• Title/Summary/Keyword: Resistance evaluation

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Study of Seismic Resistance Performance Evaluation Method for Existing Mid-Low Story RC Structure Buildings by Applying Fuzzy Theory (퍼지이론을 적용한 기존 중저층 철근콘크리트 건축물의 내진성능평가기법 연구)

  • Kim, Dong-Hee;Kim, Hyun-Su
    • Journal of Korean Association for Spatial Structures
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    • v.17 no.2
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    • pp.53-62
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    • 2017
  • This study aims to establish a seismic resistance performance evaluation method that makes sure to secure the seismic resistance performance of the existing mid-low story reinforced concrete structures. This study focuses on the development of the seismic resistance performance evaluation method for the overall seismic resistance performance evaluation on the buildings by applying fuzzy theory. This seismic resistance performance evaluation method considers the mutual relations among the type of force, the type of member, the type of story, and the states of deterioration of the buildings. The total seismic resistance performance index from this method was calculated by the intensity weight of each evaluation item, fuzzy measure, fuzzy integration. Moreover, the evaluation methodology was established in this study to identify the performance level of the Immediate Occupancy, Life Safe, Collapse Prevention by applying the fuzzy theory.

EVALUATION OF PROLIFERATION RESISTANCE USING THE INPRO METHODOLOGY

  • Yang, Myung-Seung;Park, Joo-Hwan;Ko, Won-Il;Song, Kee-Chan;Choi, Kun-Mo;Kim, Jin-Kyoung
    • Nuclear Engineering and Technology
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    • v.39 no.2
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    • pp.149-160
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    • 2007
  • The IAEA launched the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) and developed the INPRO Methodology to provide guidelines and to assess the characteristics of a future innovative nuclear energy system in areas such as safety, economics, waste management, and proliferation resistance. The proliferation resistance area of the INPRO Methodology is reviewed here, and modifications for further improvements are proposed. The evaluation metrics including the evaluation parameters, evaluation scales and acceptance limits are developed for a practical application of the methodology to assess the proliferation resistance. The proliferation resistant characteristics of the DUPIC fuel cycle are assessed by applying the modified INPRO Methodology based on the developed evaluation metrics and acceptance criteria. The evaluation procedure and the metrics can be utilized as a reference for an evaluation of the proliferation resistance of a future innovative nuclear energy system.

Reliability analysis and evaluation of LRFD resistance factors for CPT-based design of driven piles

  • Lee, Junhwan;Kim, Minki;Lee, Seung-Hwan
    • Geomechanics and Engineering
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    • v.1 no.1
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    • pp.17-34
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    • 2009
  • There has been growing agreement that geotechnical reliability-based design (RBD) is necessary for establishing more advanced and integrated design system. In this study, resistance factors for LRFD pile design using CPT results were investigated for axially loaded driven piles. In order to address variability in design methodology, different CPT-based methods and load-settlement criteria, popular in practice, were selected and used for evaluation of resistance factors. A total of 32 data sets from 13 test sites were collected from the literature. In order to maintain the statistical consistency of the data sets, the characteristic pile load capacity was introduced in reliability analysis and evaluation of resistance factors. It was found that values of resistance factors considerably differ for different design methods, load-settlement criteria, and load capacity components. For the total resistance, resistance factors for LCPC method were higher than others, while those for Aoki-Velloso's and Philipponnat's methods were in similar ranges. In respect to load-settlement criteria, 0.1B and Chin's criteria produced higher resistance factors than DeBeer's and Davisson's criteria. Resistance factors for the base and shaft resistances were also presented and analyzed.

