• Investigative Magnetic Resonance Imaging
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• v.11 no.2
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• pp.95-102
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• 2007

Purpose: To acquire high-resolution spiral-scan images at higher magnetic field, high homogeneous magnetic field is needed. Field inhomogeneity mapping and in-vivo shimming are important for rapid imaging such as spiral-scan imaging. The rapid scanning sequences are very susceptible to inhomogeneity. In this paper, we proposed a higher-order shimming method to obtain homogeneous magnetic field. Materials and Methods: To reduce measurement time for field inhomogeneity mapping, simultaneous axial/ sagittal, and coronal acquisitions are done using multi-slice based Fast Spin echo sequence. Acquired field inhomogeneity map is analyzed using the spherical harmonic functions, and shim currents are obtained by the multiplication of the pseudo-inverse of the field pattern with the inhomogeneity map. Results: Since the field inhomogeneity is increasing in proportion to the magnetic field, higher order shimming to reduce the inhomogeneity becomes more important in high field imaging. The shimming technique in which axial, sagittal, and coronal section inhomogeneity maps are obtained in one scan is developed, and the shimming method based on the analysis of spherical harmonics of the imhomogenity map is applied. The proposed technique is applicable to a localized shimming as well. High resolution spiral-scan imaging was successfully obtained with the proposed higher order shimming. Conclusion: Proposed pulse sequence for rapid measurement of inhomogeneity map and higher order shimming based on the inhomogeneity map work very well at 3 Tesla MRI system. With the proposed higher order shimming and localized higher order shimming techniques, high resolution spiral-scan images are successfully obtained at 3 T MRI system.

• Journal of Biomedical Engineering Research
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• v.32 no.2
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• pp.158-164
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• 2011

Breast cancer is the most frequently appearing cancer in women, these days. To reduce mortality of breast cancer, periodic check-up is strongly recommended. X-ray mammography is one of powerful diagnostic imaging systems to detect 50~100 um micro-calcification which is the early sign of breast cancer. Although x-ray mammography has very high spatial resolution, it is not easy yet to distinguish cancerous tissue from normal tissues in mammograms and new tissue characterizing methods are required. Recently ultrasound elastography technique has been developed, which uses the phenomenon that cancerous tissue is harder than normal tissues. However its spatial resolution is not enough to detect breast cancer. In order to develop a new elastography system with high resolution we are developing x-ray elasticity imaging technique. It uses the small differences of tissue positions with and without external breast compression and requires an algorithm to detect tissue displacement. In this paper, computer simulation is done for preliminary study of x-ray elasticity imaging. First, 3D x-ray breast phantom for modeling woman's breast is created and its elastic model for FEM (finite element method) is generated. After then, FEM experiment is performed under the compression of the breast phantom. Using the obtained displacement data, 3D x-ray phantom is deformed and the final mammogram under the compression is generated. The simulation result shows the feasibility of x-ray elasticity imaging. We think that this preliminary study is helpful for developing and verifying a new algorithm of x-ray elasticity imaging.

• Current Optics and Photonics
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• v.4 no.3
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• pp.193-199
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• 2020

In this paper we propose a dark-field digital holographic microscopy system based on 360-degree oblique illumination. This setup is constructed without using a dark-field objective. The principle of 360-degree oblique illumination of vortex beam and dark-field digital holographic microscopy are introduced theoretically and experimentally. By analyzing the reconstructed image of a dark-field digital hologram of a USAF 1951 target, it is proved that the imaging resolution can be improved by this method. And also, comparison and analysis are made on the reconstructed image of a bright-dark field digital hologram of a pumpkin stem slice, the result shows that the imaging contrast is also enhanced with this method, and it is effective for dark-field digital holographic microscopy imaging of large transparent biological samples.

• Proceedings of the KSRS Conference
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• 2005.10a
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• pp.482-484
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• 2005

The Modulation Transfer Function (MTF) is commonly used to characterize the spatial quality of imaging systems. This work is the attempt to measure the MTF at Nyquist frequency of the satellite imaging system what has 1m spatial resolution for KOMPSAT-2 image using the edge function. Artificial tarp targets are used in this study. A type of this tarp edge consists of two adjacent uniform bright and dark sides commonly used to test the performance of an optical system in edge function. The results from this work demonstrate the potential applicability of this method to estimate the response characteristics for KOMPSAT-2 that is scheduled to be launched.

