• 한국지진공학회:학술대회논문집
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• 한국지진공학회 2003년도 춘계 학술발표회논문집
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• pp.422-429
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• 2003

A comparative study was performed for a suspension bridge to grasp the possible differences in seismic responses evaluated by several analytical methods. The items mainly investigated are the linear vs. nonlinear response the response spectrum method vs. the linear dynamic analysis method and the damping ratio and it's implementation into analysis procedures. According to the numerical example, it is found that the seismic responses are considerably affected by the damping-related parameters even though slight differences are shown depending on the response quantities md the exciting directions. On the other hand, it is also confirmed that the seismic responses are less affected by the analysis method-related parameters such as the response spectrum method vs. the linear dynamic analysis method, and the linear and nonlinear analysis method. The response spectrum method is expected to give conservative results for the examined bridge, provided that the design response spectrum in the Korean Highway Design Specification is modified according to the proper damping ratio.

• 한국지진공학회:학술대회논문집
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• 한국지진공학회 2003년도 춘계 학술발표회논문집
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• pp.110-117
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• 2003

The result of recent seismic hazard analysis indicates that the ground motion response spectra for Korean nuclear power plant site have relatively large high frequency acceleration contents. In the ordinary seismic fragility analysis of nuclear power plant structures and equipments, the safety margin of design ground response spectrum is directly used as a response spectrum shape factor. The effects of input response spectrum shape on the floor response spectrum were investigated by performing the direct generation of floor response spectrum from the ground response spectrum. The safety margin included in the design ground response spectrum should be considered as a floor response spectrum shape factor for the seismic fragility analysis of the equipments located in a building.

• 대한미생물학회지
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• 제16권1호
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• pp.57-64
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• 1981

The clinical need for agents to modify immune response in the treatment of viral infection has lead to an increased interest in cellular and biochemical mechanisms regulating the immune response and to the development of a variety of biological and chemical substance with immunomodulatory activity. Inosiplex has shown antiviral activity in tissue culture, animal models and huamn studies through augmentation of immune response. However, the effect of inosiplex on immune response in animal has not been extensively analyzed, and the effect of inosiplex on immune response has been paradoxical depending on the time of administration of inosiplex in relation to that of antigen. Therefore, this study was undertaken to assess the effect of inosiplex on the immune response to sheep red blood cells(SRBC) in normal and viral infected mice. Inosiplex increased cellular immune response and plaque forming lymphocyte response to SRBC, decreased the recovery of S. typhimurium from infected mice spleen, and restored the depressed cellular immune response by measle and newcastle disease virus infections. All of the above results were observed only when inosiplex was given after immunization but did not when given before immunization. These results indicate that inosiplex stimulate the efferent are of immune response and may even block the afferent are, and suggest that inosiplex is a very promising drug in therapy of many viral infections.

• 한국해양환경ㆍ에너지학회지
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• 제3권1호
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• pp.3-24
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• 2000

한국연안도 해상교통량 증가, 선원자질저하 및 노후선박증가로 수만톤을 초과하는 기름유출사고의 위험이 상존하고 있다. 이러한 대형 오염사고 발생에 효과적으로 대응하기 위한 선진 방제체제의 구축방안은 다음과 같다. 1. 범국가적 차원의 국가긴급계획을 효율적으로 실행하기 위한 과학적인 지역긴급계획의 수립 2. 2만톤의 축가방제능력 조기 확보 3. 해양오염방제 전문교육ㆍ훈련의 강화 4. NOWPAP사업 추진등 인접국가간 방제협력체제의 구축 21세기 방제정책은 선진 방제체제를 조기에 구축하여 방제작업의 과학적ㆍ전문화ㆍ국제화를 동한 실행적 방제능력 향상에 주력하여야 할 것이다.