A Study on Field Applicability Evaluation of the Hydrophobic - Low Viscosity Surface Treatment Material for Pavement Preventive Maintenance (소수성 특성을 이용한 저점도 AP 표면처리재의 현장 적용성 연구)

  • Choi, Jun Seong
    • International Journal of Highway Engineering
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    • v.16 no.1
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    • pp.31-39
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    • 2014
  • PURPOSES : Surface treatment material for pavement preventive maintenance should be inspected field applicability. This study(Part II) aimed to checkup coating characteristics and performance analysis using lab and field tests. The hydrophobic - low viscosity filling material for pavement preventive maintenance is presented in Part I, which is a series of companion study. METHODS : Relative comparison between general asphalt mixtures and surface treatment asphalt mixtures are analyzed and measured for the field application such as indirect tensile strength ratio(TSR), abrasion resistance, crack propagation resistance, temperature resistance, coating thickness, permeability resistance and skid resistance in terms of british pendulum number(BPN). RESULTS : It is found that TSR, crack propagation resistance and permeability resistance is increased as against uncoated asphalt specimen. Abrasion resistance and temperature resistance is secured from the initial coating thickness point of view, which is about 0.2~0.3mm. Skid resistance on the surface treatment pavement is satisfied with the BPN criteria of national highway because of exposed aggregate and crack sill induced pavement deterioration and damage cracks. CONCLUSIONS : The hydrophobic - low viscosity surface treatment material for pavement preventive maintenance is validated on field applicability evaluation based on quantitative analysis of coating thickness and performance analysis using lab and field tests.

A Study on the Thermal resistance Performance Evaluation Method of Building Exterior System for Passive House Construction (패시브하우스 구축을 위한 건물외피시스템 단열성능 평가 기법 개발에 관한 연구)

  • Kim, Young-Bong;Moon, Jae-Sik;Park, Dong-Cheon
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2017.11a
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    • pp.143-144
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    • 2017
  • Due to the recent depletion of natural resources and global warming, a passive house type building exterior system has been developed and applied. For this purpose, we developed a building exterior thermal resistance performance evaluation system and verify the feasibility of this system for evaluation of passive house building system.

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20(S)-ginsenoside Rh2 ameliorates ATRA resistance in APL by modulating lactylation-driven METTL3

  • Siyu Cheng;Langqun Chen;Jiahui Ying;Ying Wang;Wenjuan Jiang;Qi Zhang;Hong Zhang;Jiahe Wang;Chen Wang;Huimin Wu;Jing Ye;Liang Zhang
    • Journal of Ginseng Research
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    • v.48 no.3
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    • pp.298-309
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    • 2024
  • Background: 20(S)-ginsenoside Rh2(GRh2), an effective natural histone deacetylase inhibitor, can inhibit acute myeloid leukemia (AML) cell proliferation. Lactate regulated histone lactylation, which has different temporal dynamics from acetylation. However, whether the high level of lactylation modification that we first detected in acute promyelocytic leukemia (APL) is associated with all-trans retinoic acid (ATRA) resistance has not been reported. Furthermore, Whether GRh2 can regulate lactylation modification in ATRA-resistant APL remains unknown. Methods: Lactylation and METTL3 expression levels in ATRA-sensitive and ATRA-resistant APL cells were detected by Western blot analysis, qRT-PCR and CO-IP. Flow cytometry (FCM) and APL xenograft mouse models were used to determine the effect of METTL3 and GRh2 on ATRA-resistance. Results: Histone lactylation and METTL3 expression levels were considerably upregulated in ATRA-resistant APL cells. METTL3 was regulated by histone lactylation and direct lactylation modification. Overexpression of METTL3 promoted ATRA-resistance. GRh2 ameliorated ATRA-resistance by downregulated lactylation level and directly inhibiting METTL3. Conclusions: This study suggests that lactylation-modified METTL3 could provide a promising strategy for ameliorating ATRA-resistance in APL, and GRh2 could act as a potential lactylation-modified METTL3 inhibitor to ameliorate ATRA-resistance in APL.

Evaluation of Impact Resistance Performance of High Strength Concrete by Projectile Size and Compressive Strength (압축강도 및 비상체의 크기에 따른 고강도 콘크리트의 내충격 성능평가)

  • Kim, Hong-Sub;Kim, Gyu-Yong;Miyauchi, Hiroyukui;Nam, Jeong-Soo;Jeon, Young-Seok;Koo, Kyoung-Mo
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2011.05a
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    • pp.7-10
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    • 2011
  • In this study, evaluation system of impact resistance performance is proposed. Compressive strength of concrete is 40, 60 and 80MPa. It evaluate impact resistance performance to use projectile 6, 7 and 8mm size. As a result, safety performance is more higher when the compressive strength is increased in. Compared with Hughes's formula, evaluation system of impact resistance performance is appropriated.

