• Journal of Digital Convergence
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• v.10 no.11
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• pp.579-588
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• 2012

Inclusion of hearing impaired students in general schools is the current tendency in deaf education today. The goal of inclusion is to promote the academic and social inclusion of hearing impaired students, where academic inclusion focuses on higher academic achievement and class participation level. However, some studies have shown that hearing impaired students attending general schools mostly experience feelings of isolation, rejection and loneliness, and encounter identity development problems. This study reviews the research on the inclusion of hearing impaired students in general schools, as well as the perceptions of their parents, teachers on their academic and social inclusion. A further aim of this study is to explore the supporting services, teachers's attitude, career guidance service and effective collaborative partnership among teachers for hearing impaired students. This study concludes with suggesting the community of knowledge as integrative supporting strategy for inclusion.

• Polymer(Korea)
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• v.30 no.6
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• pp.572-575
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• 2006

In this work, a variety of polymer based jelly phantoms suitable for the hyperthermia operations to human organs was synthesized in order to confirm the possibility of auxiliary cancer therapy. Specifically, using an appropriate material composition including polyethylene, Jelly phantoms for brain was prepared and characterized their electrical properties suitable for the monitoring the effect of electromagnetic wave from code division multiple access (CDMA) and personal communication service (PCS) on the human body. In the future, after injection of ferromagnetic nanoparticle into the jelly phantoms, new approach to propose the cancer therapy can be anticipated by monitoring the degree of temperature rise in human body using the photograph of Infrared camera.

• Animal cells and systems
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• v.4 no.3
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• pp.287-292
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• 2000

The present work examined the role of gonadotropin-releasing hormone (GnRH) and dopaminergic drugs on the secretion of maturational gonadotropin (GTH II) in relation to testosterone m treatment. This study provides evidence that the plasma GTH II levels are increased by T treatment in precocious males, but not in the immature animal. In addition, GnRH analogue (GnRHa) alone significantly increased the plasma GTH II secretion in immature rainbow trout treated with T, as well as in T-treated and T-untreated precocious males. However, injection with either dopamine (DA) or domperidone (DOM; DA D2 receptor antagonist) alone did not alter the basal plasma GTH 11 secretion in all experimental groups. The secretion of GTH II in the T-treated precocious males was remarkably influenced by GnRHa or combination of dopaminergic drugs. Notably, the effects of dopaminergic drugs on GnRHa-induced GTH II secretion w8s prolonged by T in precocious males. In T-treated immature animals, GnRHa-induced GTH II secretion was Increased only by a dose DOM (10$\mu$g/g body n) but not by higher dose DOM (100$\mu$/g body wt). In the T-untreated immature rainbow trout, however, plasma GTH 11 secretion was not influenced by the same treatments. Therefore, these results indicate that DA may be acting indirectly by blocking the effect of GnRH on GTH II secretion in vivo. T may act to modulate the relative contribution by the stimulatory (GnRH) and inhibitory (DA) neuroendocrine factors, which would ultimately determine the pattern of GTH II secretion.

• Journal of the Korea Society of Computer and Information
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• v.11 no.1 s.39
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• pp.185-194
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• 2006

The ubiquitous computing environment focuses on recognizing the context and Physical entities, whereas, previous computing environments mainly focused on the conversational interactions between the computer and the user. For this reason, there has been an increase in the research of context aware computing environments. In previous researches , context services are designed using context ontology used in context aware middleware. So, context service cannot change the context ontology in execution time. We propose a hierarchical context ontology management for context aware service to change their ontology in execution time. And we also a resolution model for context conflict which is occurred in inference of context. We have designed a middleware based on this model and implemented the middleware. As the middleware is implemented on the OSGi framework, it can cause interoperability among devices such as computers, PDAs, home appliances and sensors. It can also support the development and operation of context aware services, which are required in the ubiquitous computing environment.

• Animal cells and systems
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• v.16 no.2
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• pp.145-153
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• 2012

The pear psylla, $Cacopsylla$ $pyricola$ (Hemiptera: Psyllidae), is a serious insect pest of commercial pear crops. The species, which resides on pear trees throughout its life cycle, is rapidly spreading in some regions of the world. The population genetic structure of the species collected from several pear orchards in Korea was studied to understand the nature of dispersal and field ecology of the species. The 658-bp region of mitochondrial COI gene and the 716-bp long complete internal transcribed spacer 2 (ITS2) of the nuclear ribosomal DNA were sequenced. Unlike other previously studied insect pests, the COI-based genetic diversity of the pear psylla was extremely low (maximum sequence divergence of 0.15%). This finding allowed us to conclude that the species may have been introduced in Korea relatively recently. ITS2 sequence-based analyses of phylogeny, population differentiation, gene flow, and hierarchical population structure all concordantly suggested that the pear psylla populations in Korea are neither genetically isolated nor hampered for gene flow. These genetic data are concordant with the dispersal of an overwintering winterform morph outside the non-pear habitat in the fall.

