• Journal of Microbiology
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• 제43권4호
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• pp.366-369
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• 2005

Avian influenza viruses playa crucial role i,n the creation of human pandemic viruses. In this study, we have demonstrated that both human and avian influenza receptors exist in cells in the respiratory and intestinal tracts of chickens. We have also determined that primarily cultured chicken lung cells can support the replication of both avian and human influenza viruses.

• IMMUNE NETWORK
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• 제20권6호
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• pp.44.1-44.19
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• 2020

The human body is continuously threatened by pathogens, and the immune system must maintain a balance between fighting infection and becoming over-activated. Mucosal surfaces cover several anatomically diverse organs throughout the body, such as the respiratory and gastrointestinal tracts, and are directly exposed to the external environment. Various pathogens invade the body through mucosal surfaces, making the mucosa the frontline of immune defense. The immune systems of various mucosal tissues display distinctive features that reflect the tissues' anatomical and functional characteristics. This review discusses the cellular components that constitute the respiratory and gastrointestinal tracts; in particular, it highlights the complex interactions between epithelial and immune cells to induce Ag-specific immune responses in the lung and gut. This information on mucosal immunity may facilitate understanding of the defense mechanisms against infectious agents that invade mucosal surfaces, such as severe acute respiratory syndrome coronavirus 2, and provide insight into effective vaccine development.

• 한국화재소방학회논문지
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• 제21권2호
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• pp.64-73
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• 2007

호흡기 내에서 유해물질의 체내흡수 및 방어특성은 영역별로 다르며 흡입연기의 장 단기 인체 유해성은 연기의 호흡기 내 침착위치 및 침착밀도와 밀접한 관계를 가지고 있다. 이 연구에서는 미소부피 위치 추적법을 이용한 입자침착율 계산 기법을 사용하여 휴식 및 가벼운 운동에 해당하는 호흡조건별로 또한 구강 및 비강 호흡별로 각 입자크기에 대하여 호흡기 각 영역별로 단위 면적당 침착분율 등 침착 특성을 구하였다. 이 결과는 연기에 흡착된 유해물질의 체내 흡수량 산정 등에 이용되어 연기의 인체 유해성 판정에 도움을 줄 수 있을 것으로 판단된다.

• Tuberculosis and Respiratory Diseases
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• 제72권6호
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• pp.507-510
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• 2012

Carbohydrate antigen 19-9 (CA19-9) is a specific tumor marker of the biliary, pancreatic and gastrointestinal tracts. CA19-9 is occasionally elevated in serum in patiens with benign pulmonary diseases such as bronchiectasis, idiopathic interstitial pneumonia or collagen disease-associated pulmonary fibrosis. Intralobar pulmonary sequestration is an uncommon congenital lung anomaly. It is dissociated from the normal tracheobronchial tree and is supplied by an anomalous systemic artery. There have been some reports of elevation of CA19-9 in this lesion. We report a case of intralobar pulmonary sequestration with elevated serum CA19-9 in a 29-year-old man who was diagnosed with bronchiectasia of left lower lung field on general check up. He had no evidence of any malignant disease in pancreatobiliary or gastrointestinal tracts. Elevated serum CA19-9 level might be encountered with benign pulmonary disease such as pulmonary sequestration.

• 대한치과마취과학회지
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• 제6권2호
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• pp.121-126
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• 2006

Generalized anaphylaxis is a most dramatic and acutely life-threatening allergic reaction. Most fatalities from anaphylaxis occur within the first 30 minutes postantigenic exposure. The mechanism of generalized anaphylaxis is the reaction of IgE antibodies to an allergen that causes the release of histamine, bradykinin, and others. These chemical mediators cause the contraction of smooth muscles of the respiratory and intestinal tracts, as well as increased vascular permeability. Four major clinical symptoms are recognized: skin reactions, smooth muscle spasm (gastrointestinal and genitourinary tracts and respiratory smooth muscle), respiratory distress, and cardiovascular collapse. Epinephrine is the drug of choice for the management. Its syrnpathomimetic effects directly counteract most aspects of the attack. Respiration must be immediately supported by the establishment of a patent airway along with artificial ventilation. The circulation should be supported and the existing hypotension overcome by placing the victim in a position to allow gravity to aid venous return and by administering intravenous fluids, vasopressors, and corticosteroids. When an imperceptible pulse is evident, external cardiac compression must also be instituted. This is a case report of anaphylactic shock care during general anesthesia, possibly due to penicillin, pancuronium and others.

