• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.4
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• pp.592-601
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• 2015

Rubus coreanus is known as Korean black raspberry, native to Korea, Japan, and China. Preliminary studies evaluating their potential for cancer treatment in mammalian test systems are ongoing. In recent years, interest has been renewed due to their high levels of anthocyanins. Anthocyanins in black raspberry are important due to their potential health benefits as dietary antioxidant, anti-inflammatory compound, and as a chemopreventive agent. In the present study, Saccharomyces cerevisiae BA29 was isolated from black raspberry fruit and fruit juice as a biogenic amine non-producing strain for manufacturing of black raspberry wine, after which we investigated its characteristics: biogenic amine-producing ability, cell growth ability, alcohol-fermentation ability, and resistance to alcohol, glucose, and sulfur dioxide. Based on preliminary experiments, we optimized culture medium compositions for improving dried cell weight of S. cerevisiae BA29 by response surface methodology (RSM) as a statistical method. Design for RSM used a central composite design, and molasses with the industrial applicability was used as a carbon source. Through statistical analysis, we obtained optimum values as follows: molasses 200 g/L, peptone 30 g/L, and yeast extract 40 g/L. For the model verification, we confirmed about 3-fold improvement of dried cell weight from 6.39 to 20.9167 g/L compared to basal yeast peptone dextrose medium. Finally, we manufactured black raspberry wine using S. cerevisiae BA29 and produced alcohol of 20.33%. In conclusion, S. cerevisiae isolated from black raspberry fruit and juices has a great potential in the fermentation of black raspberry wine.

• Journal of Microbiology and Biotechnology
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• v.18 no.3
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• pp.591-599
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• 2008

A murine model immunized by systemic and mucosal delivery of plasmid DNA vaccine expressing glycoprotein B (pCIgB) of pseudorabies virus (PrV) was used to evaluate both the nature of the induced immunity and protection against a virulent virus. With regard to systemic delivery, the intramuscular (i.m.) immunization with pCIgB induced strong PrV-specific IgG responses in serum but was inefficient in generating a mucosal IgA response. Mucosal delivery through intranasal (i.n.) immunization of pCIgB induced both systemic and mucosal immunity at the distal mucosal site. However, the levels of systemic immunity induced by i.n. immunization were less than those induced by i.m. immunization. Moreover, i.n. genetic transfer of pCIgB appeared to induce Th2-biased immunity compared with systemic delivery, as judged by the ratio of PrV-specific IgG isotypes and Th1- and Th2-type cytokines produced by stimulated T cells. Moreover, the immunity induced by i.n. immunization did not provide effective protection against i.n. challenge of a virulent PrV strain, whereas i.m. immunization produced resistance to viral infection. Therefore, although i.n. immunization was a useful route for inducing mucosal immunity at the virus entry site, i.n. immunization did not provide effective protection against the lethal infection of PrV.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.6
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• pp.2381-2391
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• 2013

In general, ground's thermal properties, types of heat exchanger, operational method, thermal interference between piles can be considered as key factors which affect the thermal performance of energy pile. This study focused on the effect of these factors on the performance by a numerical model reflecting a real ground condition. Depending on the degree of saturation of ground, pile's heat transfer rate showed a maximum difference of three times, and the thermal resistance of pile made a maximum difference of 8.7%. As for the type of heat exchanger effects on thermal performance, thermal efficiency of 3U type energy pile had a higher value than those of W and U types. The periodic operation (8 hours operation, 16 hours pause) can preserve about 20% of heat efficiency compared to continuous operation, and hence it has an advantage of preventing the thermal accumulation phenomenon. Thermal interference effect in group piles may vary depending on the ground condition because the extent decreases as the ground condition varies from saturated to dry. The optimal separation distance that maintains the decreasing rate of heat efficiency less than 1% was suggested as 3.2D in U type, 3.6D in W type, and 3.7D in 3U type in a general ground condition.

