Recurrent Respiratory Papillomatosis improved by Treatment with Interferon-${\alpha}$

인터페론 치료로 호전을 보인 재발성 유두종증 1예

  • Kim, Ki Uk (Department of Internal Medicine, College of Medicine, Pusan National University) ;
  • Cho, Woo Hyun (Department of Internal Medicine, College of Medicine, Pusan National University) ;
  • Jung, Kyung Sik (Department of Internal Medicine, College of Medicine, Pusan National University) ;
  • Park, Hye Kyung (Department of Internal Medicine, College of Medicine, Pusan National University) ;
  • Lee, Jun Hee (Department of Internal Medicine, College of Medicine, Pusan National University) ;
  • Lee, Joung Wook (Department of Internal Medicine, College of Medicine, Pusan National University) ;
  • Lee, Jung Hyun (Department of Internal Medicine, College of Medicine, Pusan National University) ;
  • Kim, Yun Seong (Department of Internal Medicine, College of Medicine, Pusan National University) ;
  • Lee, Min Ki (Department of Internal Medicine, College of Medicine, Pusan National University) ;
  • Wang, Soo Geun (Department of Otolaryngology, College of Medicine, Pusan National University) ;
  • Park, Soon Kew (Department of Internal Medicine, College of Medicine, Pusan National University)
  • 김기옥 (부산대학교 의과대학 내과학교실) ;
  • 조우현 (부산대학교 의과대학 내과학교실) ;
  • 정경식 (부산대학교 의과대학 내과학교실) ;
  • 박혜경 (부산대학교 의과대학 내과학교실) ;
  • 이준희 (부산대학교 의과대학 내과학교실) ;
  • 이정욱 (부산대학교 의과대학 내과학교실) ;
  • 이정현 (부산대학교 의과대학 내과학교실) ;
  • 김윤성 (부산대학교 의과대학 내과학교실) ;
  • 이민기 (부산대학교 의과대학 내과학교실) ;
  • 왕수건 (부산대학교 의과대학 이비인후과학교실) ;
  • 박순규 (부산대학교 의과대학 내과학교실)
  • Published : 2003.03.30

Abstract

Recurrent respiratory papillomatosis(RRP) is a chronic disease that is caused by the human papillomavirus(HPV) type 6 and 11. The most common site of the lesions is the larynx, but papillomas can occur throughout the respiratory and upper gastrointestinal tracts. Frequent recurrence of disease, can result in airway compromise and even death when papillomas either obstruct the airway or spread to the lung parenchyma. We encountered a case of a recurrent respiratory papillomatosis in a 23-year-old patient, who improved after treatment with interferon-${\alpha}$ The patiented with hoarseness, exertional dyspnea, and a productive cough. We report this case with a brief review of the relevant literature.

저자들은 호흡곤란, 객담, 기침을 주소로 내원한 23세 남자환자에서 기관지 내시경 및 VATS로 시행한 조직검사상 후두와 함께 기관, 기관지 및 폐실질을 침범한 유두종증으로 진단받고 interferon-${\alpha}$ 치료 후 호전을 보인 재발성 호흡기계 유두종증 1예를 경험하였기에 보고하는 바이다.

Keywords