• Archives of Pharmacal Research
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• v.18 no.3
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• pp.215-216
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• 1995

• ETRI Journal
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• v.42 no.1
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• pp.129-137
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• 2020

All-solid-state batteries are promising energy storage devices in which high-energy-density and superior safety can be obtained by efficient cell design and the use of nonflammable solid electrolytes, respectively. This paper presents a systematic study of experimental factors that affect the electrochemical performance of all-solid-state batteries. The morphological changes in composite electrodes fabricated using different mixing speeds are carefully observed, and the corresponding electrochemical performances are evaluated in symmetric cell and half-cell configurations. We also investigate the effect of the composite electrode thickness at different charge/discharge rates for the realization of all-solid-state batteries with high-energy-density. The results of this investigation confirm a consistent relationship between the cell capacity and the ionic resistance within the composite electrodes. Finally, a concentration-gradient composite electrode design is presented for enhanced power density in thick composite electrodes; it provides a promising route to improving the cell performance simply by composite electrode design.

• Journal of the Korean Society of Safety
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• v.34 no.4
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• pp.85-94
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• 2019

Through the survey on the current status of hazardous substances in laboratories, the research institute is designed to establish measures to improve the management of university laboratories and to create a safe laboratory. We intend to explore countermeasures by confirming and reviewing the recognition of the statutes in the "Guidelines for the Implementation of the Laboratory Pre-Hazard Factors Analysis" through the questionnaire. Although there are various parts to create a pleasant environment for a laboratory, the most important part is the role of a laboratory manager in the area where each and every one of the laboratory's directors is the "Act on the Establishment of a Safety Environment in a Laboratory", but if the laboratory is not to be accident-prone, the laboratory's responsibility is to be more secure. This research is intended to be funded by research to reasonably implement" Guidelines for the Implementation of the Laboratory Pre-Hazard Factors Analysis" before applying to universities and to protect field-based research activities and to reasonably reduce safety accident prevention and risk.

• Natural Product Sciences
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• v.14 no.3
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• pp.182-186
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• 2008

Scutellaria baicalensis Georgi (SBG) is traditionally used medicinal herb that has anti-oxidant, anticancer and anti-inflammatory effects. In this study, we investigated whether the extracts of SBG have the inhibitory activity in the osteoclast differentiation by using mouse monocytes RAW264.7 cells and primary mouse bone marrow-derived macrophages (BMMs). Methanol extract (ME) from SBG was successively fractionated into methylene chloride (MF), ethylacetate (EF) and n-butanol fraction (BF). The activity assay for tartrateresistant acid phosphatase (TRAP) and Western blot analysis were employed to evaluate the osteoclasts differentiation and the activation of mitogen-activated protein (MAP) kinases, respectively. ME, MF, EF and BF significantly and dose-dependently inhibited osteoclast differentiation without the decrease of cell viability at the concentrations used in this study. In addition, ME significantly inhibited the activation of c-jun-N-terminal kinase (JNK). In conclusion, this study firstly demonstrated that ME of SBG has the potential to inhibit the osteoclast differentiation through the suppression of JNK activation partially.

• Proceedings of the Ginseng society Conference
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• 2007.05a
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• pp.8-8
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• 2007

• Proceedings of The Korean Society of Agricultural and Forest Meteorology Conference
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• 2012.07a
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• pp.132-136
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• 2012

• Toxicological Research
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• v.24 no.3
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• pp.175-182
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• 2008

DNA-dependent protein kinase(DNA-PK) is involved in joining DNA double-strand breaks induced by ionizing radiation or V(D)J recombination and is activated by DNA ends and composed of a DNA binding subunit, Ku, and a catalytic subunit, DNA-PKcs. It has been suggested that DNA-PK might be $2^{nd}$ upstream kinase for protein kinase B(PKB). In this report, we showed that Ser473 phosphorylation in the hydrophobic-motif of PKB is blocked in DNA-PK knockout mouse embryonic fibroblast cells(MEFs) following insulin stimulation, while there is no effect on Ser473 phosphorylation in DNA-PK wild type MEF cells. The observation is further confirmed in human glioblastoma cells expressing a mutant form of DNA-PK(M059J) and a wild-type of DNA-PK(M059K), indicating that DNA-PK is indeed important for PKB activation. Furthermore, the treatment of cells with doxorubicin, DNA-damage inducing agent, leads to PKB phosphorylation on Ser473 in control MEF cells while there is no response in DNA-PK knockout MEF cells. Together, these results proposed that DNA-PK has a potential role in insulin signaling as well as DNA-repair signaling pathway.

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2005.04a
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• pp.75-75
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• 2005

• 한국초전도학회:학술대회논문집
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• 2007.07a
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• pp.70-70
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• 2007

• Proceedings of the Materials Research Society of Korea Conference
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• 1998.08a
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• pp.137.2-137
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• 1998