• 콘크리트학회논문집
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• 제15권5호
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• pp.759-767
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• 2003

This paper presents the simplified but more rational analysis method for the prediction of additional internal forces induced in integral abutment bridges. These internal forces depend upon the degree of restraint provided tc the deck by the backfill soil adjacent to the abutments and piles. In addition, effect of the relative flexural stiffness ratio among pile foundations, abutment, and superstructure on the structural behavior is also an important factor. The first part of the paper develops the stiffness matrices, written in terms of the soil stiffness, for the lateral and rotational restraints provided by the backfill soil adjacent to the abutment. The finite difference analysis is conducted and it is confirmed that the results are agreed well with the predictions obtained by the proposed method. The simplified spring model is used in the parametric study on the behavior of simple span and multi-span continuous integral abutment PSC beam bridges in which the abutment height and the flexural rigidity of piles are varied. These results are compared with those obtained by loading Rankine passive earth pressure according to the conventional method. From the results of parametric study, it was shown that the abutment height, the relative flexural rigidity of superstructure and piles, and the earth pressure induced by temperature change greatly affect the overall structural response of the bridge system. It may be possible to obtain more rational and economical designs for integral abutment bridges by the proposed method.

• Structural Engineering and Mechanics
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• 제38권1호
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• pp.39-63
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• 2011

Referring to the formulation of physical stochastic optimal control of structures and the scheme of optimal polynomial control, a nonlinear stochastic optimal control strategy is developed for a class of structural systems with hysteretic behaviors in the present paper. This control strategy provides an amenable approach to the classical stochastic optimal control strategies, bypasses the dilemma involved in It$\hat{o}$-type stochastic differential equations and is applicable to the dynamical systems driven by practical non-stationary and non-white random excitations, such as earthquake ground motions, strong winds and sea waves. The newly developed generalized optimal control policy is integrated in the nonlinear stochastic optimal control scheme so as to logically distribute the controllers and design their parameters associated with control gains. For illustrative purposes, the stochastic optimal controls of two base-excited multi-degree-of-freedom structural systems with hysteretic behavior in Clough bilinear model and Bouc-Wen differential model, respectively, are investigated. Numerical results reveal that a linear control with the 1st-order controller suffices even for the hysteretic structural systems when a control criterion in exceedance probability performance function for designing the weighting matrices is employed. This is practically meaningful due to the nonlinear controllers which may be associated with dynamical instabilities being saved. It is also noted that using the generalized optimal control policy, the maximum control effectiveness with the few number of control devices can be achieved, allowing for a desirable structural performance. It is remarked, meanwhile, that the response process and energy-dissipation behavior of the hysteretic structures are controlled to a certain extent.

• 한국지진공학회논문집
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• 제9권1호통권41호
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• pp.25-32
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• 2005

지진하중을 받는 구조물은 모드참여계수에 의하여 각각의 모드에 지진하중이 분배, 전달된다. 이러한 특성 때문에 모드참여계수는 지진하중을 받는 구조물의 해석에서 매우 중요한 요소이다. 그러나 이상화된 해석 구조물의 모드참여계수는 해석적 모델링이나 시공오차 등에 의하여 실 구조물의 참여계수와 다르기 때문에 실제 거동을 예측, 반영하기에 한계가 있다. 본 연구에서는 시스템 식별기술과 $H^{\infty}$ 최적 모델 응축법을 활용하여, 구조물의 1차 모드참여계수를 산정하는 기법을 제안한다. 이 기법은 시스템 식별로부터 구현된 상태방정식을 전형의 상태방정식과 비교하는 과정에서 시스템의 가제어, 가관측 행렬의 비에 의하여 결정된다. 본 연구에서 제안한 모드참여계수산정기법은 단자유도, 다자유도 전단구조물에 대한 수치해석을 통하여 검증하였다.

• International Journal of Control, Automation, and Systems
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• 제5권2호
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• pp.161-169
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• 2007

The PLL equivalent augmented system incorporated with state feedback is proposed in this paper. The optimal value of filter time constant of loop filter in the phase-locked loop control system and the optimal state feedback gain designed by using linear quadratic regulator approach are derived. This approach allows the PLL control system to employ the large value of the phase-frequency gain $K_d$ and voltage control oscillator gain $K_o$. In designing, the structure of phase-locked loop control system will be rearranged to be a phase-locked loop equivalent augmented system by including the structure of loop filter into the process and by considering the voltage control oscillator as an additional integrator. The designed controller consisting of state feedback gain matrix K and integral gain $k_1$ is an optimal controller. The integral gain $k_1$ related to weighting matrices q and R will be an optimal value for assigning the filter time constant of loop filter. The experimental results in controlling the second-order lag pressure process using two types of loop filters show that the system response is fast without steady-state error, the output disturbance effect rejection is fast and the tracking to step changes is good.

