• Bulletin of the Korean Chemical Society
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• v.33 no.6
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• pp.1890-1894
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• 2012

Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) have been implicated in the pathogenesis of rheumatoid arthritis, which is angiogenesis dependent. Antibody-based molecular imaging improves targeting, and antibody radiolabeling is useful for monitoring biological events $in$ $vivo$ $via$ PET or SPECT. We investigated the potential of molecular imaging to diagnose arthritis with VEGFR-2 $in$ $vivo$. The $^{123}I$-VEGFR-2 antibody was prepared by the iodogen tube method. The radioligand was injected into arthritic mice, and micro SPECT/CT was performed. The arthritic mice were examined by 4.7-T MRI and immunohistochemistry. The $^{123}I$-VEGFR-2 antibody showed high uptake in the arthritic region at 1 h postinjection on SPECT/CT but no uptake in the control animals after radioligand injection. In MR images, the arthritic tissue of the mice was correlated with regions labeled by the $^{123}I$-VEGFR-2 antibody. Immunohistochemical localization showed markedly increased expression of VEGFR-2 in the endothelial cells, fibroblasts, and macrophages of the arthritic mice.

• Structural Engineering and Mechanics
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• v.68 no.2
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• pp.203-213
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• 2018

This paper presents a study of geometric nonlinear forced vibration of carbon nano-tubes (CNTs) reinforcement composite plates on nonlinear elastic foundations. The plate is bonded with piezoelectric layers. The von Karman geometric nonlinearity assumptions with classical plate theory are employed to obtain the governing equations. The Galerkin and homotopy perturbation method (HPM) are utilized to investigate the effect of carbon nano-tubes volume fractions, large amplitude vibrations, elastic foundation parameters, piezoelectric applied voltage on frequency ratio and primary resonance. The results indicate that the carbon nano-tube volume fraction, applied voltage and elastic foundation parameters have significant effect on the hardening response of carbon nanotubes reinforced composite (CNTRC) plates.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.11 no.3
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• pp.33-38
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• 2002

This paper deals with pressure ripple attenuation far separated-type Hydrostatic Transmission (HST) consisting ova variable axial piston pump connected in an open loop to a fried displacement axial piston motor. Pressure ripples in HST is major source of vibration which can lead to fatigue failure of components and cause noise. In order to reduce the pressure ripple, an annular tube tripe hydraulic filter is proposed to attenuate pressure ripples with the high frequencies components to achieve better noise reduction in HST. The basic principle of a hydraulic filter is allied to propagation of pressure wave, reflection, absorption in cross section of discontinuity and resonance in the hydraulic pipeline. It is experimentally shown that the hydraulic filter attenuates about 30∼40dB of pressure ripple with high frequencies. These results will assist in modeling and design of noise reduction in hydraulic control systems, and provide a means of designing a quieter HST.

• Journal of Korean Neurosurgical Society
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• v.39 no.4
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• pp.310-313
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• 2006

Although lipomyelomeningocele and dermoid cyst are formed during a similar embryologic developmental stage of 'neural tube formation', they are caused by entirely different embryologic mechanisms. We encountered a case, which has not been previously reported, that had a lumbar subcutaneous dermoid cyst associated with lipomyelomeningocele. A 52-year-old man presented with a slowly growing lumbar mass of 3 years duration, which had been present since birth. Lumbosacral magnetic resonance imaging[MRI] showed lipomyelomeningocele at the L3, 4 and 5 levels and a subcutaneous cystic mass of high signal intensity on the T2 weighted image and iso or low signal intensity on the T1 weighted image. He underwent total resection of the lumbar subcutaneous mass. Intraoperative findings and histological examination were consistent with the preoperative diagnosis of a 'dermoid cyst'. We demonstrate that the formation of a dermoid cyst might coexist with lipomyelomeningocele during the embryologic developmental stage.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2003.04a
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• pp.117-123
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• 2003

This paper deals with pressure ripple and noise reduction characteristics for a hydrostatic transmission(HST) consisting of a variable axial piston pump connected in an open loop to a fixed displacement axial piston motor. Pressure ripples in HST is major source of vibration, which can lead to fatigue failure of components and cause noise. In order to reduce the pressure ripple, an annular tube type hydraulic filter proposes to absorb pressure ripples with the high frequencies components to achieve better noise attenuation in HST. The basic principle tube is applied to propagation of pressure wave, reflection, absorption in cross section of discontinuity and resonance in the hydraulic pipeline. It is experimently confirmed that a hydraulic filter is absorbed to be about 30∼40dB of pressure ripple with high frequencies. These results will assist in modeling and design of noise reduction in hydraulic control systems, and here, should provide a means of designing a quieter HST.

