• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.34 no.3B
• /
• pp.311-317
• /
• 2009

The traditional network anomaly detection systems execute the threshold-based detection without considering dynamic network environments, which causes false positive and limits an effective resource utilization. To overcome the drawbacks, we present the adaptive network anomaly detection model based on artificial immune system (AIS) in centralized network. AIS is inspired from human immune system that has learning, adaptation and memory. In our proposed model, the interaction between dendritic cell and T-cell of human immune system is adopted. We design the main components, such as central node and router node, and define functions of them. The central node analyzes the anomaly information received from the related router nodes, decides response policy and sends the policy to corresponding nodes. The router node consists of detector module and responder module. The detector module perceives the anomaly depending on learning data and the responder module settles the anomaly according to the policy received from central node. Finally we evaluate the possibility of the proposed detection model through simulation.

• The Korean Journal of Pain
• /
• v.34 no.4
• /
• pp.479-486
• /
• 2021

Background: Prior studies have reported that 40%-90% of the patients with celiac plexus-mediated visceral pain benefit from the neurolytic celiac plexus block (NCPB), but the predictive factors of response to NCPB have not been evaluated extensively. This study aimed to identify the factors associated with the immediate analgesic effectiveness of NCPB in patients with intractable upper abdominal cancer-related pain. Methods: A retrospective review was performed of 513 patients who underwent NCPB for upper abdominal cancer-related pain. Response to the procedure was defined as (1) a decrease of ≥ 50% or ≥ 4 points on the numerical rating scale (NRS) in pain intensity from the baseline without an increase in opioid requirement, or (2) a decrease of ≥ 30% or ≥ 2 points on the NRS from the baseline with simultaneously reduced opioid consumption after NCPB. Logistic regression analysis was performed to determine the factors associated with successful responses to NCPB. Results: Among the 513 patients included in the analysis, 255 (49.8%) and 258 (50.2%) patients were in the non-responder and responder group after NCPB, respectively. Multivariable logistic regression analysis showed that diabetes (odds ratio [OR] = 0.644, P = 0.035), history of upper abdominal surgery (OR = 0.691, P = 0.040), and celiac metastasis (OR = 1.496, P = 0.039) were the independent factors associated with response to NCPB. Conclusions: Celiac plexus metastases, absence of diabetes, and absence of prior upper abdominal surgery may be independently associated with better response to NCPB for upper abdominal cancer-related pain.

• The Magazine of the IEIE
• /
• v.19 no.10
• /
• pp.126-134
• /
• 1992

비행기 속, 열차의 속 어디에서나 사무실이나 가정과 연락을 취할 수 있는 다중체통신, 위성통신은 현재, 전화, TV의 전송, 전용선 등에 폭넓게 이용되고 있다. 최근까지 정지위성 궤도상에 떠있는 트란스폰도(transponder=transmitter+responder<송신기+응답기>) 즉, 위성 탑재 중단기의 수는 INTELSAT를 포함해서 합계 약 4,100으로 되어 있다(과거의 공산권을 포함해서). 발사로켓의 대형화, 통신위성의 대형화에 의해 위성회선의 비용은 현저히 저하되어 있으며, 위성통신의 이용은 확대일로에 있다. 위성통신은 광화이버통신, 지상마이크로파통신과 나란하는 통신네트워크의 주요한 구성요소이다. 대양횡단의 통신은 위성통신이 그 특징을 충분히 발휘하여 왔고, 해저광케이블과의 사이에서 부설자끼리 장단점을 놓고 비교를 하고 있으나, 위성통신은 넓은 지역으로부터의 통신을 수 하는 기능 또는 동일한 신호를 넓은 지역에 탑재하는 지구국에서 동시에 수신할 수 있는 기능을 갖고 있는 이외에도, 원양어선에로의 통신같이, 지상의 통신방식으로는 제공이 곤란한 서비스가 가능하다는 등의 특징이 있으며, 금후의 통신 네트워크의 구성요소로서 더 한층 그 필요성이 증가해 갈 것이라 본다.

• Proceedings of the Korean Society of Applied Pharmacology
• /
• 2001.11a
• /
• pp.35-36
• /
• 2001

According to the recent epidemiological data, the numbers of patients of Reumatoid Arthritis(RA) in the world are reported to be 350mi11ion and 700,000 in the world and in Japan, respectively For the treatment of RA, NASIDs as the first choice drug have been widely used worldwide, and more than 50 NSAIDs have been in market up to today in Japan. Early 1990s, DMARDs as the new drug for RA treatment came into market, and the number of DMARDs has been increased every year. These drugs are recognized to have several advantages in treatment of RA, however, disadvantages are also reported, i.e., (1) high incidence of side effects, (2) high non-responder population, (3) decreased efficacy in chronic treatment, and (4) slow starting of the efficacy. For example, Methotrexate which has been widely used as the immunosuppressant has been recently used for treatment of Reumatoid. However, this drug has several disadvantages such as 60-70% improvement of the disease, 80% incidence of side effects, and 2-4 weeks to recognize the efficacy after treatment. In addition to these two.