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A Comparative Study on Skid Resistance Performance Evaluation Methods for Maintenance of Skid Resistance Pavement (미끄럼방지포장 유지관리를 위한 미끄럼저항 성능평가방법 비교 연구)

  • Hyun-Woo Cho;Sang-Kyun Noh;Bong-Chun Lee;Yoon-Seok Chung
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.27 no.6
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    • pp.79-85
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    • 2023
  • Skid resistance pavement is an accessory to the road and is a facility for the safe driving of cars by increasing the skid resistance of road pavement. In particular, in bad weather conditions such as snow, rain, and black ice, the skid resistance performance of skid resistance pavement greatly affects the safety of road traffic and drivers. However, BPT(British Pendulum Tester) has a test area of only 0.009 m2, making it difficult to represent the overall packaging surface. A reliable method of evaluating slip resistance performance is needed for maintaining non-slip packaging. In this study, the conventional BPT test and the skid resistance performance evaluation method of the PFT(Pavement Friction Tester) and µGT(Micro Grip Tester) tests were compared through guidelines and standard investigations and applied to the field skid resistance performance evaluation. In addition, skid resistance pavement with different skid resistance performance was installed at the test-bed and actual road demonstration sites to compare BPN(British Pendulum Number), SN(Skid Number), GN(Grip Number), and to derive correlations for each performance evaluation method. As a result of the experiment, SN and GN showed similar skid resistance performance, and the GN value was derived similar to BPN × 0.01.

A Study on the Performance Evaluation of Waterproof Sealant Materials for the Exterior Wall of PC Apartment House (PC 공동주택 외벽용 방수 실란트 자재의 성능 평가 연구)

  • Ko, Hyo-Jin;Kim, Yong-Ro
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2023.11a
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    • pp.221-222
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    • 2023
  • In this study, the performance evaluation of waterproof sealant materials applied to the outer wall of PC apartment houses was conducted. The sealant for PC members must have resistance to movement, and since it is exposed to outside air, weather resistance and water resistance are required.

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Antimicrobial Resistance Profile of Acinetobacter spp. Isolates from Retail Meat Samples under Campylobacter-Selective Conditions

  • Cha, Min-Hyeok;Kim, Sun Hee;Kim, Seokhwan;Lee, Woojung;Kwak, Hyo-Sun;Chi, Young-Min;Woo, Gun-Jo
    • Journal of Microbiology and Biotechnology
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    • v.31 no.5
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    • pp.733-739
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    • 2021
  • Acinetobacter strains are widely present in the environment. Some antimicrobial-resistant strains of this genus have been implicated in infections acquired in hospitals. Genetic similarities have been reported between Acinetobacter strains in nosocomial infections and those isolated from foods. However, the antimicrobial resistance of Acinetobacter strains in foods, such as meat, remains unclear. This study initially aimed to isolate Campylobacter strains; instead, strains of the genus Acinetobacter were isolated from meat products, and their antimicrobial resistance was investigated. In total, 58 Acinetobacter strains were isolated from 381 meat samples. Of these, 32 strains (38.6%) were from beef, 22 (26.5%) from pork, and 4 (4.8%) from duck meat. Antimicrobial susceptibility tests revealed that 12 strains were resistant to more than one antimicrobial agent, whereas two strains were multidrug-resistant; both strains were resistant to colistin. Cephalosporin antimicrobials showed high minimal inhibitory concentration against Acinetobacter strains. Resfinder analysis showed that one colistin-resistant strain carried mcr-4.3; this plasmid type was not confirmed, even when analyzed with PlasmidFinder. Analysis of the contig harboring mcr-4.3 using BLAST confirmed that this contig was related to mcr-4.3 of Acinetobacter baumannii. The increase in antimicrobial resistance in food production environments increases the resistance rate of Acinetobacter strains present in meat, inhibits the isolation of Campylobacter strains, and acts as a medium for the transmission of antimicrobial resistance in the environment. Therefore, further investigations are warranted to prevent the spread of antimicrobial resistance in food products.