• Journal of the Korean housing association
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• v.26 no.6
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• pp.35-42
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• 2015

The Brazilian Federal Housing Program "Minha Casa Minha Vida" -PMCMV (My House My Life) is part of a large housing policy to eradicate the housing deficit, estimated at around five million homes in the country. The Ministry for Cities created a network of independent research organizations to evaluate the program, and the PMCMV has attracted many studies. Despite the inherent worth of these individual studies, there is a need for a holistic evaluation. A Systematic Literature Review (SLR) is seen as an important contribution to focus research efforts on the problems identified, to avoid the repetition of studies and to provide novel insights. This article carried out a SLR to map and quantify the types of research and represent a graphic panorama of published studies. Gap spotting was part of the study. In the five-year period from 2010-2014, the SLR identified 1489 bibliographic items. The panorama is categorised according to types of publications, and the analysis of items shows that most studies are concentrated on housing policies, financial questions, urban impacts and Brazilian social development. The results of this SLR raise some new research questions and show opportunities to reduce errors in the housing projects themselves.

• Journal of East-West Nursing Research
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• v.26 no.1
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• pp.28-38
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• 2020

Purpose: The aim of this study was to provide information on the extent and variations of elderly residents' nursing care needs, and provision of nursing care across long term care facilities. Methods: A nationwide survey was conducted on nurse managers from 1,041 long term care facilities, by e-mail or fax, from August 16 to September 30 in 2017. A self-reported questionnaire consisting of 5 domains was used to collect data. Results: Facilities with more than 30 residents were more likely to need skilled nursing services and to obtain the nursing staff such as a registered nurse and a nurse's aide. Awareness and satisfaction of hospital-based home nursing care was high in all facilities. In addition, there are some differences in nurse managers' perceptions of the level of healthcare resources and required action by facility size. Nurse managers of senior congregate housings were more likely to have considerable difficulty in dealing with healthcare needs of residents and recognizing the healthcare resource shortage. A majority of nurse managers agreed on the need to employ a registered nurse. Conclusion: This study confirmed that it is essential to increase nurse staffing level and to reform the long term care insurance for enhancing the accessibility of healthcare services, especially for the residents in small long term care facilities. There is also a need to provide diverse education and training opportunities for nursing staff working in long term care facilities.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.7
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• pp.4033-4039
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• 2013

Links between cancer and metabolism have been suggested for a long time but compelling evidence for this hypothesis came from the recent molecular characterization of the LKB1/AMPK signaling pathway as a tumor suppressor axis. Besides the discovery of somatic mutations in the LKB1 gene in certain type of cancers, a critical emerging point was that the LKB1/AMPK axis remains generally functional and could be stimulated by pharmacological molecules such as metformin in cancer cells. In addition, AMPK plays a central role in the control of cell growth, proliferation and autophagy through the regulation of mTOR activity, which is consistently deregulated in cancer cells. Targeting of AMPK/mTOR is thus an attractive strategy in the development of therapeutic agents against non-small-cell lung cancer (NSCLC). In this review, the LKB1/AMPK/mTOR signaling pathway is described, highlighting its protective role, and opportunities for therapeutic intervention, and clinical trials in NSCLC.

• Journal of Microbiology and Biotechnology
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• v.22 no.1
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• pp.34-45
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• 2012

A thermophilic Bacillus stearothermophilus F1 produces an extremely thermostable serine protease. The F1 protease sequence was used to predict its three-dimensional (3D) structure to provide better insights into the relationship between the protein structure and biological function and to identify opportunities for protein engineering. The final model was evaluated to ensure its accuracy using three independent methods: Procheck, Verify3D, and Errat. The predicted 3D structure of F1 protease was compared with the crystal structure of serine proteases from mesophilic bacteria and archaea, and led to the identification of features that were related to protein stabilization. Higher thermostability correlated with an increased number of residues that were involved in ion pairs or networks of ion pairs. Therefore, the mutants W200R and D58S were designed using site-directed mutagenesis to investigate F1 protease stability. The effects of addition and disruption of ion pair networks on the activity and various stabilities of mutant F1 proteases were compared with those of the wild-type F1 protease.