• Tuberculosis and Respiratory Diseases
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• 제67권5호
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• pp.409-412
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• 2009

Background: Several large outbreaks have demonstrated the threat of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in close-contact environments, such as occurs during training and quartering of military recruits training. In South Korea, which is a hospital or healthcare-associated MRSA prevalent area, military service is compulsory for all healthy young men. We surveyed and determined the extent of CA-MRSA colonization in the upper respiratory tracts of Korean military recruits. Methods: The Korean military recruits who were enrolled in a military training facility from November 2004 to March 2005 were eligible for this study. Sputum or nasopharyngeal swap was obtained from randomly selected subjects who displayed upper respiratory tract symptoms. Results: Of the 181 participants, 32 participants (17.7%) were colonized with S. aureus, and 12 participants (6.6%) were colonized with MRSA. Among the cases that were colonized with S. aureus, 37.5% (12/32) were colonized with MRSA. Antimicrobial susceptibility testing showed resistant patterns that were suggestive of the CA-MRSA strains for all of the MRSA isolates. Conclusion: This study of Korean military recruits found a great deal of showed MRSA colonization in them, and the antimicrobial resistant profile that was suggestive of a CA-MRSA strain. Further efforts to prevent the spread of MRSA infections and careful monitoring for CA-MRSA outbreaks are warranted, especially in a high risk group such as military recruits.

• Tuberculosis and Respiratory Diseases
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• 제54권3호
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• pp.346-352
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• 2003

저자들은 호흡곤란, 객담, 기침을 주소로 내원한 23세 남자환자에서 기관지 내시경 및 VATS로 시행한 조직검사상 후두와 함께 기관, 기관지 및 폐실질을 침범한 유두종증으로 진단받고 interferon-${\alpha}$ 치료 후 호전을 보인 재발성 호흡기계 유두종증 1예를 경험하였기에 보고하는 바이다.

• 한국동물위생학회지
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• 제41권3호
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• pp.133-139
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• 2018

Porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) are known as significant immunosuppressive viruses in pigs. In this study, we investigated the correlation of PCV2 and PRRSV in enteric lesions of porcine salmonellosis. A total of 64 cases were classified into four pig groups as group A (24 cases, S. Typhimurium), group B (11 cases, S. Typhimurium+PCV2), group C (16 cases, S. Typhimurium+PRRSV) and group D (13 cases, S. Typhimurium+PCV2+PRRSV). Comparing with group A, ulcerative enteritis in large intestine was little more prevalent in the PCV2 infected pigs in group B and D. And lymphoid depletion in gut-associated lymphatic tissue (GALT) of large intestine was also detected in PCV2 positive group B (36.4%) and D (30.8%). According to the results of immunohistochemistry (IHC), PCV2 antigens (83.3%) were more prevalently distributed in the intestinal lesions of porcine salmonellosis than PRRSV antigens (10.3%). PCV2 were also detected in the lymphoid depleted GALT of the large intestine from 7 of the 8 pigs (87.5%), but PRRSV were not found in all cases. It may explain that PCV2 can play a certain immunological role to enhance secondary bacterial infection in porcine alimentary tracts.

• Tuberculosis and Respiratory Diseases
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• 제43권5호
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• pp.779-785
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• 1996

저자 등은 두통과 비루를 주소로 내원한 46세 남자에서 비강, 폐, 신장을 침범하고, 양측 전경골 동맥과 비골 동맥 폐쇄를 동반한 베게너 육아종증 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제63권6호
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• pp.531-536
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• 2007

웨게너 육아종증은 중형내지 소형의 동맥과 정맥을 침범하는 전신적 혈관염의 한 형태로 상, 하부 기도 및 신장의 질환을 특징으로 한다. 신장에 국한된 질환으로 나타날 때에는 Henoch-$Sch\ddot{o}nlein$ 자반증, 현미경적 다발성 혈관염 등의 기타 신장 침범 혈관염과 구분하기 어렵다. 본 증례에서는 초기 신조직검사에서 IgA 양성으로 Henoch-$Sch\ddot{o}nlein$ 자반증으로 진단되고, 15년 후에 폐조직 검사에서 웨게너 육아종증으로 진단된 1예를 경험하였기에 문헌고찰과 함께 보고한다.