• Title/Summary/Keyword: Research Evaluation

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Analysis of quercetin in extract of Hovenia dulcis Thunb (헛개나무과병추출물 중 퀘르세틴 분석)

  • Hu, SooJung;Oh, Jae-Myoung;Oh, Hyun-Suk;Moon, Myung-Hee;Bae, Yun-Young;Lee, Sung-Hye;Kim, Ji-An;Koo, Yong-Eui
    • Analytical Science and Technology
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    • v.29 no.6
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    • pp.255-260
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    • 2016
  • Based on the Korean Health Functional Food Act, health functional foods are dietary supplements containing nutrients or other substances that have nutritional or physiological effects. Since generic health functional food items have been expanded, this project was performed to develop a standardized analytical method of examining such sale items. The method exhibited high linearity in the quercetin calibration curve ($R^2$ > 0.999) over concentrations of $0-40{\mu}g/mL$. The limits of detection and quantitation for quercetin were $0.12{\mu}g/mL$ and $0.36{\mu}g/mL$, respectively, while quercetin recovery was 97.1-105.4 % with standard deviations of 1.15-3.11 %. To verify the accuracy of the analytical methods, the labeled amounts of purchased health functional foods were monitored. The recovery rate for multiple quercetin concentrations ranged from 82.5-105.1 % of the labeled amounts. Thus, the new method was suitable for all cases.

Guideline for the Clinical Trials Evaluation for Gastritis (위염치료제의 임상시험평가지침 연구)

  • Song, Yun-Kyoung;Jin, Sun-Kyung;Han, Eui-Sik;Ahn, Mee-Ryung;Jung, Ju-Yeon;Lee, Rhee-Da;Cho, Il-Yong;Kim, Dong-Sub;Ji, Eun-Hee;Park, Hyo-Young;Oh, Jung-Mi;Shin, Won;Lee, Sun-Hee;Kim, In-Kyu
    • YAKHAK HOEJI
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    • v.55 no.4
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    • pp.345-351
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    • 2011
  • Gastritis is the most common disease among Korean. The demand for the development of gastritis drugs has been increasing. Currently, however, there is no guideline available for the clinical evaluation of gastritis drugs worldwide. As a consequence, domestic and international pharmaceutical companies make errors in the drug development processes, and it becomes difficult for them to establish the scientific validity and objectivity of newly developed drugs. The objective of this study was to develop the Guideline for Clinical Trials Evaluation of Gastritis which can be used in improving the quality and consistency of clinical trials. First, we collected and reviewed the clinical trials on gastritis drugs that were available from Japan Pharmaceuticals and Medical Devices Agency and Korea Food and Drug Administration (KFDA), and investigated the recent research trends on clinical trials of gastritis drugs. Reviewers from KFDA and National Institute of Food and Drug Safety Evaluation and scientific experts from the pharmaceutical industries developed the guidelines through regularly scheduled meetings. Opinions and consultation from academic fields and industry experts were also obtained. This project will provide the clinical trial practitioners, investigator and reviewers the scientific and rational guidelines for performance and evaluation of clinical trials for gastritis drugs. Furthermore, we hope this guideline contributes to establishing the national competitiveness, improving the quality of clinical trial, and encouraging researches on drug development for gastritis.

Comparative Analysis on the Evaluation Systems of the Public R&D Programs in the Developed Countries (선진국공공연구개발프로그램 평가시스템의 비교분석)

  • 홍형득
    • Journal of Korea Technology Innovation Society
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    • v.4 no.3
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    • pp.275-290
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    • 2001
  • The frameworks for evaluation of national R&D programs reflect their various political and administrative cultures(Gibbons & Georghiou, 1987), and the structure of national R&D system. In this research the core research questions are : what is god evaluation\ulcorner What is being evaluated, by whom, by which criteria, for whom and what purpose\ulcorner In order to examine these general aims and answer these questions, in detail several objectives can be proposed on the process of this research. In this research, the national R&D programs will be considered in terms of the interface between evaluation and the wider policy-making process. The programs for case study are the Alvey program(UK), the Advanced Technology Program (US) and the Framework program(EU) . One of the characteristics of these programs is the well established evaluation systems they have. From the comparative analysis, we can withdraw some useful implication for Korean evaluation practice for national R&D programs. Evaluation system is social process and the way in which it is organized is critical to its outcome.