• 한국지진공학회논문집
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• 제7권4호
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• pp.23-30
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• 2003

최근 수행된 우리나라 원전 부지에 대한 지진재해도 해석 결과 작성된 등재해도 스펙트럼에서 고진동수 성분의 지진동이 매우 우세하게 나타나고 있다. 일반적으로 지진취약도 해석에서는 설계 스펙트럼에 내재된 보수성을 평가하기 위해 스펙트럼 형상계수가 사용된다. 본 연구에서는 입력지반운동 스펙트럼의 형상이 변화함에 따른 층응답스펙트럼의 형상 변화를 분석하였다. 이때 입력 스펙트럼으로부터 직접 층응답스펙트럼을 작성할 수 있는 직접법을 사용하였다. 본 연구 결과 건물 내부에 설치된 기기의 취약도해석에서는 입력스펙트럼에 내재된 보수성을 구조물의 고유진동수에 대한 스펙트럼 형상계수가 아닌 기기의 고유진동수에 따른 층응답스펙트럼 형상계수로 고려하는 것이 정확한 취약도해석 결과를 주는 것으로 나타났다.

• 응용통계연구
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• 제26권3호
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• pp.375-387
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• 2013

통계조사에서 단위 무응답은 표본크기를 축소시켜 추정값의 효율을 떨어뜨릴 뿐만 아니라, 주요 관심변수에 대해 응답자와 무응답자간의 차이가 존재하는 경우 무응답 편향(bias)을 발생시키는 요인으로 일반적으로 가중값 조정방법을 이용하여 보정한다. 대부분의 조사에서 무응답 표본에 대한 정보를 얻는 것은 현실적으로 매우 어려우며, 무응답으로 인한 추정값의 편향 정도를 파악하는 것 또한 쉽지 않다. 통계청에서는 2010년, 2011년 가구패널조사인 가계 금융조사를 실시하였다. 2010년 1차 웨이브는 1만 가구에 대해 모두 응답한 정보를 가지고 있으며, 2011년 2차 웨이브에는 부재, 거부 등으로 인한 무응답 표본(약 10%)이 존재한다. 본 연구에서는 2차 웨이브의 무응답 표본들을 무응답 성향이 강한 표본으로 가정하고 1차 웨이브에서 무응답가구로 분류한 후 무응답 가구의 특성과 무응답 편향정도 및 무응답 조정 효과를 분석하였다.

• 대한인간공학회지
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• 제32권3호
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• pp.217-227
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• 2013

Objective: The purpose of this study was to analyze 'response time', 'peak response time' and 'overshoot value' for each muscle by applying the EMG signal to the vehicle response in ISO 7401 and to quantify the response of the driver according to vehicle characteristics by comparing vehicle characteristics and muscle responses of the driver. Background: The Open-loop test defined in international standards ISO 7401 is the only method for evaluating the performance of the vehicle. However, this test was focused only on mechanical responses, not driver's ones. Method: One skilled male driver(22 yrs. experience) was participated in this experiment to measure muscle activities of the driver in transient state. Then the seven muscle signals were applied to calculate 'response time', 'peak response time', and 'overshoot value'. Results: In the analyses of the EMG data, the effects of vehicle type and muscle were statistically significant on the 'response time' and 'peak response time'. Also, the effects of vehicle type, muscle, and lateral acceleration level were statistically significant on the 'overshoot value' in this study. According to the analyses of the vehicle motion data, vehicle motion variable(LatAcc, Roll, YawVel) was statistically significant on the 'response time' and vehicle type, vehicle motion variable, and lateral acceleration level were statistically significant on the 'peak response time', respectively. Conclusion: In the analyses of the 'response time' and 'overshoot value', the data of muscle activities(EMGs) was better index that could evaluate the vehicle characteristic and performance than the data of vehicle motion. In case of peak response time, both EMG and vehicle motion data were good index. Application: The EMGs data from a driver might be applicable as index for evaluation of various vehicle performances based on this study.

• Earthquakes and Structures
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• 제3권3_4호
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• pp.341-363
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• 2012

