• Journal of the Korean Magnetic Resonance Society
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• v.24 no.2
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• pp.53-58
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• 2020

Free radicals including reactive oxygen species (ROS) are important chemicals in the research area of biology, pharmaceutical, medical, and environmental science as well as human health risk assessment as they are highly involved in diverse metabolism and toxicity mechanisms through chemical reactions with various components of living bodies. Electron spin resonance (ESR) spectroscopy is a powerful tool for detecting and quantifying those radicals in biological environments. In this work we observed the ESR signal of 2,2,6,6-Tetra-methyl piperidine 1-oxyl (TEMPO) in aqueous solution at various concentrations to estimate the uncertainty factors arising from the experimental conditions and signal treatment methods. As the sample position highly influences the signal intensity, dual ESR tube geometry (consists of a detachable sample tube and a position fixed external tube) was adopted. This type of measurement geometry allowed to get the relative uncertainty of signal intensity lower than 1% when triple measurements are averaged. Linear dependence of signal intensity on the TEMPO concentration, which is required for the quantification of unknown sample, could be obtained over a concentration range of ~10³ by optimizing the signal treatment method depending on the concentration range.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.21 no.8
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• pp.720-725
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• 2011

Most ultrasonic vibration cutting tools are operated at the resonance condition of the longitudinal vibration of the structure consisting of booster, horn and bite. In this study, a transverse vibration tool with beam shape is designed to utilize the vibration characteristics of the beam. Design point of the transverse vibration tool is to match the resonance frequency of the bite to the frequency of the signal to excite the piezoelectric element in the booster. The design process to match the natural frequency of the longitudinal vibration mode of the horn and that of the transverse vibration mode of the bite is presented. Dimensions of the horn and bite are searched by trend analysis through which the standard shapes of the horn and bite are determined. After the dimensions of each component of the cutting tool consisting of booster, horn and bite are determined, the assembled structure was experimentally tested to verify that true resonant condition is achieved and proper vibrational displacement are obtained to ensure that enough cutting force is generated.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.21 no.4
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• pp.335-340
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• 2008

In this study, novel structured thin ultrasonic rotary motor has been proposed. Ultrasonic motors are based on an elliptical motion on the surface of elastic body. Thin brass plate was used as a cross shaped vibrator and eight ceramic plates were attached on upper side and bottom side of the brass plate. From the thin stator, elliptical displacements of the four contact tips were obtained. To find the optimal size of the stator, motions of the motors were simulated using ATILA by changing length, width and thickness of the ceramics. The stators had commonly three resonance peaks and contact tips of the stator moved on tangential or normal trajectories at these resonance peaks. The maximum displacements at the resonance peaks were compared. As results, maximum displacements of the contact tips were obtained at the length of 16 mm, width of 6 mm and thickness of 0.4 mm. Changes of the resonance frequencies were inversely proportional to the length of ceramic and proportional to the width of ceramic. The motor was fabricated by using the designed stator. And, the characteristics of the motor were compared with the simulated results. When the motor was fabricated with these results, speed fo 935 rpm was obtained by input voltage of 25 Vrms at 93.5 kHz.

• Journal of the Optical Society of Korea
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• v.13 no.3
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• pp.392-397
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• 2009

We designed a wavelength interrogation-based surface plasmon resonance (SPR) biosensor to detect avian influenza DNA (AI-DNA). Hybridization reactions between target AI-DNA probes and capture probes immobilized on a gold surface were monitored quantitatively by measuring the resonance wavelength in the visible waveband. The experimental results were consistent with numerical calculations. Although the SPR detection technique does not require the DNA to be labeled, we also evaluated fluorescently-labeled targets to verify the hybridization behavior of the AI-DNA. Changes in resonance were found to be linearly proportional to the amount of bound analyte. A wavelength interrogation-type SPR biosensor can be used for rapid measurement and high-throughput detection of highly pathogenic AI viruses.

• Korean Journal of Materials Research
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• v.17 no.5
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• pp.289-292
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• 2007

Although piezoelectric bimorph that is using as the sensor in medical and industrial measurement has large displacement, it has problems including efficiency in generating force, energy convergence, and response. Its application is being limited based on the change in resonance frequency with temperature. In this study, to overcome the disadvantages, PZT piezoelectric ceramics was prepared and produced a parallel type piezoelectric bimorphs. In addition, by using the finite element method. the configuration of piezoelectric bimorph was designed and the displacement of the bimorph based on applied electric pressure and the wave pattern were measured. By analyzing the resonance characteristics of the bimorph in the temperature range of $-60{\sim}80^{\circ}C$, an attempt was made to study the operational characteristics and temperature reliability of vortex flowmeter sensor. As a result, the resonance frequency of the bimorph was gradually increased with the temperature from $-60{\sim}80^{\circ}C$. The deflection of the bimorph was found to strongly depend on both the applied electric field waveform and the environmental temperature.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.6 no.2
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• pp.13-22
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• 2011

Objectives : The purpose of this study is to find out the characteristics of intervertebral disc changes and relative factors of the spondylolisthesis patients in fifties by type of spondylolisthesis. Methods : We investigated 69 cases of patients who visited one Korean traditional medicine hospital and were diagnosed as spondylolisthesis on L-spine X-ray and L-spine magnetic resonance imaging(MRI). We selected 37 lytic spondylolisthesis patients and 32 degenerative spondylolisthesis patients. We analysed the relativity between the numbers of changed discs, types of changed disc, locations of nerve compression and types of spondylolisthesis. Results : 1. The number of changed discs increase in lytic type, but there is no statistically significant difference. 2. Bulging disc is the dominant type of disc change. There is no significant difference between two types. 3. Both foraminal type was shown dominantly in lytic spondylolisthesis, diffuse type in degenerative spondylolisthesis by the analysis of the location of the nerve compression. But the symptoms of patients and dermatome did not match in most of the cases. Conculsions : The direction of nerve compression is different while the disc changing aspects are similar in both types. In several spondylolisthesis patients in fifties, symptoms of patient are related to degeneration of vertebrae, not to the type of spondylolisthesis.