• Journal of the Korea Concrete Institute
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• v.24 no.6
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• pp.659-666
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• 2012

To secure the thermal crack resistance of mass concrete, researches and the field applications of low heat portland cement (LPC), ternary blended cement (TBC) which is produced by blending ordinary portland cement with blast furnace slag and fly ash, and early strength low heat blended cement (EBC) increased in recent years. Although the model for adiabatic temperature rise is necessary for estimating the risk of thermal cracking of concrete structures, sufficient data have not been accumulated for these mixtures. In addition, the differences in adiabatic test results have been reported for the volume of test specimens. Therefore, the present study evaluated the characteristics of adiabatic temperature rise based on the type of binder and the volume of the adiabatic test specimen. Test results indicated that the maximum temperature rise ($Q_{\infty}$) and the reaction factor (r) of TBC were the lowest. Test results also showed that $Q_{\infty}$ and r changed with respect to the volume of test specimen. $Q_{\infty}$ and r obtained from 6l equipment were lower than those of 50l equipment. Therefore, corrections with respect to this phenomenon was confirmed and the corrections factors are presented.

• The Journal of the Korea Contents Association
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• v.12 no.10
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• pp.254-279
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• 2012

This research aims to suggest a practical solution in order to make marriage immigrant women free from violence and stand on their own. The suggestion could be made by developing Substantive theory in terms of marriage immigrant women's coping with domestic violence. The research question is; How marriage immigrant women cope with domestic violence. The research used a route theory approach, and 11 of marriage immigrant women who have ever suffered from domestic violence participated in it. The research question used semi-structured open questions. As a result of paradigm model analysis, "mental and physical devastation" is defined as a core phenomenon, and causative conditions are "wheel of pain" and "helpless victims of violence". Besides, context conditions are "period growth with solitariness", "irrational marriage" and "indifferent reality". "Mental and physical devastation", the core phenomenon act and interact with effect of mediatory conditions; which are "social help", "cultural difference" and "helplessness". Here the action and reaction appear as "adaptation", "resistance", "self-protection" and "self-reinforcement", and the outcomes show up as "maintaining reality", "decision making" and "beginning a new life". "Coping with mental and physical devastation and standing on one's own feet" could be introduced as a core category. Process of coping with domestic violence presents its levels as; shocks ${\rightarrow}$ endurance ${\rightarrow}$ regret ${\rightarrow}$ overcoming. There are three patterns of coping, which are; "preserving realities", "returning", and "groping for the future".

• Journal of The Korean Association of Information Education
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• v.16 no.4
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• pp.383-395
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• 2012

This study investigated the recognition of teachers on the introduction and use of SMART education, which is an ICT-based customized learning method. Through the investigation, the study was to empirically examine the relationship between the use intention of SMART education and its influential factors, and analyze the difference in the use intention of SMART education by teachers, focusing on the experience of SMART education. For analysis purpose, a structural equation model, which was expanded from the theory of reasoned action, was presented. In addition, the difference in path coefficient, which affects the use intention of SMART education, was compared based on the experience with or without SMART education. The results showed that teacher efficacy in the teacher group without SMART education experience was more negatively significant in class burden. In the teacher group with SMART education experience, it was found that the attitude toward SMART education was more significant in use intention; organizational citizenship behavior was more significant in use intention; teacher efficacy was more significant in the attitude toward SMART education and; teacher efficacy was more significant in organizational citizenship behavior. No significant difference was found in the path coefficient among the groups in other hypotheses. Through these results, the factors for introducing and promoting SMART education and its invigoration measures were presented.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.28 no.6
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• pp.589-597
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• 2015

In this paper, the live load model for the design of high-speed railway bridge is analyzed by statistic and probabilistic methods and the safety level that is given by the load factors of the load combination is analyzed. This study is a part of the development of the limit state design method for the railway bridge, and the train data collected from the Gyeongbu high-speed railway for about one month are utilized. The four different statistical methods are applied to estimate the design load to match the bridge design life and the results are compared. In order to examine the safety level that the design load combination of the railway bridge gives, the reliability indexes are determined and the results are analyzed. The load effect from the current design live load for the high-speed rail bridge which is 0.75 times of the standard train load is came out greater than at least 30-22% that from the estimated load from the measured data. If it is judged based on the ultimate limit state, there is a possibility of additional reduction of the safety factors through the reliability analysis.

