• Title/Summary/Keyword: Research Process Engineering

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Rapid and Accurate Detection of Bacillus anthracis Spores Using Peptide-Quantum Dot Conjugates

  • Park, Tae-Jung;Park, Jong-Pil;Seo, Gwi-Moon;Chai, Young-Gyu;Lee, Sang-Yup
    • Journal of Microbiology and Biotechnology
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    • v.16 no.11
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    • pp.1713-1719
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    • 2006
  • A method for the simple, rapid, specific, and accurate detection of Bacillus anthracis spores was developed by employing specific capture peptides conjugated with fluorescent quantum dots (QDs). It was possible to distinguish B. anthracis spores from the spores of B. thuringiensis and B. cereus using these peptide-QD conjugates by flow cytometric and confocal laser scanning microscopic analyses. For more convenient high-throughput detection of B. anthracis spores, spectrofluorometric analysis of spore-peptide-QD conjugates was performed. B. anthracis spores could be detected in less than 1 h using this method. In order to avoid any minor yet false-positive signal caused by the presence of B. thuringiensis spores, the B-Negative peptide, which can only bind to B. thuringiensis, conjugated with another type of QD that fluoresces at different wavelength was also developed. In the presence of mixed B. anthracis and B. thuringiensis spores, the BABA peptide conjugated with QD525 and the B-Negative peptide conjugated with QD585 were able to bind to the former and the latter, specifically and respectively, thus allowing the clear detection of B. anthracis spores against B. thuringiensis spores by using two QD-labeling systems. This capture peptide-conjugated QD system should be useful for the detection of B. anthracis spores.

In-line Automatic defect repair method for TFT-LCD Production

  • Arai, Takeshi;Nakasu, N.;Yoshimura, K.;Edamura, T.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2009.10a
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    • pp.1036-1039
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    • 2009
  • We have developed an automated circuit defect repair method. We focused on the resist patterns on the circuit material layer of TFT substrates before the etching process. In this paper, we report on the repair method that utilizes the syringe system and the stability of the open defect repair process.

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Fabrication of Graphite-Ni Composite Powders and Effect of Thermal Spray Coating Parameters on Mechanical and Microstructural Properties (Graphite-Ni계 분말의 제조 및 용사 코팅 특성에 미치는 공정변수의 영향)

  • Kwon Joon-Chul;Cho Mun-Kwan;Kim Il-Ho;Hong Tae-Whan;Kweon Soon-Yong;Lee Young-Geun;Park Soon-Wook;Ur Soon-Chul
    • Journal of Powder Materials
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    • v.12 no.2 s.49
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    • pp.136-145
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    • 2005
  • Graphite-Ni composite powders were synthesized by mechanical alloying(MA) and spray drying(SD). Fabricated powders as well as commercial graphite-Ni powders were thermally sprayed on mild steel substrates using high velocity oxygen fuel (HVOF) thermal spray process and flame thermal spray process. The effects of several process parameters on related properties in thermally sprayed coatings have been investigated and correlated with microstructures in this study. The results indicated that the desired properties can be obtained when commercial powders were applied using HVOF process, while coating properties in case of MA powder application were inferior to those in HVOF process in so far. However, it is suggested that property enhancement can be obtained if the fraction of hexagonal graphite phase can be increased in mechanically alloyed powders.

Process Planning for Insert Metal of Weather Strip Using High Speed Rolling-Type (고속 압연방식을 이용한 Weather strip 용 Insert metal 공정설계)

  • Park, Ji-Su;Lee, Hyun-Woo;Jung, Sung-Yuen;Bae, Jun-Ho;Kim, Hwa-Young;Kim, Chul
    • Journal of the Korean Society for Precision Engineering
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    • v.28 no.11
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    • pp.1279-1287
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    • 2011
  • Weather strip is a functional component of a car body and doors for leaking protection, isolating outside noise and vibration reduction. Insert metal inserted to the weather strip plays a key role to keep the shape of the weather strip and increase its strength. Insert metal is mainly produced by a press process, which has low productivity and 40% material loss due to the scraps. To solve the problems, a high-speed rolling process for manufacturing the insert metal of weather strip is being attempted. In this study, the insert metal is manufactured by a high-speed rolling process, and its process variables: reduction, relative velocity of rollers and the number of passes, are optimized by using the FEA and the actual tests. The prototype was manufactured by the optimal process.

Research on Using Six Sigma Tool to Reduce the Core Process Time

  • Chung, Yi-Chan;Yen, Tieh-Min;Hsu, Yau-Wen;Tsai, Chih-Hung;Chen, Ching-Piao
    • International Journal of Quality Innovation
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    • v.9 no.1
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    • pp.94-102
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    • 2008
  • When facing the global severe competition, the enterprises all try their best to upgrade the quality, reduce the costs to reach the goal of customer satisfaction. Motorola was the earliest firm creating the term Six Sigma (6 ${\sigma}$); GE was the enterprise successfully fulfilling Six Sigma. The success of these two firms revealed the prominent effects and became the world-class model enterprises. The main purpose of promoting Six Sigma activity was to reduce the possible defects in the business process to the least through designing and monitoring business process in order to reach the goals such as the best quality and efficiency, the lowest costs, the shortest circular process time, maximum profits and customer satisfaction. This research used the Six Sigma technique to improve the business process of ceramics manufacturing plant and find out the major factors of slower core task time by the analytical process of Process Mapping, Pareto Chart, Simu18 simulation software and figures and proposed the improvement measures. Through the confirmation of the case companies, it successfully reduced the core process time and the organizational costs and increased the capacity.