• Journal of the Korea Society of Computer and Information
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• v.15 no.3
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• pp.1-10
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• 2010

As processor platforms are continuously moving toward wireless mobile systems, embedded mobile processors are expected to perform more and more powerful, and therefore the development of an efficient power management algorithm for these battery-operated mobile and handheld systems has become a critical challenge. It is well known that a memory system is a main performance limiter in the processor point of view. Although many DVFS studies have been considered for the efficient utilization of limited battery resources, recent works do not explicitly show the interaction between the processor and the memory. In this research, to properly reflect short/long-term memory access patterns of the embedded workloads in wireless mobile processors, we propose a memory buffer utilization as a new index of DVFS level prediction. The simulation results show that our solution provides 5.86% energy saving compared to the existing DVFS policy in case of memory intensive applications, and it provides 3.60% energy saving on average.

• Korean Journal of Veterinary Research
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• v.40 no.2
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• pp.229-236
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• 2000

The synthesis of steroid hormone starts from cholesterol. Steroidogenic acute regulatory protein (StAR) acutely transfers cholesterol from the outer mitochondrial membrane to the inner in the early step of steroidogenesis. Many kinds of steroid hormone are mainly synthesized in adrenal grand, ovary, and testis. Among the steroid hormone, testosterone is synthesized in Leydig cells of the testis, the production of testosterone significantly increases in adult testis after puberty onset. Therefore, we think that the expression of StAR mRNA in testis will change according to the testicular development. The aim of this study is to determine the distribution of StAR mRNA in immature and adult rat testes and to confirm the functions of StAR in these testes. Thus, in situ hybridization was used in rat testes of the 2, 4, and 10 weeks of age. StAR mRNA was expressed in Leydig cells. Positive signals of StAR mRNA were weakly detected in Leydig cells of the 2 weeks of age. But, StAR mRNA was strongly expressed in Leydig cells of the 4 and 10 weeks of age, where steroidogenesis actively occur. In our results, the pattern of StAR mRNA expression was similar to the pattern of testosterone production in immature and adult rat testes. In conclusion, we can suggest that StAR acts as an important factor to regulate the synthesis of testosterone in Leydig cells of the rat testis.

• Journal of the Korean Wood Science and Technology
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• v.27 no.3
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• pp.31-38
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• 1999

This paper deals with a coating technique of hardening surface layer of softwood{Larix leptolepis) flooring board to improve its surface properties such as hardness and abrasion resisitance without spoiling its exellent qualities such as beautiful color tones and great strength. For surface hardening of the wood, polyurethane wood sealer was used as under coat, polyurethane sanding sealer as intermediate coat, and UV-curing epoxy acrylate and urethane acrylate varnishes as top coat. The hardness of the wood was improved by the coating treatment and it was similar to that of high density hardwood such as oak, keruing. The abrasion resistance of the coated wood was greatly improved by UV curing epoxy acrylate or urethane acrylate varnishes. Adhesion properties and impact resisitance of the coated wood surface were also good. It was suggested that the well-coated larch wood could be used as interior flooring board as substitute for hardwood such as keruing.

• Journal of Life Science
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• v.17 no.1 s.81
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• pp.18-23
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• 2007

Fe65, a neuron-specific adaptor protein, has two phosphotyrosine binding (PTB) domains. The second PTB (PTB2) domain interacts with intracellular domain fragment (AICD) of amyloid beta precursor protein (APP). Recent studies suggested that tile complex is composed of AICD and Fe65 transactivates genes that are responsible for neuronal cell death in Alzheimer's disease (AD). Therefore, a compound inhibiting the interaction between Fe65 and AICD can be a drug candidate to treat AD. However, it remains unclear how Fe65 recognizes AICD at a molecular level. Here, we report high-level production of the PTB2 domain of Fe65 in the baculovirus system. We found that the baculovirus system is an efficient method to obtain the Fe65 PTB2 domain, compared with the bacterial and mammalian expression systems. The purified recombinant protein was used for crystallization to determine its crystal structure helping to understand the molecular mechanism of Fe65-dependent signaling and to design its inhibitors.

• Journal of Genetic Medicine
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• v.12 no.1
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• pp.57-60
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• 2015

CHARGE syndrome (coloboma, heart defects, atresia choanae, retarded growth and development, genital hypoplasia, and ear abnormalities) is characterized by multiple malformations and is diagnosed using distinct consensus criteria. Mutations in the gene encoding chromodomain helicase DNA-binding protein 7 (CHD7) are the major cause of CHARGE syndrome. Clinical features of CHARGE syndrome considerably overlap those of 22q11.2 deletion syndrome. Of these features, immunodeficiency and hypocalcemia are frequently reported in patients with 22q11.2 deletion syndrome but are rarely reported in patients with CHARGE syndrome. In this report, we have described the case of a patient with typical phenotypes of 22q11.2 deletion syndrome but without the proven chromosome microdeletion. Mutation analysis of CHD7 identified a pathogenic mutation (c.2238+1G>A) in this patient. To our knowledge, this is the first case of CHARGE syndrome with immunodeficiency and hypocalcemia in Korea. Our observations suggest that mutation analysis of CHD7 should be performed for patients showing the typical phenotypes of 22q11.2 deletion syndrome but lacking the proven chromosome microdeletion.