• Journal of Distribution Science
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• v.13 no.9
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• pp.59-70
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• 2015

Purpose - This study aims to suggest strategies for Korean enterprises advancing into the Vietnam bakery market by analyzing the effects of perceived values on brand preference and purchase intention among Korean and Vietnamese consumers. Research design, data, and methodology - The perceived value model designed includes functional (price, quality), emotional, and social values. The survey collected data from 500 consumers in Seoul (Korea) and HoChiMinh (Vietnam). The SPSS 18.0 package was used for analysis. Results - First, among Vietnamese consumers, perceived value had a positive (+) effect on global brand preference in the order of functional value of quality, social value, and the functional value of price. However, from an ethnocentric trend and brand image origin, emotional value had a negative effect on global brand preference. In contrast, among Korean consumers, perceived value had a positive (+) effect on global brand preference in the order of functional value of quality, the functional value of price, and the social value. However, emotional value had no effect on global brand preference. Second, for both Korean and Vietnamese consumers, perceived value had a significant positive effect on purchase intention. Third, unlike the Korean consumer, for the Vietnamese consumer, global brand preference had a significant effect on purchase intention. Conclusions - The study implies the following. First, the Vietnamese bakery market has a high proportion of middle-aged customers in their 40s (64%). In terms of monthly income, there was a large proportion (40%) of high-income earners (over $325). Therefore, bakery consumption can be seen as concentrated among middle-aged and high-income consumers. Based on this, bakery strategies should include efforts to increase purchase prices as well as ways to attract local consumers (large cities). Second, unlike Korean consumers, among Vietnamese consumers, the resistance to a global brand based on emotional value (the ethnocentric tendency and brand image origin) can be seen as relatively low. Thus, in the case of the Vietnam bakery market, to increase a global brand's preference, the company should develop a differentiated strategy so that Vietnamese consumers can recognize it better, focusing on product quality, good service quality, and price in the local environment and on social value for social development. Third, in the case of the Vietnamese customer, we found that social value exerts the greatest influence on purchase intention. Therefore, a brand that engenders an image of building the local Vietnamese community can achieve a higher social value and influence purchase intention. In addition, although Vietnamese consumers have ethnocentric tendencies in terms of products, we found that if it is a preferred global brand then there are intentions to purchase. Fourth, in the case of Vietnam, if the preference for global brands is formed, consumer awareness may be connected to purchase intention. Therefore, global brands operating in Vietnam should pay attention to how to improve consumer preferences for global brands in order to increase purchase intention.

• Journal of Life Science
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• v.28 no.8
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• pp.931-937
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• 2018

Triptolide is a compound found in Tripterygium wilfordii and reported to have an anti-inflammatory and anti-oxidant activities. A previous study shows that the dietary supplementation with triptolide increases resistance to environmental stressors, including oxidative stress, heat shock, and ultraviolet irradiation, and extends lifespan in C. elegans. Here, we investigated the underlying mechanisms involved in the lifespan-extending effect of triptolide. The effect of triptolide on age-related diseases, such as diabetes mellitus and Alzheimer's disease, was also examined using animal disease models. The longevity phenotype conferred by triptolide was not observed in the eat-2 mutant, a well-known genetic model of dietary restriction, while there was an additional lifespan extension with triptolide in age-1 and clk-1 mutants. The long lifespan of age-1 mutant is resulted from a reduced insulin/IGF-1-like signaling and the clk-1 mutant lives longer than wild-type due to dysfunction of mitochondrial electron transport chain reaction. The effect of dietary restriction using bacterial dilution on lifespan also overlapped with that of triptolide. The toxicity of high glucose diet or transgenic human amyloid beta gene was significantly suppressed by the supplementation with triptolide. These findings suggest that triptolide can mimic the effect of dietary restriction on lifespan and onset of age-related diseases. We conclude that triptolide can be a strong candidate for the development of dietary restriction mimetics.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.6
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• pp.1367-1375
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• 2015

The purpose of this paper is to suggest 10 mm aggregate specification for thin layer asphalt pavement using steel slag. Aggregate gradations of conventional dense-graded asphalt mixtures were made by fuller's model, whereas 10 mm dense-graded asphalt mixture was obtained tender mix due to close to the maximum density line. The proposed aggregate gradation specification was made to have enough VMA and well-interlocking refer to foreign standards. The correlation between the proposed aggregate gradation and the properties of mixtures were analyzed using Gradation Ratio (GR) and Compacted Aggregate Density (CAD). The CAD index has a high $R^2$ of 0.86-0.99 because the CAD index is able to reflect various aggregate properties. As the results of evaluation by CAD index the proposed aggregate gradation provides more reliable stability and VMA. The percent passing (%) of aggregate size smaller than 0.3 mm was limited 10% or more for improving crack resistance. This limitation increased for 15% of the asphalt mixture's toughness.