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Factor Structure, Validity and Reliability of The Teacher Satisfaction Scale (TSS) In Distance-Learning During Covid-19 Crisis: Invariance Across Some Teachers' Characteristics

  • Almaleki, Deyab A.;Bushnaq, Afrah A.;Altayyari, Basmah A.;Alshumrani, Amenah N.;Aloufi, Ebtesam H.;Alharshan, Najah A.;Almarwani, Ashwaq D.;Al-yami, Abeer A.;Alotaibi, Abeer A.;Alhazmi, Nada A.;Al-Boqami, Haya R.;ALhasani, Tahani N.
    • International Journal of Computer Science & Network Security
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    • v.21 no.7
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    • pp.17-34
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    • 2021
  • This study aimed to examine the Factor Structure of the teacher satisfaction scale (TSS) with distance education during the Covid-19 pandemic, as well as affirming the (Factorial Invariance) according to gender variable. It also aimed at identifying the degree of satisfaction according to some demographic variables of the sample. The study population consisted of all teachers in public education and faculty members in higher education in the Kingdom of Saudi Arabia. The (TSS) was applied to a random sample representing the study population consisting of (2399) respondents. The results of the study showed that the scale consists of five main factors, with a reliability value of (0.94). The scale also showed a high degree of construct validity through fit indices of the confirmatory factor analysis. The results have shown a gradual consistency of the measure's invariance that reaches the third level (Scalar-invariance) of the Measurement Invariance across the gender variable. The results also showed that the average response of the study sample on the scale reached (3.74) with a degree of satisfaction, as there are no statistically significant differences between the averages of the study sample responses with respect to the gender variable. While there were statistically significant differences in the averages with respect to the variable of the educational level in favor of the middle school and statistically significant differences in the averages attributed to the years of experience variable in favor of those whose experience is less than (5) years.

Performance Evaluation of the Research-Funding Agencies: Focused on the Evaluation Items of KOSEF (연구지원기관의 성과평가에 관한 연구: 한국과학재단에 대한 평가항목을 중심으로)

  • 이무신;엄기용;신용운
    • Journal of the Korean Operations Research and Management Science Society
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    • v.14 no.1
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    • pp.177-177
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    • 1989
  • This study concerns performance evaluation of the research-funding agencies focused on Korea Science and Engineering Foundation(KOSEF). On the basis of the constituents approach and the systems approach of organizational effectiveness theory, the evaluation items are derived reflecting generic characteristics of the research-funding agencies, and their priorities are determined using analytic hierarchy process(AHP). Three groups of constituents with differing interest and expections are identified, and their perceptions on the importance of the evaluation items are measured through questionnaire survey. Analyses show that the evaluation items perceived important by each constituency are significant different from one another. The implications of the result to the Government and KOSEF are discussed.

Multiple Trait Evaluation of Bivoltine Hybrids of Silkworm(Bombyx mori L.)

  • Babu, M.Ramesh;Chandrashekharaiah;Lakshmi, H.;Prasad, J.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.5 no.1
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    • pp.37-43
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    • 2002
  • Eighteen new bivoltine silkworm (Bombyx mori L.) hybrids developed at Andhra Pradesh State Sericul-ture Research and Development Institute, Hindupur are evaluated for 10 economic traits by following two multiple trait index methods, i.e., Subordinate Function and Evaluation Index for their economic merit. The hybrid genotype, APS6${\times}$APS11 with highest Subordinate function value of 8.2432 and highest average Evaluation Index of 61.67 ranked first. This hybrid is adjudicated as most promising hybrid and recommended for commercial use. Further, applicability of Subordinate Function Index Method is tested and recommended for application of multiple trait evaluation similar to Evaluation Index Method as the results obtained are comparable. Further, both these methods can be applied for confirmation of results.