• Journal of Korean Medicine Rehabilitation
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• v.21 no.4
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• pp.119-130
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• 2011

Objectives: The purpose of this study is to find cut the characteristics of intervertebral disc changes arid relative factors of the patients with spondylolisthesis. Methods: We investigated 95 cases of patients who visited one Korean traditional medicine hospital and were diagnosed as spondylolisthesis on lumbar spine X-ray and lumbar spine magnetic resonance imaging(MRI). We selected these cases retrospectively and randomly. We analysed the relativity between number of changed discs and type of change disc and age, level of spondylolisthesis and type of spondylolisthesis. Results: 1. The number of changed discs increased with older and degenerative spondylolisthesis type(p<0.05) and was not related to the level of spondylolisthesis. 2. Bulging disc is the dominant type of disc change(74.12%). The type of changed disc was shown to be similar in lytic and degenerative spondylolisthesis. It was not relative to the level of spondylolisthesis(p>0.05). 3. The direction of nerve compression was diffuse type in about halfly of the patients(47.06%) and the symptoms of patent and dermatome did not matched in 54 cases. Conclusions: The patients who visited a Korean medicine hospital and were diagnosed as spondyolithesis have different characteristics from the established studies. Their discs changed dominantly to diffuse bulging type and the symptoms of patient were not related with the direction and level of the changed discs were spondylolisthesis existed.

• Journal of Magnetics
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• v.10 no.3
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• pp.122-127
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• 2005

New classes of LC resonators for micro magnetic sensor device were proposed and fabricated. The first type LC resonator (Type I) consists of a small piece of microwire and two cylindrical electrodes at the end of the microwire without direct contact to its ferromagnetic core. In type I resonator the ferromagnetic core of the microwire and cylindrical electrodes act as an inductor and two capacitors respectively to form a LC circuit. The second type LC resonator (Type II) consists of a solenoidal micro-inductor with a bundle of soft magnetic microwires as a core. The solenoidal micro-inductors fabricated by MEMS technique were $500\sim1,000\;\mu{m}$ in length with $10\sim20$ turns. A capacitor is connected in parallel to the micro-inductor to form a LC circuit. A tiny glass coated $CO_{83.2}B_{3.3}Si_{5.9}Mn_{7.6}$ microwire was fabricated by a glass-coated melt spinning technique. A supergiant magneto-impedance effect was found in a type I resonator as much as 400,000% by precise tuning frequency at around 518.51 MHz. In type II resonator the changes of inductance as a function of external magnetic field in micro-inductors with properly annealed microwire cores were varied as much as 370%. The phase angle between current and voltage was also strongly dependent on the magnetic field. The drastic increments of magnetoimpedance at near the resonance frequency were observed in both types of LC resonators. Accordingly, the sudden change of the phase angle, as large as $180^{\circ}C$, evidenced the occurrence of the resonance at a given external magnetic field.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.32 no.8
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• pp.654-659
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• 2008

This paper is to suggest a concept design of the permanent magnet type magnetic resonance imaging (MRI) device based on the parameter optimization method. Pulse currents in the gradient coils will introduce the effect of eddy currents in the ferromagnetic material, which will worsen the quality of imaging. In order to equalize the magnetic flux in the MRI device for good imaging, the eddy current effect in the ferromagnetic material must be taken into account. This study attempts to use the design of experiment (DOE) and the response surface method (RSM) for equalizing the magnetic flux of the permanent magnet type MRI device using that the magnetic flux can be calculated directly using a commercial finite element analysis package. As a result, optimal shapes of the pole and the yoke of the PM type MRI device can be obtained. The commercial package, ANSYS, is used for analyzing the magnetic field problem and obtaining the resultant magnetic flux.

• Journal of the Korean Magnetic Resonance Society
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• v.7 no.1
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• pp.37-45
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• 2003

Human CD99 is a ubiquitous 32-kDa transmembrane protein encoded by mic2 gene. Recently it has been reported that expression of a splice variant of CD99 transmembrane protein (Type I and Type II) increases invasive ability of human breast cancer cells. To understand structural basis for cellular functions of CD99 Type II, we have initiated studies on hCD99$\^$TMcytoI/ using circular dichroism (CD) and multi-dimensional NMR spectroscopy. CD spectrum of hCD99$\^$TMytoI/ in the presence of 200mM DPC and CHAPS displayed an existence ${\alpha}$-helical conformation, showing that it could form an ${\alpha}$-helix under membrane environments. In addition, we have found that the cytoplasmic domain of CD99 would form symmetric dimmer in the presence of transmembrane domain. Although it has been rarely figured out the correlation between structure and functional mechanism of hCD99$\^$TMcytoI/, the dimerization or oligomerization would play an important role in its biological function.