The Korean Journal of Pharmacology (대한약리학회지)
- Volume 5 Issue 2
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- Pages.149-152
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- 1969
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- 0377-9459(pISSN)
Studies on Alkaloid of Glycyrrhiza glabra L. IV. -Anti-ulcer Activity of Licorice Alkaloid Fraction-
감초알카로이드에 관한 연구(제 4 보) -감초 알카로이드 분획의 항궤양작용에 대한 검토-
- Hong, S.A. (Department of Pharmacology, College of Medicine Seoul National University) ;
- Park, C.W. (Department of Pharmacology, College of Medicine Seoul National University) ;
- Cho, H.Y. (Department of Pharmacology, College of Medicine Seoul National University) ;
- Lee, C.W. (Department of Pharmacology, College of Medicine Seoul National University)
- Published : 1969.12.30
Abstract
Anti-ulcer activity of licorice alkaloid fraction, separated from Glycyrrhiza glabra L. by fractionation according to general alkaloid purification procedure, were studied with various experimental gastric ulcers. In Shay ulcer, licorice alkaloid fraction inhibit significantly response rate and severity of ulcer. But there was no significant changes in volume and pH of gastric contents. A male rat was fixed on a board and immersed up to breast in water of
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