• Plant Biotechnology Reports
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• v.4 no.4
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• pp.293-301
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• 2010

The feasibility of two strategies for transgene pyramiding using Agrobacterium-mediated transformation was investigated to develop a transgenic potato (Solanum tuberosum L. cv. Iwa) with resistance to potato tuber moth (PTM) (Phthorimaea operculella (Zeller)). In the first approach, cry1Ac9 and cry9Aa2 genes were introduced simultaneously using a kanamycin (nptII) selectable marker gene. The second approach involved the sequential introduction (re-transformation) of a cry1Ac9 gene, using a hygromycin resistance (hpt) selectable marker gene, into an existing line transgenic for a cry9Aa2 gene and a kanamycin resistance (nptII) selectable marker gene. Multiplex polymerase chain reaction (PCR) confirmed the presence of the specific selectable marker gene and both cry genes in all regenerated lines. The relative steady-state level of the cry gene transcripts in leaves was quantified in all regenerated lines by real-time PCR analysis. Re-transformation proved to be a flexible approach to effectively pyramid genes for PTM resistance in potato, since it allowed the second gene to be added to a line that was previously identified as having a high level of resistance. Larval growth of PTM was significantly inhibited on excised greenhouse-grown leaves in all transgenic lines, although no lines expressing both cry genes exhibited any greater resistance to PTM larvae over that previously observed for the individual genes. It is anticipated that these lines will permit more durable resistance by delaying the opportunities for PTM adaptation to the individual cry genes.

• Polymer(Korea)
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• v.37 no.4
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• pp.411-419
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• 2013

Various biomaterials have been widely used for biomedical applications, including bio-organs, medical devices, and clinical devices like vessel, blood pumps, artificial kidneys and hearts, even in contact with blood. The issue of blood compatibility has been studied intensively to prevent negative effects such as thrombosis due to the implanted devices. The use of lotus-leaf-like structured surfaces has been extended to an increasing number of applications such as contamination prevention and anticorrosion applications. Various methods such as template, sol-gel transition, layer-by-layer, and other methods, developed for the fabrication of lotus-leaf-like surfaces have been reported for major industrial applications. Recently, the non-wettable character of these surfaces has been shown to be useful for biomedical applications ranging from blood-vessel replacement to antibacterial surface treatment. In this review, we provide a summary of current and future research efforts and opportunities in the development and medical applications of lotus-leaf-like structure surfaces.

• Journal of Astronomy and Space Sciences
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• v.30 no.4
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• pp.255-267
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• 2013

In this research, the ground contact opportunity for the fictitious low lunar orbiter is analyzed to prepare for a future Korean lunar orbiter mission. The ground contact opportunity is basically derived from geometrical relations between the typical ground stations at the Earth, the relative positions of the Earth and Moon, and finally, the lunar orbiter itself. Both the cut-off angle and the orbiter's Line of Sight (LOS) conditions (weather orbiter is located at near or far side of the Moon seen from the Earth) are considered to determine the ground contact opportunities. Four KOMPSAT Ground Stations (KGSs) are assumed to be Korea's future Near Earth Networks (NENs) to support lunar missions, and world-wide separated Deep Space Networks (DSNs) are also included during the contact availability analysis. As a result, it is concluded that about 138 times of contact will be made between the orbiter and the Daejeon station during 27.3 days of prediction time span. If these contact times are converted into contact duration, the duration is found to be about 8.55 days, about 31.31% of 27.3 days. It is discovered that selected four KGSs cannot provide continuous tracking of the lunar orbiter, meaning that international collaboration is necessary to track Korea's future lunar orbiter effectively. Possible combinations of world-wide separated DSNs are also suggested to compensate for the lack of contact availability with only four KGSs, as with primary and backup station concepts. The provided algorithm can be easily modified to support any type of orbit around the Moon, and therefore, the presented results could aid further progress in the design field of Korea's lunar orbiter missions.

