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Real-Time DBR Scheduling in Internet Based Make-to-Order Manufacturing (인터넷을 통한 주문생산환경에서의 실시간 생산 DBR 스케줄링)

  • Han, Young-Geun;Kim, Yeon-Kyun
    • IE interfaces
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    • v.14 no.4
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    • pp.341-347
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    • 2001
  • This paper describes a real-time manufacturing scheduling system on Internet using DBR(Drum-Buffer-Rope) scheduling method. We intend to change company-oriented manufacturing scheduling, which has been used at most manufacturing companies, to customer-oriented manufacturing scheduling. Customers can not only choose product kinds, quantities and order due dates, but also evaluate optimum order due date by themselves in real-time through internet and then the results will be converted into practical manufacturing scheduling. If the company cannot meet the customer order due date, it will offer reliable and accurate information to the customers by suggesting the earliest order due date. To evaluate the customer order due date in real time, companies should be able to estimate their accurate production capacity. This research uses Goldratt's DBR scheduling method to realize that function. The DBR scheduling does not recognize the production capacity of the whole company, but only of the constraint resources which have a great effect on the company throughput. Thus, it can improve the customer service level as well as the profit by performing more dynamic and reliable scheduling through Internet.

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Newly Established Drug Delivery Systems Company Database (새로운 약물전달체계 회사 데이터베이스의 구축)

  • Han, In-Gu;Chung, Hes-Son
    • Journal of Pharmaceutical Investigation
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    • v.38 no.6
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    • pp.429-432
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    • 2008
  • Drug delivery systems (DDS) have entered mainstream in the pharmaceutical industry in the recent years. Major pharmaceutical companies as well as small or medium-sized biotechnology companies are developing various DDS-based products. We have established Drug Delivery System Company Database, which is an online searchable database of companies that develop DDS-based products and technologies or supply formulations and/or materials. Company summary, products and key technologies are listed in the database. DDS technology fields also include administration routes and indications of drugs. DDS terminologies, Statistical analysis, Useful Links, Glossary and Comments pages are also provided.

An Analysis on the Management Efficiency of the Fish-Paste Processing Industry (어묵 가공업의 경영효율성 분석)

  • Yang, Hyun-Joo;Song, Jung-Hun;Kwon, Hyeok-Seung
    • The Journal of Fisheries Business Administration
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    • v.52 no.3
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    • pp.15-25
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    • 2021
  • Base on the survey and financial statement on fish-paste processing company, this study aimed to estimate management efficiencies of fish-paste processing management using a data envelopment-analysis (DEA), In-depth interview and to find out their determinants. Model results show that the estimated mean management efficiencies obtained for the VRS and CRS DEA are 83.7% and 89.1%. In-depth interview results also show that efficiencies caused by scale of technical matter was greater than efficiencies caused by the scale of the company. Thus it implies that technical development is essential for achieving high-efficiency of fish-paste processing company more than expanding the size of company.

Theoretical Examination of the Pay-for-Performance Practice: Case of a Shipbuilding Company

  • Jun, Gyung-Ju
    • Journal of Navigation and Port Research
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    • v.37 no.5
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    • pp.471-480
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    • 2013
  • Pay-for-performance plans are some of widely used human resource practices in many firms, including shipbuilding, for productivity and motivational improvement purposes. Such plans play an important role in industries that are highly labor-intensive, and where effective management of human resources is critical to business operations, such as the shipbuilding industry. Those practices can have large impact on employee performance and ultimately company competitiveness. Research studies that show how such incentive plans improve productivity and reported pattern of adoption by firms have spurred the use and adoption in many firms. However, there are also researchers who point out that there are negative consequences to using incentive plans. Therefore it is important for companies to carefully consider the practices they use. In this paper, I discuss research findings that support the practices and critical viewpoints related to pay-for-performance plans. Research findings from Korean literature are, then, discussed. The shipbuilding industry is chosen because proper human resource management is critical in reducing turnover and increasing employee satisfaction. Through a shipbuilding company case, problems related to using pay-for-performance incentive plans and how they affect work-related issues of employee morale, cooperation, and teamwork will be discussed. While positive aspects have been emphasized to drive greater adoption among firms, the resulting consequences of the pay plans need to be seriously considered and improvements upon the plans made by firms. Improvement suggestions are discussed in the conclusions and implications.

