• 정보관리학회지
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• 제21권3호
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• pp.99-123
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• 2004

전통적으로 학위논문은 우수한 학술 정보적 가치를 내포하고 있음에도 불구하고 물리적 이용가능성의 부재로 인하여 평가 절하되어 왔다. 이를 해소하려면 전자형 학위논문시스템의 개발이 필요하며, 그것은 정보탐색 과정에서 연구결과를 배포하는 기본 채널로 그리고 학위논문이 핵심자료임을 인식시키는 계기를 제공할 것이다. 그래서 최근에 각국의 많은 대학(도서관)이 디지털 환경에 부응할 목적으로 전통적(인쇄형) 학위논문을 전자버전으로 변환하고 있다. 이에 주목하여 본 연구는 웹 설문지와 홈페이지 조사방식으로 학위논문 관리시스템의 현황을 분석한 선행연구를 이론적 배경으로 삼아 국내 학위논문의 표준관리모형을 제안하였다.

• 한국균학회소식:학술대회논문집
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• 한국균학회 2014년도 추계학술대회 및 정기총회
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• pp.23-23
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• 2014

There are many yeast strains have been discovered for industrial usage in global scale. In the point of view for the alcoholic fermentation performance and producing alcoholic beverage products, recently many countries have known about the importance of microorganisms as a valuable resource. Discovered with well performed yeasts have potential industrial application in diverse ways such as foods, beverages, cosmetics, pharmaceutical functions, and so on. In Korea, the yeast research has not been sufficiently performed especially for distilled spirits industry. As a result, not so little manufacturers use exotic yeasts from overseas even included the expensive royalties. Besides of those, to produce distilled spirits, many manufacturers do not use specialized yeast for distilled spirits. Distiller's characterized yeasts such as whisky, brandy, vodka, Japanese shochu and awamori, are all well-known industrialized. For decades, the distillers, except us, have selected, developed, and practised yeasts in accordance with distilled spirits characters. This study is about selection and industrial application of yeasts for the Korean pot distilled spirits. Finally 7 yeast strains were selected among over 1,000 yeasts from the traditional Nuruks, through the essential related tests based on brewing and distilling science. The selected yeasts show the appropriate characteristics of distilled spirits. The result of this study could help our distilled spirits industry be activated and stand independent from the exotic microbes.

• Genomics & Informatics
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• 제12권4호
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• pp.225-230
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• 2014

Platelets are derived from the fragments that are formed from the cytoplasm of bone marrow megakaryocytes-small irregularly shaped anuclear cells. Platelets respond to vascular damage, contracts blood vessels, and attaches to the damaged region, thereby stopping bleeding, together with the action of blood coagulation factors. Platelet activation is known to affect genes associated with vascular risk factors, as well as with arteriosclerosis and myocardial infarction. Here, we performed a genome-wide association study with 352,228 single-nucleotide polymorphisms typed in 8,842 subjects of the Korea Association Resource (KARE) project and replicated the results in 7,861 subjects from an independent population. We identified genetic associations between platelet count and common variants nearby chromosome 4p16.1 ($p=1.46{\times}10^{10}$, in the KIAA0232 gene), 6p21 ($p=1.36{\times}10^{-7}$, in the BAK1 gene), and 12q24.12 ($p=1.11{\times}10^{-15}$, in the SH2B3 gene). Our results illustrate the value of large-scale discovery and a focus for several novel research avenues.

• 농업과학연구
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• 제47권2호
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• pp.283-290
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• 2020

In 2018, 647 thousand tons of eggs were produced and consumed. However, the issue of pesticides used for egg in 2017 made Korean consumers worry about the food safety of eggs, and the volume of egg consumption decreased. The Korean egg industry also has another problem due to an unclear and inefficient marketing structure at the farm level. This marketing situation of eggs at the farm level in Korea needs a large-scale restructuring of the market structure, including introducing an EPC (egg processing center). Especially, the introduction of an EPC has been discussed by government officers and specialists, but the social benefit of an EPC, which will be the driving point for approving an EPC, has not been measured yet. The purpose of this study was to measure the effect of introducing an EPC in Korea. Through an analysis using EDM (equilibrium displacement model), a few findings are presented. First, the introduction of an EPC may increase the transparency of price discovery and decrease the transaction cost. And thus, it results in a higher producer price, lower consumer price, and larger quantity at market equilibrium. Second, an EPC will improve the level of food safety of eggs, which can increase the satisfaction of domestic producers and consumers. Third, the introduction of an EPC may create new consumption of eggs. Based on these three effects, the new social benefits in monetary terms from the introduction of an EPC in Korea could be 23.9 - 35.2 billion won.

• 한국HCI학회논문지
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• 제8권1호
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• pp.11-17
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• 2013

Context aware systems are those systems that are aware about the environment and perform productive functions automatically by reducing human computer interactions(HCI). In this paper, we present common architecture principles of context-aware systems to explain the important aspects of context aware systems. Our study focuses on identifying common concepts in pervasive computing approaches, which allows us to devise common architecture principles that may be shared by many systems. The principles consists of context sensing, context modeling, context reasoning, context processing, communication modelling and resource discovery. Such an architecture style can support high degree of reusability among systems and allows for design flexibility, extensibility and adaptability among components that are independent of each other. We also propose a new architecture based on broker-centric middleware and using ontology reasoning mechanism together with an effective behavior based context agent that would be suitable for the design of context-aware architectures in future systems. We have evaluated the proposed architecture based on the design principles and have done an analyses on the different elements in context aware computing based on the presented system.