Development of Risk Management Process for KSLV-I Program (KSLV-I 사업을 위한 위험관리 프로세스 개발)

  • Yoo, Il-Sang;Cho, Kwang-Rae
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.29 no.1
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    • pp.94-100
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    • 2006
  • The risk management is an organized method for identifying and measuring risk and for selecting, developing, and implementing options for the handling of risk. The risk management covers all programatic and technical factors which affect the system development performance, cost, and schedule. While technical issues are primary concern for systems engineering, the three elements(performance, cost, and schedule) must be balanced for a successful risk management process. This paper proposes the risk management process for the KSLV-I(Korea Space Launch Vehicle-I) program using computer-aided systems engineering tool, Cradle. The risk management process of KSLV-I program is similar to the general risk management process, but it has its own specific features to manage large-scale complex characteristics of KSLV-I program.

Discovering Redo-Activities and Performers' Involvements from XES-Formatted Workflow Process Enactment Event Logs

  • Pham, Dinh-Lam;Ahn, Hyun;Kim, Kwanghoon Pio
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.13 no.8
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    • pp.4108-4122
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    • 2019
  • Workflow process mining is becoming a more and more valuable activity in workflow-supported enterprises, and through which it is possible to achieve the high levels of qualitative business goals in terms of improving the effectiveness and efficiency of the workflow-supported information systems, increasing their operational performances, reducing their completion times with minimizing redundancy times, and saving their managerial costs. One of the critical challenges in the workflow process mining activity is to devise a reasonable approach to discover and recognize the bottleneck points of workflow process models from their enactment event histories. We have intuitively realized the fact that the iterative process pattern of redo-activities ought to have the high possibility of becoming a bottleneck point of a workflow process model. Hence, we, in this paper, propose an algorithmic approach and its implementation to discover the redo-activities and their performers' involvements patterns from workflow process enactment event logs. Additionally, we carry out a series of experimental analyses by applying the implemented algorithm to four datasets of workflow process enactment event logs released from the BPI Challenges. Finally, those discovered redo-activities and their performers' involvements patterns are visualized in a graphical form of information control nets as well as a tabular form of the involvement percentages, respectively.

BPMS Application for RFID based Manufacturing Operation Management (RFID 기반 생산운영 프로세스에서의 BPMS 적용)

  • Kim, Tae-Dong;Kang, Dong-Hun;Choi, Byoung-Kyu
    • IE interfaces
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    • v.21 no.4
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    • pp.435-443
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    • 2008
  • RFID (Radio Frequence Identification) is emerging technology and it is used for many fields. The research about RFID has been focused on hardware such as increasing hitting ratio. But recently the research about how and where RFID can apply is going on. Especially people are doing research about connecting RFID with existing information system. In this paper, when BPM manage RFID based manufacturing operation process, we show components which is needed and how we can obtain the components. And we apply this to straw manufacturing process on experiment. The claim-handling process and order-handling process which need improvement in straw manufacturing are chosen and we improve those processes. For executing the improved process, we define components which are database, data acquisition workflow and real-time event processing system and then we make prototype system.

A study on the Development of Systems Engineering Application Model for LRT based on MBSE (전산도구 기반의 경량전철사업 시스템엔지니어링 적용모델 SELRT 개발)

  • Han, Seok Youn;Kim, Joo Uk;Choi, Yo Cheol
    • Journal of the Korean Society of Systems Engineering
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    • v.8 no.1
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    • pp.9-19
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    • 2012
  • The Light Rail Transit Project is a large scaled project which takes several years in building a system. After construction, LRT system is operating for several tens of years. For these characteristics, the right application of systems engineering to LRT project greatly effects the project success. In this paper, we present systems engineering application model to LRT project i.e. SELRT which include systems engineering technical process, core technology management process, project support process. SELRT also has a module for the exchange of outputs in SE tool and PM tool. Systems engineering processes in SELRT mainly base on ISO/IEC 15288. In future, we expand the range of SE processes and improve the usability in SELRT. We expect that this model will contribute to improve the efficiency in LRT project and to success the LRT project.

A Study on the Framework of Mission Assurance for SE (시스템엔지니어링 강화를 위한 임무보증 Framework 연구)

  • Kim, Kwang Hae;Cho, Chul hoon;Ko, Jeong Hwan;Chung, Eui Seung
    • Journal of the Korean Society of Systems Engineering
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    • v.10 no.2
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    • pp.89-95
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    • 2014
  • In recent years, the United States have been several major failures of launch. As a result of these failures, activity of mission assurance valued. Mission assurance is defined as the application of systems engineering process towards the goal of achieving mission success. Therefore, mission assurance perform independent technical assessments throughout the concept and requirements definition, design, development, production, test, deployment, and operations phases. Space system program was emphasized the importance of the system engineering for that required huge cost and long term development. For this reason, independent review and verification of mission assurance is essential. Mission assurance gives us confidence to proceed with launch and best opportunity for mission success. In this study, framework of mission assurance is proposed by foreign case analysis.