In Vitro Metabolism of a New Neuroprotective Agent, KR-31543 in the Human Liver Microsomes : Identification of Human Cytochrome P450

  • Ji, Hye-Young;Lee, Seung-Seok;Yoo, Sung-Eun;Kim, Hosoon;Lee, Dong-Ha;Lim, Hong;Lee, Hye-Suk
    • Archives of Pharmacal Research
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    • v.27 no.2
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    • pp.239-245
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    • 2004
  • KR-31543, (2S,3R,4S)-6-amino-4-[N-(4-chlorophenyl)-N-(2 -methyl-2H-tetrazol-5-ylmethyl) amino]-3,4-dihydro-2-dimethoxymethyl-3-hydroxy-2-methyl-2H-1-benzopyran, is a new neuroprotective agent for preventing ischemia-reperfusion damage. This study was performed to identify the metabolic pathway of KR-31543 in human liver microsomes and to characterize cytochrome P450 (CYP) enzymes that are involved in the metabolism of KR-31543. Human liver microsomal incubation of KR-31543 in the presence of NADPH resulted in the formation of two metabolites, M1 and M2. M1 was identified as N-(4-chlorophenyl)-N-(2-methyl-2H-tetrazol-5-ylmethyl)amine on the basis of LC/MS/MS analysis with a synthesized authentic standard, and M2 was suggested to be hydroxy-KR-31543. Correlation analysis between the known CYP enzyme activities and the rates of the formation of M 1 and M2 in the 12 human liver microsomes have showed significant correlations with testosterone 6$\beta$-hydroxylase activity (a marker of CYP3A4). Ketoconazole, a selective inhibitor of CYP3A4, and anti-CYP3A4 monoclonal antibodies potently inhibited both N-hydrolysis and hydroxylation of KR-31543 in human liver microsomes. These results provide evidence that CYP3A4 is the major isozyme responsible for the metabolism of KR-31543 to M1 and M2.

Simulation of Beta Rays from Tritium with Cathode Rays (음극선을 이용한 삼중수소 베타선 모사)

  • Kim, KwangSin;Lee, Sook-Kyung;Son, Soon-Hwan;Lim, Hoon;Lee, Dong-Hwan
    • Journal of Radiation Industry
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    • v.2 no.3
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    • pp.141-148
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    • 2008
  • Beta rays emitted from tritium in titanium tritide film were simulated with cathode rays of a scanning electron microscope to investigate the effect of beta rays from tritium on semiconductor devices. The cathode ray currents, which vary with the change of applied energy and beam spot size, were measured with Faraday cup. The current from the semiconductor device irradiated with cathode rays at various conditions was measured. The cathode ray current increased with the increase of spot size to a maximum then decreased when the spot sized increased further. The magnitude of current produced in the semiconductor device is proportional to the magnitude of cathode ray current. The magnitude of cathode ray current at each energy level was matched to the intensity of beta ray to simulate the tritium beta ray spectrum. Then the semiconductor characteristics were analyzed with I-V curves.

Framework and Technology of Integrated Ship-Shore Information System

  • Zhang, Ying-Jun;Dong, Fang;Zhang, Xiu-Guo;Zhu, Fei-Xiang
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2004.08a
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    • pp.163-166
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    • 2004
  • Integrated Ship-Shore Information System makes use of advanced technology of marine mobile communication and extends the computer network of shipping company to ship. This system conveniently accomplishes the information exchange between company and ship, guarantees navigation safety and improves commercial performance. The framework of integrated ship-shore information system and the analysis of its function are provided in this paper. Meanwhile, the idea based on the specification of J2EE to build this system is put forward and the relevant technology is demonstrated.

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