• 제목/요약/키워드: Research laboratory

검색결과 16,299건 처리시간 0.047초

The effect of G009 on lipidperoxidation in rat liver microsome

  • Lee, June-Woo;Jeong, Hoon;Han, Man-Deuk;Kim, Su-Ung;Lee, Seung-Yong;Kim, Kee-Nam;Chung, Sung-Kyun;Baek, Seong-Jin;Song, Jae-Jin;Kim, Yong-Seok;Kang, Sang-Mo
    • 한국응용약물학회:학술대회논문집
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    • 한국응용약물학회 1995년도 춘계학술대회
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    • pp.107-107
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    • 1995
  • The purpose of this study was to observe the effects of the polysaccharide(G009) obtained from liquid cultured Ganoderma lucidum IY009 on the lipidperoxidation in rat liver microsome. It is well known that the polysaccharide of G. lucidum have the hepatoprotective activity, antitumor activity etc., which was thought to have the relationship to anti-lipidperoxidation. In order to the estimate the effects of anti-lipidperoxidation of the polysaccharide obtained from G. lucidum IY009, enzymatic and nonenzymatic reaction were performed, in vitro, in rat liver microsome. In enzymatic lipid peroxidation reaction by ADP/FeCl$_3$/NADPH and $CCl_4$/NADPH, G009(1mg/ml) inhibited 77.4%, 39.4%, respectively, and the nonenzymatic reaction strongly exhibited 97.4% inhibition. And also, in enzymatic and nonenzymatic inducers treated with G009, the formation of MDA was progressively greater decreased by raising G009 concentration. These results suggest that anti-lipidperoxidation by G009 treatment may be play an important part in liver protection action.

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Spatiotemporal behavior of excited Xe atoms density in Counter discharged type AC-PDP

  • Hong, Young-June;Oh, Phil-Yong;Jeong, Se-Hoon;Hong, Jong-Hwa;Kim, Jung-Hyun;Gyu, Yong;Cho, Seok-Ho;Hong, Sung-Hee;Hong, Byoung-Hee;Choi, Eun-Ha
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2007년도 7th International Meeting on Information Display 제7권1호
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    • pp.574-577
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    • 2007
  • We have measured the excited Xe atoms density in the $1s_5$ metastable states by laser absorption spectroscopy in counter discharged type AC-PDP. This experiment has shown the characteristic of the excited Xe atoms density which is relation to the visible light efficiency of PDP. The density of counter discharged AC-PDP have measured to be $9.47\;{\times}\;10^{13}\;cm{-3}$. The result has been shown to higher value than $1.45\;{\times}\;10^{13}\;cm^{-3}$ of conventional AC-PDP.

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곤충자원으로부터 항동맥경화 활성물질 탐색 (Screening of Anti-atherogenic Substances from Insect Resources)

  • 박두상;윤미애;서명철;유하나;김주령;정태숙;박호용
    • 생약학회지
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    • 제35권3호통권138호
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    • pp.233-238
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    • 2004
  • Lipoprotein-associated phospholipase $A_2\;(Lp-PLA_2)$ is a potential biomarker of coronary heart disease and plays an important proinflammatory role in the progression of atherosclerosis. Also acyl-CoA: cholesterol acyltransferase (ACAT) and oxidized low-density lipoprotein (LDL) playa key role in atherosclerosis, respectively. And so, the inhibitory activities of the methanol extracts of 42 insect resources were examined on $Lp-PLA_2$, ACAT, and LDL oxidation for screening of anti-atherogenic substances. Among them, the methanol extracts of Eurydema rugosa significantly inhibited all of upper three activities. Several kinds of tested insects having high inhibitory effect with the methanol extracts were extracted with n-hexane, ethyl acetate, and acetone, and their inhibitory activities were tested.

임상병리검사학의 학문분류체계 개발을 위한 연구 (A Study on the Development of Academic Classification System for Biomedical Laboratory Science)

  • 구본경
    • 대한임상검사과학회지
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    • 제49권4호
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    • pp.477-488
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    • 2017
  • 이 연구는 임상병리검사학(또는 임상검사과학, 의학검사과학, 의생명검사과학)에 대한 체계적 인 접근을 하기 위해 임상병리검사학의 정체성과 학문분류체계를 가지고 논의하였다. 임상병리검사학은 한국 연구재단의 학술연구분야분류에 등재되어 있지 않다. 국내에서는 1963년 임상병리검사학과 최초로 신설된 이후 전국에 임상병리검사학과가 52개에 이르고 있다. 학문적 정체성에도 불구하고 제도적으로 임상병리검사학은 전문적 영역을 확보하지 못하고 있는 실정이다. 학술연구분야분류를 보면 물리치료학, 작업치료학, 치위생학은 체계적으로 분류되어 그 학문성을 인정받고 있다. 이 연구는 임상병리검사학의 새로운 학문분류체계이다. 내용 연구는 다음과 같이 요약된다. 임상병리사의 학문은 대분류 의약학, 중분류 임상병리학, 소분류 임상병리검사학에 위치한다. 세분류의 학문용어는 "혈액수혈학, 면역생화학, 미생물기생충학, 유전분자생물학, 조직세포학, 심폐신경생리학"으로 구성한다.