡음 전력비, 반송파 대 간섭파 전력비, 위상에러, 임펄스 지수, 가우스성 잡음전력 대 임펄스성 잡음 전력비, PLL(Phase Locked Loop)의 신호 대 잡음전력비, 페이딩 지수 등을 함수로 하여 수치계산을 통해 각 경우의 오율특성을 구했다. 얻은 결과로부터, 일반적으로 임펄스성 잡음보다 오율 특성을 보다 더 열화시키지만 일단 신호가 페이딩을 받게되면 그 반대로 가우스성 잡음이 임펄스성 잡음보다 더욱 에러를 발생시킨다는 것을 알 수 있었다.

  • PDF

동화상내 공기유입속도의 변화에 따른 벼의 광합성반응 (Photosynthetic Response of Rice Plant to Changes of Air Influx Rate into Photosynthetic Chamber)

  • 현동윤;최경구;김진기
    • 한국작물학회지
    • /
    • 제39권6호
    • /
    • pp.526-530
    • /
    • 1994
  • 본 연구는 자연조건에서 생육된 벼를 수정 후 13일에서 15일에 일정한 환경조건으로 옮긴 다음 공기유입속도의 변화(200-280-360-440 ml/min.)에 따른 벼의 광합성 반응을 알아보기 위하여 진행되었다. 공기유입속도의 변화에 따른 경시적인 광합성반응에서, 기공전도율은 처리 후 초기에 급속히 감소한 다음 일정시간동안 동요되다가 약 1시간에서 1시간30분후에 평형상태에 도달되었다. 이와 유사한 변화는 탄소동화율에서도 찾아 볼 수 있었다. 기공전도율은 공기유입속도가 증가함에 따라 감소하였는데, 그 감소율은 탄소동화율에서 나타나는 감소율과 일치되는 경향이었다. 공기의 흐름을 분당 440 ml로 하여 전분이 축적되는 기간동안 처리하였을 경우, 전분덩어리들 간의 결합구조가 느슨하며 전분덩어리를 횡단하였을 경우에는 미세한 구멍이 발생됨을 관찰할 수 있었다. 이상에서 알 수 있는 것은 공기유입속도의 증가에 따른 기공전도율과 탄소동화율은 상호간 관계가 밀접함을 알 수 있으며 공기유입속토의 증가는 광합성과정에서 $CO_2$흡수 및 광합성의 최종산물인 전분구조에 영향을 미칠 수 있음을 시사한다.

  • PDF

발화 속도에 따른 국어의 경계 성조 연구 (Study of Boundary Tone according to Speech Rate in Korean)

  • 박미영
    • 대한음성학회:학술대회논문집
    • /
    • 대한음성학회 2002년도 11월 학술대회지
    • /
    • pp.73-76
    • /
    • 2002
  • The purpose of this paper is to research Korean boundary tone of sentence type and perceptive speaker's attitude according to speech rate - three type. In view of the preceding study, Korean intonation's meaning is determined by boundary tone. Also, in my experimental results, Korean boundary tone of sentence type has preferential tone. However, Korean boundary tone of sentence type is not influential according to speech rate. The speech rate's change of three pattern is influential in auditor's perceptual response. The relationship between the pitch contour of boundary tone and speech rate is not significant.

  • PDF