• Journal of the Optical Society of Korea
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• v.20 no.1
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• pp.88-93
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• 2016

Recently laser speckle contrast (LSC) imaging has become a widely used optical method for in vivo assessment of blood flow in the animal brain. LSC imaging is useful for monitoring brain hemodynamics with relatively high spatio-temporal resolution. A speckle contrast imaging system has been implemented with electrical sensory stimulation apparatus. LSC imaging is combined with optical intrinsic signal imaging in order to measure changes in cerebral blood flow as well as neural activity in response to electrical sensory stimulation applied to the hindlimb region of the mouse brain. We found that blood flow and oxygen consumption are correlated and both sides of hindlimb activation regions are symmetrically located. This apparatus could be used to monitor spatial or temporal responses of cerebral blood flow in animal disease models such as ischemic stroke or cortical spreading depression.

• Journal of the Optical Society of Korea
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• v.17 no.5
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• pp.405-409
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• 2013

In this paper, a unifying framework to evaluate the depth resolution of axially distributed image sensing (ADS) systems under fixed resource constraints is proposed. The proposed framework enables one to evaluate the system performance as a function of system parameters such as the number of cameras, the number of pixels, pixel size, and so on. The Monte Carlo simulations are carried out to evaluate ADS system performance as a function of system parameters. To the best of our knowledge, this is the first report on quantitative analysis of ADS systems under fixed resource constraints.

• International Journal of Contents
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• v.14 no.3
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• pp.1-6
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• 2018

For 3D display applications, auto-stereoscopic display methods that can provide 3D images without glasses have been actively developed. This paper is concerned with developing a display system for elemental images of real space using integral imaging. Unlike the conventional method, which reduces a color image to the level as much as a generated depth image does, we have minimized original color image data loss by generating an enlarged depth image with interpolation methods. Our method was efficiently implemented by applying a GPU parallel processing technique with OpenCL to rapidly generate a large amount of elemental image data. We also obtained experimental results for displaying higher quality integral imaging rather than one generated by previous methods.

• The Journal of the Acoustical Society of Korea
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• v.29 no.2E
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• pp.73-85
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• 2010

In the diagnostic ultrasound (US) transducer technology, the high frequency US(HFUS) transducer over 20 MHz is one of the current issues to be pursued for better resolution with the expense of penetration. HFUS single element transducers and the mechanical scanning systems for imaging are reviewed, and HFUS array transducers are also briefly summarized. HFUS applications such as the human applications in ophthalmology and dermatology and small animal applications for research purposes are reviewed with vascular and blood imaging in this paper.

• Journal of the Korean Society for Precision Engineering
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• v.15 no.3
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• pp.99-106
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• 1998

Recently, scientists introduced a new type of microscope capable of investigating nonconducting surfaces in an atomic scale, which is called AFM (Atomic Force Microscope). It was an innovative attempt to overcome the limitation of STM (Scanning Tunnelling Microscope) which has been able to obtain the image of conducting surfaces. Surfaces of samples are imaged with atomic resolution. The AFM is an imaging tool or a profiler with unprecedented 3-D resolution for various surface types. The AFM technology, however, leaves a lot of room for improvement due to its delicate and fragile probing mechanism. One of the room for improvements is gap control between probe tip and sample surface. Distance between probe tip and sample surface must be kept in below one Angtrom in order to measure the sample surface in Angstrom resolution. In this paper, AFM system modeling, experimental system identification and control scheme based on system identification are performed and finally sample surface is measured by home-built AFM with such a control scheme.

• Journal of the Korean Institute of Telematics and Electronics
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• v.17 no.3
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• pp.26-35
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• 1980

The degradation of image due to the finite size of sensing devices has been one of the problems in all digital imaging systems. The basic study on the improvement of the spatial resolution was carried out in both spatial and frequency domains by the resolution recovery techniques which have been used in optics. Here, the techniques were applied to CT (Computerized Tomography) system, and image with finer resolution was obtained by these techniques. The basic theory is described and the results of the simulation are shown.