The spectral representation method is a quick and versatile tool for the generation of spatially variable, response-spectrum-compatible simulations to be used in the nonlinear seismic response evaluation of extended structures, such as bridges. However, just as recorded data, these simulated accelerations require processing, but, unlike recorded data, the reasons for their processing are purely numerical. Hence, the criteria for the processing of acceleration simulations need to be tied to the effect of processing on the structural response. This paper presents a framework for processing acceleration simulations that is based on seismological approaches for processing recorded data, but establishes the corner frequency of the high-pass filter by minimizing the effect of processing on the response of the structural system, for the response evaluation of which the ground motions were generated. The proposed two-step criterion selects the filter corner frequency by considering both the dynamic and the pseudo-static response of the systems. First, it ensures that the linear/nonlinear dynamic structural response induced by the processed simulations captures the characteristics of the system's dynamic response caused by the unprocessed simulations, the frequency content of which is fully compatible with the target response spectrum. Second, it examines the adequacy of the selected estimate for the filter corner frequency by evaluating the pseudo-static response of the system subjected to spatially variable excitations. It is noted that the first step of this two-fold criterion suffices for the establishment of the corner frequency for the processing of acceleration time series generated at a single ground-surface location to be used in the seismic response evaluation of, e.g. a building structure. Furthermore, the concept also applies for the processing of acceleration time series generated by means of any approach that does not provide physical considerations for the selection of the corner frequency of the high-pass filter.

• 인터넷정보학회논문지
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• 제22권3호
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• pp.53-58
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• 2021

보안관제 분야의 실제 업무활동에 대해서는 거의 연구가 없는 실정이다. 이에 본 논문에서는 보안관제의 위협정보 탐지 대응시간 모델링을 통해 적정 투입인력 규모 산정에 기여하고 최신 보안솔루션 투입시의 효과성 분석 등에 활용할 수 있는 실질적인 연구 방법론을 제시하고자 한다. 보안관제센터에서 수행하는 전체 위협정보 탐지대응시간은 TIDRT(Total Intelligence Detection & Response Time)로 정의한다. 전체 위협정보 탐지 대응시간(TIDRT)는 내부 위협정보 탐지대응시간(IIDRT, Internal Intelligence Detection & Response Time)과 외부 위협정보(EIDRT, External Intelligence Detection & Response Time)의 합으로 구성된다. 내부위협정보 탐지대응시간(IIDRT)는 다섯 단계의 소요시간의 합으로 계산할 수 있다. 본 연구의 궁극적인 목표는 보안관제센터의 주요한 업무활동들을 수식으로 모델링하여 보안관제센터의 사이버 위협정보 탐지대응시간 계산식을 산정하는데 있다. 2장에서는 선행연구를 살펴보고, 3장에서는 전체 위협정보 탐지대응시간의 계산식을 모델링한다. 4장에서 결론으로 끝을 맺는다.

• 대한미생물학회지
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• 제6권1호
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• pp.29-40
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• 1971

Various kinds of antibiotics are generally believed to have inhibitory effects on the antibody response. However, as polymyxin B which belongs to the cyclic polypeptide group of antibiotic was found to have some enhancing effects on the antibody response of rabbits to enterobacterial common antigen(CA) under specified conditions, experiments were carried out on this problem with the following results. 1. When mixture of polymyxin B and CA derived from Salmonella typhimurium(STM) was treated 30 minutes at $37^{\circ}C$ and injected three times into rabbits by intravenous route, the antibody response to CA was weaker than rabbits injected CA only. 2. Mixture of polymyxin B and CA showed a marked antibody production when injected into rabbits primed with small amounts of heat-extracted antigen of STM, while the injection of CA alone showed low titers of response. 3. Mixture of polymyxin B and heat-extracted CA-containing antigen of Escherichia coli 014 also showed a increased antibody production than CA alone in rabbits primed with antigen of STM. 4. The effect of polymyxin B appeared in different ways. This antibiotic did not enhance the CA antibody response in rabbits primed with small amounts of E. coli 0111 and 055, but enhance in rabbits primed with Shigella flexneri. 5. No enhancing effect on the antibody response was observed by polymyxin B in rabbits primed with CA. 6. No enhancing effect on the antibody response was also noted in rabbits primed with STM antigen in case polymyxin B and CA were administered simultaneously but in veins of different places. 7. Bacitracin did not enhance the CA antibody response in primed rabbits with STM antigen, but neomycin slightly enhance the response. 8. Lipopolysaccharide showed no priming effect on the CA antibody response, and no enhancement of the CA antibody response in rabbits printed with STM. 9. The priming effect of STM antigen against CA antibody response was very weak as compared with the effect of CA derived from STM antigen.