• 대한기계학회논문집
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• 제14권5호
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• pp.1104-1111
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• 1990

본 연구에서는 다자유도계에 국부적으로 존재하는 비선형요소의 위치를 파악 하는 방법에 관하여 연구하였다. 이를 위해 먼저 기존의 등가선형화법으로 구한 등 가행렬에 비선형요소의 위치정보가 포함되어 있음을 밝혔다. 또한 등가행렬에 포함 된 위치정보를 효과적으로 이용하기 위하여 오차행렬법과 오차벡터법을 제시하였다. 제시된 두 방법이 계에 존재하는 국부 비선형요소의 위치파악에 적합한 방법임을 시뮬 레이션을 통하여 검증하였다. 특히 오차벡터법은 비선형요소의 연결상태 및 비선형 성 정도를 파악할 수 있는 방법으로 비선형계의 모델수립에 유용한 도구임을 보였다. 그리고 특수한 경우에는 등가선형화법으로 구한 등가 감쇠 및 등가 강성계수를 응답에 대하여 그래프로 표시하면 그 비선형 형태를 대략적으로 파악할 수 있음을 밝히고 시 뮬레이션으로 검증하였다.

• Biotechnology and Bioprocess Engineering:BBE
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• 제10권2호
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• pp.128-135
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• 2005

Mixed-mode hydrophobic/ionic matrices exhibit a salt-tolerant property for adsorbing target protein from high-ionic strength feedstock, which allows the application of undiluted feedstock via an expanded bed process. In the present work, a new type of mixed-mode adsorbent designed for expanded bed adsorption, Fastline $PRO^{\circledR}$, was challenged for the capture of nattokinase from the high ionic fermentation broth of Bacillus subtilis. Two important factors, pH and ion concentration, were investigated with regard to the performance of nattokinase ad-sorption. Under initial fermentation broth conditions (pH 6.6 and conductivity of 10 mS/cm) the adsorption capacity of nattokinase with Fastline PRO was high, with a maximum capacity of 5,350 U/mL adsorbent. The elution behaviors were investigated using packed bed adsorption experiments, which demonstrated that the effective desorption of nattokinase could be achieved by effecting a pH of 9.5. The biomass pulse response experiments were carried out in order to evaluate the biomass/adsorbent interactions between Bacillus subtilis cells and Fastline PRO, and to demonstrate a stable expanded bed in the feedstock containing Bacillus subtilis cells. Finally, an EBA process, utilizing mixed-mode Fastline PRO adsorbent, was optimized to capture nattokinase directly from the fermentation broth. The purification factor reached 12.3, thereby demonstrating the advantages of the mixed-mode EBA in enzyme separation.

• Archives of Plastic Surgery
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• 제46권1호
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• pp.34-38
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• 2019

Background Acellular dermal matrices (ADMs) have recently become widely used in breast reconstruction, but the correlation between the final expander volume and the surface area of the ADM is not well understood. In this study, the expansion of the surface area of ADM and the expander volume was studied retrospectively in cases of acellular dermis-assisted tissue expander breast reconstruction. Methods Twenty cases of immediate breast reconstruction using an ADM-assisted tissue expander from January 2015 to December 2015 were evaluated. In all 20 cases, CGCryoDerm was used as the matrix, with a thickness of 1-3 mm. No slit incisions were made. Finally, the proportional increase in the area of the fully expanded ADM was compared to that of the tissue expander volume. Results The proportional increase in the ADM surface area was calculated to be from 1.1 to 2.46, with a mean value of 1.7. Additionally, under the assumption that the expander had a spherical shape, the increase in its radius (the cube root of its volume) was assessed. The range of the proportional increase in the expander radius was 1.1 to 2.24, with a mean value of 1.66. The proportional increase in the radius of the expanded ADM surface area ranged from 1.04 to 1.34, with a mean ratio of 1.28. Conclusions The results of this study confirmed that the ADM expanded when the tissue expander was inflated. However, the ADM expanded to a lesser extent than the tissue expander, indicating that the muscle and other tissues expanded more than the ADM when the tissue expander was inflated.