• 대한생식의학회:학술대회논문집
• /
• 2006.11a
• /
• pp.151-152
• /
• 2006

• Journal of the Korea Society for Simulation
• /
• v.13 no.4
• /
• pp.43-53
• /
• 2004

The distributed OCSP (Online Certificate Status Protocol), composed of multiple responders, is a model that enhances the utilization of each responder and reduces the response time. In a multi-user distributed environment, load balancing mechanism must be developed for the improvement of the performance of the whole system. Conservative load balancing algorithms often ignore the communication cost of gathering the information of responders. As the number of request is increased, however, fail to consider the communication cost may cause serious problems since the communication time is too large to disregard. We propose an adaptive load balancing algorithm and evaluate the effectiveness by performing modeling and simulation. The principal advantage of new algorithm is in their simplicity: there is no need to maintain and process system state information. We evaluated the quality of load balancing achieved by the new algorithm by comparing the queue size of responders and analyzing the utilization of these responders. The simulation results show how efficiently load balancing is done with the new algorithm.

• Journal of the Korean Institute of Telematics and Electronics B
• /
• v.33B no.9
• /
• pp.70-79
• /
• 1996

Block data transfer poses a serious problem is a pipelined bus where each data transfer step is pipelined. In this paper, we describe the design and implementation of a variable data block transfer protocol for a pipelined bus of a shared-memory multiprocessor. The proposed method maintains compatibility with the existing protocol for the pipelined bus and ensures fairness and effectiveness by preventing starvation. We present flow charts of requester and responder during a block transfer in the pipelined bus that uses the proposed protocol. The proposed protocol was implemented for the TICOM-III HiPi+Bus.

• The Korean Journal of Emergency Medical Services
• /
• v.13 no.3
• /
• pp.5-17
• /
• 2009

Purpose : This study was to examine the knowledge and attitude about cardiopulmonary resuscitation(CPR) for nursing students, and to basic data with CPR education program for nursing student. Method : 128 nursing students filled out a self-administered questionnaires. The data were collected by CPR knowledge and attitude modified by the authors based on Kim's inventory (2008). Result : Nursing students weren't knowledgeable nor confident of CPR. But they had positive attitude about as a first responder. Conclusion : Intensive education by the level of knowledge should be provided for nursing students to master the knowhow of CPR, especially cardiac compression, and evaluation should be reinforced as well. And an education should be offered to enhance their confidence CPR performing CPR.

• Clinical and Experimental Pediatrics
• /
• v.48 no.4
• /
• pp.416-424
• /
• 2005

Purpose : To find the risk factors associated with coronory artery lesions, non-responsiveness to intravenous immunoglobulin(IVIG) treatment, and recurrences in Kawasaki disease patients. Methods : We retrospectively analyzed 1,000 Kawasaki disease patients who were admitted to Yonsei University Medical Center from September 1990 to December 2003. We compared between responder and non-responder groups to IVIG treatment as well as between relapsed and non-relapsed groups, and as to the relapsed group, we also compared variables between patients in their first and second attack states. Finally, factors associated with longer-fever duration from disease onset were evaluated. Results : Longer fever durations before and after IVIG treatment, male sex, lower Hgb and Hct level, higher WBC count and segmented WBC proportion, and higher CRP and Harada's score were related with coronary artery lesions. Non-responsiveness was related to higher WBC count, segmented WBC proportion, CRP, SGPT, Harada's score, and pyuria. Moderate-to-severe coronary artery dilatations and recurrences were more commonly seen among the non-responder group. No significant predictive factors for recurrence were found. In the relapsed group, lower WBC count, CRP, and shorter fever duration from disease onset were observed in their second attack state. Fever duration from disease onset showed positive correlation with WBC count, CRP, and Harada's score and negative correlation with Hgb levels. Conclusion : Higher WBC count, CRP, and higher Harada's score were related to both higher incidences of coronary artery lesions and non-responsiveness to IVIG treatment, and these factors were also related with longer fever duration. Non-responders to IVIG treatment showed higher recurrence rate and more moderate-to-severe coronary artery dilatations than responders.

• Clinical and Experimental Reproductive Medicine
• /
• v.34 no.2
• /
• pp.125-131
• /
• 2007

Objective: The aim of this study was to compare GnRH antagonist and agonist flare-up treatment in the management of poor responder patients. Methods: One hundred forty-four patients from Jan. 1, 2002 to Aug. 31, 2005 undergoing IVF/ICSI treatment who responded poorly to the previous cycle (No. of oocyte retrieved$\leq$5) and had high early follicular phase follicle stimulating hormone (FSH>12 mIU/ml were selected. Seventy-five patients received agonist flare-up protocol and 71 patients received antagonist protocol. We analyzed the number of oocytes retrieved, number of good embryos (GI, GI-1), total dose of hMG administered, implantation rate, cycle cancellation rate, pregnancy rate, live birth rate. Results: The cancellation rate was high in antagonist protocol (53.5% vs. 30.1%). The number of oocyte retrieved, the number of good embyos were high in agonist flare-up group. There was no statistical difference between GnRH agonist flare up protocol and GnRH antagonist protocol in implantation rate (14.5%, 10.1%), clinical pregnancy rate per transfer (29.4%, 21.2%) and live birth rate per transfer (21.6%, 18.2%). Although the result was not statistically significant, GnRH agonist flare up group showed a nearly doubled pregnancy rate and live birth rate per initial cycle than GnRH antagonist group. Conclusions: The agonist flare-up protocol appears to be slightly more effective than the GnRH antagonist protocol in implantation rate, pregnancy rate, live birth rate but shows statistically no significance. Agonist flare-up protocol improved the ovarian response in poor responders. However, based of the result of the study, we can expect improved ovarian response in poor responders by GnRH agonist flare up protocol.