• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.1
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• pp.166-174
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• 2013

QRS detection of ECG is the most popular and easy way to detect cardiac-disease. But it is difficult to analyze the ECG signal because of various noise types. The important problem in recording ECG signal is a baseline wandering, which is occurred by rhythm of respiration and muscle contraction attaching to an electrode. Particularly, in the healthcare system that must continuously monitor people's situation, it is necessary to process ECG signal in realtime. In other words, the design of algorithm that exactly detects QRS region using minimal computation by analyzing the person's physical condition and/or environment is needed. Therefore, baseline wander removing method based on morphological filter for efficient QRS detection method is presented in this paper. For this purpose, we detected QRS through the preprocessing method using morphological filter, adaptive threshold, and window. The signal distortion ratio of the proposed method is compared with other filtering method. Also, R wave detection is evaluated by using MIT-BIH arrhythmia database. Experiment result show that proposed method removes baseline wanders effectively without significant morphological distortion.

• Journal of Biomedical Engineering Research
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• v.16 no.3
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• pp.353-358
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• 1995

The impedance pneumography which is widely used in monitoring respiration is simple to use and noninvasive, but it is sensitive to motion artifacts and insensitive to detect obstructive apnea. A 3-channel respiratory inductive plethysmography (RIP) developed in this study detects inductance change of the inductance band induced by cross-sectional area change of thorax or abdomen as one breathes. It was confirmed that RIP was less sensitive to various motion artifacts but more sensitive to detection of obstructive apnea than impedance pneumography.

• Journal of Microbiology and Biotechnology
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• v.25 no.1
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• pp.127-136
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• 2015

Cupredoxin-like proteins are mainly copper-binding proteins that conserve a typical rigid Greek-key arrangement consisting of an eight-stranded β-sandwich, even though they share as little as 10-15% sequence similarity. The electron transport function of the Cupredoxins is critical for respiration and photosynthesis, and the proteins have therapeutic potential. Despite their crucial biological functions, the identification of the distant Cupredoxin homologs has been a difficult task due to their low sequence identity. In this study, the overlapped conserved residue (OCR) fingerprint for the Cupredoxin superfamily, which consists of conserved residues in three aspects (i.e., the sequence, structure, and intramolecular interaction), was used to detect the novel Cupredoxin homologs in the NCBI non-redundant protein sequence database. The OCR fingerprint could identify 54 potential Cupredoxin sequences, which were validated by scanning them against the conserved Cupredoxin motif near the Cu-binding site. This study also attempted to model the 3D structures and to predict the functions of the identified potential Cupredoxins. This study suggests that the OCR-based approach can be used efficiently to detect novel homologous proteins with low sequence identity, such as Cupredoxins.

• Archives of Craniofacial Surgery
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• v.12 no.2
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• pp.121-124
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• 2011

Purpose: The congenital epulis is a rare, benign tumor. It can protrude out of the newborn's mouth to prevent normal closure of the mouth and it can interfere with respiration or feeding. Methods: An 11-day old female neonate presented with a $1.5\;{\times}\;1.5\;{\times}\;2.3cm$ sized mass in the gingival and anterior alveolar ridge of the mandible. We performed a simple excision. Results: In our case, histologically, there was no pseudoepitheliomatous hyperplasia. The staining for S-100 protein, and actin was negative. After 8 months, the patient had normal teeth eruption and no recurrence of the tumor. Conclusion: With early detection and appropriate treatment, we were able to help the baby avoid developing any dyspnea. Nursing was possible after the mass had been removed.

• ETRI Journal
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• v.45 no.1
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• pp.105-118
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• 2023

We tested the feasibility of automated discrimination of patients with panic disorder (PD) from healthy controls (HCs) based on multimodal physiological responses using machine learning. Electrocardiogram (ECG), electrodermal activity (EDA), respiration (RESP), and peripheral temperature (PT) of the participants were measured during three experimental phases: rest, stress, and recovery. Eleven physiological features were extracted from each phase and used as input data. Logistic regression (LoR), k-nearest neighbor (KNN), support vector machine (SVM), random forest (RF), and multilayer perceptron (MLP) algorithms were implemented with nested cross-validation. Linear regression analysis showed that ECG and PT features obtained in the stress and recovery phases were significant predictors of PD. We achieved the highest accuracy (75.61%) with MLP using all 33 features. With the exception of MLP, applying the significant predictors led to a higher accuracy than using 24 ECG features. These results suggest that combining multimodal physiological signals measured during various states of autonomic arousal has the potential to differentiate patients with PD from HCs.