• International Journal of Oral Biology
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• 제45권4호
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• pp.190-196
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• 2020

Several factors, including genetic and environmental insults, impede protein folding and secretion in the endoplasmic reticulum (ER). Accumulation of unfolded or mis-folded protein in the ER manifests as ER stress. To cope with this morbid condition of the ER, recent data has suggested that the intracellular event of an unfolded protein response plays a critical role in managing the secretory load and maintaining proteostasis in the ER. Tauroursodeoxycholic acid (TUDCA) is a chemical chaperone and hydrophilic bile acid that is known to inhibit apoptosis by attenuating ER stress. Numerous studies have revealed that TUDCA affects hepatic diseases, obesity, and inflammatory illnesses. Recently, molecular regulation of ER stress in tooth development, especially during the secretory stage, has been studied. Therefore, in this study, we examined the developmental role of ER stress regulation in tooth morphogenesis using in vitro organ cultivation methods with a chemical chaperone treatment, TUDCA. Altered cellular events including proliferation, apoptosis, and dentinogenesis were examined using immunostaining and terminal deoxynucleotidyl transferase dUTP nick end labeling assay. In addition, altered localization patterns of the formation of hard tissue matrices related to molecules, including amelogenin and nestin, were examined to assess their morphological changes. Based on our findings, modulating the role of the chemical chaperone TUDCA in tooth morphogenesis, especially through the modulation of cellular proliferation and apoptosis, could be applied as a supporting data for tooth regeneration for future studies.

• Composites Research
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• 제36권5호
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• pp.369-376
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• 2023

본 연구에서는 복합소재의 기지재로 활용되고 있는 에폭시 고분자의 가교율이 항복표면에 미치는 영향을 분자동역학 해석을 통해 평가하고자 한다. 분자동역학 해석을 활용하여 가교율에 따른 에폭시 모델을 형성한 후, 상온-대기압 조건하에서 단축 변형 해석 및 평면응력 조건을 고려한 다축 변형 해석을 수행하였으며, 해석 데이터를 통하여 가교율에 따른 영률, 항복점, 항복표면, 그리고 경화지수를 도출하였다. 해석 결과, 영률 및 응력은 기존 선행 연구들에서 조사되었듯이, 가교율에 따라 증가하는 경향을 확인하였다. 다축 변형 시에는, 이러한 가교율과 도출된 응력간의 관계가 하중의 방향에 따라 의존적임을 확인하였는데, 가교율이 증가할수록 단축 인장 영역에 비해, 이축 압축 영역의 항복표면은 빠른 속도 팽창하였으며, 이로 인한 항복표면의 상이함을 관측하였다. 이를 통해, 고분자 소재의 항복 표면의 압력의존성은 소재의 가교 정도에 의존적이며, 항복이 진행될수록, 압력의 존성은 동일 소재 하에서도 변할 수 있음을 확인하였다.

• 전자공학회논문지
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• 제54권2호
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• pp.123-129
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• 2017

본 논문에서는 이중 마이크로폰 배열을 이용하여 비음수 행렬분해(nonnegative matrix factorization, NMF) 기반으로 다중음원의 도래각을 추정하는 새로운 방법을 제안한다. 우선 이중 마이크로폰 배열에 들어온 음향 신호들을 연속된 분석프레임으로 분할한 후, 각 프레임에 대해 조향응답파워 위상변환(steered-response power phase transform, SRP-PHAT) 빔형성기를 적용하여 스테레오 신호들을 시간-방향 영역으로 표현한다. 이러한 SRP-PHAT의 시간-방향 출력값들은 사전에 정의된 프레임 수만큼 누적하여 시간-방향 블록으로 정의한다. 다음으로, 잡음에 강건한 도래각 추정을 위하여, 각 시간-방향 블록을 블록차감 기법을 사용하여 매 프레임에 대해 정규화한다. 이후, 다중음원 환경에서 각 음원의 방향을 클러스터링하기 위해 정규화된 시간-방향 블록에 비지도(unsupervised) NMF를 적용한다. 구체적으로, 음원의 개수와 이들의 도래각을 추정하는데 각각 활성 및 기저 행렬들을 사용한다. 제안된 방법의 도래각 추정 성능을 평가하기 위해 이중 마이크로폰 배열로부터 입력된 [$-35{\circ}$, 5m], [$12{\circ}$, 4m], 그리고 [$38{\circ}$, 4.m]에 각각 위치한 세 가지 음원들에 대한 추정 오차의 절대 평균(mean absolute error, MAE) 및 오차의 표준편차를 측정하였다. 실험 결과. 제안된 방법은 기존의 SRP-PHAT 기반 도래각 추정방법에 비해 상대적으로 MAE를 56.83% 줄일 수 있었다.