Evaluation System Of Government Sponsored Research Institutes As Knowledge System (지식시스템으로서의 출연(연) 기관평가시스템 - 과학기술계 정부출연연구기관을 중심으로 -)

  • 김재영
    • Proceedings of the Korea Technology Innovation Society Conference
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    • 2000.11a
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    • pp.357-377
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    • 2000
  • This paper seeks to search a improved evaluation system of government sponsored research institutes(GSRI) as a knowledge system It begins with a brief review of the theory of knowledge and knowledge system This is followed by a search of the desirable conditions of the evaluation system of GSRI as a knowledge system These conditions presented are applied within the context of the current evaluation system of GSRI. Finally conclusions are drawn and directions for improvement of the system are outlined.

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A Study on the Performance Evaluation of Research and Development (연구개발의 실적평가에 관한 연구)

  • 김성희;하정진
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.19 no.39
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    • pp.163-170
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    • 1996
  • Several formerly independent trends including the increasing rate of technological change, the demand for greater efficiency and productivity in R&D and innovation. The purpose of this study is describe performance evaluation of research and development. Performance evaluation level of R&D have three levels: individual level, research group level, laboratory level. There are development evaluation factors and evaluation routin in each levels.

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Determination of Dibutyltin in Sediments Using Isotope Dilution Liquid Chromatography-Inductively Coupled Plasma Mass Spectrometry

  • Yim, Yong-Hyeon;Park, Ji-Youn;Han, Myung-Sub;Park, Mi-Kyung;Kim, Byung-Joo;Lim, Young-Ran;Hwang, Eui-Jin;So, Hun-Young
    • Bulletin of the Korean Chemical Society
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    • v.26 no.3
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    • pp.440-446
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    • 2005
  • A method is described for the determination of dibutyltin (DBT) in sediment by isotope dilution using liquid chromatography inductively-coupled plasma/mass spectrometry (LC-ICP/MS). To achieve the highest accuracy and precision, special attentions are paid in optimization and evaluation of overall processes of the analysis including extraction of analytes, characterization of the standards used for calibration and LC-ICP/MS conditions. An approach for characterization of natural abundance DBT standard has been developed by combining inductively-coupled plasma/optical emission spectrometry (ICP/OES) and LC-ICP/MS for the total Sn assay and the analysis of Sn species present as impurities, respectively. An excellent LC condition for separation of organotin species was found, which is suitable for simultaneous DBT and tributyltin (TBT) analysis as well as impurity analysis of DBT standards. Microwave extraction condition was also optimized for high efficiency while preventing species transformation. The present method determines the amount contents of DBT in sediments with expanded uncertainty of less than 5% and its result shows high degree of equivalence with reference values of an international inter-comparison and a certified reference material (CRM) within stated uncertainties.

Algorithms for Causality Evaluation of Adverse Events from Health/Functional Foods (건강기능식품 부작용 원인분석을 위한 알고리즘)

  • Lee, Kyung-Jin;Park, Kyoung-Sik;Kim, Jeong-Hun;Lee, Young-Joo;Yoon, Tae-Hyung;No, Ki-Mi;Park, Mi-Sun;Leem, Dong-Gil;Yoon, Chang-Yong;Jeong, Ja-Young
    • Journal of Food Hygiene and Safety
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    • v.26 no.4
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    • pp.302-307
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    • 2011
  • One of the most important objectives of post-marketing monitoring of dietary supplements is the early detection of unknown and unexpected adverse events (AEs). Several causality algorithms, such as the Naranjo scale, the RUCAM scale, and the M & V scale are available for the estimation of the likelihood of causation between a product and an AE. Based on the existing algorithms, the Korea Food & Drug Administration has developed a new algorithm tool to reflect the characteristics of dietary supplements in the causality analysis. However, additional work will be required to confirm if the newly developed algorithm tool has reasonable sensitivity and not to generate an unacceptable number of false positives signals.