• Nuclear Engineering and Technology
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• v.54 no.12
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• pp.4644-4651
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• 2022

Due to its short half-life, thoron gas has been assumed to have negligible health hazards on humans compared to radon. But, one of the decay products with a long half-life can make it to be transported to a long distance and to cause a severe internal dose through respiration. Since most commercial radon detectors can not discriminate thoron signals from radon signals, it is very common to overestimate radon doses which in turn result in biased estimation of lung cancer risk in epidemiological studies. Though some methods had been suggested to measure thoron and radon separately, they could not be used for real-time measurement because of CR-39 or LR-115. In this study, an effective method was suggested to measure radon and thoron separately from the free air. It was observed that the activity of thoron decreases exponentially due to delay time caused by a long pipe between two chambers. Therefore from two ion chambers apart in time, it was demonstrated that thoron and radon could be measured separately and simultaneously. We also developed a collimated alpha source and with this source and an SBD, we could convert the ion chamber reading to count rate in cps.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.19 no.9
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• pp.1010-1019
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• 2008

In this paper, we present a noise analysis and measurement results of a bio-radar system that can detect human heartbeat and respiration signals. The noise analysis including various phase noise effects is very important in designing the bio-radar system, since the frequency difference between the received signal and local oscillator is very small and the received power is very low. All of the noise components in a bio-radar system are considered from the point of view of SNR. From this analysis, it can be concluded that the phase noise due to antenna leakage is a dominant factor and is a function of range correlation. Therefore, the phase noise component with range correlation effect, which is the most important noise contribution, is measured using the measurement setup and compared with the calculated results. From the measurement results, our measurement setup can measure a closed-in phase noise of a free-running oscillator. Based on these results, it is possible to design a 2.4 GHz bio-radar system quantitatively which has a detection range of 50 cm and low power of 1 mW without additional PLL circuits.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.9
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• pp.2105-2112
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• 2010

The noise component of electrocardiogram is not distributed in a certain frequency band. It is expressed in various types of signals by rater's physical and environmental conditions. Particularly, since the baseline wander is occurred by the mixture of the original signal and 0 ~ 2 [Hz] range of the frequency components according to muscle constraction of part attaching to an electrode and respiration rythm, it makes the ECG signal analysis difficult. Several methods have been proposed to eliminate the wandering effectually. However, they have some problems. In some methods, the high processing time is required due to the computational complexity, while in other cases ECG signal morphology can be distorted. This paper suggests a simple and effective algorithm that eliminates baseline wander with low computational complexity and without distorting signal morphology. First, the algorithm detects and segments a baseline wandering interval using slope analysis and curve point detection, second, approximates the wandering in the interval as a sinusoid, and then subtracts the sinusoid from signal. Finally, ecg signals without baseline wander are obtained. In order to evaluate the performance of the algorithm, several ECG signals with baseline wandering in MIT/BIH ECG database 101, 111, 113, 234 record were chosen and applied to the algorithm. It is found that the algorithm removes baseline wanders effectively without significant morphological distortion.

• Journal of Advanced Navigation Technology
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• v.13 no.4
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• pp.482-489
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• 2009

This paper proposes a CW(Continuous-Wave) bio-radar applying a new adaptive noise canceller based on ALE(Adaptive Line Enhancer) which can remove the Gaussian noise and system noise. Recently the research works on this CW bio-radar which can be used to detect heartbeat and respiration are advanced by the university and research facility. Although the researches describe CW bio-radar not only is vulnerable for the Gaussian noise but also has a disadvantage of decreasing the heart-rate accuracy due to the noise, the researches do not demonstrate the effective method for removing the noise component in a baseband signal. In this paper, a CW bio-radar applying the new adaptive noise canceller based on ALE which can remove the noise component is proposed. This paper compares and analyzes the performance for increasing the heart-rate accuracy according to removing the Gaussian noise and system noise in the baseband signal through the quadrature receiver which can alleviate the demodulation sensitivity to target position.

• Quality Improvement in Health Care
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• v.14 no.1
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• pp.55-59
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• 2008

Background : The purpose of inner cannula is to protect the upper air way and permit air to pass freely, in addition, to provide endotracheal suction, artificial respiration and to maintain adequate oxygen saturation. The tube needs to be sterilized for maintenance and cleanness of air way and for prevention of bronchospasm. However, it has been reported that there is no guideline for sterilization and many hospitals conduct their own sterilization methods, for example, once a day(13's general hospital), three times a day(The Catholic University of Korea ST Mary's hospital) or even no cleansing. Consequently, the QI team of our hospital suggested the SOP(standard operating procedure) of sterilization and evaluate cost and time effect in nursing. Method : 1) Benchmarking of 13's neurosurgery department of general hospital in Seoul 2) Investigation of test records of sputum culture from patients with intubation for tracheotomy 3) Check of results of O2 Sat. monitoring to confirm of maintaining opened air way Result : 1) Improvement of process: decrease of excess sterilization of inner cannula (from 3 times a day to once a day) 2) Cost effects: saving over 10 million won per one year 3) Providing better nursing: time effects (30 min a day) permit to conduct more nursing activities Conclusion : It can get Cost and time effects in nursing with improved sterilization method of inner cannula. It needs to do research on improvement of the monthly exchange protocol of outer cannula and provide supporting data for the proper exchange schedule. The result of additional microorganism detection from patients with new process needs to be evaluated further more.