• Journal of Industrial Technology
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• v.24 no.A
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• pp.75-81
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• 2004

The metal halide lamps are now widely used in the application and commercial lighting due to their attracting properties such as good color rendering and high efficiency. But, they have the serious problem of acoustic resonance for high frequency operation and they need the high voltage to ignite. So, they have not been applied to indoors. Over the past few years, a considerable number of studies have been conducted on the electronic ballast together with hot restarting and resonance phenomenon. But, very few attempts have been made with the adaptive ignition method according to the lamp state. In this paper, electronic ballast is proposed for metal halide lamps with an igniter for adaptive ignition. The proposed electronic ballast can generate different ignition voltages according to the arc tube state.

• Proceedings of the KSME Conference
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• 2001.11b
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• pp.223-228
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• 2001

The thermoacoustic refrigerator has not only considerable possibility but also commercial usability, because it has high reliability, lower vibration, no moving part, and can easily be constructed. In this study, The thermoacoustic refrigerator were constructed. The apparatus is capable of driving closed systems containing He or air at mean pressures ranging from 1-9.3 bar, at frequencies ranging from 100-1000Hz. The resonance characteristics of the thermoacoustic refrigerator were investigated for better performance, The resonance tube is 340.5mm in length. In case of using air as a coolant. Freezing frequency is 174Hz, In case of using He as a coolant Freezing frequency is 625Hz. Using He, The cold-part temperature of the heat exchanger fell to $-23.7^{\circ}C$ after 120 minutes in 70W.

• Proceedings of the SAREK Conference
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• 2009.06a
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• pp.1277-1282
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• 2009

The main objective of this prototype is to control resonance frequency of DTL system through the temperature control of cooling water. It is to resonant frequency of the drift tube cavities to 350 MHz. This paper describes the design of a prototype cooling water skid required for the temperature control of the DTL cavities, focusing in the modeling and simulation of the cooling system, the sizing of water pumping skid component.

• Proceedings of the Korean Society of Marine Engineers Conference
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• 2012.06a
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• pp.184-184
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• 2012

Recently, as a result of the application of large and multi-blade propellers with high efficiency for large vessels, the vertical bending stiffness of propulsion shafting system tends to be declined. For some specific vessels, the shaft arrangement leads to the forward stern tube bearing to be omitted, decreasing vertical bending stiffness. In this respect, decreased vertical bending stiffness causes the problem which is the blade order resonance frequency to be placed within the operational range of propulsion shafting system. To verify whirling vibration, the measurement should be carried out covering the range of MCR, however, the range is un-measurable. To resolve the measurement issue, this study shows the measuring method and the estimating method of whiling vibration by using resonance frequency of sub harmonic.

• Nuclear Engineering and Technology
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• v.32 no.3
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• pp.254-260
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• 2000

Electron spin resonance (ESR) spectroscopy was used to detect irradiated meat containing bones (chicken, pork and beef）, to investigate the effect of irradiation dose on the ESR signal intensity and to identify the stability of radicals under 9 weeks of storage. Chicken, pork and beef were irradiated with doses 0, 1, 3, 5 and 7 kGy at room temperature using a Co-60 irradiator. Bones were pieced and dried, which were placed in a quartz tube within an Electron paramagnetic resonance (EPR) spectrometer resonator cavity. The irradiated bone presented an asymmetric absorption in shape, different from that of a non-irradiated one. The signal intensity of smaller animals are lower than larger species. Variation was observed between samples of the same species depending on the calcification status of the bone. Moreover different irradiation doses produced different signal areas that make possible to estimate the absorbed dose of treated meat. The ESR signal stability after irradiation was stable in even after a 9 week storage at room temperature.