• Title/Summary/Keyword: Research laboratory

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The effect of G009 on lipidperoxidation in rat liver microsome

  • Lee, June-Woo;Jeong, Hoon;Han, Man-Deuk;Kim, Su-Ung;Lee, Seung-Yong;Kim, Kee-Nam;Chung, Sung-Kyun;Baek, Seong-Jin;Song, Jae-Jin;Kim, Yong-Seok;Kang, Sang-Mo
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1995.04a
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    • pp.107-107
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    • 1995
  • The purpose of this study was to observe the effects of the polysaccharide(G009) obtained from liquid cultured Ganoderma lucidum IY009 on the lipidperoxidation in rat liver microsome. It is well known that the polysaccharide of G. lucidum have the hepatoprotective activity, antitumor activity etc., which was thought to have the relationship to anti-lipidperoxidation. In order to the estimate the effects of anti-lipidperoxidation of the polysaccharide obtained from G. lucidum IY009, enzymatic and nonenzymatic reaction were performed, in vitro, in rat liver microsome. In enzymatic lipid peroxidation reaction by ADP/FeCl$_3$/NADPH and $CCl_4$/NADPH, G009(1mg/ml) inhibited 77.4%, 39.4%, respectively, and the nonenzymatic reaction strongly exhibited 97.4% inhibition. And also, in enzymatic and nonenzymatic inducers treated with G009, the formation of MDA was progressively greater decreased by raising G009 concentration. These results suggest that anti-lipidperoxidation by G009 treatment may be play an important part in liver protection action.

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Spatiotemporal behavior of excited Xe atoms density in Counter discharged type AC-PDP

  • Hong, Young-June;Oh, Phil-Yong;Jeong, Se-Hoon;Hong, Jong-Hwa;Kim, Jung-Hyun;Gyu, Yong;Cho, Seok-Ho;Hong, Sung-Hee;Hong, Byoung-Hee;Choi, Eun-Ha
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08a
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    • pp.574-577
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    • 2007
  • We have measured the excited Xe atoms density in the $1s_5$ metastable states by laser absorption spectroscopy in counter discharged type AC-PDP. This experiment has shown the characteristic of the excited Xe atoms density which is relation to the visible light efficiency of PDP. The density of counter discharged AC-PDP have measured to be $9.47\;{\times}\;10^{13}\;cm{-3}$. The result has been shown to higher value than $1.45\;{\times}\;10^{13}\;cm^{-3}$ of conventional AC-PDP.

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Screening of Anti-atherogenic Substances from Insect Resources (곤충자원으로부터 항동맥경화 활성물질 탐색)

  • Park, Doo-Sang;Yoon, Mi-Ae;Xu, Ming-Zhe;Yu, Ha-Na;Kim, Ju-Ryoung;Jeong, Tae-Sook;Park, Ho-Yong
    • Korean Journal of Pharmacognosy
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    • v.35 no.3 s.138
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    • pp.233-238
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    • 2004
  • Lipoprotein-associated phospholipase $A_2\;(Lp-PLA_2)$ is a potential biomarker of coronary heart disease and plays an important proinflammatory role in the progression of atherosclerosis. Also acyl-CoA: cholesterol acyltransferase (ACAT) and oxidized low-density lipoprotein (LDL) playa key role in atherosclerosis, respectively. And so, the inhibitory activities of the methanol extracts of 42 insect resources were examined on $Lp-PLA_2$, ACAT, and LDL oxidation for screening of anti-atherogenic substances. Among them, the methanol extracts of Eurydema rugosa significantly inhibited all of upper three activities. Several kinds of tested insects having high inhibitory effect with the methanol extracts were extracted with n-hexane, ethyl acetate, and acetone, and their inhibitory activities were tested.

A Study on the Development of Academic Classification System for Biomedical Laboratory Science (임상병리검사학의 학문분류체계 개발을 위한 연구)

  • Koo, Bon-Kyeong
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.4
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    • pp.477-488
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    • 2017
  • This study presents a discussion on the biomedical laboratory science (formally clinical laboratory science or medical laboratory science) with the identity of biomedical laboratory science, as well as the academic classification system for systematic approach. The field of biomedical laboratory science is not registered in the academic research area classification system of the National Research Foundation of Korea. Since the inception of the first department of biomedical laboratory science in 1963, about 52 departments were since established. Despite the scientific identity, biomedical laboratory science have not been acknowledged professionally in most institutions. Observing the academic research area classification, the physical therapy, occupational therapy, and dental hygiene science are systematically classified and approved the identities by the authorities. This study is freshly academic area classification system of the biomedical laboratory science. The contents of this study are summarized as follows. The medical laboratory technologist's discipline is considered within the medical and science category, clinical pathology in class, and biomedical laboratory science in division. Sections of biomedical laboratory science include hematology, transfusionology, immunology, biochemistry, microbiology, parasitology, science, molecular biology, histology, cytology, cardiopulmonary physiology, and neurophysiology.