• 한국해양바이오학회지
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• 제3권1호
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• pp.24-30
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• 2008

Fishing in Kenya, until the discovery of Nile perch as an export commodity in the early 1990s, has basically a subsistence occupation for the lake and coastal communities. The government also did not recognize the importance of fisheries as a contributor to the macro-economy and therefore, did not pay much attention in terms of resource allocation for the development of the sector. Most fishing in Kenya is artisanal, with a little industrial fishing by prawn trawlers. The deep sea (EEZ) fishery resources are currently exploited by DWFNs through a licensing system. Only a small quantity of catch from the EEZ is landed in Kenya, primarily tuna loins for processing for export. Currently capture fisheries, mainly from Lake Victoria, earn local fishers over Kenya shillings (K Sh) 7 billion, while exports earn the country K Sh 5 billion (US$ 50 million) in foreign exchange annually. The government has been putting in place an enabling environment to promote investment activities in order to achieve economic recovery as well as for the development and sustainable use of fisheries resources in the country within the specified period. The Department's major roles are to ensure sustainable exploitation of fisheries resources; to promote aquaculture development; to assure quality and safety of fish and fishery products; and to facilitate fish marketing in order to maximize the benefits that can be derived from fisheries. The contribution of fisheries to local incomes, subsistence and food nutrition is significant, as this occurs in areas with the highest incidences of poverty in the country.

• Molecules and Cells
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• 제37권1호
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• pp.36-42
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• 2014

The tomato (Solanum lycopersicum L.) is a model plant for genome research in Solanaceae, as well as for studying crop breeding. Genome-wide single nucleotide polymorphisms (SNPs) are a valuable resource in genetic research and breeding. However, to do discovery of genome-wide SNPs, most methods require expensive high-depth sequencing. Here, we describe a method for SNP calling using a modified version of SAMtools that improved its sensitivity. We analyzed 90 Gb of raw sequence data from next-generation sequencing of two resequencing and seven transcriptome data sets from several tomato accessions. Our study identified 4,812,432 non-redundant SNPs. Moreover, the workflow of SNP calling was improved by aligning the reference genome with its own raw data. Using this approach, 131,785 SNPs were discovered from transcriptome data of seven accessions. In addition, 4,680,647 SNPs were identified from the genome of S. pimpinellifolium, which are 60 times more than 71,637 of the PI212816 transcriptome. SNP distribution was compared between the whole genome and transcriptome of S. pimpinellifolium. Moreover, we surveyed the location of SNPs within genic and intergenic regions. Our results indicated that the sufficient genome-wide SNP markers and very sensitive SNP calling method allow for application of marker assisted breeding and genome-wide association studies.

• 한국산학기술학회논문지
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• 제15권5호
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• pp.2821-2830
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• 2014

본 연구는 빠른 성장과 일자리 창출에 기여할 수 있는 고성장 산업군을 발굴하여 육성전략을 도출해 보고자 하였다. 이를 위해 고성장 산업군을 가젤산업이라고 명명하고 '사업체당 종사자수가 10인 이상이면서 최근 5년간 Birch 고용성장지수로 측정한 고용창출 기여도가 모집단 전체의 상위 10% 이내인 산업'이라고 정의하였다. 가젤산업의 정의에 따라 충남의 가젤산업을 105개 선정하고, 전국대비 충남 가젤산업의 경쟁력을 분석해보고 충남도내 각 시 군간 경쟁력 차이를 분석해 시사점을 도출하였다. 또한, 사업체규모계수(BQ)와 산업성장률(IG)을 개발하고 산업발전단계 유형화 방법을 고안하여 충남가젤산업의 산업발전단계별 육성전략을 제안하였다.

• Biomolecules & Therapeutics
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• 제29권1호
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• pp.98-103
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• 2021

The demand for natural substances with anti-melanogenic activity is increasing due to the recent interest in skin whitening. Intensive investigation on the culture broth of Streptomyces sp. SCO-736, a marine bacterium from the Antarctica coast, has led to the isolation of a new natural product named antaroide (1). The chemical structure was established through the interpretation of MS, UV, and NMR spectroscopic data. Antaroide is a nine-membered macrolide with lactone and lactam moieties. To investigate its applicability in skin whitening cosmetics, its anti-melanogenic activity in B16F10 murine melanoma cells was examined. As a result, antaroide displayed strong inhibitory activities against melanin synthesis and also attenuated the dendrite formation induced by the α-melanocyte stimulating hormone (α-MSH). Antaroide suppressed the mRNA expression of the melanogenic enzymes such as tyrosinase, TRP-1 and TRP-2. This suggests that it may serve as a transcriptional regulator of melanogenesis. Collectively, the discovery of this novel natural nine-membered macrolide and its anti-melanogenic activity could give new insights for the development of skin whitening agents.

• Fisheries and Aquatic Sciences
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• 제25권5호
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• pp.251-263
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• 2022

Sea cucumbers are worm-like, leathery bodied, benthic, marine organisms with a branched gonad. There are over 900 species, and these organisms are capable of changing their mechanical state, regenerating their small appendages, and digestive tract. Additionally, sea cucumbers possess both commercial and therapeutical value. Furthermore, it is thought that the metabolites these organisms possess may give rise to their therapeutical value. The use of sea cucumbers in therapy can be traced back to the Ming dynasty, where they were eaten for their tonic properties against constipation, hypertension, and rheumatism. A plethora of studies have been conducted, whereby different metabolites were extracted from sea cucumbers and tested for different therapeutic properties. Herein, we review and discuss the anti-cancer, anti-microbial, anti-coagulant, anti-diabetic, antioxidant, and anti-inflammatory properties of the sea cucumber by assessing literature on PubMed and Google Scholar. Furthermore, the genome and epigenome of these remarkable species is discussed. With the immense data supporting the therapeutic properties of sea cucumbers, further studies are warranted, in order to develop novel and innovative therapeutic compounds for the benefit of human health from these fascinating marine organisms.