• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2167-2172
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• 2013

Lung cancer remains a major cause of morbidity and mortality worldwide, accounting for more deaths than any other cause. All the clinical practice guidelines recommended against routine screening for lung cancer have cited lack of robust evidence, at least until a few years back. However, the potential to screen lung cancers has received renewed interest due to superior performance of low dose CT (LD-CT) in detecting early stage cancers. The incremental costs and risks involved due to the invasive procedures in the screened population due to a high false positivity rate questions the use of LD-CT scan as a reliable community based screening tool. There is therefore an urgent need to find a less invasive and a more reliable biomarker that is crucial to increase the probability of early lung cancer detection. This can truly make a difference in lung cancer survival and at the same time be more cost and resource utilization effective. Sampling blood serum being minimally invasive, low risk and providing an easy to obtain biofluid, needs to be explored for potential biomarkers. This review discusses the use of circulatory miRNAs that have been able to discriminate lung cancer patients from disease free controls. Several studies conducted recently suggest that circulating miRNAs may have promising future applications for screening and early detection of lung cancer.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제8권2호
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• pp.567-582
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• 2014

The purpose of this study is to qualitatively identify the typologies and characteristics of the big data marketing strategy in major companies that are taking advantage of the big data business in Korea. Big data means piles accumulated from converging platforms such as computing infrastructures, smart devices, social networking and new media, and big data is also an analytic technique itself. Numerous enterprises have grown conscious that big data can be a most significant resource or capability since the issue of big data recently surfaced abruptly in Korea. Companies will be obliged to design their own implementing plans for big data marketing and to customize their own analytic skills in the new era of big data, which will fundamentally transform how businesses operate and how they engage with customers, suppliers, partners and employees. This research employed a Q-study, which is a methodology, model, and theory used in 'subjectivity' research to interpret professional panels' perceptions or opinions through in-depth interviews. This method includes a series of q-sorting analysis processes, proposing 40 stimuli statements (q-sample) compressed out of about 60 (q-population) and explaining the big data marketing model derived from in-depth interviews with 20 marketing managers who belong to major companies(q-sorters). As a result, this study makes fundamental contributions to proposing new findings and insights for small and medium-size enterprises (SMEs) and policy makers that need guidelines or direction for future big data business.

• Asian-Australasian Journal of Animal Sciences
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• 제16권2호
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• pp.257-260
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• 2003

A total of 135 F2 finishing pigs (65 barrows and 69 gilts) from resource population (Large White${\times}$Meishan) were slaughtered at about 87.8 kg BW. Contents of inosine acid (IMP) and carnine (HR) in muscle were assayed by HLPC and genetic parameters for IMP content and HR content were estimated using full sibs model. There was significant sex effect on IMP content(p<0.05), $3.561{\pm}0.077mg/g$ for gilt and $3.287{\pm}0.085mg/g$ for barrow. Heritability estimates for IMP and HR content were 0.127 and 0.357, respectively. The phenotypic correlation between IMP content and HR was 0.335, pH (A) 0.024, water lose rate (WLR) -0.069, intramuscular fat (IMF) -0.214, average marbling score (MARB) -0.143, average backfat measurements (AVBF) -0.084 and average color value (CV) -0.156, respectively. The result indicated that inosine acid content in meat might be retained or slightly improved by reducing backfat depth in pig breeding.

• 대한간호학회지
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• 제25권4호
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• pp.774-789
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• 1995

Due to the rapid socioeconomic development and the introduction of the national health insurance system the general population's need for health care and utilization of health care services have increased dramatically. As a result of this change. Korea is experiencing a shortage of health care facilities and health manpower, and this leads long wailing line at doctor's offices. One of the solutions of this problem could be home health care system for those who have minor health related problems. With this background, this study was conducted to look at the feasibility of a home-based prenatal care system using information superhighway and nursing informatics specialists. With the home-based prenatal care system, the pregnant woman checks her blood pressure, tests her urine for sugar and protein, and measures her body weight at home and sends the information to a hospital computer via the information networks such as public telephone line and information superhighway. Nursing informatics specialist at the hospital will go through each patient record and screen those who have abnormal values and notify them to see a doctor as soon as possible. Besides telemonitoring features, the proposed system will include tole-education capabilities for the patients so that patient can learn whatever they need to know ragarding the prenatal care via information networks. If this system develops and operates, patient can save time in terms of travel to and from the hospital and waiting time in the hospital. And the health care institute can utilize its resource more efficiently.

• 디지털융복합연구
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• 제11권5호
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• pp.257-265
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• 2013

창업실패에 대한 선행연구들은 상장기업의 도산원인을 도출하는데 주력하여 왔다. 본 연구에서는 창업기업을 대상으로 실패원인과 실패과정을 분석하고자 한다. 20개 창업기업의 실패사례를 바탕으로 신생의 어려움과 ERIS모델을 활용하여 창업실패 원인을 도출하였다. 국내 창업기업들에게는 경영능력 부족, 연구개발 및 제품화 실패, 판로 확보 어려움과 같은 신생의 어려움이 존재함을 발견하였다. 또한, 창업 실패과정을 사업준비 부족형, 자원획득 실패형, 전략부재형, 마케팅 실패형으로 유형화 하였다.