• Journal of Gifted/Talented Education
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• v.23 no.6
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• pp.1117-1145
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• 2013

Research on entrepreneurial giftedness is in its initial stage and the importance is increasing these days. The purpose of this article is to establish a foundation of entrepreneurial giftedness research by conceptualizing the concept and characteristics of entrepreneurial giftedness. The author reviewed prior research on entrepreneur and entrepreneurship, potential entrepreneur, gifted youth in invention, and entrepreneurial gifted youth, and proposed a new perspective on entrepreneurial gifted youth based on the findings from the review. Entrepreneurial giftedness proposed in this study is someone who is risk-taking to achieve opportunities and innovation and who has potential to be competent in managing resources. The author also proposed that entrepreneurial giftedness study needs to focus on developmental characteristics, management ability, and practical intelligence. Finally, based on the findings from previous research on entrepreneurial giftedness, environmental and personality characteristics, temperament and character, cognitive traits, and vocational interest of entrepreneurial giftedness are discussed. Implications and further research directions were discussed.

• STI Policy Review
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• v.9 no.1
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• pp.99-132
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• 2018

Developing countries face numerous challenges in the process of building science, technology, and research capacity; in particular, the formation and accumulation of skilled S&T workforce. The lack of organized and sustainable higher education options (Master and Doctoral programs), nonexistent or low-quality academic programs, and the absence of research-oriented study options are some of the strong contributors for talented students to emigrate to developed countries. At the same time, the consolidation of a global knowledge economy, the internationalization of higher education, and the competition to attract foreign talent in industrialized countries present challenges for underdeveloped nations to retain their already scarce skilled human resources. In this context, student mobility has been used as a policy mechanism to cope with S&T workforce shortages in S&T laggard nations. It has also enabled opportunities for international cooperation to play a key role. While significant literature has been devoted to studying the gains of developed nations with the arrival and potential migration of the mobilized students, few scholarly inquiries have addressed the benefits and losses experienced by their countries of origin. More importantly, limited research can be found on policy options and policy implications for developing countries to deal with the dilemmas presented by the brain-drain/brain-circulation debate. The goal of this article is to study empirical evidence of an international cooperation initiative for student mobility between the Republic of Korea and Guatemala (implemented during 2009-2015). The paper analyzes this particular international cooperation experience from the perspective of the different actors involved and attempts to draw policy implications and policy options for developing countries to deal with potential risks and gains derived from international mobility for their S&T capacity building.

• The Korean Journal of Franchise Management
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• v.11 no.3
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• pp.19-26
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• 2020

Purpose: The old axion to put the customers first (e.g., customers are king, customers are always right) has been taken for granted in the service sector. In addition, many companies in South Korea are providing customer-first education for employees at their contact points to strengthen their competitiveness. However, excessive increase in the psychological power of the customer can lead to a problem of abuse of power, called 'Gap-jil.' Despite these concerns, most companies hardly discard policies to give high priority to customers because of the assumption that it enhances customer satisfaction leading to organizational performance. However, in recent years, some franchise catering companies have posted warnings about the abuse of power by customers, and a movement to pursue a power-balancing between service providers and their customers is spreading. Research design, data, and methodology: This research is conducted to reconsider the principle of the customer-first perspective and to create a basis for arguments that can solve the problem of abuse of power, which is recognized as a serious social problem. In this research, we test and analyze the effect of customers' psychological power in the context of a restaurant on expectation for service and response to service failure. Result: The result of an experimental study shows that the effect of psychological power on customer satisfaction can be somewhat negative. Also, customers with high psychological power are more likely to have high service expectations. Especially high psychological power of customers causes a difference in the expectation level of human factors such as employee attitude, while the difference in expectations of non-human factors such as restaurant atmosphere was not statistically significant. In addition, when customers with high psychological power encounter service failure situation, they are more likely to feel disappointment and regret with a service provider. Meanwhile, the effect of psychological power on complaining behaviors are not significant. Conclusions: The findings of this research provide meaningful implications that the service providers should reconsider their existing corporate culture and management policies that put customers first. In addition, the result of this research is provided meaningful opportunities to review the management philosophy for the company's customers and the education philosophy for the employee education.