• 한국병원경영학회지
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• 제24권4호
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• pp.43-56
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• 2019

Purpose: Importance of patient satisfaction related to patient-centeredness has been emphasized, and it is known to have effect on various health outcomes including health resource utilization. However, the effect of patient satisfaction has been discussed mostly in terms of hospital marketing in Korea. This study aims to examine the effect of patient satisfaction in patient-physician communication on healthcare utilization in a nationally representative adult population of South Korea. Method: Patient satisfaction with physician communication is assessed using 4 items in the 2011 Korea Health Panel Survey. Generalized linear regression analysis is conducted using 9,325 adults' healthcare utilization in 2012. Findings: Adjusting for the socio-demographic, economic factors, individual health status, health behaviors and healthcare utilization in 2011, more satisfied individuals, more likely to utilize the outpatient service, especially in clinical setting. Practical Implications: The study findings suggests that in context of South Korea healthcare system such as insufficient medical consultation time and the absence of health delivery system, patient satisfaction as a subjective healthcare quality indicator would have effect on the individual's outpatient visit. This study contributes to stimulate patient satisfaction research and discussion in South Korea to further explore its relationship with potential and various health related outcomes. Further implications of the study are discussed.

• Animal Systematics, Evolution and Diversity
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• 제33권3호
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• pp.169-175
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• 2017

In the northwestern Pacific region, the pen shell (Atrina pectinata) is a widely distributed bivalve and economically important in fisheries. Recently, stock of this species has been greatly reduced due to overexploitation and marine pollution, which arouses interest in conservation. Studies on genetic and taxonomic entities of pen shells have not been tried in Korea, which makes difficult to take measures for effective conservation of this marine resource. In this study, we investigated mitochondrial genetic polymorphism of pen shells collected from 4 locations in Korea and Japan using cytochrome c oxidase I (COI) gene sequences. A total of 39 haplotypes were identified among 86 individuals of pen shell. Although only 5 haplotypes were shared, no significant genetic differentiation was observed between Korean and Japanese populations. These results suggest that pen shell populations of these regions share an ancestral population which might have experienced expansion during the Pleistocene, but gene flow must have been highly restricted after expansion.

• 보건의료산업학회지
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• 제11권3호
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• pp.79-90
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• 2017

Objectives : The purpose of this study was to identify the prevalence of malnutrition and to explore its association with socioeconomic and social support factors among Korean elderly in the community. Methods : The study sample was a weighted population of 10,160 elderly who participated in the 2014 Korean Elderly Living Conditions and Welfare Survey. Multiple logistic regression analyses were performed to assess the association socioeconomic and social support factors have with malnutrition. Results : Of the Korean elderly 18.6% were at risk of malnutrition. Being uneducated (OR=1.40) and having a lower household income (OR=1.97) were significantly associated with malnutrition even after adjusting for other socio-demographic and health-related covariates. Elderly who lived alone (OR=1.86) and who had poor relationships with their children (OR=1.97) were at much higher risk of malnutrition than their counterparts. Their having poor relationships with acquaintances and poor social participation were also associated with malnutrition. Conclusions : Socioeconomic and social support resources are important factors in the nutritional status of the elderly.

• 한국환경과학회지
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• 제9권6호
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• pp.449-454
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• 2000

Sustainable development has been the key concept, both in economic policies and in environmental management. On the basis of an systems ecology perspective, this suggests the sustainable development of Korea\`s natural environment and economic activity using the EMERGY evaluation. The total EMERGY use(7,730E20sej/yr) in Korea is 81 percent from imported sources, fuels and goods and services. The ratio of outside investment to attracting natural resources is already large, like other industrialized countries. Continued availability of purchased inputs at a favorable balance of EMERGY trade, currently about 2.85 to 1 net EMERGY, tis the basis for present economic activity and must decrease as the net EMERGY of purchased inputs including fossil fuels goes down. EMERGY yield ratio and environmental loading ratio were 1.23 and 20.30, respectively. The population level is already in excess of carrying capacity. Its carrying capacity for steady state on its renewable sources is only 2.2 million people, compared to 45.9 million in 1977. EMERGY sustainability index is therefore less than one, which is indicative of highly developed consumer oriented economies. Until now the development of a country has been achieved by the economic growth, but it can be sustained in the long run by the use of renewable resource systems. the efficiency of energy usage, and the transformation of the social-economic structure based on an ecological-recycling concept.

• Genomics & Informatics
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• 제12권3호
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• pp.121-126
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• 2014

Medication adherence is generally defined as the extent of voluntary cooperation of a patient in taking medicine as prescribed. Adherence to long-term treatment with chronic disease is essential for reducing disease comorbidity and mortality. However, medication non-adherence in chronic disease averages 50%. This study was conducted a genome-wide association study to identify the genetic basis of medication adherence. A total of 235 medication non-adherents and 1,067 medication adherents with hypertension or diabetes were used from the Korean Association Resource project data according to the self-reported treatment status of each chronic disease, respectively. We identified four single nucleotide polymorphisms with suggestive genome-wide association. The most significant single nucleotide polymorphism was rs6978712 (chromosome 7, $p=4.87{\times}10^{-7}$), which is located proximal to the GCC1 gene, which was previously implicated in decision-making capability in drug abusers. Two suggestive single nucleotide polymorphisms were in strong linkage disequilibrium ($r^2$ > 0.8) with rs6978712. Thus, in the aspect of decision-making in adherence behavior, the association between medication adherence and three loci proximal to the GCC1 gene seems worthy of further research. However, to overcome a few limitations in this study, defining the standardized phenotype criteria for self-reported adherence should be performed before replicating association studies.